نتائج البحث - "ботулинический токсин типа А"

1

دورية أكاديمية

Local injection therapy in the complex treatment of musculoskeletal disorders: principles of application, evidence base, safety ; Локальная инъекционная терапия в комплексном лечении болезней костно-мышечной системы: основные принципы использования, доказательная база, безопасность

المساهمون: Expert advice was performed with the technical support of Rompharm Company., Совет экспертов проведен при техническом содействии Rompharm Company.

المصدر: Modern Rheumatology Journal; Том 17, № 4 (2023); 120-137 ; Современная ревматология; Том 17, № 4 (2023); 120-137 ; 2310-158X ; 1996-7012

مصطلحات موضوعية: радиосиновэктомия, rheumatic diseases, glucocorticoids, hyaluronic acid, platelet-rich plasma, botulinum toxin type A, radiosynovectomy, ревматические заболевания, глюкокортикоиды, гиалуроновая кислота, обогащенная тромбоцитами плазма, ботулинический токсин типа А

وصف الملف: application/pdf

العلاقة: https://mrj.ima-press.net/mrj/article/view/1447/1372Test; Насонов ЕЛ, Яхно НН, Каратеев АЕ и др. Общие принципы лечения скелетно-мышечной боли: междисциплинарный консенсус. Научно-практическая ревматология. 2016;54(3):247-265.; Singh H, Knapik DM, Polce EM, et al. Relative Efficacy of Intra-articular Injections in the Treatment of Knee Osteoarthritis: A Systematic Review and Network Meta-analysis. Am J Sports Med. 2022 Sep;50(11):3140-3148. doi:10.1177/03635465211029659. Epub 2021 Aug 17.; Marcolina A, Vu K, Chien GC. Peripheral Joint Injections. Phys Med Rehabil Clin N Am. 2022 May;33(2):267-306. doi:10.1016/j.pmr.2022.01.005.; Girolimetto N, Macchioni P, Tinazzi I, et al. Ultrasound Effectiveness of Steroid Injection for hand Psoriatic Dactylitis: Results from a Longitudinal Observational Study. Rheumatol Ther. 2021 Dec;8(4):1809-1826. doi:10.1007/s40744-021-00383-z. Epub 2021 Oct 15.; Tumpaj T, Potocnik Tumpaj V, Albano D, Snoj Z. Ultrasound-guided carpal tunnel injections. Radiol Oncol. 2022 Feb 11;56(1): 14-22. doi:10.2478/raon-2022-0004.; Aicale R, Bisaccia RD, Oliviero A, et al. Current pharmacological approaches to the treatment of tendinopathy. Expert Opin Pharmacother. 2020 Aug;21(12):1467-1477. doi:10.1080/14656566.2020.1763306. Epub 2020 Jun 8.; Bannuru RR, Vaysbrot EE, Sullivan MC, McAlindon TE. Relative efficacy of hyaluronic acid in comparison with NSAIDs for knee osteoarthritis: a systematic review and meta-analysis. Semin Arthritis Rheum. 2014 Apr;43(5): 593-9. doi:10.1016/j.semarthrit.2013.10.002. Epub 2013 Oct 14.; Uson J, Rodriguez-Garcia SC, Castellanos-Moreira R, et al. EULAR recommendations for intra-articular therapies. Ann Rheum Dis. 2021 Oct;80(10):1299-1305. doi:10.1136/annrheumdis-2021-220266.; Monseau AJ, Nizran PS. Common injections in musculoskeletal medicine. Prim Care. 2013 Dec;40(4):987-1000, ix-x. doi:10.1016/j.pop.2013.08.012. Epub 2013 Sep 24.; Bannuru RR, Osani MC, Vaysbrot EE, et al. OARSI guidelines for the non-surgical management of knee, hip, and polyarticular osteoarthritis. Osteoarthritis Cartilage. 2019 Nov; 27(11):1578-1589. doi:10.1016/j.joca.2019.06.011. Epub 2019 Jul 3.; Kolasinski SL, Neogi T, Hochberg MC, et al. 2019 American College of Rheumatology/ Arthritis Foundation Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee. Arthritis Rheumatol. 2020 Feb; 72(2):220-233. doi:10.1002/art.41142. Epub 2020 Jan 6.; Bruyere O, Honvo G, Veronese N, et al. An updated algorithm recommendation for the management of knee osteoarthritis from the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO). Semin Arthritis Rheum. 2019 Dec;49(3):337-350. doi:10.1016/j.semarthrit.2019.04.008. Epub 2019 Apr 30.; https://cr.minzdrav.gov.ru/recomend/667_1Test; https://cr.minzdrav.gov.ru/schema/666_1#doc_a3Test; Phillips M, Bhandari M, Grant J, et al. A Systematic Review of Current Clinical Practice Guidelines on Intra-articular Hyaluronic Acid, Corticosteroid, and Platelet-Rich Plasma Injection for Knee Osteoarthritis: An International Perspective. Orthop J Sports Med. 2021 Aug 31;9(8):23259671211030272. doi:10.1177/23259671211030272.; Lafrance S, Charron M, Roy JS, et al. Diagnosing, Managing, and Supporting Re-turn to Work of Adults With Rotator Cuff Di-sorders: A Clinical Practice Guideline. J Ort-hop Sports Phys Ther. 2022 Oct;52(10): 647-664. doi:10.2519/jospt.2022.11306. Epub 2022 Jul 26.; Di Filippo L, Vincenzi S, Pennella D, Maselli F. Treatment, Diagnostic Criteria and Variability of Terminology for Lateral Elbow Pain: Findings from an Overview of Systematic Reviews. Healthcare (Basel). 