نتائج البحث - "ADAM, a disintegrin and metalloproteinase"

1

Trop-2 cleavage by ADAM10 is an activator switch for cancer growth and metastasis

المؤلفون: Antonella D'Amore, Angela Acciarito, Antonino Moschella, Zeeshan Ali, Khouloud Boujnah, Saverio Alberti, Anna Laura Aloisi, Pasquale Simeone, Rossano Lattanzio, Paola Zanna, Giovanna Vacca, Marco Trerotola, Emanuela Guerra, Martina Ceci, Valeria Garbo

المصدر: Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 4, Pp 415-428 (2021)
Neoplasia (New York, N.Y.)

مصطلحات موضوعية: 0301 basic medicine, LUADs, lung adenocarcinomas, Models, Molecular, Cancer Research, LUSCs, lung squamous cell cancers, SCC, squamous cell carcinoma, Metastasis, ADAM10 Protein, Mice, Cell growth, 0302 clinical medicine, Neoplasms, Neoplasm Metastasis, Original Research, Signaling activation, ADAM, a disintegrin and metalloproteinase, Mice, Inbred BALB C, medicine.diagnostic_test, Chemistry, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Transmembrane protein, 030220 oncology & carcinogenesis, MCF-7 Cells, HT29 Cells, Signal Transduction, wt, wild-type, Proteolysis, Transplantation, Heterologous, Molecular modeling, Cleavage (embryo), lcsh:RC254-282, 03 medical and health sciences, Antigens, Neoplasm, Cell Line, Tumor, medicine, Animals, Humans, Amino Acid Sequence, mAb, monoclonal antibody, Cell Proliferation, Activator (genetics), Cell Membrane, Cancer, Membrane Proteins, Epithelial Cells, medicine.disease, HCT116 Cells, Proteolytic processing, Trop, 030104 developmental biology, RIP, regulated intramembrane proteolysis, Cancer cell, Human cancer, Cancer research, Amyloid Precursor Protein Secretases, Cell Adhesion Molecules, Neoplasm Transplantation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6301cd7c391b29616c20ccc6f7b54dedTest
http://www.sciencedirect.com/science/article/pii/S1476558621000166Test

2

Endothelial glycocalyx degradation during sepsis: Causes and consequences

المؤلفون: Eric P. Schmidt, Matthew D. Rockstrom, Ryan C. Sullivan, Joseph A. Hippensteel

المصدر: Matrix Biology Plus
Matrix Biology Plus, Vol 12, Iss, Pp 100094-(2021)

مصطلحات موضوعية: Histology, DAMP, Damage-associated Molecular Pattern, QH301-705.5, Biophysics, Biochemistry, Microbiology, Sepsis, PG, Proteoglycan, ADAM, A Disintegrin and Metalloproteinase, ARDS, Acute respiratory distress syndrome, Genetics, medicine, Biology (General), Molecular Biology, LPS, Lipopolysaccharide, Glycosaminoglycans, Chemistry, HPSE-1/2, Heparanase-1/2, GAG, Glycosaminoglycan, Cell Biology, Ang2, Angiopoietin-2, Endothelial glycocalyx, medicine.disease, MMP, Matrix Metalloproteinase, carbohydrates (lipids), TIMP, Tissue inhibitors of matrix metalloproteinase, ANP, Atrial Natriuretic Peptide, Proteoglycans, Special Section on The Glycocalyx: Pathobiology and Repair, Edited by Jillian Richter & Ralph Sanderson, FFP, Fresh Frozen Plasma

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a055ff7791d39ede0280836f32f1d8Test
http://europepmc.org/articles/PMC8668992Test

3

RNA-seq data analysis of stimulated hepatocellular carcinoma cells treated with epigallocatechin gallate and fisetin reveals target genes and action mechanisms

المؤلفون: Fragiskos N. Kolisis, Heleni Loutrari, Panagiotis C. Agioutantis, Vasilios Kotsikoris

المصدر: Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 686-695 (2020)

