يعرض 1 - 10 نتائج من 28 نتيجة بحث عن '"0000-0001-5597-8127"', وقت الاستعلام: 0.96s تنقيح النتائج
  1. 1
    Towards Enantiomerically Pure Unnatural α-Amino Acids via Photoredox Catalytic 1,4-Additions to a Chiral Dehydroalanine

    المؤلفون: Oroz, Paula, Navo, Claudio D., Avenoza, Alberto, Busto, Jesús H., Corzana, Francisco, Jiménez-Osés, Gonzalo, Peregrina, Jesús M., 0000-0003-0161-412X, 0000-0003-4403-4790, 0000-0001-5597-8127, 0000-0003-0105-4337, 0000-0003-3778-7065

    المصدر: The Journal of Organic Chemistry. 87:14308-14318

    مصطلحات موضوعية: Organic Chemistry, Stereoisomerism, Amino Acids, Catalysis, Carbon

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::090eacfc5929b6046ef0613ba114b79dTest
    https://doi.org/10.1021/acs.joc.2c01774Test


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  2. 2
    Selective Inhibition of Bruton's Tyrosine Kinase by a Designed Covalent Ligand Leads to Potent Therapeutic Efficacy in Blood Cancers Relative to Clinically Used Inhibitors

    المؤلفون: Sousa, Bárbara B., de Almeida, Cátia Rebelo, Barahona, Ana F., Lopes, Raquel, Martins-Logrado, Ana, Cavaco, Marco, Neves, Vera, Carvalho, Luís A.R., Labaõ-Almeida, Carlos, Coelho, Ana R., Bento, Marta Leal, Lopes, Ricardo M.R.M., Oliveira, Bruno L., Castanho, Miguel A.R.B., Neumeister, Peter, Deutsch, Alexander, Vladimer, Gregory I., Krall, Nikolaus, Joaõ, Cristina, Corzana, Francisco, Seixas, Joaõ D., Fior, Rita, Bernardes, Gonçalo J.L., 0000-0002-0938-9038, 0000-0002-2989-7208, 0000-0001-7891-7562, 0000-0003-4205-7585, 0000-0001-5597-8127, 0000-0001-6594-8917

    المساهمون: Cavaco, Marco [0000-0002-0938-9038], Neves, Vera [0000-0002-2989-7208], Castanho, Miguel ARB [0000-0001-7891-7562], Vladimer, Gregory I [0000-0003-4205-7585], Corzana, Francisco [0000-0001-5597-8127], Bernardes, Gonçalo JL [0000-0001-6594-8917], Apollo - University of Cambridge Repository

    مصطلحات موضوعية: Pharmacology, Lymphoma, 32 Biomedical and Clinical Sciences, Hematology, 3211 Oncology and Carcinogenesis, Orphan Drug, Rare Diseases, BTK, 5.1 Pharmaceuticals, hematological cancers, covalent inhibitor, antitumor activity, Pharmacology (medical), preclinical studies, 5 Development of treatments and therapeutic interventions, Cancer

    وصف الملف: application/zip; application/pdf; text/xml

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfe3f9b0697dca6740a74f3e7bf89647Test
    https://www.repository.cam.ac.uk/handle/1810/343251Test


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  3. 3
    Single Mutation on Trastuzumab Modulates the Stability of Antibody-Drug Conjugates Built Using Acetal-Based Linkers and Thiol-Maleimide Chemistry

    المؤلفون: Ferhati, Xhenti, Jiménez-Moreno, Ester, Hoyt, Emily A., Salluce, Giulia, Cabeza-Cabrerizo, Mar, Navo, Claudio D., Compañón, Ismael, Akkapeddi, Padma, Matos, Maria J., Salaverri, Noelia, Garrido, Pablo, Martínez, Alfredo, Laserna, Víctor, Murray, Thomas V., Jiménez-Osés, Gonzalo, Ravn, Peter, Bernardes, Gonçalo J. L., Corzana, Francisco, 0000-0002-5045-433X, 0000-0001-6940-8803, 0000-0002-1615-6822, 0000-0003-0161-412X, 0000-0002-3470-8299, 0000-0002-5960-8569, 0000-0003-4882-4044, 0000-0003-0105-4337, 0000-0001-6594-8917, 0000-0001-5597-8127

    المساهمون: Jiménez-Moreno, Ester [0000-0002-5045-433X], Hoyt, Emily A [0000-0001-6940-8803], Salluce, Giulia [0000-0002-1615-6822], Navo, Claudio D [0000-0003-0161-412X], Matos, Maria J [0000-0002-3470-8299], Garrido, Pablo [0000-0002-5960-8569], Martínez, Alfredo [0000-0003-4882-4044], Jiménez-Osés, Gonzalo [0000-0003-0105-4337], Bernardes, Gonçalo JL [0000-0001-6594-8917], Corzana, Francisco [0000-0001-5597-8127], Apollo - University of Cambridge Repository, Repositório da Universidade de Lisboa, Lopes Bernardes, Goncalo [0000-0001-6594-8917]

    المصدر: RIUR. Repositorio Institucional de la Universidad de La Rioja
    instname

    مصطلحات موضوعية: Maleimides, Colloid and Surface Chemistry, Acetals, Immunoconjugates, Mutation, Antineoplastic Agents, General Chemistry, Sulfhydryl Compounds, Trastuzumab, Biochemistry, Catalysis

    وصف الملف: application/pdf; application/octet-stream

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::602082ac290726aecf4a1ef02e832266Test


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  4. 4
    Binding-driven reactivity attenuation enables NMR identification of selective drug candidates for nucleic acid targets

    المؤلفون: Díaz-Casado, Laura, Santana, Andrés G., Gómez-Pinto, Irene, Villacampa, Alejandro, Corzana, Francisco, Jiménez-Barbero, Jesús, González, Carlos, Asensio, Juan Luis, 0000-0003-0333-8624, 0000-0003-3568-7714, 0000-0001-7514-9991, 0000-0001-5597-8127, 0000-0001-5421-8513, 0000-0001-8796-1282, 0000-0001-7536-5221

    المساهمون: Ministerio de Economía y Competitividad (España), European Commission, Ministerio de Ciencia, Innovación y Universidades (España), Díaz-Casado, Laura, Santana, Andrés G., Villacampa, Alejandro, Corzana, Francisco, Jiménez-Barbero, Jesús, González, Carlos, Asensio, Juan Luis

    المصدر: Communications Chemistry. 5

    مصطلحات موضوعية: Materials Chemistry, Environmental Chemistry, General Chemistry, Biochemistry

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4707eea3eadf77ad15acf8ab478a731Test
    https://doi.org/10.1038/s42004-022-00755-8Test


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  5. 5
    Platform for Orthogonal N-Cysteine-Specific Protein Modification Enabled by Cyclopropenone Reagents

    المؤلفون: Istrate, Alena, Geeson, Michael B., Navo, Claudio D., Sousa, Barbara B., Marques, Marta C., Taylor, Ross J., Journeaux, Toby, Oehler, Sebastian R., Mortensen, Michael R., Deery, Michael J., Bond, Andrew D., Corzana, Francisco, Jiménez-Osés, Gonzalo, Bernardes, Gonçalo J. L., 0000-0002-9228-7947, 0000-0003-0161-412X, 0000-0003-4561-1828, 0000-0002-1744-0489, 0000-0001-5597-8127, 0000-0003-0105-4337, 0000-0001-6594-8917

    المساهمون: Geeson, Michael B [0000-0002-9228-7947], Navo, Claudio D [0000-0003-0161-412X], Journeaux, Toby [0000-0003-4561-1828], Bond, Andrew D [0000-0002-1744-0489], Corzana, Francisco [0000-0001-5597-8127], Jiménez-Osés, Gonzalo [0000-0003-0105-4337], Bernardes, Gonçalo JL [0000-0001-6594-8917], Apollo - University of Cambridge Repository

    المصدر: RIUR. Repositorio Institucional de la Universidad de La Rioja
    instname
    Journal of the American Chemical Society, 144 (23)

    مصطلحات موضوعية: Cyclopropanes, Colloid and Surface Chemistry, Proteins, Indicators and Reagents, Cysteine, General Chemistry, Biochemistry, Catalysis

    وصف الملف: application/pdf; application/application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaa740cfe85dd76a13a1f924d2b40d43Test
    https://investigacion.unirioja.es/documentos/62c9e7a6a405bc00e417fb39Test


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  6. 6
    Lipoyl-Based Antagonists of Transient Receptor Potential Cation A (TRPA1) Downregulate Osteosarcoma Cell Migration and Expression of Pro-Inflammatory Cytokines

    المؤلفون: Francesconi, Oscar, Corzana, Francisco, Kontogianni, Georgia-Ioanna, Pesciullesi, Giorgio, Gualdani, Roberta, Supuran, Claudiu T., Angeli, Andrea, Kavasi, Rafaela Maria, Chatzinikolaidou, Maria, Nativi, Cristina, 0000-0002-6155-4926, 0000-0001-5597-8127, 0000-0003-3617-4953, 0000-0003-4262-0323, 0000-0002-1470-7192, 0000-0002-6312-3230

    المساهمون: UCL - SSS/IONS/CEMO - Pôle Cellulaire et moléculaire

    المصدر: ACS Pharmacology and Translational Science, Vol. 5, no. 11, p. 1119-1127 (2022)

    مصطلحات موضوعية: Pharmacology, neuropathic pain, osteosarcoma, lipoyl derivatives, TRPA1 channel, Pharmacology (medical)

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb9dab0186a59b63675a298fb4538d4aTest
    https://pubmed.ncbi.nlm.nih.gov/36407953Test


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  7. 7
    Structural and mechanistic insights into the cleavage of clustered O-glycan patches-containing glycoproteins by mucinases of the human gut

    المؤلفون: Taleb, Víctor, Liao, Qinghua, Narimatsu, Yoshiki, García-García, Ana, Compañón, Ismael, Borges, Rafael Junqueira, González-Ramírez, Andrés Manuel, Corzana, Francisco, Clausen, Henrik, Rovira, Carme, Hurtado-Guerrero, Ramon, 0000-0003-1428-5695, 0000-0003-3791-2997, 0000-0001-6049-8806, 0000-0002-5838-0857, 0000-0001-5597-8127, 0000-0002-0915-5055, 0000-0003-1477-5010, 0000-0002-3122-9401

    المصدر: RIUR. Repositorio Institucional de la Universidad de La Rioja
    instname
    Zaguán. Repositorio Digital de la Universidad de Zaragoza
    Taleb, V, Liao, Q, Narimatsu, Y, García-García, A, Compañón, I, Borges, R J, González-Ramírez, A M, Corzana, F, Clausen, H, Rovira, C & Hurtado-Guerrero, R 2022, ' Structural and mechanistic insights into the cleavage of clustered O-glycan patches-containing glycoproteins by mucinases of the human gut ', Nature Communications, vol. 13, no. 1, 4324 . https://doi.org/10.1038/s41467-022-32021-9Test

    مصطلحات موضوعية: Multidisciplinary, Carbohydrates, Glycopeptides, Mucins, General Physics and Astronomy, General Chemistry, General Biochemistry, Genetics and Molecular Biology, Intestines, Polysaccharides, Republic of Korea, Humans, Sugars, Glycoproteins, Polysaccharide-Lyases

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed4e0539b8ea6dc97c6efec179f956a2Test
    https://investigacion.unirioja.es/documentos/62f80c9f9162cc4ea7f1fcb9Test


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  8. 8
    Structural basis for the synthesis of the core 1 structure by C1GalT1

    المؤلفون: González-Ramírez, Andrés Manuel, Grosso, Ana Sofia, Yang, Zhang, Compañón, Ismael, Coelho, Helena, Narimatsu, Yoshiki, Clausen, Henrik, Marcelo, Filipa, Corzana, Francisco, Hurtado-Guerrero, Ramon, 0000-0002-5838-0857, 0000-0002-4756-5813, 0000-0003-1428-5695, 0000-0002-0915-5055, 0000-0001-5597-8127, 0000-0002-3122-9401

    المساهمون: UCIBIO - Applied Molecular Biosciences Unit, DQ - Departamento de Química

    المصدر: RIUR. Repositorio Institucional de la Universidad de La Rioja
    instname
    Zaguán. Repositorio Digital de la Universidad de Zaragoza
    González-Ramírez, A M, Grosso, A S, Yang, Z, Compañón, I, Coelho, H, Narimatsu, Y, Clausen, H, Marcelo, F, Corzana, F & Hurtado-Guerrero, R 2022, ' Structural basis for the synthesis of the core 1 structure by C1GalT1 ', Nature Communications, vol. 13, no. 1, 2398 . https://doi.org/10.1038/s41467-022-29833-0Test