2022 Jun 14; 10(6):1095. doi:10.3390/healthcare10061095.; Lapner P, Alfonso A, Herbert-Davies J, et al; Canadian Shoulder and Elbow Society (CSES). Position statement: nonoperative management of lateral epicondylitis in adults. Can J Surg. 2022 Sep 21;65(5):E625-E629. doi:10.1503/cjs.019221. Print 2022 Sep-Oct.; Lee J, Griepp DW, Burgess CJ, et al. The AAOS 2019 Clinical Practice Guidelines for the Management of Rotator Cuff Injuries Are Unbiased and Incorporate a Diverse Body of Literature. Arthrosc Sports Med Rehabil. 2022 Mar 1;4(2):e559-e565. doi:10.1016/j.asmr.2021.11.017. eCollection 2022 Apr.; Hetland ML, 0stergaard M, Ejbjerg B, et al; CIMESTRA study group. Shortand long-term efficacy of intra-articular injections with beta-methasone as part of a treat-to-target strategy in early rheumatoid arthritis: impact of joint area, repeated injections, MRI findings, anti-CCP, IgM-RF and CRP. Ann Rheum Dis. 2012 Jun;71(6):851-6. doi:10.1136/annrheumdis-2011-200632. Epub 2012 Feb 1.; Foster ZJ, Voss TT, Hatch J, Frimodig A. Corticosteroid Injections for Common Musculoskeletal Conditions. Am Fam Physician. 2015 Oct 15;92(8):694-9.; Lai Q, Cai K, Lin T, et al. Prior Intra-articular Corticosteroid Injection Within 3 Months May Increase the Risk of Deep Infection in Subsequent Joint Arthroplasty: A Meta-analysis. Clin Orthop Relat Res. 2022 May 1;480(5): 971-979. doi:10.1097/CORR.0000000000002055. Epub 2021 Dec 17.; Hunter JA, Blyth TH. A risk-benefit assessment of intra-articular corticosteroids in rheumatic disorders. Drug Saf. 1999 Nov; 21(5):353-65. doi:10.2165/00002018-199921050-00002.; Mohamed M, Patel S, Plavnik K, et al. Retrospective Analysis of Septic Arthritis Caused by Intra-Articular Viscosupplementation and Steroid Injections in a Single Outpatient Center. J Clin Med Res. 2019 Jul;11(7): 480-483. doi:10.14740/jocmr3838.; Holland C, Jaeger L, Smentkowski U, et al. Septic and aseptic complications of corticosteroid injections: an assessment of 278 cases reviewed by expert commissions and mediation boards from 2005 to 2009. Dtsch Arztebl Int. 2012 Jun;109(24):425-30. doi:10.3238/arztebl.2012.0425. Epub 2012 Jun 15.; Charalambous CP, Tryfonidis M, Sadiq S, et al. Septic arthritis following intra-articular steroid injection of the knee — a survey of current practice regarding antiseptic technique used during intra-articular steroid injection of the knee. Clin Rheumatol. 2003 Dec;22(6): 386-90. doi:10.1007/s10067-003-0757-7. Epub 2003 Oct 15.; Lin CY, Huang SC, Tzou SJ, et al. A Positive Correlation between Steroid Injections and Cuff Tendon Tears: A Cohort Study Using a Clinical Database. Int J Environ Res Public Health. 2022 Apr 8;19(8):4520. doi:10.3390/ijerph19084520.; Kampen WU, Boddenberg-Patzold B, Fischer M, et al; EANM Bone & Joint Committee, the Dosimetry Committee, the Oncology & Theranostics Committee. The EANM guideline for radiosynoviorthesis. Eur J Nucl Med Mol Imaging. 2022 Jan;49(2):681-708. doi:10.1007/s00259-021-05541-7. Epub 2021 Oct 20.; Van der Zant FM, Boer RO, Moolenburgh JD, et al. Radiation synovectomy with (90)Yttrium, (186)Rhenium and (169)Erbium: a systematic literature review with meta-analyses. Clin Exp Rheumatol. 2009 Jan-Feb;27(1):130-9.; Kampen WU, Voth M, Pinkert J, Krause A. Therapeutic status of radiosynoviorthesis of the knee with yttrium [90Y] colloid in rheumatoid arthritis and related indications. Rheumatology (Oxford). 2007 Jan;46(1):16-24. doi:10.1093/rheumatology/kel352. Epub 2006 Oct 25.; Hoeber S, Aly AR, Ashworth N, Rajasekaran S. Ultrasound-guided hip joint injections are more accurate than landmark-guided injections: a systematic review and meta-analysis. Br J Sports Med. 2016 Apr;50(7):392-6. doi:10.1136/bjsports-2014-094570. Epub 2015 Jun 10.; Huang Z, Du S, Qi Y, et al. Effectiveness of Ultrasound Guidance on Intraarticular and Periarticular Joint Injections: Systematic Review and Meta-analysis of Randomized Trials. Am J Phys Med Rehabil. 2015 Oct;94(10):775-83. doi:10.1097/PHM.0000000000000260.; Pereira TV, Juni P, Saadat P, et al. Viscosupplementation for knee osteoarthritis: systematic review and meta-analysis. BMJ. 2022 Jul 6;378:e069722. doi:10.1136/bmj-2022-069722.; Gazendam A, Ekhtiari S, Bozzo A, et al. Intra-articular saline injection is as effective as corticosteroids, platelet-rich plasma and hyaluronic acid for hip osteoarthritis pain: a systematic review and network meta-analysis of randomised controlled trials. Br J Sports Med. 2021 Mar;55(5):256-261. doi:10.1136/bjsports-2020-102179. Epub 2020 Aug 22.; Каратеев АЕ, Погожева ЕЮ, Амирджанова ВН и др. «Мне стало лучше» и «мне стало хорошо»: поиск объективного критерия клинического ответа на анальгетическую терапию при ревматических заболеваниях. Современная ревматология. 