المؤلفون: Gentry K. Cork, Jeffrey Thompson, Chad Slawson

المصدر: Frontiers in Endocrinology, Vol 9 (2018)

مصطلحات موضوعية: O-GlcNAc, OGT, OGA, mTOR (mammalian target of rapamycin), AMPK 5′ AMP-activated protein kinase, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/article/10.3389/fendo.2018.00522/fullTest; https://doaj.org/toc/1664-2392Test

الوصول الحر: https://doaj.org/article/4ff9e0348ace41ab88c9b207815fd065Test

المؤلفون: Lu Feng, Kai Zhang, Bo Liu, Tingting Jiang, Liang Ouyang, Guan Wang, Jiamei Li, Shiou Zhu, Junping Pei

المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 3015-3034 (2021)
Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: Target, ONRs, orphan nuclear receptors, Parkinson's disease, Small-molecule compound, MPP+, 1-methyl-4-phenylpyridinium, Autolysosome, GAPDH, glyceraldehyde 3-phosphate dehydrogenase, GBA, glucocerebrosidase β acid, Review, MPTP, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine, Disease, mTORC1, mTOR, the mammalian target of rapamycin, PD, Parkinson's disease, 0302 clinical medicine, CL, clearance rate, DAT, dopamine transporter, HDAC6, histone deacetylase 6, PD therapy, A2A, adenosine 2A, MYCBP2, MYC-binding protein 2, TFEB, transcription factor EB, AUTAC, autophagy targeting chimera, General Pharmacology, Toxicology and Pharmaceutics, SAS, solvent accessible surface, 0303 health sciences, α-syn, α-synuclein, ALP, autophagy-lysosomal pathway, AADC, aromatic amino acid decarboxylase, DJ-1, Parkinson protein 7, PI3K, phosphatidylinositol 3-kinase, COMT, catechol-O-methyltransferase, LUHMES, lund human mesencephalic, LRRK2, CMA, chaperone-mediated autophagy, KI, knockin, 030220 oncology & carcinogenesis, LRS, leucyl-tRNA synthetase, BBB, blood−brain barrier, SN, substantia nigra, IMPase, inositol monophosphatase, IPPase, inositol polyphosphate 1-phosphatase, HSPA8, heat shock 70 kDa protein 8, MAO-B, monoamine oxidase B, PREP, prolyl oligopeptidase, Parkinson's disease (PD), DR, dopamine receptor, PDE4, phosphodiesterase 4, AMPK, 5ʹAMP-activated protein kinase, 5-HT2C, serotonin 2C, SNCA, α-synuclein gene, TSC2, tuberous sclerosis complex 2, RM1-950, LIMP-2, lysosomal integrated membrane protein-2, CNS, central nervous system, 5-HT2A, Serotonin 2A, ER, endoplasmic reticulum, ATG, autophagy related protein, 03 medical and health sciences, PLC, phospholipase C, ROS, reactive oxygen species, ERRα, estrogen-related receptor alpha, SAR, structure–activity relationship, ULK1, UNC-51-like kinase 1, medicine, Autophagy, NMDA, N-methyl-d-aspartic acid, mAChR, muscarinic acetylcholine receptor, GWAS, genome-wide association study, LAMP2A, lysosome-associated membrane protein 2 A, Lamp2a, type 2A lysosomal-associated membrane protein, 030304 developmental biology, Parkin, parkin RBR E3 ubiquitin−protein ligase, PINK1, PTEN-induced kinase 1, ATTEC, autophagosome-tethering compound, ATP13A2, ATPase cation transporting 13A2, business.industry, ULK1, medicine.disease, LC3, light chain 3, PI3P, phosphatidylinositol 3-phosphate, SYT11, synaptotagmin 11, AUC, the area under the curve, UPS, ubiquitin−proteasome system, TFEB, DA, dopamine, Therapeutics. Pharmacology, business, BAF, bafilomycinA1, HSC70, heat shock cognate 71 kDa protein, Neuroscience, 3-MA, 3-methyladenine, F, oral bioavailability, LRRK2, leucine-rich repeat sequence kinase 2

