المؤلفون: S. V. Popov, N. V. Naryzhnaya, M. A. Sirotina, L. N. Maslov, A. V. Mukhomedzyanov, B. K. Kurbatov, A. S. Gorbunov, M. Kilin, A. V. Krylatov, Yu. K. Podeksenov, V. N. Azev, G. Z. Sufianova, M. S. Khlestkina, С. B. Попов, Н. В. Нарыжная, М. А. Сиротина, Л. Н. Маслов, А. В. Мухомедзянов, Б. К. Курбатов, А. С. Горбунов, М. Килин, А. В. Крылатов, Ю. К. Подоксенов, В. Н. Азев, Г. З. Суфианова, М. С. Хлесткина

المساهمون: The work was supported by the Russian Science Foundation, Grant No. 22-15-00048. The section “Synthetic analogues of apelins” is supported by the state assignment 122020300042-4., Обзорная статья выполнена при поддержке Российского научного фонда, грант № 22-1500048. Раздел «Синтетические аналоги апелинов» поддержан государственным заданием 122020300042-4.

المصدر: The Siberian Journal of Clinical and Experimental Medicine; Том 38, № 4 (2023); 29-39 ; Сибирский журнал клинической и экспериментальной медицины; Том 38, № 4 (2023); 29-39 ; 2713-265X ; 2713-2927

مصطلحات موضوعية: легкие, ischemia/reperfusion, brain, heart, kidney, lung, ишемия/реперфузия, головной мозг, сердце, почки

وصف الملف: application/pdf

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Chem. 2022;65(1):531–551.; https://www.sibjcem.ru/jour/article/view/2048Test

الإتاحة: https://doi.org/10.29001/2073-8552-2023-38-4-29-39Test
https://doi.org/10.1002/ccd.29524Test
https://doi.org/10.1136/bmjopen-2022-067579Test
https://doi.org/10.1016/0378-1119Test(93)90495-o
https://doi.org/10.1006/bbrc.1998.9489Test
https://doi.org/10.1016/j.devcel.2013.11.002Test
https://doi.org/10.1371/journal.pone.0093473Test
https://doi.org/10.1074/jbc.M115Test
https://doi.org/10.1016/j.acthis.2018.01.007Test
https://doi.org/10.1161/01.CIR.0000091235.94914.75Test

المؤلفون: N. V. Naryzhnaya, I. A. Derkachev, B. K. Kurbatov, M. A. Sirotina, M. Kilin, L. N. Maslov, Н. В. Нарыжная, И. А. Деркачев, Б. К. Курбатов, М. А. Сиротина, М. Килин, Л. Н. Маслов

المساهمون: Работа выполнена при поддержке Российского научного фонда, грант № 22-15-00048. Исследование механизмов формирования артериальной гипертензии при МетС выполнено в рамках государственного задания 122020300042-4. В работе было использовано оборудование Центра коллективного пользования «Медицинская геномика» ФГБНУ «Томский национальный исследовательский медицинский центр Российской академии наук».

المصدر: Acta Biomedica Scientifica; Том 9, № 1 (2024); 222-232 ; 2587-9596 ; 2541-9420

مصطلحات موضوعية: PPARα, infarction, adaptation to hypoxia, metabolic syndrome, metformin, инфаркт, адаптация к гипоксии, метаболический синдром, метформин

وصف الملف: application/pdf

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المؤلفون: A. V. Mukhomedzyanov, S. V. Popov, N. V. Naryzhnaya, M. А. Sirotina, L. N. Maslov, B. K. Kurbatov, A. S. Gorbunov, M. Kilin, A. Kan, A. V. Krylatov, Yu. K. Podoksenov, V. N. Azev, T. V. Lasukova, G. Z. Sufianova, M. S. Khlestkina, А. В. Мухомедзянов, С. В. Попов, Н. В. Нарыжная, М. А. Сиротина, Л. Н. Маслов, Б. К. Курбатов, А. С. Горбунов, М. Килин, А. Кан, А. В. Крылатов, Ю. К. Подоксёнов, В. Н. Азев, Т. В. Ласукова, Г. З. Суфианова, М. С. Хлёсткина