    مصطلحات موضوعية: Multidisciplinary, Glycosylation, Chemistry(all), Biochemistry, Genetics and Molecular Biology(all), Glycopeptides, Mucins, General Physics and Astronomy, General Chemistry, Physics and Astronomy(all), Crystallography, X-Ray, General Biochemistry, Genetics and Molecular Biology, carbohydrates (lipids), lipids (amino acids, peptides, and proteins), Amino Acid Sequence

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be0a22fe46c5990d3b306b6ba2e334a3Test
    https://investigacion.unirioja.es/documentos/628009a43333e458234bb7e1Test


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  9. 9
    Observation of the Unbiased Conformers of Putative DNA-Scaffold Ribosugars

    المؤلفون: Calabrese, Camilla, Uriarte, Iciar, Insausti, Aran, Vallejo-López, Montserrat, Basterretxea, Francisco J., Cochrane, Stephen A., Davis, Benjamin G., Corzana, Francisco, Cocinero, Emilio J., 0000-0003-4299-2098, 0000-0002-6239-6915, 0000-0002-5056-407X, 0000-0001-5597-8127, 0000-0001-7632-3728

    المصدر: Calabrese, C, Uriarte, I, Vallejo-Lopez, M, Basterretxea, F, Cochrane, S, Davis, B, Corzana, F & Cocinero, E J 2020, ' Observation of the Unbiased Conformers of Putative DNA-Scaffold Ribosugars ', ACS Central Science, vol. 6, no. 2, pp. 293-303 . https://doi.org/10.1021/acscentsci.9b01277Test
    RIUR. Repositorio Institucional de la Universidad de La Rioja
    instname
    ACS Central Science
    ACS Central Science, Vol 6, Iss 2, Pp 293-303 (2020)

    مصطلحات موضوعية: 010405 organic chemistry, Stereochemistry, Chemistry, Hydrogen bond, General Chemical Engineering, Solvation, Context (language use), General Chemistry, 010402 general chemistry, 01 natural sciences, 0104 chemical sciences, chemistry.chemical_compound, Nucleophile, Intramolecular force, Molecule, QD1-999, Conformational isomerism, DNA, Research Article

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e52d2d140c1e28e4d628b40f50b22c77Test
    https://doi.org/10.1021/acscentsci.9b01277Test


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  10. 10
    Structural basis for substrate specificity and catalysis of α1,6-fucosyltransferase

    المؤلفون: García-García, Ana, Ceballos-Laita, Laura, Serna, Sonia, Artschwager, Raik, Reichardt, Niels C., Corzana, Francisco, Hurtado-Guerrero, Ramon, 0000-0002-7223-1719, 0000-0001-5597-8127, 0000-0002-3122-9401

    المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
    RIUR. Repositorio Institucional de la Universidad de La Rioja
    instname
    Nature Communications
    García-García, A, Ceballos-Laita, L, Serna, S, Artschwager, R, Reichardt, N C, Corzana, F & Hurtado-Guerrero, R 2020, ' Structural basis for substrate specificity and catalysis of α1,6-fucosyltransferase ', Nature Communications, vol. 11, no. 1, 973 . https://doi.org/10.1038/s41467-020-14794-zTest
    Zaguán. Repositorio Digital de la Universidad de Zaragoza
    Consejo Superior de Investigaciones Científicas (CSIC)

    مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Glycan, Glycosylation, Stereochemistry, Science, General Physics and Astronomy, 010402 general chemistry, Crystallography, X-Ray, 01 natural sciences, Guanosine Diphosphate, General Biochemistry, Genetics and Molecular Biology, SH3 domain, Fucose, Article, Substrate Specificity, src Homology Domains, 03 medical and health sciences, chemistry.chemical_compound, Residue (chemistry), Polysaccharides, Catalytic Domain, Humans, Binding site, lcsh:Science, Multidisciplinary, biology, Molecular biophysics, General Chemistry, Fucosyltransferases, Microarray Analysis, Recombinant Proteins, 0104 chemical sciences, carbohydrates (lipids), 030104 developmental biology, chemistry, Carbohydrate Sequence, Biocatalysis, biology.protein, lcsh:Q, Glycoconjugates

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d1495af9d69be0cd3837c7b7ba0266cTest
    https://doaj.org/article/6eaef7c9348f45cc8e916ae6a380340aTest


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