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المؤلفون: Na Jiao, Zi-Huan Yang, Lixin Zhu, Richele Bettencourt, Dingfeng Wu, Sa Fang, Ruixin Zhu, Ping Lan, Rohit Loomba
المصدر: Physiol Genomics
مصطلحات موضوعية: 0301 basic medicine, Male, Physiology, medicine.drug_class, Disease, Biology, Gut flora, Genome, digestive system, Pathogenesis, Bile Acids and Salts, 03 medical and health sciences, 0302 clinical medicine, Non-alcoholic Fatty Liver Disease, Nonalcoholic fatty liver disease, Coenzyme A Ligases, Genetics, medicine, Humans, Precision Medicine, Gene, Bile acid, Fatty liver, Hydroxysteroid Dehydrogenases, Reproducibility of Results, Middle Aged, medicine.disease, biology.organism_classification, Precision medicine, 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific), digestive system diseases, Gut microbiome, Gastrointestinal Microbiome, 030104 developmental biology, Metagenomics, Case-Control Studies, Immunology, 030211 gastroenterology & hepatology, Female, Research Article
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::929309c5fd24cd8744fbcb5abb2c3928Test
https://pubmed.ncbi.nlm.nih.gov/34151600Test -
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المؤلفون: Seiji Mori, Hiroaki Mitsuizumi
المصدر: The journal of physical chemistry. B. 125(19)
مصطلحات موضوعية: Male, endocrine system, Stereochemistry, Dehydrogenase, Molecular Dynamics Simulation, 010402 general chemistry, 01 natural sciences, Catalysis, QM/MM, chemistry.chemical_compound, 0103 physical sciences, Materials Chemistry, Non-covalent interactions, Humans, Physical and Theoretical Chemistry, chemistry.chemical_classification, 010304 chemical physics, biology, Nicotinamide, Hydride, Hydroxysteroid Dehydrogenases, Substrate (chemistry), Active site, Dihydrotestosterone, 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific), 0104 chemical sciences, Surfaces, Coatings and Films, chemistry, Pharmaceutical Preparations, biology.protein, Nicotinamide adenine dinucleotide phosphate
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cc6f6fde8f1262325f980a0a8e687f0Test
https://pubmed.ncbi.nlm.nih.gov/33955223Test -
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المؤلفون: Kateřina, Žížalová, Marek, Vecka, Libor, Vítek, Martin, Leníček
المصدر: PLoS ONE, Vol 15, Iss 7, p e0236372 (2020)
PLoS ONEمصطلحات موضوعية: Research Validity, Physiology, Science, Research and Analysis Methods, Biochemistry, Rodents, Bile Acids and Salts, Model Organisms, Diagnostic Medicine, Medicine and Health Sciences, Animals, Humans, Bile, Dehydrogenases, Enzyme Assays, Mammals, Cholestasis, Organisms, Reproducibility of Results, Biology and Life Sciences, Proteins, Eukaryota, Animal Models, Research Assessment, 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific), Clinical Laboratory Sciences, Rats, Enzymes, Body Fluids, Clinical Laboratories, Bioassays and Physiological Analysis, Experimental Organism Systems, Vertebrates, Amniotes, Enzymology, Animal Studies, Medicine, Anatomy, Biochemical Analysis, Oxidoreductases, Research Article
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a4785093985dd6143284dbc911ff84e7Test
https://doaj.org/article/be6666e36c6641dcb4649fb975e15027Test -
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المؤلفون: Biao Xu, Min Ding, Yue Cui, Mingsong Zhu, Gang Tian, Xiaoqing Zhang, Zhenghu Shi
المصدر: Biosensors and Bioelectronics. 85:563-567
مصطلحات موضوعية: 0301 basic medicine, Biomedical Engineering, Biophysics, Dehydrogenase, Biosensing Techniques, Electrochemical detection, Nicotinamide adenine dinucleotide, 01 natural sciences, Bile Acids and Salts, 03 medical and health sciences, chemistry.chemical_compound, Limit of Detection, Electrochemistry, Humans, Electrodes, chemistry.chemical_classification, Chemistry, 010401 analytical chemistry, Significant difference, Electrochemical Techniques, Equipment Design, General Medicine, 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific), NAD, Serum samples, 0104 chemical sciences, 030104 developmental biology, Enzyme, Biochemistry, Lower cost, NAD+ kinase, Biotechnology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b602e77d44424dc70483d2b4fe02bbc5Test
https://doi.org/10.1016/j.bios.2016.05.055Test -
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المؤلفون: María Florencia Rossetti, Rocio Schumacher, Jorgelina Varayoud, Ayelen L. Gomez, Gisela Paola Lazzarino, Jorge G. Ramos
مصطلحات موضوعية: 0301 basic medicine, Aldosterone synthase, medicine.medical_specialty, 030209 endocrinology & metabolism, Biochemistry, Hippocampus, SENSORY ENRICHMENT, Epigenesis, Genetic, Running, Ciencias Biológicas, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, 3-Oxo-5-alpha-Steroid 4-Dehydrogenase, Internal medicine, Gene expression, medicine, Animals, Cytochrome P-450 CYP11B2, Epigenetics, Rats, Wistar, Promoter Regions, Genetic, Molecular Biology, Gene, DNA METHYLATION, Environmental enrichment, biology, Cytochrome P450, Steroid 17-alpha-Hydroxylase, STEROIDOGENIC ENZYMES, Methylation, DNA Methylation, Bioquímica y Biología Molecular, 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific), Housing, Animal, MOTOR ENRICHMENT, Biosynthetic Pathways, Rats, Up-Regulation, 030104 developmental biology, DNA methylation, biology.protein, HIPPOCAMPUS, Female, Photic Stimulation, CIENCIAS NATURALES Y EXACTAS
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bed3f86a529a855ecef60c8ffc799af8Test
https://www.sciencedirect.com/science/article/pii/S0303720719300371?via=ihubTest -
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المؤلفون: Bo Zhang, Fernand Labrie, Dao-Wei Zhu, Peng Shang, Xiao-Qiang Wang, Sheng-Xiang Lin, Jean-François Thériault, Xiao-Jian Hu
المصدر: Biochemical Journal. 473:1037-1046
مصطلحات موضوعية: 0301 basic medicine, Down-Regulation, Dehydrogenase, Plasma protein binding, Epiandrosterone, Biology, Biochemistry, Protein Structure, Secondary, 03 medical and health sciences, 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific), 0302 clinical medicine, X-Ray Diffraction, Oxidoreductase, Humans, Binding site, Molecular Biology, chemistry.chemical_classification, Binding Sites, Cell growth, Dihydrotestosterone, Cell Biology, Growth Inhibitors, 030104 developmental biology, Enzyme, chemistry, 030220 oncology & carcinogenesis, MCF-7 Cells, Crystallization, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d1dcdf559700f223e9c84a66918ec1cTest
https://doi.org/10.1042/bcj20160083Test -
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المؤلفون: Gao Xiufeng, Liting Ma, Chen Jianmin, Li Yongsheng, Lin Hong
المصدر: Protein Expression and Purification. 115:102-108
مصطلحات موضوعية: endocrine system, Molecular Sequence Data, Dehydrogenase, Biology, medicine.disease_cause, Cofactor, Bacterial Proteins, Affinity chromatography, Metals, Heavy, Enzyme Stability, medicine, Amino Acid Sequence, Escherichia coli, Thermostability, chemistry.chemical_classification, 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific), Molecular biology, Recombinant Proteins, Enzyme assay, Open reading frame, Enzyme, chemistry, Biochemistry, Pseudomonas aeruginosa, biology.protein, Sequence Alignment, Biotechnology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dd48a2f235b17a400b761ce09f28fa2Test
https://doi.org/10.1016/j.pep.2015.07.006Test -
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المؤلفون: Alexander Tobias Teichmann, Runlan Wan, Siwen Tao, Xi Kong, Youyou Chen, Frank Heinrich Wieland, Youzhe Yang
المصدر: The Journal of Steroid Biochemistry and Molecular Biology. 198:105527
مصطلحات موضوعية: 0301 basic medicine, AKR1C1, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, Administration, Oral, Biochemistry, Formestane, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Chlorocebus aethiops, medicine, Animals, Humans, Protein Isoforms, Aromatase, 20-Hydroxysteroid Dehydrogenases, Molecular Biology, chemistry.chemical_classification, Aldo-keto reductase, biology, Chemistry, Aldo-Keto Reductase Family 1 Member C3, Androstenedione, Hydroxysteroid Dehydrogenases, Biological activity, Cell Biology, 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific), Recombinant Proteins, Molecular Docking Simulation, Kinetics, 030104 developmental biology, Enzyme, Cell culture, 030220 oncology & carcinogenesis, COS Cells, Solvents, biology.protein, Molecular Medicine, Steroids, Oxidoreductases, Protein Binding, Steroidal Aromatase Inhibitor, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9666380c5bb9b509fa5c0812ee60e9fTest
https://doi.org/10.1016/j.jsbmb.2019.105527Test -
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المؤلفون: Satomi, Inaba, Ayako, Shiota, Takuya, Yoshida, Masayuki, Oda
المصدر: Analytical biochemistry. 574
مصطلحات موضوعية: Nitrogen Isotopes, Protein Conformation, Tyrosine, 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific), NAD, Nuclear Magnetic Resonance, Biomolecular, Protein Binding, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::d8152664d7ca3f77c53903dcc50bc97fTest
https://pubmed.ncbi.nlm.nih.gov/30910701Test -
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المصدر: Applied and Environmental Microbiology. 84
مصطلحات موضوعية: 0301 basic medicine, medicine.drug_class, 030106 microbiology, medicine.disease_cause, Applied Microbiology and Biotechnology, 03 medical and health sciences, Bacterial Proteins, medicine, Humans, Enzymology and Protein Engineering, Gene, Escherichia coli, Peptide sequence, Ecology, Bile acid, Chemistry, Hydroxysteroid Dehydrogenases, 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific), G protein-coupled bile acid receptor, Gastrointestinal Microbiome, Actinobacteria, 030104 developmental biology, Biochemistry, Genes, Bacterial, Multigene Family, Farnesoid X receptor, Metagenomics, Heterologous expression, Food Science, Biotechnology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1d2e0ca8ad65dc9a8452e6950ca023eTest
https://doi.org/10.1128/aem.02475-17Test