المساهمون: Тhe article was prepared with the financial support of the Russian Science Foundation, grant MMP (23-65-10017). The introduction to the article was prepared with the support of the state assignment 122020300042-4, Статья подготовлена при финансовой поддержке Российского Научного Фонда (грант 23-65-10017). Введение к статье подготовлено при поддержке государственного задания 122020300042-4

المصدر: The Siberian Journal of Clinical and Experimental Medicine; Том 39, № 1 (2024); 11-17 ; Сибирский журнал клинической и экспериментальной медицины; Том 39, № 1 (2024); 11-17 ; 2713-265X ; 2713-2927

مصطلحات موضوعية: MPT-пора, reperfusion, myocardial infarction, opioid receptors, kinases, K ATP channels, MPT pore, реперфузия, инфаркт миокарда, опиоидные рецепторы, киназы, К АТФ -каналы

وصف الملف: application/pdf

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المؤلفون: A. V. Mukhomedzyanov, M. A. Sirotina, S. V. Logvinov, N. V. Naryzhnaya, А. В. Мухомедзянов, М. А. Сиротина, С. В. Логвинов, Н. В. Нарыжная

المساهمون: The work was funded by the Russian Science Foundation (grant No. 22-25-20001) and the Tomsk Region Administration. The authors thank Dr. med. Sciences, Professor L.N. Maslov for advisory assistance in compiling the review., Работа выполнена при поддержке Российского Научного Фонда (грант № 22-25-20001) и средств Администрации Томской области. Авторы выражают признательность д-ру мед. наук, профессору Л.Н. Маслову за консультативную помощь при составлении обзора.

المصدر: The Siberian Journal of Clinical and Experimental Medicine; Том 38, № 1 (2023); 37-45 ; Сибирский журнал клинической и экспериментальной медицины; Том 38, № 1 (2023); 37-45 ; 2713-265X ; 2713-2927

مصطلحات موضوعية: метаболический синдром, ischemia, reperfusion, remote postconditioning, metabolic syndrome, ишемия, реперфузия, дистантное посткондиционирование

وصف الملف: application/pdf

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الإتاحة: https://doi.org/10.29001/2073-8552-2023-38-1-37-45Test
https://doi.org/10.1056/NEJMoa1208200Test
https://doi.org/10.1007/s00392-016-1017-6Test
https://doi.org/10.2459/JCM.0b013e32835cecc6Test
https://doi.org/10.1007/s00395-005-0539-2Test
https://doi.org/10.1080/14017430600925292Test
https://doi.org/10.1136/hrt.2006.114504Test
https://doi.org/10.1152/ajpheart.00094.2018Test
https://doi.org/10.1080/14017430902866681Test
https://doi.org/10.1161/CIRCRESAHA.110.236190Test

المؤلفون: S. V. Logvinov, L. R. Mustafina, B. K. Kurbatov, M. A. Sirotina, A. S. Gorbunov, N. V. Naryzhnaya, С. В. Логвинов, Л. Р. Мустафина, Б. К. Курбатов, М. A. Сиротина, А. С. Горбунов, Н. В. Нарыжная

المساهمون: The study of myocardial changes in young rats with induced metabolic syndrome was supported by the Russian Science Foundation Grant https://rscf.ru/projectTest /22-25-20001/ and funds from the Administration of the Tomsk Region. Studies of myocardial changes in old rats with induced metabolic syndrome were carried out within the framework of the state task 122020300042-4. The work was performed using the Center for Collective Use “Medical Genomics”., Исследование изменений миокарда у молодых крыс при индуцированном метаболическом синдроме проводилось при поддержке Российского научного фонда Грант https://rscf.ru/projectTest /22-25-20001/ и средств Администрации Томской области. Исследование изменений миокарда у старых крыс при индуцированном метаболическом синдроме осуществлялось в рамках государственного задания 122020300042-4. Работа выполнена с использованием Центра коллективного пользования «Медицинская геномика».

