‘First week’ is the crucial period for deciding living donor liver transplantation in patients with acute-on-chronic liver failure
| العنوان: | ‘First week’ is the crucial period for deciding living donor liver transplantation in patients with acute-on-chronic liver failure |
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| المؤلفون: | Guan Huei Lee, Ananta Shrestha, Gamal Shiha, Kemal Fariz Kalista, Sombat Treeprasertsuk, Chen Yu, Pooja Jain, CE Eapen, Anand V. Kulkarni, V G Mohan Prasad, Ke Ma, Amna Subhan Butt, Guresh Kumar, Harshad Devarbhavi, Manoj Kumar, Rajan Vijayaraghavan, AKadir Dokmeci, Manoj Kumar Sahu, R. K. Dhiman, Pulivarthi Nageswara Rao, Mamun Al-Mahtab, Dong Joon Kim, Ajay Duseja, Samir Shah, Jose D. Sollano, Laurentius A. Lesmana, Shiv Kumar Sarin, Qin Ning, Diana A. Payawal, Zaigham Abbas, Vinod Arora, George K. K. Lau, Rinaldi Lesmana, Sunil Taneja, Piyush Kumar Sinha, Rakhi Maiwall, Ashish Goel, S. G. Tan, Ashok Choudhury, Fazal Karim, H. Ghazinyan, Saeed Hamid, Man-Fung Yuen, Zhongping Duan, Wasim Jafri, Viniyendra Pamecha, Akash Shukla |
| المصدر: | Hepatology International. 15:1376-1388 |
| بيانات النشر: | Springer Science and Business Media LLC, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Hepatology, business.industry, Incidence (epidemiology), Acute-On-Chronic Liver Failure, Middle Aged, Prognosis, medicine.disease, Colorectal surgery, Liver Transplantation, Cohort Studies, Sepsis, Internal medicine, Cohort, Living Donors, medicine, Humans, In patient, business, Living donor liver transplantation, Progressive disease, Retrospective Studies |
| الوصف: | Acute-on-chronic liver failure (ACLF) is a rapidly progressive illness with high short-term mortality. Timely liver transplant (LT) may improve survival. We evaluated various indices for assessment of the severity of liver failure and their application for eligibility and timing of living donor LT (LDLT). Altogether 1021 patients were analyzed for the severity and organ failure at admission to determine transplant eligibility and 28 day survival with or without transplant. The ACLF cohort [mean age 44 ± 12.2 years, males 81%) was of sick patients; 55% willing for LT at admission, though 63% of them were ineligible due to sepsis or organ failure. On day 4, recovery in sepsis and/or organ failure led to an improvement in transplant eligibility from 37% at baseline to 63.7%. Delay in LT up to 7 days led to a higher incidence of multiorgan failure (p |
| تدمد: | 1936-0541 1936-0533 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bdfd5af33b2fc89df7d7b790f716951Test https://doi.org/10.1007/s12072-021-10206-6Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....0bdfd5af33b2fc89df7d7b790f716951 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19360541 19360533 |
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