2020;14(2):90-96. doi:10.14412/1996-7012-2020-2-90-96; Kaplan DJ, Haskel JD, Kirby DJ, et al. The Simplified Science of Corticosteroids for Clinicians.JBJS Rev. 2020 Nov;8(11):e2000038. doi:10.2106/JBJS.RVW.20.00038.; Najm A, Alunno A, Gwinnutt JM, et al. Efficacy of intra-articular corticosteroid injections in knee osteoarthritis: A systematic review and meta-analysis of randomized controlled trials. Joint Bone Spine. 2021 Jul;88(4): 105198. doi:10.1016/j.jbspin.2021.105198. Epub 2021 Apr 24.; Zhong HM, Zhao GF, Lin T, et al. Intra-Articular Steroid Injection for Patients with Hip Osteoarthritis: A Systematic Review and Meta-Analysis. Biomed Res Int.2020 Feb 24; 2020:6320154. doi:10.1155/2020/6320154.; Cushman DM, Ofek E, Syed RH, et al. Comparison of Varying Corticosteroid Type, Dose, and Volume for the Treatment of Pain in Small- and Intermediate-Size Joint Injections: A Narrative Review. PM R. 2019 Jul; 11(7):758-770. doi:10.1016/j.pmrj.2018.09.040. Epub 2019 Jun 5.; Coombes BK, Bisset L, Vicenzino B. Efficacy and safety of corticosteroid injections and other injections for management of tendinopathy: a systematic review of randomised controlled trials. Lancet. 2010 Nov 20; 376(9754):1751-67. doi:10.1016/S0140-6736(10)61160-9. Epub 2010 Oct 21.; Challoumas D, Biddle M, McLean M, Millar NL. Comparison of Treatments for Frozen Shoulder: A Systematic Review and Meta-analysis. JAMA Netw Open. 2020 Dec 1; 3(12):e2029581. doi:10.1001/jamanetworkopen.2020.29581.; Dernis E, Ruyssen-Witrand A, Mouterde G, et al. Use of glucocorticoids in rheumatoid arthritis — pratical modalities of glucocorticoid therapy: recommendations for clinical practice based on data from the literature and expert opinion. Joint Bone Spine. 2010 Oct; 77(5):451-7. doi:10.1016/j.jbspin.2009.12.010. Epub 2010 May 14.; Ramiro S, Nikiphorou E, Sepriano A, et al. ASAS-EULAR recommendations for the management of axial spondyloarthritis: 2022 update. Ann Rheum Dis. 2023 Jan;82(1):19-34. doi:10.1136/ard-2022-223296. Epub 2022 Oct 21.; Gossec L, Baraliakos X, Kerschbaumer A, et al. EULAR recommendations for the management of psoriatic arthritis with pharmacological therapies: 2019 update. Ann Rheum Dis. 2020 Jun;79(6):700-712. doi:10.1136/annrheumdis-2020-217159.; Richette P, Doherty M, Pascual E, et al. 2016 updated EULAR evidence-based recommendations for the management of gout. Ann Rheum Dis. 2017 Jan;76(1):29-42. doi:10.1136/annrheumdis-2016-209707. Epub 2016 Jul 25.; Juni P, Hari R, Rutjes AW, et al. Intra-articular corticosteroid for knee osteoarthritis. Cochrane Database Syst Rev. 2015 Oct 22; (10):CD005328. doi:10.1002/14651858.CD005328.pub3.; Samuels J, Pillinger MH, Jevsevar D, et al. Critical appraisal of intra-articular glucocorticoid injections for symptomatic osteoarthritis of the knee. Osteoarthritis Cartilage. 2021 Jan; 29(1):8-16. doi:10.1016/j.joca.2020.09.001. Epub 2020 Sep 7.; Billesberger LM, Fisher KM, Qadri YJ, Boortz-Marx RL. Procedural Treatments for Knee Osteoarthritis: A Review of Current Injectable Therapies. Pain Res Manag. 2020 Feb 18;2020:3873098. doi:10.1155/2020/3873098. eCollection 2020.; Dean BJ, Lostis E, Oakley T, et al. The risks and benefits of glucocorticoid treatment for tendinopathy: a systematic review of the effects of local glucocorticoid on tendon. Semin Arthritis Rheum. 2014 Feb;43(4):570-6. doi:10.1016/j.semarthrit.2013.08.006. Epub 2013 Sep 26.; Kompel AJ, Roemer FW, Murakami AM, et al. Intra-articular Corticosteroid Injections in the Hip and Knee: Perhaps Not as Safe as We Thought? Radiology. 2019 Dec;293(3): 656-663. doi:10.1148/radiol.2019190341.; Ayub S, Kaur J, Hui M, et al. Efficacy and safety of multiple intra-articular corticosteroid injections for osteoarthritis-a systematic review and meta-analysis of randomized controlled trials and observational studies. Rheumatology (Oxford). 2021 Apr 6;60(4):1629-1639. doi:10.1093/rheumatology/keaa808.; Pereira H, Sousa DA, Cunha A, et al. Hyaluronic Acid. Adv Exp Med Biol. 2018; 1059:137-153. doi:10.1007/978-3-319-76735-2_6.; Oliva F, Marsilio E, Asparago G, et al. The Impact of Hyaluronic Acid on Tendon Physiology and Its Clinical Application in Tendinopathies. Cells. 2021 Nov 9;10(11): 3081. doi:10.3390/cells10113081.; Li C, Cao Z, Li W, et al. A review on the wide range applications of hyaluronic acid as a promising rejuvenating biomacromolecule in the treatments of bone related diseases. Int J Biol Macromol. 2020 Dec 15;165(Pt A):1264-1275. doi:10.1016/j.ijbiomac.2020.09.255. Epub 2020 Oct 8.; Gupta RC, Lall R, Srivastava A, Sinha A. Hyaluronic Acid: Molecular Mechanisms and Therapeutic Trajectory. Front Vet Sci. 2019 Jun 25;6:192. doi:10.3389/fvets.2019.00192. eCollection 2019.; Cooper C, Rannou F, Richette P, et al. Use of Intraarticular Hyaluronic Acid in the Management of Knee Osteoarthritis in Clinical Practice. Arthritis Care Res (Hoboken). 