يعرض 1 - 9 نتائج من 9 نتيجة بحث عن '"ABCB1 – ATP-binding cassette"', وقت الاستعلام: 0.95s تنقيح النتائج
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    دورية أكاديمية
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    المصدر: Acta Pharmaceutica Sinica. B
    Acta Pharmaceutica Sinica B, Vol 11, Iss 7, Pp 1885-1902 (2021)

    مصطلحات موضوعية: ABCC1, ATP binding cassette subfamily C member 1, IC50, half maximal inhibitory concentration, Multidrug resistance, Pharmacology, NADPH, reduced nicotinamide adenine dinucleotide phosphate, F, bioavailability, chemistry.chemical_compound, PCR, polymerase chain reaction, 0302 clinical medicine, MDR, multidrug resistance, ECL, electrochemiluminescence, t1/2, elimination half-life, LC–MS, liquid chromatography coupled with mass spectrometry, N.D., not detected, General Pharmacology, Toxicology and Pharmaceutics, BBB, blood–brain barrier, media_common, ATF3, activating transcription factor 3, 0303 health sciences, Chemistry, ABC, ATP-binding cassette, NMPA, National Medical Products Administration, PXR, pregnane X receptor, SDS-PAGE, sodium dodecyl sulfate-polyacrylamide gel electrophoresis, HBSS, Hankʹs balanced salt solution, ABCB1, Combination chemotherapy, Prodrug, Marsdenia tenacissima, Cmax, peak concentration, Paclitaxel, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, 030220 oncology & carcinogenesis, BHI, brain heart infusion, Original Article, AUC0–∞, area under plasma concentration vs. time curve, MRT, mean residence time, Drug, media_common.quotation_subject, RM1-950, Vd, volume of distribution, ABCB1, ATP binding cassette subfamily B member 1, UIC-2, mouse monoclonal ABCB1 antibody, ABCG2, ATP binding cassette subfamily G member 2, CYP, cytochrome P450 isozyme, PI, propidium iodide, TEER, transepithelial electrical resistance, 03 medical and health sciences, PBS, phosphate buffer saline, FBS, fetal bovine serum, Dox, doxorubicin, In vivo, POP, polyoxypregnane, medicine, 030304 developmental biology, EVOM, epithelial tissue voltohmmeter, Tmax, time for peak concentration, Cancer, LBE, lowest binding energy, PE, phycoerythrin, medicine.disease, Multiple drug resistance, Polyoxypregnane, Papp, apparent permeability, N.A., not applicable, Cancer cell, H&E, hematoxylin and eosin, MDR1a, multidrug resistance protein 1a, Therapeutics. Pharmacology, qPCR, quantitative PCR, M. tenacissima, Marsdenia tenacissima, CL, clearance, SD, standard derivation

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    المصدر: Computational and Structural Biotechnology Journal
    Computational and Structural Biotechnology Journal, Vol 17, Iss, Pp 160-176 (2019)