مصطلحات موضوعية: TF, transcription factor, Hepatocellular carcinoma, EMT, epithelial to mesenchymal transition, RNA-Seq, DMSO, dimethyl sulfoxide, MMP9, Matrix Metallopeptidase 9, Biochemistry, Transcriptome, chemistry.chemical_compound, 0302 clinical medicine, Structural Biology, Gene expression, MMP11, Matrix Metallopeptidase 11, CTGF, Connective Tissue Growth Factor, CLIC3, Chloride Intracellular Channel 3, 0303 health sciences, HSPA2, Heat Shock Protein Family A (Hsp70) Member 2, ECM, extracellular matrix, SEM, standard error of mean, Epigallocatechin gallate, 3. Good health, Computer Science Applications, 030220 oncology & carcinogenesis, Research Article, STIM, stimulated, Biotechnology, Reactome Pathways, lcsh:Biotechnology, DEGs, differentially expressed genes, ADAM, a disintegrin and metalloproteinase with thrombospondin motifs, RNA-sequencing, Biophysics, FIS, fisetin, Biology, SERPINE1, Serpin Family E Member 1, MEM, minimum essential medium, 03 medical and health sciences, ADAMTS9, ADAM metallopeptidase with thrombospondin type 1 motif 9, lcsh:TP248.13-248.65, HSPB1, Heat Shock Protein Family B (Small) Member 1, GO, Gene Ontology, RT-qPCR, reverse transcription-quantitative real time PCR, Transcription factors, Genetics, PDGFRB, Platelet Derived Growth Factor Receptor Beta, Transcription factor, Gene, PI3K/AKT/mTOR pathway, ComputingMethodologies_COMPUTERGRAPHICS, 030304 developmental biology, Tumor microenvironment, Fisetin, Gene Ontology, chemistry, Cancer research, MMPs, matrix metalloproteinases, HCC, hepatocellular carcinoma, SD, standard deviation, EGCG, epigallocatechin gallate

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc2b7c496c6b1b9ca88af07fd67f672eTest
https://doi.org/10.1016/j.csbj.2020.03.006Test

4

Peptide-Based Inhibitors of ADAM and ADAMTS Metalloproteinases

المؤلفون: Stefano Pluda, Ylenia Mazzocato, Alessandro Angelini

المصدر: Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences, Vol 8 (2021)

مصطلحات موضوعية: 0301 basic medicine, QH301-705.5, Mini Review, Peptide, Computational biology, Matrix metalloproteinase, Biology, Biochemistry, Genetics and Molecular Biology (miscellaneous), Biochemistry, Mini review, 03 medical and health sciences, 0302 clinical medicine, Settore BIO/10 - Biochimica, Molecular Biosciences, Biology (General), Molecular Biology, A-disintegrin and metalloproteinase (ADAM), A-disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS), metalloproteinase, peptide inhibitors, linear peptides, cyclic peptides, macrocycles, chemistry.chemical_classification, Metalloproteinase, ADAMTS, linear peptides, Rational design, A-disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS), cyclic peptides, peptide inhibitors, Small molecule, carbohydrates (lipids), 030104 developmental biology, macrocycles, chemistry, 030220 oncology & carcinogenesis, A-disintegrin and metalloproteinase (ADAM), metalloproteinase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0150607bd4589c2860f5d1603440359dTest
http://europepmc.org/articles/PMC8335159Test

5

Extracellular events impacting human papillomavirus infections: Epithelial wounding to cell signaling involved in virus entry

المؤلفون: Michelle A. Ozbun

المصدر: Papillomavirus Research
Papillomavirus Research, Vol 7, Iss, Pp 188-192 (2019)

مصطلحات موضوعية: Receptor complex, viruses, Cell, GAG, glycosaminoglycan, Medicine, Papillomaviridae, A2t, the annexin A2/S100A10 heterotetramer, Sdc, syndecan, ADAM, a disintegrin and metalloproteinase, 0303 health sciences, HPV infection, virus diseases, Epithelial wounding, 3. Good health, Cell biology, ECM, extracellular matrix, Extracellular Matrix, MMP, matrix metalloproteinase, Infectious Diseases, medicine.anatomical_structure, FAK, focal adhesion kinase, Host-Pathogen Interactions, GF, growth factor, RTK, receptor tyrosine kinase, Signal Transduction, HPV16, Cell signaling, Keratinocyte signaling, Heparan sulfonated proteoglycans, HS, heparan sulfate, HPV, human papillomavirus, Papillomavirus infection, Virus, Article, lcsh:Infectious and parasitic diseases, Oncogenic HPV genotypes, 03 medical and health sciences, Viral entry, Virology, Extracellular, Humans, lcsh:RC109-216, 030304 developmental biology, 030306 microbiology, business.industry, Capsid conformational changes, Papillomavirus Infections, Epithelial Cells, Virus Internalization, medicine.disease, EGFR, epidermal growth factor receptor, PI3K, phosphatidyl inositol 3-kinase, Viral Receptor, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7251c6de935a25473ff8355606a1b347Test
http://europepmc.org/articles/PMC6514438Test

