المؤلفون: de Jesus Carrion, Steven, Abbondante, Serena, Clark, Heather L, Marshall, Michaela E, Mouyna, Isabelle, Beauvais, Anne, Sun, Yan, Taylor, Patricia R, Leal, Sixto M, Armstrong, Brittany, Carrera, William, Latge, Jean‐Paul, Pearlman, Eric

المصدر: European Journal of Immunology. 49(6)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Emerging Infectious Diseases, Eye Disease and Disorders of Vision, Infectious Diseases, 2.2 Factors relating to the physical environment, 2.1 Biological and endogenous factors, Aetiology, Infection, Animals, Aspergillosis, Aspergillus fumigatus, Chitin Synthase, Chitinases, Humans, Keratitis, Mice, Inbred C57BL, Neutrophils, Virulence, Acidic mammalian chitinase, Corneal infection, Chitin synthase, Neutrophil, Immunology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/1tn5b7tbTest

المؤلفون: Van Dyken, Steven J, Locksley, Richard M

المصدر: Journal of Allergy and Clinical Immunology. 142(2)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Immunology, Animals, Chitin, Chitinases, Environmental Exposure, Extinction, Biological, Homeostasis, Humans, Immunity, Mucosal, Mammals, Mice, Polysaccharides, Respiratory Tract Diseases, Acidic mammalian chitinase, age-related disease, chitotriosidase, chitin, chitinase, fibrosis, epithelium, innate lymphoid cell, interleukins, interstitial lung disease, polysaccharide, pulmonary fibrosis, Allergy

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/8bv6r3nnTest

المؤلفون: Diaz, Roberto Efrain

مصطلحات موضوعية: Biochemistry, Biophysics, Molecular biology, Acidic mammalian chitinase, Diversity Equity Inclusion and Justice, pH

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/0m96z59vTest

المؤلفون: Marzena Mazur, Jakub Włodarczyk, Mikołaj Świerczyński, Radzisław Kordek, Marcin M. Grzybowski, Jacek Olczak, Jakub Fichna

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 4; Pages: 2159

مصطلحات موضوعية: acidic mammalian chitinase, colitis, inflammatory bowel diseases, inhibitor

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Biochemistry; https://dx.doi.org/10.3390/ijms23042159Test

الإتاحة: https://doi.org/10.3390/ijms23042159Test

المؤلفون: S. Makarova I., D. Mitrofanov V., A. Shintyapina B., E. Komova G., V. Zelenskaya V., T. Kartseva V., E. Kondyurina G., V. Vavilin A., С. Макарова И., Д. Митрофанов В., А. Шинтяпина Б., Е. Комова Г., В. Зеленская В., Т. Карцева В., Е. Кондюрина Г., В. Вавилин А.

المساهمون: the work was carried out within the framework of the AAAA-A18-118012490236-3 budget project using the equipment of the Proteomic Analysis Center for Collective Use, registry number 201716, работа выполнена в рамках бюджетного проекта АААА-А18-118012490236-3 с использованием оборудования ЦКП «Протеомный анализ», реестровый № 201716

المصدر: The Siberian Journal of Clinical and Experimental Medicine; Том 36, № 4 (2021); 92-98 ; Сибирский журнал клинической и экспериментальной медицины; Том 36, № 4 (2021); 92-98 ; 2713-265X ; 2713-2927

مصطلحات موضوعية: gene of human acidic mammalian chitinase, bronchial asthma, rs12033184, rs3806448, ген кислой хитиназы человека, бронхиальная астма

وصف الملف: application/pdf

العلاقة: https://cardiotomsk.elpub.ru/jour/article/view/1292/668Test; Grayson M.H., Feldman S., Prince B.T., Patel P.J., Matsui E.C., Apter A.J. Advances in asthma in 2017: Mechanisms, biologics, and genetics. J. Allergy Clin. Immunol. 2018;142(5):1423–1436. DOI:10.1016/j.jaci.2018.08.033.; García-Sánchez A., Isidoro-García M., García-Solaesa V., Sanz C., Hernández-Hernández L., Padrón-Morales J. et al. Genome-wide association studies (GWAS) and their importance in asthma. Allergol. Immunopathol. (Madr.). 2015;43(6):601–608. DOI:10.1016/j.aller.2014.07.004.; Ober C. Asthma genetics in the Post-GWAS Erа. Ann. Am. Thorac. Soc. 2016;13(1):S85–S90. DOI:10.1513/AnnalsATS.201507-459MG.; Masaki K., Fukunaga K., Matsusaka M., Kabata H., Tanosaki T., Mochimaru T. et al. Characteristics of severe asthma with fungal sensitization. Ann. Allergy Asthma Immunol .2017;119(3):253–257. DOI:10.1016/j.anai.2017.07.008.; Agache I., Lau S., Akdis C.A., Smolinska S., Bonini M., Cavkaytar O.J. et al. EAACI Guidelines on Allergen Immunotherapy: House dust mite-driven allergic asthma. Allergy. 2019;74(5):855–873. DOI:10.1111/all.13749.; dbSNP. CHIA. URL: https://www.ncbi.nlm.nih.gov/snp/?term=CHIATest; Chatterjee R., Batra J., Das S., Sharma S.K., Ghosh B. Genetic аssociation of аcidic mammalian chitinase with atopic asthma and serum total IgE levels. J. Allergy Clin. Immunol. 2008;122 (1):202–208,208.e1–7. DOI:10.1016/j.jaci.2008.04.030.; Zhu Y., Yan X., Zhai C., Yang L., Li M. Association between risk of asthma and gene polymorphisms in CHI3L1 and CHIA: A systematic meta-analysis. BMC Pulm. Med. 2017;17(1):193. DOI:10.1186/s12890-017-0515-2.; Bierbaum S., Nickel R., Koch A., Lau S., Deichmann K.A., Wahn U. et al. Polymorphisms and haplotypes of acid mammalian chitinase are associated with bronchial asthma. Am. J. Respir. Crit. Care Med. 2005;172(12):1505–1509. DOI:10.1164/rccm.200506-890OC.; Wu A.C., Lasky-Su J., Rogers C.A., Klanderman B.J., Litonjua A. Polymorphisms of chitinases are not associated with asthma. J. Allergy Clin. Immunol. 2010;125(3):754–757,757.e1–757.e2. DOI:10.1016/j.jaci.2009.12.995.; Пузырев В.П., Кучер А.Н. Эволюционно-онтогенетические аспекты патогенетики хронических болезней человека. Генетика. 2011;47(12):1573–1585.; Степанов В.А. Геномы, популяции, болезни: этническая геномика и персонифицированная медицина. Acta Naturae. 2010;2(4):18–34.; dbSNP. rs3806448. URL: https://www.ncbi.nlm.nih.gov/snp/rs3806448#-frequency_tabTest; dbSNP. rs12033184. URL: https://www.ncbi.nlm.nih.gov/snp/rs12033184#frequency_tabTest; Tjoelker L.W., Gosting L., Frey S., Hunter C.L., Trong H.L., Steiner B. et al. Structural and functional definition of the human chitinase chitin-binding domain. J. Biol. Chem. 2000;275(1):514–520. DOI:10.1074/jbc.275.1.514.; Ober C., Chupp G.L. The chitinase and chitinase-like proteins: A review of genetic and functional studies in asthma and immune-mediated diseases. Curr. Opin. Allergy Clin. Immunol. 2009;9(5):401–408. DOI:10.1097/ACI.0b013e3283306533.; Van Eijk M., van Roomen C.P., Renkema G.H., Bussink A.P., Andrews L., Blommaart E.F. et al. Characterization of human phagocyte-derived chitotriosidase, a component of innate immunity. Int. Immunol. 2005;17(11):1505–1512. DOI:10.1093/intimm/dxh328.; Wu A.C., Lasky-Su J., Rogers C.A., Klanderman B.J., Litonjua A. Fungal exposure modulates the effect of polymorphisms of chitinases on emergency department visits and hospitalizations. Am. J. Respir. Crit. Care Med. 2010;182(7):884–889. DOI:10.1164/rccm.201003-0322OC.; Вавилин В.А., Макарова С.И., Ляхович В.В., Гавалов С.М. Ассоциация полиморфных генов ферментов биотрансформации ксенобиотиков с предрасположенностью к бронхиальной астме у детей с наследственной отягощенностью и без таковой. Генетика. 2002;38(4):539–545.; Карунас А.С., Юнусбаев Б.Б., Федорова Ю.Ю., Гималова Г.Ф., Рамазанова Н.Н., Гурьева Л.Л. и др. Полногеномный анализ ассоциации бронхиальной астмы в Волго-Уральском регионе России. Молекулярная биология. 2011;45(6):992–1003.; https://cardiotomsk.elpub.ru/jour/article/view/1292Test

الإتاحة: https://doi.org/10.29001/2073-8552-2021-36-4-92-98Test
https://doi.org/10.1016/j.jaci.2018.08.033Test
https://doi.org/10.1016/j.aller.2014.07.004Test
https://doi.org/10.1513/AnnalsATS.201507-459MGTest
https://doi.org/10.1016/j.anai.2017.07.008Test
https://doi.org/10.1111/all.13749Test
https://doi.org/10.1016/j.jaci.2008.04.030Test
https://doi.org/10.1186/s12890-017-0515-2Test
https://doi.org/10.1164/rccm.200506-890OCTest
https://doi.org/10.1016/j.jaci.2009.12.995Test

المؤلفون: Nance, J. Philip, Vannella, Kevin M, Worth, Danielle, David, Clément, Carter, David, Noor, Shahani, Hubeau, Cedric, Fitz, Lori, Lane, Thomas E, Wynn, Thomas A, Wilson, Emma H, Denkers, Eric Y

المصدر: PLoS Pathogens. 8(11)

مصطلحات موضوعية: alternatively activated macrophages, toxoplasma-gondii infection, acidic mammalian chitinase, cell-mediated-immunity, inducible nitric-oxide, cd4(+) t-cells, ifn-gamma, differential expression, functional plasticity, allergic inflammation

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/3s19j4x8Test

المؤلفون: SpiroMeta Consortium, Int COPD Genetics Consortium, Understanding Soc Sci Grp

المساهمون: Institute for Molecular Medicine Finland

مصطلحات موضوعية: GENOME-WIDE ASSOCIATION, ACIDIC-MAMMALIAN-CHITINASE, LD SCORE REGRESSION, LUNG-FUNCTION, EXTRACELLULAR-MATRIX, PREDOMINANT EMPHYSEMA, CONNECTIVITY MAP, ATOPIC ASTHMA, RISK LOCI, GWAS, 3111 Biomedicine, 1184 Genetics, developmental biology, physiology

وصف الملف: application/pdf

العلاقة: This work was supported by the Prince Mahidol Award Youth Program Scholarship (P. Sakornsakolpat); NHLBI R01HL084323, R01HL113264, R01HL089856, and P01HL105339 (E.K.S.); K08HL136928 (B.D.H.), the Parker B. Francis Research Opportunity Award (B.D.H.); and R01HL113264, R01HL137927, P01HL105339, and P01HL132825 (M.H.C.). This research was conducted by using the UK Biobank resource under application numbers 20915 (M.H.C.) and 648 (M.D.T.). Please refer to the Supplementary Note for full acknowledgements. Funding bodies had no role in the design of the study, the collection, analysis, or interpretation of the data, or the writing of the manuscript.; SpiroMeta Consortium , Int COPD Genetics Consortium & Understanding Soc Sci Grp 2019 , ' Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations ' , Nature Genetics , vol. 51 , no. 3 , pp. 494-+ . https://doi.org/10.1038/s41588-018-0342-2Test; 85062145797; f42124af-b233-4434-9a86-3bdd758ef914; http://hdl.handle.net/10138/313327Test; 000459947200017

الإتاحة: http://hdl.handle.net/10138/313327Test

المؤلفون: Maiko Uehara, Eri Tabata, Kazuhiro Ishii, Akira Sawa, Misa Ohno, Masayoshi Sakaguchi, Vaclav Matoska, Peter Bauer, Fumitaka Oyama

المصدر: Genes; Volume 9; Issue 5; Pages: 244

مصطلحات موضوعية: acidic mammalian chitinase, asthma, chitinolytic activity, chitotriosidase, crab-eating monkey, human, mouse, nonhuman primate model, qPCR, species-specific gene expression

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Animal Genetics and Genomics; https://dx.doi.org/10.3390/genes9050244Test

الإتاحة: https://doi.org/10.3390/genes9050244Test

المؤلفون: Akinori Kashimura, Masahiro Kimura, Kazuaki Okawa, Hirotaka Suzuki, Atsushi Ukita, Satoshi Wakita, Kana Okazaki, Misa Ohno, Peter O. Bauer, Masayoshi Sakaguchi, Yasusato Sugahara, Fumitaka Oyama

المصدر: International Journal of Molecular Sciences, Vol 16, Iss 2, Pp 4028-4042 (2015)

مصطلحات موضوعية: acidic mammalian chitinase, allergy, asthma, catalytic domain, chitin-binding activity, chitinolytic activity, colloidal and crystalline chitin, food processing, innate immunity, mouse, Biology (General), QH301-705.5, Chemistry, QD1-999

وصف الملف: electronic resource

العلاقة: http://www.mdpi.com/1422-0067/16/2/4028Test; https://doaj.org/toc/1422-0067Test

الوصول الحر: https://doaj.org/article/b4709be3da2a4666abbad342eb06c303Test

المؤلفون: Robert Koralewski, Michał Kowalski, Krzysztof Matyszewski, Sylwia Olejniczak, Piotr L. Sklepkiewicz, Michal Piotrowicz, Czestkowski Wojciech J, Michal Mlacki, Adam Golebiowski, Karolina Dzwonek, Barbara Dymek, Magdalena Salamon, Bartlomiej Borek, Piotr Niedziejko, Agnieszka Bartoszewicz, Marcin Nowotny, Agnieszka Zagozdzon, Mariusz Gruza, Agnieszka Napiorkowska-Gromadzka, Aneta Bartlomiejczak, Pawel Dobrzanski, Marzena Mazur, Gleb Andryianau, Magdalena Kania, Jakub Golab, Pluta Elzbieta, Karol Jedrzejczak, Witold Mozga, Marcin Mazurkiewicz, Tomasz Rejczak, Jacek Olczak, Sylwia Piasecka, Aleksandra Rymaszewska

المصدر: Journal of Medicinal Chemistry. 63:15527-15540

مصطلحات موضوعية: 0303 health sciences, Lung, biology, Chemistry, ACIDIC MAMMALIAN CHITINASE, medicine.disease, 01 natural sciences, respiratory tract diseases, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, Idiopathic pulmonary fibrosis, medicine.anatomical_structure, Drug Discovery, Immunology, Chitinase, medicine, biology.protein, Molecular Medicine, 030304 developmental biology, Asthma

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::a2dd9844a8fb40d1518481d781cdfd6dTest
https://doi.org/10.1021/acs.jmedchem.0c01179Test