    مصطلحات موضوعية: cIAP1, cellular inhibitor of apoptosis protein, BTK, Bruton's tyrosine kinase, HDAC, histone deacetylase, Review Article, PROTAC, proteolysis targeting chimeras, HTS, high-throughput screening, PI3K, phosphatidylinositol-3-kinase, VHL, Von Hippel-Lindau, Biochemistry, GST, glutathione S-transferase, 0302 clinical medicine, EZH2, enhancer of zeste homolog 2, Structural Biology, BET, bromodomain and extra-terminal, GCN5, general control nonderepressible 5, POI, protein of interest, TBK1, TANK-Binding kinase 1, CRBN, Cereblon, DC50, the compound concentration that results in 50% target protein degradation, FLT3, FMS-like tyrosine kinase-3, 0303 health sciences, biology, Chemistry, Drug discovery, ABCB1, ATP-binding cassette sub-family B member 1, Small molecule, Computer Science Applications, Cell biology, Ubiquitin ligase, AHR, aryl hydrogen receptor, FRS2, fibroblast growth factor receptor substrate 2, RIPK2, receptor-interacting serine/threonine-protein kinase 2, 030220 oncology & carcinogenesis, Proteome, AD, Alzheimer's disease, ERK1, extracellular signal-regulated kinase 1, MDM2, mouse double-minute 2 homolog, RTK, receptor tyrosine kinase, ERα, estrogen receptor alpha, TRIM24, tripartite motif-containing 24 (also known as TIF1α), Biotechnology, DHODH, Dihydroorotate dehydrogenase, lcsh:Biotechnology, Biophysics, Protein degradation, Bivalent ligand, Bcl6, B-cell lymphoma 6, CLIPTAC, click-formed proteolysis targeting chimera, PROTAC, 03 medical and health sciences, CDK9, cyclin dependent kinase 9, ERRα, estrogen-related receptor alpha, lcsh:TP248.13-248.65, Genetics, SARM, selective androgen receptor modulator, Transcription factor, PEG, polyethylene glycol, 030304 developmental biology, PLK-1, polo-like kinase 1, PCAF, P300/CBP-associated factor, Proteasome, Brd4, bromodomain 4, MetAP-2, methionine aminopeptidase-2, Chimera, ALK, anaplastic lymphoma kinase, Cereblon, CK2, Casein kinase 2, Degrader, Aβ, amyloid-β, SNIPER, specific and non-genetic IAP-dependent protein eraser, GPCR, G-protein coupled receptor, RAR, retinoic acid receptor, biology.protein

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    دورية أكاديمية
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    المصدر: Seminars in Cancer Biology

    مصطلحات موضوعية: IGF, insulin growth factor, MRN, MER11-RAD50-NBS1, Skp2, S-phase kinase-associated protein 2, DNA Repair, ER, estrogen receptor, FasL, fas ligand, GICs, glioma-initiating cells, TCF/LEF, T-cell factor/lymphoid enhancer factor, NBS1, Nijmegen breakage syndrome 1, ATM, Ataxia-telangiectasia mutated, FHRE, forkhead response element, AURKA, aurora kinase A, Mst1, macrophage stimulating 1, ERK, extracellular signal-regulated kinase, Bim, B-cell lymphoma 2 interacting mediator, RTKs, receptor tyrosine kinases, Neoplasms, XRCC1, X-ray cross-complementing group 1, Cell Self Renewal, BER, base excision repair, MDR1, multidrug resistance protein 1, AMPK, adenosine monophosphate-activated protein kinase, OTUB1, OUT domain-containing ubiquitin aldehyde-binding protein 1, Forkhead Box Protein O3, Fox, forkhead box, ABCB1, ATP-binding cassette sub-family B member 1, PI3K, phosphatidylinositol 3-kinase, TRAIL, tumour necrosis factor-related apoptosis inducing ligand, TKIs, tyrosine kinase inhibitors, VEGF, vascular endothelial growth factor, Gene Expression Regulation, Neoplastic, PIP3, phosphatidylinositol- 3,4,5-trisphosphate, GADD45, DNA damage-inducible protein 45, AML, acute myeloid leukaemia, SOD-2, superoxide dismutase, IFNɣ, interferon-ɣ, PKB, protein kinase B, CSCs, cancer stem cells, NAMPT, nicotinamide-phosphribosyltransferase, Antineoplastic Agents, BRCA1, breast cancer susceptibility gene product 1, MMR, mismatch repair, mTOR, mammalian target of rapamycin, SSBs, single-strand breaks, ER+ve, estreogen receptor positive, Article, DDR, DNA damage response, DSBs, double strands breaks, ESR1, estrogen receptor alpha gene, EXO1, exonuclease 1, miRs, Micro-RNAs, ROS, reactive oxygen species, NER, nucleotide excision repair, MCL, mantle cell lymphoma, MEK, mitogen-activated protein kinase kinase, Humans, Cks1, cyclin-dependent kinases regulatory subunit 1, SCs, stem cells, Cell Proliferation, CML, chronic myeloid leukaemia, EGF, epidermal growth factor, Forkhead Box Protein M1, EGFR, epidermal growth factor receptor, PA, Psammaplysene A, ChIP-seq, chromatin immunoprecipitation with massively parallel DNA sequencing, Drug Resistance, Neoplasm, BRCA2, breast cancer-associated gene 2, NHEJ, non-homologous end joining, BRIP1, BRCA1-interacting protein-terminal helicase 1, Rb2, retinoblastoma-related p130, HR, homologous recombination, HCC, hepatocellular carcinoma, JNK/SAPK, c-Jun N-terminal kinase/stress activated protein kinase, Sox1, sex determining region Y box 2, PDK, phosphoinositide-dependent kinase

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    المؤلفون: Liwu Fu, Lihua Huang

    المصدر: Acta Pharmaceutica Sinica. B
    Acta Pharmaceutica Sinica B, Vol 5, Iss 5, Pp 390-401 (2015)

    مصطلحات موضوعية: MAPK/ERK pathway, IGF, insulin growth factor, BCL2L11/BIM, BCL2-like 11, STAT, signal transducers and activators of transcription, Resistance, PDGFs, platelet-derived growth factors, Review, GAS6, growth-arrest-specific protein 6, PI3K, phosphatidylinositol-3-kinase, ABCC1, ATP binding cassette, sub-family C, member 1, T790M, PIK3CA, phosphatidylinositol-4,5-bisphosphate 3-kinase,catalytic subunit alpha, FGFs, fibroblast growth factors, Mechanisms, Medicine, BCL-2, B-cell CLL/lymphoma-2, CML, chronic myelogenous leukemia, Epidermal growth factor receptor, ABC, ATP binding cassette, General Pharmacology, Toxicology and Pharmaceutics, RAF, rapidly accelerated fibrosarcoma, BH3, BCL2-homology domain 3, ABCB1, ATP binding cassette, sub-family B, member 1, biology, ABCG2, ATP binding cassette, sub-family G, member 2, IGF-1R, IGF-1 receptor, TKIs, tyrosine kinase inhibitors, VEGF, vascular endothelial growth factor, VEGFR, vascular endothelial growth factor receptor, HER, human epidermal receptor, FGFRs, fibroblast growth factor receptors, IL-6R, IL-6 receptor, medicine.drug, EGFR-TKIs, epidermal growth factor receptor tyrosine kinase inhibitors, RTK, tyrosine kinase receptor, ERK1/2, extracellular signal-regulated kinases, ABCC10, ATP binding cassette, sub-family C, member 10, EGFR, BRAF, v-RAF murine sarcoma viral oncogene homolog B1, PDGFRs, platelet-derived growth factor receptors, EMT, epithelial mesenchymal transition, JAK, janus kinase, AKT, protein kinase B, Gefitinib, CRKL, Crk-like protein, NSCLC, non-small cell lung cancer, PTEN, RAS, rat sarcoma, Protein kinase B, EML4, echinoderm microtubule-associated protein-like 4, SOCS3, suppressor of cytokine signaling 3, PI3K/AKT/mTOR pathway, SF, scatter factor, business.industry, GAS6, ALK, anaplastic lymphoma kinase, lcsh:RM1-950, TKs, tyrosine kinases, PTEN, phosphatase and tensin homolog, respiratory tract diseases, EGFR, epidermal growth factor receptor, IL, interleukin, lcsh:Therapeutics. Pharmacology, TKIs, IGFBPs, IGF-binding proteins, EGFRvIII, EGFR variant III, Cancer research, biology.protein, HGF, hepatocyte growth factor, AXL, Anexelekto, business, MAPK, mitogen-activated protein kinase, MEK, mitogen-activated protein kinase

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    دورية أكاديمية