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المؤلفون: Lu Feng, Kai Zhang, Bo Liu, Tingting Jiang, Liang Ouyang, Guan Wang, Jiamei Li, Shiou Zhu, Junping Pei
المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 3015-3034 (2021)
Acta Pharmaceutica Sinica. Bمصطلحات موضوعية: Target, ONRs, orphan nuclear receptors, Parkinson's disease, Small-molecule compound, MPP+, 1-methyl-4-phenylpyridinium, Autolysosome, GAPDH, glyceraldehyde 3-phosphate dehydrogenase, GBA, glucocerebrosidase β acid, Review, MPTP, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine, Disease, mTORC1, mTOR, the mammalian target of rapamycin, PD, Parkinson's disease, 0302 clinical medicine, CL, clearance rate, DAT, dopamine transporter, HDAC6, histone deacetylase 6, PD therapy, A2A, adenosine 2A, MYCBP2, MYC-binding protein 2, TFEB, transcription factor EB, AUTAC, autophagy targeting chimera, General Pharmacology, Toxicology and Pharmaceutics, SAS, solvent accessible surface, 0303 health sciences, α-syn, α-synuclein, ALP, autophagy-lysosomal pathway, AADC, aromatic amino acid decarboxylase, DJ-1, Parkinson protein 7, PI3K, phosphatidylinositol 3-kinase, COMT, catechol-O-methyltransferase, LUHMES, lund human mesencephalic, LRRK2, CMA, chaperone-mediated autophagy, KI, knockin, 030220 oncology & carcinogenesis, LRS, leucyl-tRNA synthetase, BBB, blood−brain barrier, SN, substantia nigra, IMPase, inositol monophosphatase, IPPase, inositol polyphosphate 1-phosphatase, HSPA8, heat shock 70 kDa protein 8, MAO-B, monoamine oxidase B, PREP, prolyl oligopeptidase, Parkinson's disease (PD), DR, dopamine receptor, PDE4, phosphodiesterase 4, AMPK, 5ʹAMP-activated protein kinase, 5-HT2C, serotonin 2C, SNCA, α-synuclein gene, TSC2, tuberous sclerosis complex 2, RM1-950, LIMP-2, lysosomal integrated membrane protein-2, CNS, central nervous system, 5-HT2A, Serotonin 2A, ER, endoplasmic reticulum, ATG, autophagy related protein, 03 medical and health sciences, PLC, phospholipase C, ROS, reactive oxygen species, ERRα, estrogen-related receptor alpha, SAR, structure–activity relationship, ULK1, UNC-51-like kinase 1, medicine, Autophagy, NMDA, N-methyl-d-aspartic acid, mAChR, muscarinic acetylcholine receptor, GWAS, genome-wide association study, LAMP2A, lysosome-associated membrane protein 2 A, Lamp2a, type 2A lysosomal-associated membrane protein, 030304 developmental biology, Parkin, parkin RBR E3 ubiquitin−protein ligase, PINK1, PTEN-induced kinase 1, ATTEC, autophagosome-tethering compound, ATP13A2, ATPase cation transporting 13A2, business.industry, ULK1, medicine.disease, LC3, light chain 3, PI3P, phosphatidylinositol 3-phosphate, SYT11, synaptotagmin 11, AUC, the area under the curve, UPS, ubiquitin−proteasome system, TFEB, DA, dopamine, Therapeutics. Pharmacology, business, BAF, bafilomycinA1, HSC70, heat shock cognate 71 kDa protein, Neuroscience, 3-MA, 3-methyladenine, F, oral bioavailability, LRRK2, leucine-rich repeat sequence kinase 2
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d12dab43aca56bfd6a912c2aa71297ffTest
http://www.sciencedirect.com/science/article/pii/S2211383521000642Test -
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المؤلفون: Akiko Hayashi, Karin Miyamoto, Akihiro Ohishi, Kentaro Nishida, Ryoko Nakanishi, Kazuki Nagasawa, Mizuka Imai, Kyoko Kobayashi
المصدر: Toxicology Reports, Vol 4, Iss, Pp 172-180 (2017)
Toxicology Reportsمصطلحات موضوعية: 0301 basic medicine, Health, Toxicology and Mutagenesis, CP, circumvallate papillae, Cancer therapy, Pharmacology, Sour taste, DMSO, dimethyl sulfoxide, Toxicology, Adverse effect, Protein expression, Article, Bortezomib, 03 medical and health sciences, NaCl, sodium chloride, HE, hematoxylin-eosin, stomatognathic system, immune system diseases, lcsh:RA1190-1270, hemic and lymphatic diseases, HCl, hydrochloric acid, medicine, MSG, mono sodium glutamate, Chemotherapy, cardiovascular diseases, neoplasms, Multiple myeloma, lcsh:Toxicology. Poisons, Control level, AADC, aromatic amino acid decarboxylase, Chemistry, QHCl, quinine hydrochloride, medicine.disease, 030104 developmental biology, Taste disorder, Proteasome inhibitor, BSA, bovine serum albumin, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9654ab5e59b789eeeffc0456e381c4aTest