2017 Sep;69(9):1287-1296. doi:10.1002/acr.23204. Epub 2017 Aug 8.; Hummer CD, Angst F, Ngai W, et al. High molecular weight Intraarticular hyaluronic acid for the treatment of knee osteoarthritis: a network meta-analysis. BMC Musculoskelet Disord. 2020 Oct 23;21(1):702. doi:10.1186/s12891-020-03729-w.; Altman R, Lim S, Steen RG, Dasa V. Hyaluronic Acid Injections Are Associated with Delay of Total Knee Replacement Surgery in Patients with Knee Osteoarthritis: Evi-dence from a Large U.S. Health Claims Data-base. PLoS One. 2015 Dec 22;10(12):e0145776. doi:10.1371/journal.pone.0145776. eCollection 2015.; Molloy IB, Holte AJ, Zhao Y, et al. The Effect of Intra-articular Hyaluronic Acid Injections and Payer Coverage on Total Knee Arthroplasty Procedures: Evidence From Large US Claims Database. Arthroplast Today. 2022 Dec 30;19:101080. doi:10.1016/j.artd.2022.101080. eCollection 2023 Feb.; Алексеева ЛИ, Кашеварова НГ, Таскина ЕА и др. Эффективность и безопасность внутрисуставного применения комбинации гиалуроната натрия и хондроитина сульфата при остеоартрите коленного сустава: многоцентровое проспективное исследование. Терапевтический архив. 2020;92(5):46-54.; Migliore A, Gigliucci G, Alekseeva L, et al. Systematic Literature Review and Expert Opinion for the Use of Viscosupplementation with Hyaluronic Acid in Different Localizations of Osteoarthritis. Orthop Res Rev. 2021 Dec 2;13:255-273. doi:10.2147/ORR.S336185. eCollection 2021.; Khan M, Shanmugaraj A, Prada C, et al. The Role of Hyaluronic Acid for Soft Tissue Indications: A Systematic Review and Meta-Analysis. Sports Health. 2023 Jan-Feb;15(1): 86-96. doi:10.1177/19417381211073316. Epub 2022 Feb 3.; Osti L, Buda M, Buono AD, et al. Clinical evidence in the treatment of rotator cuff tears with hyaluronic acid. Muscles Ligaments Tendons J. 2016 Feb 13;5(4):270-5. doi:10.11138/mltj/2015.5.4.270. eCollection 2015 Oct-Dec.; Cohen SA, Brophy RH, Chen AF, et al. Public Interest in Hyaluronic Acid Injections for Knee Osteoarthritis in the United States and Europe: An International Google Trends Analysis. Arthroplast Today. 2022 Nov 2; 18:157-162. doi:10.1016/j.artd.2022.09.003. eCollection 2022 Dec.; Jevsevar DS, Brown GA, Jones DL, et al. The American Academy of Orthopaedic Surgeons evidence-based guideline on: treatment of osteoarthritis of the knee, 2nd edition. J Bone Joint Surg Am. 2013 Oct 16;95(20):1885-6. doi:10.2106/00004623-201310160-00010.; Miller LE, Bhattacharyya S, Parrish WR, et al. Safety of Intra-Articular Hyaluronic Acid for Knee Osteoarthritis: Systematic Re-view and Meta-Analysis of Randomized Trials Involving More than 8,000 Patients. Cartilage. 2021 Dec;13(1_suppl):351S-363S. doi:10.1177/1947603519888783.; Honvo G, Reginster JY, Rannou F, et al. Safety of Intra-articular Hyaluronic Acid Injections in Osteoarthritis: Outcomes of a Systematic Review and Meta-Analysis. Drugs Aging. 2019 Apr;36(Suppl 1):101-127. doi:10.1007/s40266-019-00657-w.; Migliore A, Paoletta M, Moretti A, et al. The perspectives of intra-articular therapy in the management of osteoarthritis. Expert Opin Drug Deliv. 2020 Sep;17(9):1213-1226. doi:10.1080/17425247.2020.1783234. Epub 2020 Jun 22.; Pelletier JP, Raynauld JP, Abram F, et al. Exploring determinants predicting response to intra-articular hyaluronic acid treatment in symptomatic knee osteoarthritis: 9-year follow-up data from the Osteoarthritis Initiative. Arthritis Res Ther. 2018 Mar 1;20(1):40. doi:10.1186/s13075-018-1538-7.; Vincent P, Lucas de Couville T, Thomas T. Intra-Articular Hyaluronic Acid for Knee Osteoarthritis: A Postmarket, Open-Label, Long-Term Historical Control Study with Analysis Detailed per Krellgren-Lawrence Radiologic Osteoarthritis Scale Grade. Curr Ther Res Clin Exp. 2020 Feb 26;92:100575. doi:10.1016/j.curtheres.2020.100575. eCollection 2020.; Deseyne N, Conrozier T, Lellouche H, et al. Hip Inflammation MRI Scoring System (HIMRISS) to predict response to hyaluronic acid injection in hip osteoarthritis. Joint Bone Spine. 2018 Jul;85(4):475-480. doi:10.1016/j.jbspin.2017.08.004. Epub 2017 Sep 8.; Conrozier T, Mathieu P, Schott AM, et al. Factors predicting long-term efficacy of Hylan GF-20 viscosupplementation in knee osteoarthritis. Joint Bone Spine. 2003 Mar;70(2): 128-33. doi:10.1016/s1297-319x(03)00005-8.; Wang CC, Wang CT, Tsai KL, et al. Effect of ultrasound-detected synovitis on therapeutic efficacy of hyaluronic acid injection for symptomatic knee osteoarthritis. Rheumatology (Oxford). 