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1دورية أكاديميةDiscovery of an In Vivo Chemical Probe for BCL6 Inhibition by Optimization of Tricyclic Quinolinones
المؤلفون: Harnden, Alice C., Davis, Owen A., Box, Gary M., Hayes, Angela, Johnson, Louise D., Henley, Alan T., de Haven Brandon, Alexis K., Valenti, Melanie, Cheung, Kwai-Ming J., Brennan, Alfie, Huckvale, Rosemary, Pierrat, Olivier A., Talbot, Rachel, Bright, Michael D., Akpinar, Hafize Aysin, Miller, Daniel S. J., Tarantino, Dalia, Gowan, Sharon, de Klerk, Selby, McAndrew, Peter Craig, Le Bihan, Yann-Vaï, Meniconi, Mirco, Burke, Rosemary, Kirkin, Vladimir, van Montfort, Rob L. M., Raynaud, Florence I., Rossanese, Olivia W., Bellenie, Benjamin R., Hoelder, Swen
المساهمون: NIHR Biomedical Research Centre, Royal Marsden NHS Foundation Trust/Institute of Cancer Research, Cancer Research UK, CRT Pioneer Fund, Sixth Element Capital
المصدر: Journal of Medicinal Chemistry ; volume 66, issue 8, page 5892-5906 ; ISSN 0022-2623 1520-4804
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2دورية أكاديمية
المؤلفون: Pasqua, A. Elisa, Sharp, Swee Y., Chessum, Nicola E. A., Hayes, Angela, Pellegrino, Loredana, Tucker, Michael J., Miah, Asadh, Wilding, Birgit, Evans, Lindsay E., Rye, Carl S., Mok, N. Yi, Liu, Manjuan, Henley, Alan T., Gowan, Sharon, De Billy, Emmanuel, te Poele, Robert, Powers, Marissa, Eccles, Suzanne A., Clarke, Paul A., Raynaud, Florence I., Workman, Paul, Jones, Keith, Cheeseman, Matthew D.
المساهمون: Cancer Research UK, Battle Against Cancer Investment Trust, Cancer Research Technology Pioneer Fund
المصدر: Journal of Medicinal Chemistry ; volume 66, issue 8, page 5907-5936 ; ISSN 0022-2623 1520-4804
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3دورية أكاديمية
المؤلفون: Huckvale, Rosemary, Harnden, Alice C., Cheung, Kwai-Ming J., Pierrat, Olivier A., Talbot, Rachel, Box, Gary M., Henley, Alan T., de Haven Brandon, Alexis K., Hallsworth, Albert E., Bright, Michael D., Akpinar, Hafize Aysin, Miller, Daniel S. J., Tarantino, Dalia, Gowan, Sharon, Hayes, Angela, Gunnell, Emma A., Brennan, Alfie, Davis, Owen A., Johnson, Louise D., de Klerk, Selby, McAndrew, Craig, Le Bihan, Yann-Vaï, Meniconi, Mirco, Burke, Rosemary, Kirkin, Vladimir, van Montfort, Rob L. M., Raynaud, Florence I., Rossanese, Olivia W., Bellenie, Benjamin R., Hoelder, Swen
المساهمون: Cancer Research UK, Sixth Element Capital
المصدر: Journal of Medicinal Chemistry ; volume 65, issue 12, page 8191-8207 ; ISSN 0022-2623 1520-4804
مصطلحات موضوعية: Drug Discovery, Molecular Medicine
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4دورية أكاديمية
المؤلفون: Bellenie, Benjamin R., Cheung, Kwai-Ming J., Varela, Ana, Pierrat, Olivier A., Collie, Gavin W., Box, Gary M., Bright, Michael D., Gowan, Sharon, Hayes, Angela, Rodrigues, Matthew J., Shetty, Kartika N., Carter, Michael, Davis, Owen A., Henley, Alan T., Innocenti, Paolo, Johnson, Louise D., Liu, Manjuan, de Klerk, Selby, Le Bihan, Yann-Vaï, Lloyd, Matthew G., McAndrew, P. Craig, Shehu, Erald, Talbot, Rachel, Woodward, Hannah L., Burke, Rosemary, Kirkin, Vladimir, van Montfort, Rob L. M., Raynaud, Florence I., Rossanese, Olivia W., Hoelder, Swen
المساهمون: Cancer Research UK, European investment fund, Cancer Research Technology
المصدر: Journal of Medicinal Chemistry ; volume 63, issue 8, page 4047-4068 ; ISSN 0022-2623 1520-4804
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5دورية أكاديمية
المؤلفون: Read, Martin, Harrison, R. John, Romagnoli, Barbara, Tanious, Farial A., Gowan, Sharon H., Reszka, Anthony P., Wilson, W. David, Kelland, Lloyd R., Neidle, Stephen
المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2001 Apr . 98(9), 4844-4849.
الوصول الحر: https://www.jstor.org/stable/3055526Test
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6دورية أكاديمية
المؤلفون: Andrejeva, Gabriela, Gowan, Sharon, Lin, Gigin, Wong Te Fong, Anne Christine LF, Shamsaei, Elham, Parkes, Harry G., Mui, James, Raynaud, Florence I., Asad, Yasmin, Vizcay-Barrena, Gema, Nikitorowicz-Buniak, Joanna, Valenti, Melanie, Howell, Louise, Fleck, Roland A., Martin, Lesley Ann, Kirkin, Vladimir, Leach, Martin O., Chung, Yuen Li
المصدر: Andrejeva , G , Gowan , S , Lin , G , Wong Te Fong , A C LF , Shamsaei , E , Parkes , H G , Mui , J , Raynaud , F I , Asad , Y , Vizcay-Barrena , G , Nikitorowicz-Buniak , J , Valenti , M , Howell , L , Fleck , R A , Martin , L A , Kirkin , V , Leach , M O & Chung , Y L 2019 , ' De novo phosphatidylcholine synthesis is required for autophagosome membrane formation and maintenance during autophagy ' ....
