المؤلفون: Timothy D. Klasson, Edward L. LaGory, Hongjuan Zhao, Star K. Huynh, Ioanna Papandreou, Eui Jung Moon, Amato J. Giaccia

المصدر: Cancer & Metabolism, Vol 10, Iss 1, Pp 1-17 (2022)

مصطلحات موضوعية: Clear cell renal cell carcinoma (ccRCC), Lipid droplets, Ferroptosis, Lipid metabolism, Acyl-CoA synthetase 3 (ACSL3), 5-lipoxygenase (5-LOX), Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2049-3002Test

الوصول الحر: https://doaj.org/article/31c54fc7899d4d009ae61cd9a6805ec7Test

المؤلفون: Mahesh G, Anil Kumar K, Reddanna P

المصدر: Journal of Inflammation Research, Vol Volume 14, Pp 253-263 (2021)

مصطلحات موضوعية: inflammation, cyclooxygenase (cox), nsaids, coxibs, microsomal pge synthase-1 (mpges-1), 15- hydroxy prostaglandin dehydrogenase (15-pgdh), 5-lipoxygenase (5-lox), Pathology, RB1-214, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

العلاقة: https://www.dovepress.com/overview-on-the-discovery-and-development-of-anti-inflammatory-drugs-s-peer-reviewed-article-JIRTest; https://doaj.org/toc/1178-7031Test

الوصول الحر: https://doaj.org/article/bfcd628dde3a4c4fb225c41e59b955f1Test

المؤلفون: Esmear, Tenille, Twilley, Danielle, Thipe, Velaphi Clement, Katti, Kattesh V., Mandiwana, Vusani, Kalombo, Michel Lonji, Ray, Suprakas Sinha, Rikhotso-Mbungela, Rirhandzu, Bovilla, Venugopal Reddy, Madhunapantula, SubbaRao, Langhanshova, Lenka, Roma-Rodrigues, Catarina, Fernandes, Alexandra R., Baptista, Pedro, Hlati, Silvestre, Pretorius, Judey, Lall, Namrita

مصطلحات موضوعية: Lung cancer, Ethanolic plant extracts, Antiproliferative activity, Helichrysum odoratissimum Sweet (HO), Anti-inflammatory activity, A549 lung cancer cells, Gold nanoparticles, Cyclooxygenase 2 (COX-2), 5-lipoxygenase (5-LOX), In vivo angiogenesis, NAD(P)H quinone oxidoreductase-1 (NQO1), Yolk sac membrane assay, Microscopy

وصف الملف: application/pdf

العلاقة: Esmear, T., Twilley, D., Thipe, V.C. et al. 2024, 'Anti-inflammatory and antiproliferative activity of Helichrysum odoratissimum sweet. Against lung cancer', South African Journal of Botany, vol. 166, pp. 525-538, doi : 10.1016/j.sajb.2024.01.056.; 0254-6299 (print); 1727-9321 (online); http://hdl.handle.net/2263/94810Test

الإتاحة: https://doi.org/10.1016/j.sajb.2024.01.056Test
http://hdl.handle.net/2263/94810Test

المؤلفون: Cerchia, Carmen, Küfner, Laura, Werz, Oliver, Lavecchia, Antonio

المساهمون: Cerchia, Carmen, Küfner, Laura, Werz, Oliver, Lavecchia, Antonio

مصطلحات موضوعية: 5-Lipoxygenase (5-LOX), 5-Lipoxygenase-activating protein (FLAP), Drug discovery, Inflammation, Inhibitor, Virtual screening

العلاقة: volume:263; firstpage:115932; journal:EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY; https://hdl.handle.net/11588/951613Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85178651472

الإتاحة: https://doi.org/10.1016/j.ejmech.2023.115932Test
https://hdl.handle.net/11588/951613Test

المؤلفون: Na Ni, Jiaying Zheng, Wenji Wang, Linyong Zhi, Qiwei Qin, Youhua Huang, Xiaohong Huang

المصدر: International Journal of Molecular Sciences; Volume 22; Issue 22; Pages: 12597

مصطلحات موضوعية: cytosolic phospholipase A2, SGIV, glycerophospholipids, cyclooxygenase (COX), 5-Lipoxygenase (5-LOX)

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Molecular Toxicology; https://dx.doi.org/10.3390/ijms222212597Test

الإتاحة: https://doi.org/10.3390/ijms222212597Test

المؤلفون: Youhua Huang, Na Ni, Jiaying Zheng, Qiwei Qin, Linyong Zhi, Xiaohong Huang, Wenji Wang

المصدر: International Journal of Molecular Sciences, Vol 22, Iss 12597, p 12597 (2021)
International Journal of Molecular Sciences; Volume 22; Issue 22; Pages: 12597
International Journal of Molecular Sciences