http://www.sciencedirect.com/science/article/pii/S2214750017300136Test -
3دورية أكاديمية
المساهمون: The Pennsylvania State University CiteSeerX Archives
مصطلحات موضوعية: parkin gene, PET, 18F]dopa, 11C]raclopride, SPM Abbreviations, AADC = aromatic amino acid decarboxylase, AI = asymmetry index, BA = Brodmann
وصف الملف: application/pdf
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المؤلفون: Masayo Mori-Kojima, Chiaki Kawamoto, Satoshi Hara, Daniel Metzger, Katsuya Miyajima, Chiho Sumi-Ichinose, Tamae Ohye, Toshikuni Sasaoka, Hiroshi Ichinose, Nae Saito
المساهمون: Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)
المصدر: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2021, 296, pp.100544. ⟨10.1016/j.jbc.2021.100544⟩
The Journal of Biological Chemistryمصطلحات موضوعية: Male, 0301 basic medicine, sympathoadrenal system, DOPA, 3,4-dihydroxyphenylalanine, Sympathetic Nervous System, Dopamine, CA, catecholamine, [SDV]Life Sciences [q-bio], APUD, amine precursor uptake and decarboxylation, Biochemistry, Mice, chemistry.chemical_compound, Catecholamines, tyrosine hydroxylase, Adrenal Glands, pancreas, Neurotransmitter, ComputingMilieux_MISCELLANEOUS, Mice, Knockout, Neurons, NA, noradrenaline, Aromatic L-amino acid decarboxylase, Kidney, AADC, aromatic amino acid decarboxylase, D1R, dopamine D1 receptor, medicine.anatomical_structure, Organ Specificity, stomach, LAT, L-type amino acid transporter, TAM, tamoxifen, Research Article, medicine.drug, medicine.medical_specialty, Tyrosine 3-Monooxygenase, TH, tyrosine hydroxylase, 3,4-dihydroxyphenylalanine, DBH, dopamine β-hydroxylase, heart, 03 medical and health sciences, Internal medicine, medicine, Animals, Sympathoadrenal system, Molecular Biology, Gene knockout, 030102 biochemistry & molecular biology, Tyrosine hydroxylase, AD, adrenaline, cKO, conditional KO, Cell Biology, Biosynthetic Pathways, gene KO, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, adrenal, chemistry, noradrenaline, Catecholamine, DA, dopamine
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc82740686aefef1da6e4fb1ac3ccb2Test
https://doi.org/10.1016/j.jbc.2021.100544Test -
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المؤلفون: S. AlAhmed, Joe Herbert
المصدر: Neuroscience
مصطلحات موضوعية: Male, hippocampus, Hippocampus, Cell Count, KPBS, potassium phosphate buffer, Rats, Sprague-Dawley, chemistry.chemical_compound, 0302 clinical medicine, Drug Delivery Systems, Corticosterone, ANOVA, analysis of variance, 0303 health sciences, AADC, aromatic amino acid decarboxylase, General Neuroscience, Neurogenesis, Adrenalectomy, ADX, adrenalectomized/adrenalectomy, progenitor cells, strain differences, Adult Stem Cells, neurogenesis, Glucocorticoid, Selective Serotonin Reuptake Inhibitors, IHC, immunohistochemistry, medicine.drug, medicine.medical_specialty, corticoids, Neuroscience(all), Biology, 03 medical and health sciences, Neuropharmacology, HPA, hypothamalo-pituitary–adrenal, Species Specificity, Precursor cell, Internal medicine, Fluoxetine, medicine, Animals, Circadian rhythm, Progenitor cell, 030304 developmental biology, Cell Proliferation, Analysis of Variance, Dentate gyrus, Rats, Endocrinology, Ki-67 Antigen, chemistry, CT, circadian time, Dentate Gyrus, 030217 neurology & neurosurgery
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c4bb11c4a1e04836a994d660f09cd4bTest
https://pubmed.ncbi.nlm.nih.gov/18930787Test