6

TGF-β1 facilitates MT1-MMP-mediated proMMP-9 activation and invasion in oral squamous cell carcinoma cells

المؤلفون: Takeshi Suzuki, Chikako Asada, Hirari Yamahana, Yoshihiro Uto, Risa Takatsuka, Minoru Terashima, Takahisa Takino

المصدر: Biochem Biophys Rep
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 27, Iss, Pp 101072-(2021)

مصطلحات موضوعية: Gelatinases, QH301-705.5, Cell, PBS, phosphate-buffered saline, Biophysics, QD415-436, Matrix metalloproteinase, Biochemistry, Article, Extracellular matrix, Invasion, FBS, fetal bovine serum, TGF-β1, medicine, Basal cell, Biology (General), Con A, concanavalin A, OSCC, oral squamous cell carcinoma, TGF, transforming growth factor, ADAM, a disintegrin and metalloproteinase, ECM, DMEM, Dulbecco's modified Eagle's medium, MMP, TIMP, tissue inhibitor of MMP, biology, Chemistry, Oral cancer, ECM, extracellular matrix, MMP, matrix metalloproteinase, MT1-MMP, membrane type-1 MMP, medicine.anatomical_structure, Concanavalin A, biology.protein, Collagenase, Cancer research, MAPK, mitogen-activated protein kinase, Research Article, medicine.drug, Transforming growth factor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e001543e7e8c01d95600f1c24b5b697Test
https://doi.org/10.1016/j.bbrep.2021.101072Test

7

A potent endocytosis inhibitor Ikarugamycin up-regulates TNF production

المؤلفون: Takehito Asakawa, Takashi Nagaishi, Kiichiro Tsuchiya, Mai Murakami, Tomoaki Mochimaru, Michio Onizawa, Chiharu Sakuma, Ryuichi Okamoto, Hiromasa Ohira, Chikako Saito, Rie Hikichi, Shigeru Oshima, Mamoru Watanabe, Ai Minamidate, Yuichi Hiraoka

المصدر: Biochemistry and Biophysics Reports, Vol 27, Iss, Pp 101065-(2021)
Biochemistry and Biophysics Reports

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f482f004afe8c745a364c5d5502fc1f4Test
https://doi.org/10.1016/j.bbrep.2021.101065Test

8

دورية أكاديمية

ADAM-8, a metalloproteinase, drives acute allergen-induced airway inflammation

المؤلفون: Paulissen, Geneviève, Rocks, Natacha, Guéders, Maud, Bedoret, Denis, Crahay, Céline, Quesada Calvo, Florence, Hacha, Jonathan, Bekaert, Sandrine, Desmet, Christophe, Foidart, Jean-Michel, Bureau, Fabrice, Noël, Agnès, Cataldo, Didier

المصدر: European Journal of Immunology, 41 (2), 380-91 (2011)

مصطلحات موضوعية: ADAM: A Disintegrin And Metalloproteinase, ADAM-8-/-: ADAM-8 deficient mice, ADAM-8+/+: ADAM-8 wild-type mice, sADAM-8: soluble form of ADAM-8, Life sciences, Anatomy (cytology, histology, embryology.) & physiology, Sciences du vivant, Anatomie (cytologie, histologie, embryologie.) & physiologie

العلاقة: info:eu-repo/grantAgreement/EC/FP7/201279; urn:issn:0014-2980; urn:issn:1521-4141; https://orbi.uliege.be/handle/2268/77446Test; info:hdl:2268/77446; https://orbi.uliege.be/bitstream/2268/77446/1/Paulissen%20G%202011.pdfTest; scopus-id:2-s2.0-78851471704; info:pmid:21268008

الإتاحة: https://doi.org/10.1002/eji.200940286Test
https://orbi.uliege.be/handle/2268/77446Test
https://orbi.uliege.be/bitstream/2268/77446/1/Paulissen%20G%202011.pdfTest

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9

Overexpression of the A Disintegrin and Metalloproteinase ADAM15 is linked to a Small but Highly Aggressive Subset of Prostate Cancers

المصدر: Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 4, Pp 279-287 (2017)
Neoplasia (New York, N.Y.)

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, ADAM15, Oncogene Proteins, Fusion, Disintegrins, FISH, fluorescence in situ hybridization, TMPRSS2, transmembrane protease, serine 2, Gene Expression, Prostate cancer, 0302 clinical medicine, Prostate, In Situ Hybridization, Fluorescence, Sequence Deletion, MAP3K7, mitogen-activated protein kinase kinase kinase 7, Aged, 80 and over, ADAM, a disintegrin and metalloproteinase, Tissue microarray, biology, Serine Endopeptidases, Middle Aged, Prognosis, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Immunohistochemistry, MMP, matrix metalloproteinase, Prostate-specific antigen, medicine.anatomical_structure, 030220 oncology & carcinogenesis, CHD1, chromodomain-helicase-DNA-binding protein 1, Disease Progression, PCA3, Adult, Original article, TMPRSS2, lcsh:RC254-282, 03 medical and health sciences, Transcriptional Regulator ERG, medicine, Biomarkers, Tumor, TMA, tissue microarray, PTEN, Humans, FOXP1, forkhead box protein P1, Aged, Neoplasm Staging, Membrane Proteins, Prostatic Neoplasms, Prostate-Specific Antigen, medicine.disease, Survival Analysis, PTEN, phosphatase and tensin homolog, ADAM Proteins, 030104 developmental biology, ETS, erythroblast transformation-specific, PSA, prostate specific antigen, biology.protein, Cancer research, ERG, erythroblast transformation-specific (ETS) related gene, Neoplasm Grading, Neoplasm Recurrence, Local

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e68ac5e92d6d87cc3f75e79a6f751b0aTest
http://www.sciencedirect.com/science/article/pii/S1476558616301798Test

10

Circadian rhythm and sleep-wake systems share the dynamic extracellular synaptic milieu

المؤلفون: Rebecca A. Prosser, Joanna M. Cooper, Kathryn A. Halter

المصدر: Neurobiology of Sleep and Circadian Rhythms
Neurobiology of Sleep and Circadian Rhythms, Vol 5, Iss, Pp 15-36 (2018)

مصطلحات موضوعية: 0301 basic medicine, REMS, rapid eye movement sleep, TTFL, transcriptional-translational negative feedback loop, LRP-1, low density lipoprotein receptor-related protein 1, Bmal1, Brain and muscle Arnt-like-1 gene, NMDAR, NMDA receptor, Per, period gene, tPA, tissue-type plasminogen activator, VLPO, ventrolateral preoptic, Sleep-wake system, Extracellular matrix, Behavioral Neuroscience, chemistry.chemical_compound, 0302 clinical medicine, Ncam, neural cell adhesion molecule gene, Cry, cryptochrome gene, LTP, long-term potentiation, dNlg4, drosophila neuroligin-4 gene, NCAM, neural cell adhesion molecule protein, ADAM, A disintegrin and metalloproteinase, NST, nucleus of the solitary tract, Cytoskeleton, Receptor, Neurotransmitter, DD, dark-dark, lcsh:QH301-705.5, TNF, tumor necrosis factor, RSD, REM sleep disruption, Cell adhesion molecules, Suprachiasmatic nucleus, Cell adhesion molecule, Nrx, neurexin gene, uPA, urokinase-type plasminogen activator, ECM, extracellular matrix, LC, locus coeruleus, Neurology, nNOS, neuronal nitric oxide synthase protein, PAI-1, plasminogen activator inhibitor-1, LH, lateral hypothalamus, BDNF, brain-derived neurotrophic factor, MMP, matrix metalloproteinases, Intracellular, AMPAR, AMPA receptor, nNOS, neuronal nitric oxide synthase gene, Nrl, neuroligin gene, VP, vasopressin, Pulmonary and Respiratory Medicine, CRY, cryptochrome protein, Endo N, endoneuraminidase N, Biology, VTA, ventral tegmental area, Article, lcsh:RC321-571, EEG, electroencephalogram, SWS, slow wave sleep, Extracellular proteases, 03 medical and health sciences, Extracellular, P2, purine type 2 receptor, Circadian rhythms, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, NO, nitric oxide, LD, light-dark, SCN, suprachiasmatic nucleus, PER, period protein, ECS, extracellular space, BMAL1, Brain and muscle Arnt-like-1 protein, GFAP, glial fibrillary acidic protein, uPAR, uPA receptor, VIP, vasoactive intestinal polypeptide, PPT, peduculopontine tegmental nucleus, Ig, immunoglobulin, PSA, polysialic acid, IL, interleukin, 030104 developmental biology, lcsh:Biology (General), chemistry, Astrocytes, Neurology (clinical), Neuroscience, 030217 neurology & neurosurgery, CAM, cell adhesion molecules

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9784b59b0d2c00d8e0ea1156b937fff4Test
https://pubmed.ncbi.nlm.nih.gov/31236509Test

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