نتائج البحث - "α-secretase"

1

دورية أكاديمية

Therapeutic effects of a novel synthetic α-secretase

المؤلفون: Sung Bin Kim, Bo-Ram Mun, Sung Yoon Kim, Muthukumar Elangovan, Euy Jun Park, Won-Seok Choi, Woo Jin Park

المصدر: Frontiers in Aging Neuroscience, Vol 16 (2024)

مصطلحات موضوعية: Alzheimer’s disease, amyloid-β clearance, amyloid-β degrading enzyme, synthetic α-secretase, nuclear inclusion a, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fnagi.2024.1383905/fullTest; https://doaj.org/toc/1663-4365Test

الوصول الحر: https://doaj.org/article/9ff45f08edbc4c53b6c59c7b2c1e3e29Test

View record in DOAJ

النص الكامل

2

دورية أكاديمية

A Disintegrin And Metalloprotease 10 expression within the murine central nervous system

المؤلفون: Padilla-Ferrer, Aïda, Carrete, Alex, Simon, Anne, Meffre, Delphine, Jafarian-Tehrani, Mehrnaz

المساهمون: Toxicité environnementale, cibles thérapeutiques, signalisation cellulaire (T3S - UMR_S 1124), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), We acknowledge the non-profit organizations “Fondation des Gueules Cassées” (FGC), ARSEP foundation, Université Paris Cité and Inserm (Institut national de la santé et de la recherche médicale) for financially supporting this work. We acknowledge the core facility of BioMedTech Facilities INSERM US36

المصدر: ISSN: 0006-8993.

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/38548249; hal-04595759; https://u-paris.hal.science/hal-04595759Test; https://u-paris.hal.science/hal-04595759/documentTest; https://u-paris.hal.science/hal-04595759/file/1-s2.0-S0006899324001422-main.pdfTest; PUBMED: 38548249

الإتاحة: https://doi.org/10.1016/j.brainres.2024.148888Test
https://u-paris.hal.science/hal-04595759Test
https://u-paris.hal.science/hal-04595759/documentTest
https://u-paris.hal.science/hal-04595759/file/1-s2.0-S0006899324001422-main.pdfTest

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3

دورية أكاديمية

A Metalloproteinase Cocktail from the Venom of Protobothrops flavoviridis Cleaves Amyloid Beta Peptides at the α-Cleavage Site

المؤلفون: Eugene Futai, Hajime Kawasaki, Shinichi Sato, Khadija Daoudi, Masafumi Hidaka, Taisuke Tomita, Tomohisa Ogawa

المصدر: Toxins, Vol 15, Iss 8, p 500 (2023)

مصطلحات موضوعية: α-secretase, a disintegrin and metalloproteinase (ADAM), Alzheimer’s disease, amyloid beta (Aβ), amyloid precursor protein (APP), snake venom metalloproteinase (SVMP), Medicine

وصف الملف: electronic resource

العلاقة: https://www.mdpi.com/2072-6651/15/8/500Test; https://doaj.org/toc/2072-6651Test

الوصول الحر: https://doaj.org/article/3195de29ae8841c4887c17d1aefa0626Test

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النص الكامل

4

دورية أكاديمية

ADAM10 Gene Variants in AD Patients and Their Relationship to CSF Protein Levels

المؤلفون: Pablo Agüero-Rabes, Julián Pérez-Pérez, Lucía Cremades-Jimeno, María-Salud García-Ayllón, Adriana Gea-González, María José Sainz, Ignacio Mahillo-Fernández, Raquel Téllez, Blanca Cárdaba, Javier Sáez-Valero, Estrella Gómez-Tortosa

المصدر: International Journal of Molecular Sciences; Volume 24; Issue 7; Pages: 6113

مصطلحات موضوعية: Alzheimer’s disease, ADAM10, α-secretase, disintegrin metalloproteinase 10 protein, genetics, CSF biomarkers

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Molecular Neurobiology; https://dx.doi.org/10.3390/ijms24076113Test

الإتاحة: https://doi.org/10.3390/ijms24076113Test

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5

دورية أكاديمية

ADAM10 gene variants in AD patients and their relationship to CSF protein levels

المؤلفون: Agüero-Rabes, Pablo, Pérez-Pérez, Julián, Cremades-Jimeno, Lucía, García-Ayllón, María-Salud, Gea-González, Adriana, Sainz, María José, Mahillo-Fernández, Ignacio, Téllez, Raquel, Cárdaba, Blanca, Sáez-Valero, Javier, Gómez-Tortosa, Estrella

المساهمون: Instituto de Salud Carlos III, Fundación Tatiana Pérez de Guzmán el Bueno, Generalitat Valenciana, European Commission

مصطلحات موضوعية: Alzheimer’s disease, ADAM10, α-secretase, CSF biomarkers, Disintegrin metalloproteinase 10 protein, Genetics

وصف الملف: application/pdf

العلاقة: Publisher's version; The underlying dataset has been published as supplementary material of the article in the publisher platform at DOI 10.3390/ijms24076113; https://doi.org/10.3390/ijms24076113Test; Sí; International Journal of Molecular Sciences 24(7): 6113 (2023); http://hdl.handle.net/10261/335103Test

الإتاحة: https://doi.org/10.3390/ijms24076113Test
http://hdl.handle.net/10261/335103Test

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النص الكامل

6

Phosphorylation of the amyloid precursor protein (APP) at Ser-675 promotes APP processing involving meprin β

المؤلفون: Menon, Preeti Kumaran, Koistinen, Niina Anneli, Iverfeldt, Kerstin, Ström, Anna-Lena

المصدر: Journal of Biological Chemistry. 294(47):17768-17776

مصطلحات موضوعية: amyloid precursor protein (APP), amyloid-beta (Aβ), ADAM, Alzheimer's disease, neurodegeneration, α-secretase 1 (BACE1), APP-CTF, meprin Β, proteolytic processing, neurokemi med molekylär neurobiologi, Neurochemistry with Molecular Neurobiology

وصف الملف: print

الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-178571Test
https://doi.org/10.1074/jbc.RA119.008310Test

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7

تقرير

ADAM10 pharmacological inhibition modifies the expression of components of the dopaminergic system

المؤلفون: Maitra, Subhamita, Vincent, Bruno

المساهمون: Mahidol University Bangkok, Institut de pharmacologie moléculaire et cellulaire (IPMC), Université Nice Sophia Antipolis (1965 - 2019) (UNS)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UniCA)

المصدر: https://hal.science/hal-04234605Test ; 2023.

مصطلحات موضوعية: Alzheimer's disease, neurodegeneration, cognitive deficits, sAPPα, α-secretase, dopaminergic transmission, [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology