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1دورية أكاديمية
المؤلفون: Robustelli, Paul, Ibanez de Opakua, Alain, Campbell-Bezat, Cecily, Giordanetto, Fabrizio, Becker, Stefan, Zweckstetter, Markus, Pan, Albert C, Shaw, David E
المصدر: Journal of the American Chemical Society 144(6), 2501 - 2510 (2022). doi:10.1021/jacs.1c07591
مصطلحات موضوعية: info:eu-repo/classification/ddc/540, 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: analogs & derivatives, 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: chemistry, 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: metabolism, Amino Acid Sequence, Hydrogen Bonding, Intrinsically Disordered Proteins: chemistry, Intrinsically Disordered Proteins: metabolism, Ligands, Molecular Conformation, Molecular Dynamics Simulation, Protein Binding, Small Molecule Libraries: chemistry, Small Molecule Libraries: metabolism, alpha-Synuclein: metabolism, Intrinsically Disordered Proteins, Small Molecule Libraries, alpha-Synuclein, 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine, fasudil
جغرافية الموضوع: DE
العلاقة: info:eu-repo/semantics/altIdentifier/pmid/pmid:35130691; info:eu-repo/semantics/altIdentifier/issn/1520-5126; info:eu-repo/semantics/altIdentifier/issn/1943-2984; info:eu-repo/semantics/altIdentifier/issn/0002-7863; https://pub.dzne.de/record/163399Test; https://pub.dzne.de/search?p=id:%22DZNE-2022-00161%22Test
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2دورية أكاديمية
المؤلفون: Asokan, Nandini, Daetwyler, Stephan, Brand, Michael, Bornhäuser, Martin, Bernas, Stefanie, Schmied, Christopher, Vogler, Steffen, Lambert, Katrin, Wobus, Manja, Wermke, Martin, Kempermann, Gerd, Huisken, Jan
المصدر: Scientific reports 10(1), 13254 (2020). doi:10.1038/s41598-020-69956-2
مصطلحات موضوعية: info:eu-repo/classification/ddc/600, 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: administration & dosage, 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: analogs & derivatives, 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: therapeutic use, Animals, Breast Neoplasms: diagnostic imaging, Breast Neoplasms: drug therapy, Cell Line, Tumor, Cell Tracking, Female, Leukemia: diagnostic imaging, Leukemia: drug therapy, Microscopy, Neoplasm Invasiveness, Neoplasm Metastasis: diagnostic imaging, Neoplasm Metastasis: drug therapy, Neoplasm Transplantation, Time-Lapse Imaging, Zebrafish, 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine, fasudil
جغرافية الموضوع: DE
العلاقة: info:eu-repo/semantics/altIdentifier/issn/2045-2322; info:eu-repo/semantics/altIdentifier/pmid/pmid:32764590; https://pub.dzne.de/record/154306Test; https://pub.dzne.de/search?p=id:%22DZNE-2021-00160%22Test
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3دورية أكاديمية
المؤلفون: Jonas, Jean-Christophe, Li, Guodong, Palmer, M, Weller, U, Wollheim, Claes B.
المساهمون: Université de Genève - Faculté de Médecine, UCL - MD/FSIO - Département de physiologie et pharmacologie
المصدر: The Biochemical journal, Vol. 301 ( Pt 2), p. 523-9 (1994)
مصطلحات موضوعية: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine - analogs & derivatives, Adenosine Triphosphate - pharmacology, Isoquinolines - pharmacology, Kinetics, Piperazines - pharmacology, Staphylococcus aureus, Type C Phospholipases - pharmacology, Calcium - pharmacology, Calcium-Calmodulin-Dependent Protein Kinases - antagonists & inhibitors, Cell Line, Cell Membrane Permeability, Guanosine 5'-O-(3-Thiotriphosphate) - pharmacology, Guanosine Triphosphate - pharmacology, Guanylyl Imidodiphosphate - pharmacology, Insulin - secretion, Permeabilized cells, Insulin secretion, GTP, Calcium, ATP, Staphylococcus aureus alpha-toxin
العلاقة: info:eu-repo/grantAgreement/FRS-FNRS/Mandat d'aspirant/; boreal:76117; http://hdl.handle.net/2078Test.1/76117; info:pmid/8042998; urn:ISSN:0264-6021
الإتاحة: http://hdl.handle.net/2078Test.1/76117
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4دورية أكاديمية
المؤلفون: Tatenhorst, Lars, Eckermann, Katrin, Outeiro, Tiago F, Zweckstetter, Markus, Lingor, Paul, Dambeck, Vivian, Fonseca-Ornelas, Luis, Walle, Hagen, Lopes da Fonseca, Tomás, Koch, Jan C, Becker, Stefan, Tönges, Lars, Bähr, Mathias
المصدر: Acta Neuropathologica Communications 4(1), 39 (2016). doi:10.1186/s40478-016-0310-y
مصطلحات موضوعية: info:eu-repo/classification/ddc/610, 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: analogs & derivatives, 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: pharmacology, 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: therapeutic use, Amides: pharmacology, Amides: therapeutic use, Animals, Brain: drug effects, Brain: metabolism, Brain: pathology, Carrier Proteins: metabolism, Cell Line, Tumor, Disease Models, Animal, Enzyme Inhibitors: pharmacology, Enzyme Inhibitors: therapeutic use, Gene Expression Regulation: drug effects, Gene Expression Regulation: genetics, Humans, Mice, Transgenic, Mutation: genetics, Nerve Tissue Proteins: metabolism, Parkinson Disease: drug therapy, Parkinson Disease: genetics, Parkinson Disease: metabolism, Protein Aggregates: drug effects, Protein Aggregates: genetics, Protein Kinase Inhibitors: pharmacology
جغرافية الموضوع: DE
العلاقة: info:eu-repo/semantics/altIdentifier/issn/2051-5960; info:eu-repo/semantics/altIdentifier/pmid/pmid:27101974; https://pub.dzne.de/record/138528Test; https://pub.dzne.de/search?p=id:%22DZNE-2020-04850%22Test
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5دورية أكاديمية
المؤلفون: Martinsen, Anneloes, Baeyens, Nicolas, Yerna, Xavier, Morel, Nicole
المصدر: Cell calcium, 52 (6
مصطلحات موضوعية: Sciences bio-médicales et agricoles, 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine -- analogs & derivatives -- pharmacology, Amides -- pharmacology, Animals, Aorta -- cytology -- drug effects -- enzymology, Azepines -- pharmacology, Calcium -- metabolism, Cells, Cultured, Down-Regulation -- drug effects, Enzyme Inhibitors -- pharmacology, In Vitro Techniques, Male, Muscle, Smooth, Vascular -- drug effects -- enzymology, Myosin-Light-Chain Kinase -- antagonists & inhibitors -- metabolism, Naphthalenes -- pharmacology, Phosphorylation, Pyridines -- pharmacology, Rats, Wistar, Signal Transduction -- drug effects, Vasopressins -- pharmacology, rho-Associated Kinases -- antagonists & inhibitors -- metabolism, rhoA GTP-Binding Protein -- metabolism
وصف الملف: 1 full-text file(s): application/pdf
العلاقة: uri/info:doi/10.1016/j.ceca.2012.07.002; uri/info:pii/S0143-4160(12)00139-X; uri/info:pmid/22883550; https://dipot.ulb.ac.be/dspace/bitstream/2013/259989Test/1/Elsevier_243616.pdf; http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/259989Test
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6دورية أكاديمية
المؤلفون: Mak, JC, Man, RYK, Chan, CKY, Vanhoutte, PM
مصطلحات موضوعية: Isometric Contraction - drug effects, Male, Pyridines - chemistry - pharmacology, Species Specificity, Rats, rho-Associated Kinases - antagonists & inhibitors - biosynthesis, Inbred SHR, Hypertension - drug therapy - enzymology - physiopathology, Inbred WKY, Endothelium, Vascular - drug effects - enzymology - physiology, Dose-Response Relationship, Drug, Antihypertensive Agents - chemistry - pharmacology, Aorta, Thoracic - drug effects - enzymology - physiopathology, 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine - analogs & derivatives - chemistry - pharmacology, Amides - chemistry - pharmacology, Animals, Blotting, Western, Vasoconstriction - drug effects
العلاقة: Journal of Pharmacology and Experimental Therapeutics; http://www.scopus.com/mlt/select.url?eid=2-s2.0-65649115407&selection=ref&src=s&origin=recordpageTest; Journal of Pharmacology And Experimental Therapeutics, 2009, v. 329 n. 2, p. 820-826; 8153556; 826; 157370; WOS:000265444000045; http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0022-3565&volume=329&spage=820&epage=826&date=2009&atitle=Rho+kinase+inhibitors+prevent+endothelium-dependent+contractions+in+the+rat+aortaTest; eid_2-s2.0-65649115407; 820; http://hdl.handle.net/10722/59230Test; 329
الإتاحة: https://doi.org/10.1124/jpet.108.148247Test
http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0022-3565&volume=329&spage=820&epage=826&date=2009&atitle=Rho+kinase+inhibitors+prevent+endothelium-dependent+contractions+in+the+rat+aortaTest
http://hdl.handle.net/10722/59230Test -
7دورية أكاديمية
المؤلفون: Pochet, Stéphanie, Garcia-Marcos, Mikel, Seil, Michèle, Otto, Anne, Marino, Aida, Dehaye, Jean-Paul
المصدر: Cellular signalling, 19 (10
مصطلحات موضوعية: Sciences bio-médicales et agricoles, 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine -- analogs & derivatives, 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine -- pharmacology, Adenosine Triphosphate -- analogs & derivatives, Adenosine Triphosphate -- antagonists & inhibitors, Adenosine Triphosphate -- pharmacology, Animals, Biological Transport, Calcium -- metabolism, Carbachol -- pharmacology, Ethidium -- metabolism, Interleukin-1beta -- metabolism, Mice, Knockout, Phospholipases A2 -- metabolism, Receptors, Purinergic P2 -- genetics, Purinergic P2 -- physiology, Saliva -- chemistry, Submandibular Gland -- cytology, Submandibular Gland -- drug effects, Submandibular Gland -- metabolism, Exocrine glands, IL-1β, KO mice, P2X7 receptors, Purinergic, Saliva
وصف الملف: 1 full-text file(s): application/pdf
العلاقة: uri/info:doi/10.1016/j.cellsig.2007.06.012; uri/info:pii/S0898-6568(07)00189-1; uri/info:pmid/17651941; uri/info:scp/34548432100; uri/info:ulb-repo/set/1; https://dipot.ulb.ac.be/dspace/bitstream/2013/68177Test/1/Elsevier_45255.pdf; http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/68177Test
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8دورية أكاديمية
المؤلفون: Pochet, Stéphanie, Tandel, Séverine, Querriere, Stéphanie, Tré-Hardy, Marie, Garcia-Marcos, Mikel, De Lorenzi, Manuela, Vandenbranden, Michel, Marino, Aida, Devleeschouwer, Michel, Dehaye, Jean-Paul
المصدر: Molecular pharmacology, 69 (6
مصطلحات موضوعية: Sciences bio-médicales et agricoles, 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine -- analogs & derivatives, 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine -- pharmacology, Adenosine Triphosphate -- metabolism, Adenosine Triphosphate -- pharmacology, Animals, Antimicrobial Cationic Peptides -- antagonists & inhibitors, Antimicrobial Cationic Peptides -- metabolism, Antimicrobial Cationic Peptides -- pharmacology, Calcium -- metabolism, Cations, Divalent -- pharmacology, Cell Membrane -- drug effects, Enzyme Inhibitors -- pharmacology, Group IV Phospholipases A2, Magnesium -- pharmacology, Male, Membrane Fluidity -- drug effects, Mice, Inbred C57BL, Muscarinic Agonists -- metabolism, Muscarinic Agonists -- pharmacology, Phospholipases A -- drug effects, Receptors, Purinergic P2 -- agonists, Salivary Glands -- drug effects, Submandibular Gland -- drug effects
وصف الملف: 1 full-text file(s): application/pdf
العلاقة: uri/info:doi/10.1124/mol.105.021444; uri/info:pii/mol.105.021444; uri/info:pmid/16514052; uri/info:scp/33745165297; https://dipot.ulb.ac.be/dspace/bitstream/2013/57069Test/1/Pochet_et_al_2006_Mol_Pharmacol_69_2037.pdf; http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/57069Test
الإتاحة: http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/57069Test
https://dipot.ulb.ac.be/dspace/bitstream/2013/57069Test/1/Pochet_et_al_2006_Mol_Pharmacol_69_2037.pdf -
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المساهمون: Université de Genève - Faculté de Médecine, UCL - MD/FSIO - Département de physiologie et pharmacologie
المصدر: The Biochemical journal, Vol. 301 ( Pt 2), p. 523-9 (1994)
مصطلحات موضوعية: Cell Membrane Permeability, GTP', medicine.medical_treatment, Stimulation, Calcium-Calmodulin-Dependent Protein Kinases - antagonists & inhibitors, Biochemistry, Piperazines, Adenosine Triphosphate, Desensitization (telecommunications), 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine, Insulin Secretion, Guanosine 5'-O-(3-Thiotriphosphate) - pharmacology, Staphylococcus aureus alpha-toxin, Insulin, Guanosine Triphosphate - pharmacology, Guanylyl Imidodiphosphate, Kinase, Piperazines - pharmacology, Insulin secretion, Adenosine Triphosphate - pharmacology, Permeabilized cells, Guanosine Triphosphate, Research Article, medicine.medical_specialty, Staphylococcus aureus, chemistry.chemical_element, Biology, Calcium, Guanylyl Imidodiphosphate - pharmacology, Exocytosis, Cell Line, Insulin - secretion, Internal medicine, medicine, 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine - analogs & derivatives, Secretion, Molecular Biology, Cell Biology, Isoquinolines, ATP, Kinetics, Endocrinology, Calcium - pharmacology, chemistry, Isoquinolines - pharmacology, Guanosine 5'-O-(3-Thiotriphosphate), Type C Phospholipases, Calcium-Calmodulin-Dependent Protein Kinases, Type C Phospholipases - pharmacology, GTP
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcb4330258b8311e3f3b32e439954951Test
https://europepmc.org/articles/PMC1137112Test/ -
10مورد إلكتروني
المصدر: Cell calcium, 52 (6
مصطلحات الفهرس: Sciences bio-médicales et agricoles, 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine -- analogs & derivatives -- pharmacology, Amides -- pharmacology, Animals, Aorta -- cytology -- drug effects -- enzymology, Azepines -- pharmacology, Calcium -- metabolism, Cells, Cultured, Down-Regulation -- drug effects, Enzyme Inhibitors -- pharmacology, In Vitro Techniques, Male, Muscle, Smooth, Vascular -- drug effects -- enzymology, Myosin-Light-Chain Kinase -- antagonists & inhibitors -- metabolism, Naphthalenes -- pharmacology, Phosphorylation, Pyridines -- pharmacology, Rats, Rats, Wistar, Signal Transduction -- drug effects, Vasopressins -- pharmacology, rho-Associated Kinases -- antagonists & inhibitors -- metabolism, rhoA GTP-Binding Protein -- metabolism, info:eu-repo/semantics/article, info:ulb-repo/semantics/articlePeerReview, info:ulb-repo/semantics/openurl/article