مصطلحات موضوعية: cyclooxygenase (COX), food.ingredient, QH301-705.5, Iridovirus, Phospholipases A2, Cytosolic, Aquaculture, Phosphatidylserines, Biology, Virus Replication, Catalysis, Article, Inorganic Chemistry, chemistry.chemical_compound, food, Phospholipase A2, Animals, cytosolic phospholipase A2, SGIV, glycerophospholipids, 5-Lipoxygenase (5-LOX), Physical and Theoretical Chemistry, Biology (General), Molecular Biology, QD1-999, Spectroscopy, Gene knockdown, Singapore, Arachidonate 5-Lipoxygenase, Organic Chemistry, Fishes, General Medicine, Phosphatidylserine, Computer Science Applications, Cell biology, Chemistry, Viral replication, chemistry, biology.protein, Phosphatidylcholines, Ectopic expression, Arachidonic acid, Intracellular

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea8540684d81046b7c84a03a7df6966bTest
https://www.mdpi.com/1422-0067/22/22/12597Test

المؤلفون: Fengtong Zuo, Hui Liu, Huijun Wu

المصدر: BioScience Trends. 2017, 11(4):439

المؤلفون: Atsushi Nakajima, Aya Ihara, Hirokazu Takahashi, Koichiro Wada, Masato Yoneda, Nobutaka Fujisawa

المصدر: Journal of Pharmacological Sciences. 2007, 103(1):24

المؤلفون: Zhang, Mengdi, Xia, Zhonghua, Yan, Aixia

المساهمون: Yan, AX (reprint author), Beijing Univ Chem Technol, Dept Pharmaceut Engn, State Key Lab Chem Resource Engn, POB 53,15 BeiSanHuan East Rd, Beijing 100029, Peoples R China., Yan, AX (reprint author), Peking Univ, State Key Lab Nat & Biomimet Drugs, Beijing, Peoples R China., Beijing Univ Chem Technol, Dept Pharmaceut Engn, State Key Lab Chem Resource Engn, POB 53,15 BeiSanHuan East Rd, Beijing 100029, Peoples R China., Peking Univ, State Key Lab Nat & Biomimet Drugs, Beijing, Peoples R China.

المصدر: SCI

مصطلحات موضوعية: Human 5-lipoxygenase (5-LOX) inhibitors, Structure-activity relationship (SAR), Self-organizing map (SOM), Support vector machine (SVM), Multilayer perceptron network (MLP), SUPPORT VECTOR MACHINES, ARTIFICIAL NEURAL-NETWORKS, SELF-ORGANIZING MAPS, DRUG DISCOVERY, BIOLOGICAL EVALUATION, 5-LOX INHIBITORS, HIGHLY POTENT, LIPOXYGENASE, DERIVATIVES, INDOLES

العلاقة: MOLECULAR DIVERSITY.2017,21(1),235-246.; 1895896; http://hdl.handle.net/20.500.11897/462396Test; WOS:000394440900022

الإتاحة: https://doi.org/20.500.11897/462396Test
https://doi.org/10.1007/s11030-016-9709-4Test
https://hdl.handle.net/20.500.11897/462396Test

المؤلفون: He, Chong, Wu, Yiran, Lai, Yongquan, Cai, Zongwei, Liu, Ying, Lai, Luhua

المساهمون: Lai, LH (reprint author), Peking Univ, BNLMS, State Key Lab Struct Chem Unstable & Stable Speci, Beijing 100871, Peoples R China., Peking Univ, BNLMS, State Key Lab Struct Chem Unstable & Stable Speci, Beijing 100871, Peoples R China., Peking Univ, Peking Tsinghua Ctr Life Sci, Coll Chem & Mol Engn, Beijing 100871, Peoples R China., Peking Univ, Ctr Theoret Biol, Beijing 100871, Peoples R China., Hong Kong Baptist Univ, Dept Chem, Hong Kong, Hong Kong, Peoples R China.

المصدر: SCI

مصطلحات موضوعية: PROSTAGLANDIN E-2 SYNTHASE-1, MECHANISM-BASED INACTIVATION, HUMAN WHOLE-BLOOD, DEFICIENT MICE, POLYMORPHONUCLEAR LEUKOCYTES, 5-LIPOXYGENASE 5-LOX, CELL-PROLIFERATION, TUMOR-ANGIOGENESIS, DUAL INHIBITORS, DRUG DESIGN

العلاقة: MOLECULAR BIOSYSTEMS.2012,8,(5),1585-1594.; 890702; http://hdl.handle.net/20.500.11897/150985Test; WOS:000302368600023

الإتاحة: https://doi.org/20.500.11897/150985Test
https://doi.org/10.1039/c2mb05503aTest
https://hdl.handle.net/20.500.11897/150985Test