2021 Oct 2;60(10):4486-4494. doi:10.1093/rheumatology/keab020.; Chalidis B, Givissis P, Papadopoulos P, Pitsilos C. Molecular and Biologic Effects of Platelet-Rich Plasma (PRP) in Ligament and Tendon Healing and Regeneration: A Syste-matic Review. Int J Mol Sci. 2023 Feb 1;24(3): 2744. doi:10.3390/ijms24032744.; Liang Y, Li J, Wang Y, et al. Platelet Rich Plasma in the Repair of Articular Cartilage Injury: A Narrative Review. Cartilage. 2022 Jul-Sep;13(3):19476035221118419. doi:10.1177/19476035221118419.; Sax OC, Chen Z, Mont MA, Delanois RE. The Efficacy of Platelet-Rich Plasma for the Treatment of Knee Osteoarthritis Symptoms and Structural Changes: A Systematic Review and Meta-Analysis. J Arthroplasty. 2022 Nov;37(11):2282-2290.e2. doi:10.1016/j.arth.2022.05.014. Epub 2022 May 7.; McLarnon M, Heron N. Intra-articular platelet-rich plasma injections versus intra-articular corticosteroid injections for symptomatic management of knee osteoarthritis: systematic review and meta-analysis. BMC Musculoskelet Disord. 2021 Jun 16;22(1):550. doi:10.1186/s12891-021-04308-3.; Belk JW, Houck DA, Littlefield CP, et al. Platelet-Rich Plasma Versus Hyaluronic Acid for Hip Osteoarthritis Yields Similarly Beneficial Short-Term Clinical Outcomes: A Systematic Review and Meta-analysis of Level I and II Randomized Controlled Trials. Arthroscopy. 2022 Jun;38(6):2035-2046. doi:10.1016/j.arthro.2021.11.005. Epub 2021 Nov 14.; Dai W, Yan W, Leng X, et al. Efficacy of Platelet-Rich Plasma Versus Placebo in the Treatment of Tendinopathy: A Meta-analysis of Randomized Controlled Trials. Clin J Sport Med. 2023 Jan 1;33(1):69-77. doi:10.1097/JSM.0000000000000961.; Moraes VY, Lenza M, Tamaoki MJ, et al. Platelet-rich therapies for musculoskeletal soft tissue injuries. Cochrane Database Syst Rev. 2014 Apr 29;2014(4):CD010071. doi:10.1002/14651858.CD010071.pub3.; Lin MT, Wei KC, Wu CH. Effectiveness of Platelet-Rich Plasma Injection in Rotator Cuff Tendinopathy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Diagnostics (Basel). 2020 Mar 28; 10(4):189. doi:10.3390/diagnostics10040189.; Chen XT, Fang W, Jones IA, et al. The Efficacy of Platelet-Rich Plasma for Improving Pain and Function in Lateral Epicondylitis: A Systematic Review and Meta-analysis with Risk-of-Bias Assessment. Arthroscopy. 2021 Sep; 37(9):2937-2952. doi:10.1016/j.arthro.2021.04.061. Epub 2021 May 5.; Нестеренко ВА, Каратеев АЕ, Макаров МА и др. Сравнение эффективности субакромиального введения обогащенной тромбоцитами плазмы и гиалуроновой кислоты при хронической боли в области плеча, вызванной поражением сухожилий мышц вращающей манжеты плеча, по данным 6-месячного открытого клинического исследования. Научно-практическая ревматология. 2020;58(5):570-576.; Vargel I, Tuncel A, Baysal N, et al. Autologous Adipose-Derived Tissue Stromal Vascular Fraction (AD-tSVF) for Knee Osteoarthritis. Int J Mol Sci. 2022 Nov 4;23(21): 13517. doi:10.3390/ijms232113517.; Imam MA, Holton J, Horriat S, et al. A systematic review of the concept and clinical applications of bone marrow aspirate concentrate in tendon pathology. SICOT J. 2017;3:58. doi:10.1051/sicotj/2017039. Epub 2017 Oct 9.; Гатиатулина ЕР, Мантурова НЕ, Димов ГП и др. Стромально-васкулярная фракция жировой ткани: механизм действия, перспективы и риски местного применения. Пластическая хирургия и эстетическая медицина. 2019;(2):43-48.; Kim KI, Kim MS, Kim JH. Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials. Am J Sports Med. 2023 Mar;51(3):837-848. doi:10.1177/03635465211053893. Epub 2022 Jan 12.; Shoukrie SI, Venugopal S, Dhanoa RK, et al. Safety and Efficacy of Injecting Mesenchymal Stem Cells Into a Human Knee Joint To Treat Osteoarthritis: A Systematic Review. Cureus. 2022 May 8;14(5):e24823. doi:10.7759/cureus.24823. eCollection 2022 May.; Jin L, Yang G, Men X, et al. Intra-articular Injection of Mesenchymal Stem Cells After High Tibial Osteotomy: A Systematic Re-view and Meta-analysis. Orthop J Sports Med. 2022 Nov 23;10(11):23259671221133784. doi:10.1177/23259671221133784. eCollection 2022 Nov.; Heidari N, Slevin M, Zeinolabediny Y, et al. Comparison of the Effect of MFAT and MFAT + PRP on Treatment of Hip Osteo-arthritis: An Observational, Intention-to-Treat Study at One Year. J Clin Med. 2022 Feb 17; 11(4):1056. doi:10.3390/jcm11041056.; Natali S, Screpis D, Romeo M, et al. Is intra-articular injection of autologous micro-fragmented adipose tissue effective in hip osteoarthritis? A three year follow-up. Int Ort-hop. 2023 Jun;47(6):1487-1492. doi:10.1007/s00264-022-05611-x. Epub 2022 Oct 28.; Senesi L, De Francesco F, Marchesini A, et al. Efficacy of Adipose-Derived Mesenchymal Stem Cells and Stromal Vascular Fraction Alone and Combined to Biomaterials in Tendinopathy or Tendon Injury: Systematic Review of Current Concepts. Medicina (Kaunas). 