مصطلحات موضوعية: Autophagosome, autophagy, choline phospholipids, CTP:phosphocholine cytidylyltransferase, phosphatidylcholine, propargylcholine
الإتاحة: https://doi.org/10.1080/15548627.2019.1659608Test
https://kclpure.kcl.ac.uk/portal/en/publications/ef637dcb-362c-4fd8-9f92-f838ce4f1d45Test
http://www.scopus.com/inward/record.url?scp=85073817643&partnerID=8YFLogxKTest -
7دورية أكاديمية
المؤلفون: Al-Saffar, Nada M. S., Troy, Helen, Wong Te Fong, Anne-Christine, Paravati, Roberta, Jackson, L. Elizabeth, Gowan, Sharon, Boult, Jessica K. R., Robinson, Simon P., Eccles, Suzanne A., Yap, Timothy A., Leach, Martin O., Chung, Yuen-Li
المصدر: British Journal of Cancer ; volume 119, issue 9, page 1118-1128 ; ISSN 0007-0920 1532-1827
مصطلحات موضوعية: Cancer Research, Oncology
الإتاحة: https://doi.org/10.1038/s41416-018-0242-3Test
http://www.nature.com/articles/s41416-018-0242-3Test
http://www.nature.com/articles/s41416-018-0242-3.pdfTest -
8دورية أكاديمية
المؤلفون: Tucker, Elizabeth R., Tall, Jennifer R., Danielson, Laura S., Gowan, Sharon, Jamin, Yann, Robinson, Simon P., Banerji, Udai, Chesler, Louis
المساهمون: Medical Research Council and SPARKS Clinical Research Training Fellowship, Abbie's Fund, Cancer Research UK Project
المصدر: Molecular Oncology ; volume 11, issue 8, page 996-1006 ; ISSN 1574-7891 1878-0261
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9دورية أكاديمية
المؤلفون: Clarke, Paul A., Ortiz-Ruiz, Maria-Jesus, TePoele, Robert, Adeniji-Popoola, Olajumoke, Box, Gary, Court, Will, Czasch, Stefanie, El Bawab, Samer, Esdar, Christina, Ewan, Ken, Gowan, Sharon, De Haven Brandon, Alexis, Hewitt, Phllip, Hobbs, Stephen M., Kaufmann, Wolfgang, Mallinger, Aurélie, Raynaud, Florence, Roe, Toby, Rohdich, Felix, Schiemann, Kai, Simon, Stephanie, Schneider, Richard, Valenti, Melanie, Weigt, Stefan, Blagg, Julian, Blaukat, Andree, Dale, Trevor C., Eccles, Suzanne A., Hecht, Stefan, Urbahns, Klaus, Workman, Paul, Wienke, Dirk
وصف الملف: application/pdf
العلاقة: https://orca.cardiff.ac.uk/id/eprint/96966/1/elife-20722-v3.pdfTest; Clarke, Paul A., Ortiz-Ruiz, Maria-Jesus, TePoele, Robert, Adeniji-Popoola, Olajumoke, Box, Gary, Court, Will, Czasch, Stefanie, El Bawab, Samer, Esdar, Christina, Ewan, Ken orcid:0000-0001-6622-9009 orcid:0000-0001-6622-9009, Gowan, Sharon, De Haven Brandon, Alexis, Hewitt, Phllip, Hobbs, Stephen M., Kaufmann, Wolfgang, Mallinger, Aurélie, Raynaud, Florence, Roe, Toby, Rohdich, Felix, Schiemann, Kai, Simon, Stephanie, Schneider, Richard, Valenti, Melanie, Weigt, Stefan, Blagg, Julian, Blaukat, Andree, Dale, Trevor C. https://orca.cardiff.ac.uk/view/cardiffauthors/A050728Q.htmlTest orcid:0000-0002-4880-9963 orcid:0000-0002-4880-9963, Eccles, Suzanne A., Hecht, Stefan, Urbahns, Klaus, Workman, Paul and Wienke, Dirk 2016. Assessing the mechanism and therapeutic potential of modulators of the human Mediator complex-associated protein kinases. eLife 5 , e20722. 10.7554/eLife.20722 https://doi.org/10.7554/eLife.20722Test file https://orca.cardiff.ac.uk/id/eprint/96966/1/elife-20722-v3.pdfTest
الإتاحة: https://doi.org/10.7554/eLife.20722Test
https://orca.cardiff.ac.uk/id/eprint/96966Test/
https://orca.cardiff.ac.uk/id/eprint/96966/1/elife-20722-v3.pdfTest -
10دورية أكاديمية
المؤلفون: Naseem, Afia, Pal, Akos, Gowan, Sharon, Asad, Yasmin, Donovan, Adam, Temesszentandrási-Ambrus, Csilla, Kis, Emese, Gaborik, Zsuzsanna, Bhalay, Gurdip, Raynaud, Florence
المصدر: Cells (2073-4409); Oct2022, Vol. 11 Issue 20, p3286-N.PAG, 20p
مصطلحات موضوعية: LIQUID chromatography-mass spectrometry, METABOLOMICS, CELL permeability, THYMIDYLATE synthase, METHYLENETETRAHYDROFOLATE reductase