المصدر: The Siberian Journal of Clinical and Experimental Medicine; Том 38, № 1 (2023); 90-98 ; Сибирский журнал клинической и экспериментальной медицины; Том 38, № 1 (2023); 90-98 ; 2713-265X ; 2713-2927

مصطلحات موضوعية: фактор роста соединительной ткани, high-carbohydrate high-fat diet, contracture changes in myocardial cells, fibronectin, TGF-beta 1, CTGF, высокоуглеводная высокожировая диета, контрактурные изменения кардиомиоцитов, фибронектин, трансформирующий фактор роста бета-1

وصف الملف: application/pdf

العلاقة: https://www.sibjcem.ru/jour/article/view/1716/790Test; Sun M., Tan Y., Rexiati M., Dong M., Guo W. Obesity is a common soil for premature cardiac aging and heart diseases – Role of autophagy. Biochim. Biophys. Acta-Mol. Basis Dis. 2019;1865(7):1898–1904. DOI:10.1016/j.bbadis.2018.09.004.; De Castro U.G.M., dos Santos R.A.S.A.S., Silva M.E., de Lima W.G., Campagnole-Santos M.J., Alzamora A.C. Age-dependent effect of high-fructose and high-fat diets on lipid metabolism and lipid accumulation in liver and kidney of rats. Lipids Health Dis. 2013;(12–136). DOI:10.1186/1476-511X-12-136.; Martinelli I., Tomassoni D., Moruzzi M., Roy P., Cifani C., Amenta F. et al. Cardiovascular Changes Related to Metabolic Syndrome: Evidence in Obese Zucker Rats. Int. J. Mol. Sci. 2020;21(6):2035. DOI:10.3390/ijms21062035.; Boyle A.J., Shih H., Hwang J., Ye J., Lee B., Zhang Y. et al. Cardiomyopathy of aging in the mammalian heart is characterized by myocardial hypertrophy, fibrosis and a predisposition towards cardiomyocyte apoptosis and autophagy. Exp. Gerontol. 2011;46(7):549–559. DOI:10.1016/j.exger.2011.02.010.; Piek A., de Boer R.A., Silljé H.H.W. The fibrosis-cell death axis in heart failure. Heart Fail. Rev. 2016;21(2):199-211. DOI:10.1007/s10741-016-9536-9.; Klausner S.C., Schwartz A.B. The aging heart. Clin. Geriatr. Med. 1985;1(1):119-141. URL: https://pubmed.ncbi.nlm.nih.gov/3913496Test/; Tracy E., Rowe G., LeBlanc A.J. Cardiac tissue remodeling in healthy aging: the road to pathology. Am. J. Physiol. Cell Physiol. 2020;319(1):C166–C182. DOI:10.1152/ajpcell.00021.2020.; Nakou E.S., Parthenakis F.I., Kallergis E.M., Marketou M.E., Nakos K.S., Vardas P.E. Healthy aging and myocardium: A complicated process with various effects in cardiac structure and physiology. Int. J. Cardiol. 2016;209:167–175. DOI:10.1016/j.ijcard.2016.02.039.; Logvinov S.V., Naryzhnaya N.V., Kurbatov B.K., Gorbunov A.S., Birulina Y.G., Maslov L.L. et al. High carbohydrate high fat diet causes arterial hypertension and histological changes in the aortic wall in aged rats: The involvement of connective tissue growth factors and fibronectin. Exp. Gerontol. 2021;154:111543. DOI:10.1016/j.exger.2021.111543.; Непомнящих Л.М., Лушникова Е.Л., Семенов Д.Е. Регенераторно-1пластическая недостаточность сердца: Морфологические основы и молекулярные механизмы. М.: Изд-во РАМН; 2003:255.; Kurbatov B.K., Prokudina E.S., Maslov L.N., Naryzhnaya N.V., Logvinov S.V., Gorbunov A.S. et al. The role of adrenergic and muscarinic receptors in stress-induced cardiac injury. Pflugers Arch. 2021; 473(10):1641–1655. DOI:10.1007/s00424-021-02602-6.; Sahraoui A., Dewachter C., de Medina G., Naeije R., Bouguerra S.A., Dewachter L. Myocardial Structural and Biological Anomalies Induced by High Fat Diet in Psammomys obesus Gerbils. PLoS One. 2016;11(2):e0148117. DOI:10.1371/journal.pone.0148117.; Poudyal H., Panchal S.K., Ward L.C., Waanders J., Brown L. Chronic high-carbohydrate, high-fat feeding in rats induces reversible metabolic, cardiovascular, and liver changes. Am. J. Physiol. Endocrinol. Metab. 2012;302(12): E1472–1482. DOI:10.1152/ajpendo.00102.2012.; Bhandarkar N.S., Brown L., Panchal S.K. Chlorogenic acid attenuates high-carbohydrate, high-fat diet-induced cardiovascular, liver, and metabolic changes in rats. Nutr. Res. 2019;62:78–88. DOI:10.1016/j.nutres.2018.11.002.; Elrashidy R. Dysregulation of nuclear factor erythroid 2-related factor 2 signaling and activation of fibrogenic pathways in hearts of high fat diet-fed rats. Mol. Biol. Rep. 2020;47(4):2821–2834. DOI:10.1007/s11033-020-05360-3.; Comunoglu C., Comunoglu N., Eren B., Tanrlöver O., Türkmen N., Gündogmuş U.N. et al. Age-related histopathological changes in the cardiac conducting system in the Turkish population: an evaluation of 202 autopsy cases. Folia Morphol. 2012;71(3):178–182. URL: https://journals.viamedica.pl/folia_morphologica/article/view/18756Test.; Pudil R. Age-related myocardial remodeling: myth or reality? Vnitr. Lek. 2020;66(8):507–511. URL: https://pubmed.ncbi.nlm.nih.gov/33740851Test/; https://www.sibjcem.ru/jour/article/view/1716Test

الإتاحة: https://doi.org/10.29001/2073-8552-2023-38-1-90-98Test
https://doi.org/10.1016/j.bbadis.2018.09.004Test
https://doi.org/10.1186/1476-511X-12-136Test
https://doi.org/10.3390/ijms21062035Test
https://doi.org/10.1016/j.exger.2011.02.010Test
https://doi.org/10.1007/s10741-016-9536-9Test
https://doi.org/10.1152/ajpcell.00021.2020Test
https://doi.org/10.1016/j.ijcard.2016.02.039Test
https://doi.org/10.1016/j.exger.2021.111543Test
https://doi.org/10.1007/s00424-021-02602-6Test

المؤلفون: N. V. Naryzhnaya, A. V. Mukhomedzyanov, B. K. Kurbatov, M. A. Sirotina, M. Kilin, V. N. Azev, L. N. Maslov, Н. В. Нарыжная, А. В. Мухомедзянов, В. К. Курбатов, М. А. Сиротина, М. Килин, В. Н. Азев, Л. Н. Маслов

المساهمون: Работа выполнена при поддержке Российского научного фонда (грант № 22-15-00048). Исследование влияния возраста на инфаркт-лимитирующий эффект дельторфина-II проводили в рамках Гос. задания 122020300042-4. В работе было использовано оборудование Центра коллективного пользования «Медицинская геномика» Томского НИМЦ.

المصدر: Acta Biomedica Scientifica; Том 7, № 6 (2022); 281-289 ; 2587-9596 ; 2541-9420

مصطلحات موضوعية: опиоидные рецепторы, reperfusion, metabolic syndrome, age, opioid receptors, реперфузия, метаболический синдром, возраст

وصف الملف: application/pdf

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الإتاحة: https://doi.org/10.29413/ABS.2022-7.6.29Test
https://doi.org/10.1016/j.carrev.2020.09.032Test
https://doi.org/10.1007/s10517-017-3601-9Test
https://doi.org/10.1016/j.pop.2017.10.003Test
https://doi.org/10.1016/j.jacc.2015.06.1328Test
https://doi.org/10.1038/s41598-021-82398-8Test
https://doi.org/10.1016/j.ecl.2013.09.009Test
https://doi.org/10.29413/ABS.2021-6.4.16Test
https://doi.org/10.3390/cells10030629Test
https://doi.org/10.1016/0002-9149Test(88)90882-x