2023 Jan 31;59(2):273. doi:10.3390/medicina59020273.; Bono OJ, Jenkin B, Forlizzi J, et al. Evidence for Utilization of Injectable Biologic Augmentation in Primary Rotator Cuff Repair: A Systematic Review of Data From 2010 to 2022. Orthop J Sports Med. 2023 Feb 3;11(2): 23259671221150037. doi:10.1177/23259671221150037. eCollection 2023 Feb.; Lee SY, Kim W, Lim C, Chung SG. Treatment of Lateral Epicondylosis by Using Allogeneic Adipose-Derived Mesenchymal Stem Cells: A Pilot Study. Stem Cells. 2015 Oct; 33(10):2995-3005. doi:10.1002/stem.2110. Epub 2015 Aug 6.; De Jongh FW, Schaeffers AWMA, Kooreman ZE, et al. Botulinum toxin A treatment in facial palsy synkinesis: a systematic review and meta-analysis. Eur Arch Otorhinolaryngol. 2023 Apr;280(4):1581-1592. doi:10.1007/s00405-022-07796-8. Epub 2022 Dec 22.; Doan TN, Kuo MY, Chou LW. Efficacy and Optimal Dose of Botulinum Toxin A in Post-Stroke Lower Extremity Spasticity: A Systematic Review and Meta-Analysis. Toxins (Basel). 2021 Jun 18;13(6):428. doi:10.3390/toxins13060428.; Mei L, Fengqun M, Zhengyao Z, et al. Efficacy and safety of different drug treatments in patients with spinal-cord injury-related neuropathic pain: a network meta-analysis. Spinal Cord. 2022 Nov;60(11):943-953. doi:10.1038/s41393-022-00804-y. Epub 2022 Apr 25.; Yunfeng G, Fei L, Junbo L, et al. An indirect comparison meta-analysis of noninvasive intravesical instillation and intravesical injection of botulinum toxin-A in bladder disorders. Int Urol Nephrol. 2022 Mar;54(3): 479-491. doi:10.1007/s11255-022-03107-6. Epub 2022 Jan 19.; Al-Moraissi EA, Conti PCR, Alyahya A, et al. The hierarchy of different treatments for myogenous temporomandibular disorders: a systematic review and network meta-analysis of randomized clinical trials. Oral Maxillofac Surg. 2022 Dec;26(4):519-533. doi:10.1007/s10006-021-01009-y.; Kumar R. Therapeutic use of botulinum toxin in pain treatment. Neuronal Signal. 2018 Aug 31;2(3):NS20180058. doi:10.1042/NS20180058. eCollection 2018 Sep.; Battista S, Buzzatti L, Gandolfi M, et al. The Use of Botulinum Toxin A as an Adjunctive Therapy in the Management of Chronic Musculoskeletal Pain: A Systematic Review with Meta-Analysis. Toxins (Basel). 2021 Sep 10;13(9):640. doi:10.3390/toxins13090640.; Zhai S, Huang B, Yu K. The efficacy and safety of Botulinum Toxin Type A in painful knee osteoarthritis: a systematic review and meta-analysis. J Int Med Res. 2020 Apr;48(4): 300060519895868. doi:10.1177/0300060519895868. Epub 2019 Dec 29.; Courseau M, Salle PV, Ranoux D, et al. Efficacy of Intra-Articular Botulinum Toxin in Osteoarticular Joint Pain: A Meta-Analysis of Randomized Controlled Trials. Clin J Pain. 2018 Apr;34(4):383-389. doi:10.1097/AJP.0000000000000538.; Wang C, Zhao J, Gao F, et al. The efficacy and safety of intra-articular botulinum toxin type A injection for knee osteoarthritis: A meta-analysis of randomized controlled trials. Toxicon. 2023 Mar 1;224:107026. doi:10.1016/j.toxicon.2023.107026. Epub 2023 Jan 11.; Hsu PC, Wu WT, Han DS, Chang KV. Comparative Effectiveness of Botulinum Toxin Injection for Chronic Shoulder Pain: A Meta-Analysis of Randomized Controlled Trials. Toxins (Basel). 2020 Apr 12;12(4):251. doi:10.3390/toxins12040251.; Балабанова РМ, Олюнин ЮА, Лила АМ. Радиосиновэктомия — альтернатива хирургической синовэктомии у ревматологических больных с рецидивирующими артритами. РМЖ. Медицинское обозрение. 2019;4(1):17-19.; Van der Zant FM, Knol RJ, Broos WA. Radiosynoviorthesis: almost seventy years of experience but still somewhat fameless. Q J Nucl Med Mol Imaging. 2022 Dec;66(4): 293-303. doi:10.23736/S1824-4785.22.03470-7. Epub 2022 Jun 16.; Rodriguez-Merchan EC. Radiosynovectomy in haemophilia. Blood Rev. 2019 May;35: 1-6. doi:10.1016/j.blre.2019.01.002. Epub 2019 Jan 25.; Rodriguez-Merchan EC, De la Corte-Rodriguez H, Jimenez-Yuste V. Radiosynovectomy in haemophilia: long-term results of 500 procedures performed in a 38-year period. Thromb Res. 2014 Nov;134(5):985-90. doi:10.1016/j.thromres.2014.08.023. Epub 2014 Sep 6.; Rabago D, Reeves KD, Doherty MP, Fleck M. Prolotherapy for Musculoskeletal Pain and Disability in Low- and Middle-In-come Countries. Phys Med Rehabil Clin N Am. 2019 Nov;30(4):775-786. doi:10.1016/j.pmr.2019.07.003. Epub 2019 Aug 22.; Chen YW, Lin YN, Chen HC, et al. Effectiveness, Compliance, and Safety of Dextrose Prolotherapy for Knee Osteoarthritis: A Meta-Analysis and Metaregression of Randomized Controlled Trials. Clin Rehabil. 2022 Jun;36(6):740-752. doi:10.1177/02692155221086213. Epub 2022 Mar 8.; Zhu M, Rabago D, Chung VC, et al. Effects of Hypertonic Dextrose Injection (Prolotherapy) in Lateral Elbow Tendinosis: A Systematic Review and Meta-analysis. Arch Phys Med Rehabil. 