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d12dab43aca56bfd6a912c2aa71297ffTest
http://www.sciencedirect.com/science/article/pii/S2211383521000642Test

المؤلفون: Maria Camilla Bergonzi, Anna Rita Bilia

المصدر: Journal of Ginseng Research, Vol 44, Iss 2, Pp 179-193 (2020)
Journal of Ginseng Research

مصطلحات موضوعية: 0301 basic medicine, FEF50, forced expiratory flow50, Energy and physical performance, SB, single-blind, Immune and cognitive functions, RVIP, rapid visual information processing, FER, forced expiratory ratio, HDL-c, high-density lipoprotein, MVV, maximum ventilation volume, Review, CDR, cognitive drug research, PGC-1α, proliferator-activated receptor gamma coactivator-1α, LA, lipoic acid, FEF75, forced expiratory flow75, Ginseng, 0302 clinical medicine, lcsh:Botany, PEFR, peak expiration flow rate, Medicine, media_common, CDRI, cognitive drug research index, Traditional medicine, TG, triglyceride, Chronic obstructive pulmonary disease, CO, crossover, AMPK, 5′ AMP-activated protein kinase, 3′,5′-AMP, adenosine 3′5′ monophosphate, lcsh:QK1-989, Safety profile, R, randomized, 030220 oncology & carcinogenesis, GACPs, good agricultural and collection practices, DB, double-blind, LDLc, low-density lipoprotein, Biotechnology, Drug, SIgA, secretory immunoglobulin A, ATP, adenosine triphosphate, SIRT1, sirtuin 1, FBG, fasting blood glucose, media_common.quotation_subject, Context (language use), HbAlc, glycated hemoglobin, PFTs, pulmonary function tests, Biochemistry, Genetics and Molecular Biology (miscellaneous), PEF, peak expiration flow, WHO, World Health Organization, GMPs, good manufacturing practices, S-SIgA, SIgA secretion rate, 03 medical and health sciences, FEV1, forced expiration volume in one second, GINSENG EXTRACT, pO2, partial oxygen pressure, G115, standardized root extract of P. ginseng Meyer, PC, placebo-controlled, Blood glucose and lipid regulation, Quality (business), G115 standardized ginseng extract, DER, drug extract ratio, SFR, saliva flow rate, business.industry, VLDL, very-low-density lipoprotein, PS, pilot study, VO2 max, maximal oxygen consumption, Clinical trial, TC, total cholesterol, 030104 developmental biology, Clinical research, Complementary and alternative medicine, COPD, chronic obstructive pulmonary disease, FVC, forced vital capacity, PG, parallel group, PaO2, blood oxygen pressure, business, FEV1/FVC, ratio of FEV1/FVC, HMPs, herbal medicinal products

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d9700de3065929919bceba8f514e74Test
http://www.sciencedirect.com/science/article/pii/S1226845319300090Test

المؤلفون: Prasenjit Manna, Khanchuila Shingnaisui, Jatin Kalita, Tapan Dey

المصدر: Journal of Ethnopharmacology

مصطلحات موضوعية: GSK-3β, Glycogen synthase kinase 3 beta, 0301 basic medicine, SARS, Severe acute respiratory syndrome, ABTS, 2,2′-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid), Anti-Inflammatory Agents, GPx, Glutathione peroxide, PGE2, Prostaglandin E2, medicine.disease_cause, Antioxidants, SOD, Superoxide dismutase, 0302 clinical medicine, Houttuynia cordata Thunb, DNP-BSA, 2,4-Dinitrophenol-Bovine Serum Albumin, Drug Discovery, NLRP3, NACHT, LRR and PYD domains-containing protein 3, IL, Interleukin, LTB4, Leukotriene B4, LPS, Lipopolysaccharide, HSV, Herpes simplex virus, NOS, Nitric oxide synthase, DPPH, 2,2-diphenyl-1-picrylhydrazyl, Traditional medicine, biology, MCP-1, Monocyte chemotactic protein 1 (CCL2), Houttuynia cordata, FRAP, Ferric-reducing antioxidant power, 030220 oncology & carcinogenesis, NF-κB, Nuclear factor kappa B, TNF-α, Tumor Necrosis Factor-α, medicine.symptom, Inflammation, COX, Cyclooxygenase, Article, Herbaceous perennial, GSH, Reduced glutathione, 03 medical and health sciences, AMPK, 5' AMP-activated protein kinase, In vivo, CYP, Cytochrome p450, medicine, Siddha, Animals, Humans, Houttuynia, MDA, Malondialdehyde, GDH, Glutamate dehydrogenase, Pharmacology, Saururaceae, TLR, Toll like receptor, Plant Extracts, business.industry, STZ, Streptozotocin, biology.organism_classification, NCBI, National Centre for Biotechnology Information, NO, Nitric Oxide, Oxidative Stress, 030104 developmental biology, Medicine, Traditional, Therapy, business, Relevant information, Oxidative stress, ROS, Reactive Oxygen Species

