المساهمون: McKenna, Robert [Univ. of Florida, Gainesville, FL (United States)]

المصدر: Biochemistry; 54; 43

وصف الملف: Medium: ED; Size: 6631-6638

الوصول الحر: http://www.osti.gov/scitech/servlets/purl/1287017Test

المؤلفون: Linda J. Urbanski, Daniela Vullo, Seppo Parkkila, Claudiu T. Supuran

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1088-1092 (2021)

مصطلحات موضوعية: β-carbonic anhydrase, staphylococcus aureus, kinetics, inhibition, anions, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1475-6366Test; https://doaj.org/toc/1475-6374Test

الوصول الحر: https://doaj.org/article/ceafe303fdbe45d391a0c41e20680a80Test

المؤلفون: Ashok Aspatwar, Milka Hammaren, Mataleena Parikka, Seppo Parkkila, Fabrizio Carta, Murat Bozdag, Daniela Vullo, Claudiu T. Supuran

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 65-71 (2020)

مصطلحات موضوعية: β-carbonic anhydrase, monothiocarbamates (mtcs), dithiocarbamate (dtcs), in vitro inhibition, zebrafish larvae, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1475-6366Test; https://doaj.org/toc/1475-6374Test

الوصول الحر: https://doaj.org/article/fcacb8f3654e4041b4b76e82ca83d910Test

المؤلفون: Linda J. Urbanski, Silvia Bua, Andrea Angeli, Marianne Kuuslahti, Vesa. P. Hytönen, Claudiu T. Supuran, Seppo Parkkila

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 1834-1839 (2020)

مصطلحات موضوعية: β-carbonic anhydrase, staphylococcus aureus, kinetics, inhibition, sulphonamides, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1475-6366Test; https://doaj.org/toc/1475-6374Test

الوصول الحر: https://doaj.org/article/290ba6c7433f4c6483a56ded8286952cTest

المؤلفون: Andrea Angeli, Marta Ferraroni, Mariana Pinteala, Stelian S. Maier, Bogdan C. Simionescu, Fabrizio Carta, Sonia Del Prete, Clemente Capasso, Claudiu T. Supuran

المصدر: Molecules; Volume 25; Issue 10; Pages: 2269

مصطلحات موضوعية: β-Carbonic Anhydrase, Burkholderia pseudomallei, crystal structure, type II CA

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Bioorganic Chemistry; https://dx.doi.org/10.3390/molecules25102269Test

الإتاحة: https://doi.org/10.3390/molecules25102269Test

المؤلفون: Verônica da Silva Cardoso, Alane Beatriz Vermelho, Eduardo Ricci Junior, Igor Almeida Rodrigues, Ana Maria Mazotto, Claudiu T. Supuran

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 850-857 (2018)

مصطلحات موضوعية: Sulphonamide, Leishmania, nanoemulsions, β-carbonic anhydrase, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1475-6366Test; https://doaj.org/toc/1475-6374Test

الوصول الحر: https://doaj.org/article/d9bdedfe1f904ab0ada663a683d1f95bTest

المؤلفون: Ashok Aspatwar, Milka Hammarén, Sanni Koskinen, Bruno Luukinen, Harlan Barker, Fabrizio Carta, Claudiu T. Supuran, Mataleena Parikka, Seppo Parkkila

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 832-840 (2017)

مصطلحات موضوعية: Dithiocarbamates, Mycobacterium marinum, β-carbonic anhydrase, in vivo inhibition, zebrafish embryos, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1475-6366Test; https://doaj.org/toc/1475-6374Test

الوصول الحر: https://doaj.org/article/3713130df848413ea6187a1befd2b0f7Test

المؤلفون: Hiromi Kato, Makoto Yoshida, Ryuka Iizuka, Takahiro Ogawa, Yasuhiko Matsushita, Yoko Katayama, Yoshihito Masaki, Yuka Kojima

المصدر: Microbes and Environments. 2021, 36(2):20058

المؤلفون: Akdemir, ATİLLA, ANGELI, A, GÖKTAŞ, F, Eraslan, Elma, KARALı, N, SUPURAN, CT

المساهمون: Inhibition of the b-carbonic anhydrase (CA, EC 4.2.1.1) from pathogenic Candida glabrata (CgNce103) by 1H-indole-2,3-dione 3- N-(4-sulfamoylphenyl)thiosemicarbazones 4a–m was investigated. All the compounds were found to be potent inhibitors of CgNce103, with inhibition constants in the range of 6.4- 63.9 nM. The 5,7-dichloro substituted derivative 4l showed the most effective inhibition (KI of 6.4 nM) as well as the highest selectivity for inhibiting CgNce103 over the cytosolic human (h) isoforms hCA I and II. A possible binding interaction of compound 4l within the active site of CgNce103 has been proposed based on docking studies., AKDEMİR, ATİLLA

مصطلحات موضوعية: Akdemir A., ANGELI A., GÖKTAŞ F., Eraslan E., KARALı N., SUPURAN C., Novel 2-indolinones containing a sulfonamide moiety as selective inhibitors of candida β-carbonic anhydrase enzyme.-, Journal of enzyme inhibition and medicinal chemistry, cilt.34, ss.528-531

الوقت: 2019

وصف الملف: application/pdf

العلاقة: https://hdl.handle.net/20.500.12645/3777Test; WOS:000457960800001; 85061106138

الإتاحة: https://doi.org/20.500.12645/3777Test
https://doi.org/10.3233/dma-2011-0800Test
https://doi.org/10.1080/14756366.2018.1564045Test
https://hdl.handle.net/20.500.12645/3777Test

المؤلفون: Claudiu T. Supuran, Mataleena Parikka, Milka Hammaren, Seppo Parkkila, Daniela Vullo, Murat Bozdag, Ashok Aspatwar, Fabrizio Carta

المساهمون: Lääketieteen ja terveysteknologian tiedekunta - Faculty of Medicine and Health Technology, Tampere University

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 65-71 (2020)

مصطلحات موضوعية: in vitro inhibition, Biolääketieteet - Biomedicine, RM1-950, 01 natural sciences, dithiocarbamate (DTCs), Mycobacterium tuberculosis, monothiocarbamates (MTCs), Drug Discovery, Zebrafish larvae, Dithiocarbamate, Zebrafish, Pharmacology, chemistry.chemical_classification, β-carbonic anhydrase, biology, 010405 organic chemistry, Chemistry, Embryo, General Medicine, biology.organism_classification, In vitro, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Biochemistry, Toxicity, zebrafish larvae, Therapeutics. Pharmacology, Carbonic anhydrase 3, Research Paper

وصف الملف: fulltext

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8cd186d0288cd0369a33e73a2d55d01Test
http://europepmc.org/articles/PMC6830242Test