2022 Nov;103(11):2209-2218. doi:10.1016/j.apmr.2022.01.166. Epub 2022 Feb 28.; Lai WF, Yoon CH, Chiang MT, et al. The effectiveness of dextrose prolotherapy in plantar fasciitis: A systemic review and meta-analysis. Medicine (Baltimore). 2021 Dec 23; 100(51):e28216. doi:10.1097/MD.0000000000028216.; Catapano M, Zhang K, Mittal N, et al. Effectiveness of Dextrose Prolotherapy for Rotator Cuff Tendinopathy: A Systematic Review. PM R. 2020 Mar;12(3):288-300. doi:10.1002/pmrj.12268. Epub 2019 Dec 4.; Rezvani Ghomi E, Nourbakhsh N, Akbari Kenari M, et al. Collagen-based biomaterials for biomedical applications. J Biomed Mater Res B Appl Biomater. 2021 Dec;109(12): 1986-1999. doi:10.1002/jbm.b.34881.; Honvo G, Lengele L, Charles A, et al. Role of Collagen Derivatives in Osteoarthritis and Cartilage Repair: A Systematic Scoping Review With Evidence Mapping. Rheumatol Ther. 2020 Dec;7(4):703-740. doi:10.1007/s40744-020-00240-5. Epub 2020 Oct 17.; Tarantino D, Mottola R, Palermi S, et al. Intra-Articular Collagen Injections for Osteoarthritis: A Narrative Review. Int J Environ Res Public Health. 2023 Mar 1;20(5):4390. doi:10.3390/ijerph20054390.; Corrado B, Bonini I, Chirico VA, et al. Ultrasound-guided collagen injections in the treatment of supraspinatus tendinopathy: a case series pilot study. J Biol Regul Homeost Agents. 2020 May-Jun;34(3 Suppl. 2):33-39.; Godek P, Szczepanowska-Wolowiec B, Golicki D. Collagen and platelet-rich plasma in partial-thickness rotator cuff injuries. Friends or only indifferent neighbours? Randomised controlled trial. BMC Musculoskelet Disord. 2022 Dec 20;23(1):1109. doi:10.1186/s12891-022-06089-9.; Henriksen M, Overgaard A, Hartkopp A, Bliddal H. Intra-articular 2.5% polyacrylamide hydrogel for the treatment of knee osteoarthritis: an observational proof-of-concept cohort study. Clin Exp Rheumatol. 2018 Nov-Dec;36(6):1082-1085. Epub 2018 Jul 18.; Загородний НВ, Страхов МА. Клиническое использование в лечении суставных болевых синдромов синтетического вископротеза Нолтрекс. Opinion leader, 2019;(7-2):24-32.; Кузнецов ВИ. Результаты применения полиакриламидного геля нолтрексин у пациентов с различной стадией гонартроза в амбулаторной практике. Медицинский алфавит. 2021;(33):22-29.; Yilmaz E. The evaluation of the effectiveness of intraarticular steroid, tenoxicam, and combined steroid-tenoxicam injections in the treatment of patients with knee osteoarthritis. Clin Rheumatol. 2019 Nov;38(11):3243-3252. doi:10.1007/s10067-019-04641-y. Epub 2019 Jun 26.; Bellamy JL, Goff BJ, Sayeed SA. Economic Impact of Ketorolac vs Corticosteroid Intra-Articular Knee Injections for Osteoarthritis: A Randomized, Double-Blind, Prospective Study. J Arthroplasty. 2016 Sep;31(9 Suppl): 293-7. doi:10.1016/j.arth.2016.05.015. Epub 2016 May 18.; Park KD, Kim TK, Bae BW, et al. Ultrasound guided intra-articular ketorolac versus corticosteroid injection in osteoarthritis of the hip: a retrospective comparative study. Skeletal Radiol. 2015 Sep;44(9):1333-40. doi:10.1007/s00256-015-2174-9. Epub 2015 Jun 3.; Aksakal M, Ermutlu C, Ozkaya G, Ozkan Y. Lornoxicam injection is inferior to betamethasone in the treatment of subacromial impingement syndrome: A prospective randomized study of functional outcomes. Orthopade. 2017 Feb;46(2):179-185. doi:10.1007/s00132-016-3302-5.; Kim YB, Lee WS, Won JS. The effects of a single-dose subacromial injection of a nonsteroidal anti-inflammatory drug in geriatric patients with subacromial impingement syndrome: a randomized double-blind study. Clin Shoulder Elb. 2021 Mar;24(1):4-8. doi:10.5397/cise.2021.00052. Epub 2021 Mar 2.; Karthikeyan S, Kwong HT, Upadhyay PK, et al. A double-blind randomised controlled study comparing subacromial injection of tenoxicam or methylprednisolone in patients with subacromial impingement. J Bone Joint Surg Br.2010 Jan;92(1):77-82. doi:10.1302/0301-620X.92B1.22137.; Lin MT, Chiang CF, Wu CH, et al. Comparative Effectiveness of Injection Therapies in Rotator Cuff Tendinopathy: A Systematic Review, Pairwise and Network Meta-analysis of Randomized Controlled Trials. Arch Phys Med Rehabil. 2019 Feb;100(2):336-349.e15. doi:10.1016/j.apmr.2018.06.028. Epub 2018 Aug 2.; Sun Y, Chen J, Li H, et al. Steroid Injection and Nonsteroidal Anti-inflammatory Agents for Shoulder Pain: A PRISMA Systematic Review and Meta-Analysis of Randomized Controlled Trials. Medicine (Baltimore). 2015 Dec;94(50):e2216. doi:10.1097/MD.0000000000002216.; Leow MQH, Zheng Q, Shi L, et al. Nonsteroidal anti-inflammatory drugs (NSAIDs) for trigger finger. Cochrane Database Syst Rev. 2021 Apr 14;4(4):CD012789. doi:10.1002/14651858.CD012789.pub2.; Euppayo T, Punyapornwithaya V, Chomdej S, et al. Effects of hyaluronic acid combined with anti-inflammatory drugs compared with hyaluronic acid alone, in clinical trials and experiments in osteoarthritis: a systematic review and meta-analysis. BMC Musculoskelet Disord.2017 Sep 6;18(1):387. doi:10.1186/s12891-017-1743-6.; Zhi F, Cai F, Zhang W, et al. Clinical efficacy of different shoulder joint drug injections for rotator cuff injuries: A network meta-analysis. Medicine (Baltimore). 2022 Sep 30;101(39): e30659. doi:10.1097/MD.0000000000030659.; Zhao J, Huang H, Liang G, et al. Effects and safety of the combination of platelet-rich plasma (PRP) and hyaluronic acid (HA) in the treatment of knee osteoarthritis: a systematic review and meta-analysis. BMC Musculoskelet Disord. 2020 Apr 11;21(1):224. doi:10.1186/s12891-020-03262-w.; Karasavvidis T, Totlis T, Gilat R, Cole BJ. Platelet-Rich Plasma Combined With Hyaluronic Acid Improves Pain and Function Compared With Hyaluronic Acid Alone in Knee Osteoarthritis: A Systematic Review and Meta-analysis. Arthroscopy. 2021 Apr;37(4): 1277-1287.e1. doi:10.1016/j.arthro.2020.11.052. Epub 2020 Dec 3.; Albano D, Gitto S, Serpi F, et al. Ultra-sound-guided Musculoskeletal Interventional Procedures Around the Hip: A Practical Guide. J Ultrason. 2023 Feb 28;23(92):15-22. doi:10.15557/JoU.2023.0003. eCollection 2023 Jan.; Tortora S, Messina C, Gitto S, et al. Ultrasound-guided musculoskeletal interventional procedures around the shoulder. J Ultrason. 2021 Jun 7;21(85):e162-e168. doi:10.15557/JoU.2021.0026. Epub 2021 Jun 18.; Blaine T, Moskowitz R, Udell J, et al. Treatment of persistent shoulder pain with sodium hyaluronate: a randomized, controlled trial. A multicenter study. J Bone Joint Surg Am. 2008 May;90(5):970-9. doi:10.2106/JBJS.F.01116.; Poliwoda S, Noor N, Mousa B, et al. A comprehensive review of intraarticular knee injection therapy, geniculate injections, and peripheral nerve stimulation for knee pain in clinical practice. Orthop Rev (Pavia). 2022 Oct 13;14(4):38676. doi:10.52965/001c.38676. eCollection 2022.; Han YH, Kim KH, Abdi S, Kim TK. Stem cell therapy in pain medicine. Korean J Pain. 2019 Oct 1;32(4):245-255. doi:10.3344/kjp.2019.32.4.245.; Wu T, Song HX, Dong Y, et al. Intra-articular injections of botulinum toxin a for refractory joint pain: a systematic review and meta-analysis. Clin Rehabil. 2017 Apr;31(4): 435-443. doi:10.1177/0269215516644951.; Xie HM, Guo TT, Sun X, et al. Effectiveness of Botulinum Toxin A in Treatment of Hemiplegic Shoulder Pain: A Systematic Review and Meta-analysis. Arch Phys Med Rehabil. 2021 Sep;102(9):1775-1787. doi:10.1016/j.apmr.2020.12.010. Epub 2021 Jan 14.; Лила АМ, Алексеева ЛИ, Таскина ЕА и др. Резолюция консенсуса экспертов Российской Федерации по диагностике и лечению остеоартрита для врачей первичного звена. Терапия. 2022;(5):119-128.; Klein R, Becker EW, Berg PA, Bernau A. Immunomodulatory properties of rumalon, a glycosaminoglycan peptide complex, in patients with osteoarthritis: activation of T helper cell type 2 cytokines and antigen-specific IgG4 antigen-specific igG4 antibodies. J Rheumatol. 2000 Feb;27(2):448-54.; Dean D, Muniz O, Rodriquez I, et al. Amelioration of lapine osteoarthritis by treatment with glycosaminoglycan-peptide association complex (Rumalon). Arthritis Rheum. 1991 Mar;34(3):304-13. doi:10.1002/art.1780340308.; Vignon E, Martin A, Mathieu P, et al. Study of the effect of a glycosaminoglycan-peptide complex on the degradative enzyme activities in human osteoarthritic cartilage. Clin Rheumatol. 1990 Sep;9(3):383-8.; Bouakka M, Loyau G, Bocquet J. Effect of a glycosaminoglycan-peptide complex on the biosynthesis of protoglycans in articular chondrocytes treated with interleukin-1. Curr Ther Res. 1988;43:588-599.; Annefeld M, Erne B. The mode of action of a glycosaminoglycan-peptide-complex (Rumalon) on articular cartilage of the rat in vivo. Clin Rheumatol. 1987 Sep;6(3):340-9.; Алексеева ЛИ, Карякин АН, Смирнов АВ, Беневоленская ЛИ. Применение Румалона при гонартрозе. Терапевтический архив. 1997;(5):64-66.; Каратеев АЕ. Гликозаминогликан-пептидный комплекс при лечении остеоартрита коленного и тазобедренного суставов: из прошлого в будущее. Научно-практическая ревматология. 2020;58(1):91-96.; Каратеев АЕ, Алексеева ЛИ, Погожева ЕЮ и др. Эффективность комбинированного применения гликозаминогликан-пептидного комплекса для внутримышечного введения и перорального диацереина при остеоартрите. Терапевтический архив. 2021;93(5):587-593.; Алексеева ЛИ, Лила АМ, Шарапова ЕП и др. Многоцентровое проспективное исследование эффективности и безопасности гликозаминогликан-пептидного комплекса в комбинации с диацереином у пациентов с остеоартритом коленных суставов. Терапия. 2022;(2):6-18.; https://mrj.ima-press.net/mrj/article/view/1447Test