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88239e0fb28f6502ca6a369eca191d81Test
https://doi.org/10.1016/j.jep.2018.03.038Test

المؤلفون: Yi Ren, Han-Ming Shen

المصدر: Redox Biology
Redox Biology, Vol 25, Iss, Pp-(2019)

مصطلحات موضوعية: AMPK, AICAR, 5-aminoimidazole-4-carboxamide ribonucleotide, MAGE A3/6, melanoma-associated antigen 3/6, OXPHOS, oxidative phosphorylation, DHA, dehydroascorbic acid, PPAR, peroxisome proliferator-activated receptor, ACC, acetyl-CoA carboxylase, AMP-Activated Protein Kinases, Biochemistry, G6PD, glucose-6-phosphate dehydrogenase, NADPH, reduced nicotinamide adenine dinucleotide phosphate, 0302 clinical medicine, ARE, antioxidant response, 6PGD, 6-phosphogluconate dehydrogenase, HIF-1α, hypoxia-inducible factor 1-α, GR, glutathione reductase, PPP, the pentose phosphate pathway, Glycolysis, lcsh:QH301-705.5, Cancer, Glucose metabolism, α-KG, α-ketoglutaric acid, Kinase, FAS, fatty acid synthesis, GSSG, oxidized glutathione, SREBP, sterol regulatory element binding protein, ME, malic enzyme, Cell biology, ECM, extracellular matrix, NRF2, nuclear factor (erythroid-derived 2)-like 2, COX-2, cyclooxygenase-2, CRC, colorectal cancer, KEAP1, Kelch-like ECH-associated protein 1, lcsh:Medicine (General), 3PG, 3-phosphoglyceric acid, R-5P, ribose 5-phosphate, KRAS, Kirsten rat sarcoma, IDH, isocitrate dehydrogenase, GLUT1, glucose transporter 1, Pentose phosphate pathway, 6P-2DG, 6-phospho 2-deoxygluconate, mTORC1, mTOR Complex 1, Article, 03 medical and health sciences, LKB1, liver kinase B1, RAPTOR, regulatory-associated protein of mammalian target of rapamycin, ULK1, UNC-51-like kinase 1, Humans, PGC-1α, peroxisome proliferator-activated receptor γ coactivator 1-α, Protein kinase A, Fatty acid metabolism, HK, hexokinase, NQO1, NADPH dehydrogenase (quinone 1), Metabolic pathway, 030104 developmental biology, Glucose, 6P-G, 6-phosphogluconate, NADP+, nicotinamide adenine dinucleotide phosphate, CRM, calorie restriction mimetic, UCP2, mitochondrial uncoupling protein 2, CAT, catalase, 030217 neurology & neurosurgery, FAO, fatty acid oxidation, MAPK, mitogen-activated protein kinase, 0301 basic medicine, ERK2, extracellular signal-regulated kinase 2, GSH, reduced glutathione, PDAC, pancreatic ductal adenocarcinoma, Clinical Biochemistry, FASN, fatty acid synthase, 5TG, 5-thioglucose, HO-1, heme oxygenase 1, medicine.disease_cause, chemistry.chemical_compound, UBE2O, (E3-independent) E2 ubiquitin-conjugating enzyme, Neoplasms, FADH2, the quinone form flavin adenine dinucleotide, Trx, thioredoxin, BRAF, B-Raf proto-oncogene, 2DG-6P, 2-deoxyglucose 6-phosphate, lcsh:R5-920, GPx, glutathione peroxidase, Chemistry, AMPK, 5′ AMP-activated protein kinase, mTOR, the mechanistic target of rapamycin, Glc, glucose, NOX, NADPH oxidases, NADH, the reduced nicotinamide adenine dinucleotide, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, SGLT2, sodium/glucose cotransporter 2, Oxidation-Reduction, CaMKKβ, calcium/calmodulin-dependent protein kinase kinase β, TCA, tricarboxylic acid cycle, CPT1, carnitine palmitoyltransferase 1, PI3K, phosphoinositide-3-kinase, ETC, electron transport chain, G-6P, glucose 6-phosphate, TSC2, tuberous sclerosis complex 2, ROS, reactive oxygen species, MTP, mitochondrial trifunctional protein, NSCLC, non-small cell lung cancer, SOD, superoxide dismutase, medicine, Animals, 2DG, 2-deoxyglucose, MEF, mouse embryonic fibroblasts, TP, trifunctional protein, KO, knockout, MEK, MAPK Kinase, Organic Chemistry, SCD1, stearoyl-CoA desaturase-1, HNE, 4-hydroxy-2-nonenal, TRIM28, tripartite motif-containing 28, PTEN, phosphatase and tensin homolog, Oxidative Stress, lcsh:Biology (General), NAC, N-acetyl cysteine, Reactive oxygen species, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ed3374d5e3861a33fee3afc63c774d4Test
https://pubmed.ncbi.nlm.nih.gov/30853530Test

المؤلفون: Hong Tang, Ruili Yu, Shiying Liu, Ziru Li, Weizhen Zhang, Bahetiyaer Huwatibieke

المصدر: EBioMedicine

مصطلحات موضوعية: AMPK, 0301 basic medicine, HFD, high-fat diet, Irisin, medicine.medical_specialty, SREBP2, sterol regulatory element-binding transcription factor 2, White adipose tissue, AMP-Activated Protein Kinases, Diet, High-Fat, General Biochemistry, Genetics and Molecular Biology, Energy homeostasis, Mice, 03 medical and health sciences, chemistry.chemical_compound, AMP-activated protein kinase, Internal medicine, Myokine, medicine, Animals, Humans, Obesity, NCD, normal chow diet, biology, Cholesterol, BW, body weight, DIO, high fat diet-induced obese, AMPK, 5′ AMP-activated protein kinase, OA, oleic acid, FNDC5, fibronectin type β domain containing 5, WAT, white adipose tissue, CC, compound C, Hep G2 Cells, General Medicine, FNDC5, Fibronectins, 030104 developmental biology, Endocrinology, Gene Expression Regulation, Liver, chemistry, siRNA, small interfering RNA, biology.protein, SREBP2, Sterol regulatory element-binding protein 2, Signal Transduction, Sterol Regulatory Element Binding Protein 2, Research Paper

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3e6106db55d141ee654cbe7a2baf6daTest
https://doi.org/10.1016/j.ebiom.2016.02.041Test

المؤلفون: 전병환

المساهمون: 전태원, 체육교육과

مصطلحات موضوعية: 탈진적 운동, Exhaustive exercise, 췌장절제, Partial pancreatactomy, STZ, STZ(Streptozocin), GLUT-4, GLUT-4(Glucose transporter-4), AMPK, AMPK(5`AMP-activated protein kinase), ACC-2, ACC-2(Acetyl-CoA Carboxylase-2)

وصف الملف: vii, 101 장

العلاقة: http://dcollection.snu.ac.kr:80/jsp/common/DcLoOrgPer.jsp?sItemId=000000046707Test; http://hdl.handle.net/10371/59937Test

الإتاحة: http://hdl.handle.net/10371/59937Test
http://dcollection.snu.ac.kr:80/jsp/common/DcLoOrgPer.jsp?sItemId=000000046707Test