دورية أكاديمية

Diagnosing breast cancer: an opportunity for innovative engineering

التفاصيل البيبلوغرافية
العنوان: Diagnosing breast cancer: an opportunity for innovative engineering
المؤلفون: Vaughan, Christopher L, Evans, Michael D
المساهمون: Innovation Fund, National Institutes of Health, Industrial Development Corporation
المصدر: South African Medical Journal; Vol 102, No 6 (2012); 562-564 ; 2078-5135 ; 0256-9574
بيانات النشر: South African Medical Association
سنة النشر: 2012
المجموعة: South African Medical Journal (SAMJ)
مصطلحات موضوعية: Radiology, Biomedical Engineering, Breast Cancer, Diagnosis, X-rays, Ultrasound, Tomosynthesis, Medical Imaging
جغرافية الموضوع: World, South Africa, From 2, Not applicable
الوقت: From 2,500 BC to present time
الوصف: Background. In an ancient papyrus, dating back to 2500 BC, an Egyptian named Imhotep, thought to be the first physician and engineer in history, offers a glimpse into the earliest recorded case of breast cancer. Treatment has evolved over the years, from radical mastectomy to radiation by X-rays, and from adjuvant chemotherapy to hormonal therapy. A key challenge in fighting the ‘war’ on breast cancer is early diagnosis and here innovative engineers play a vital role. Aims. While full-field digital mammography has emerged in the past decade, this technique suffers from relatively high dose levels and poor sensitivity when the breasts are dense. We aimed to develop a diagnostic imaging system that exposes the patient to lower ionising radiation and improves the sensitivity and specificity for women with dense breasts. Results. Our PantoScanner platform has been designed to implement slot scanning digital X-rays, thereby lowering the dose and increasing signal-to-noise ratio, while also accommodating automated ultrasound and digital tomosynthesis. Early results based on mammographic phantoms are encouraging while the PantoScanner is undergoing clinical testing prior to commercial release. Conclusion. Since breast cancer kills 500 000 people globally every year, early diagnosis by breast screening could save the lives of many women. Our fervent hope is that the PantoScanner system will significantly contribute to this effort in South Africa and around the world.
نوع الوثيقة: article in journal/newspaper
وصف الملف: application/pdf; text/html
اللغة: English
العلاقة: http://samj.org.za/index.php/samj/article/view/5607/4192Test; http://samj.org.za/index.php/samj/article/view/5607/4250Test; http://samj.org.za/index.php/samj/article/downloadSuppFile/5607/2554Test; http://samj.org.za/index.php/samj/article/downloadSuppFile/5607/2555Test; http://samj.org.za/index.php/samj/article/downloadSuppFile/5607/2556Test; http://samj.org.za/index.php/samj/article/downloadSuppFile/5607/2557Test; http://samj.org.za/index.php/samj/article/downloadSuppFile/5607/2558Test; http://samj.org.za/index.php/samj/article/downloadSuppFile/5607/2559Test; http://samj.org.za/index.php/samj/article/downloadSuppFile/5607/2560Test; http://samj.org.za/index.php/samj/article/downloadSuppFile/5607/2561Test; http://samj.org.za/index.php/samj/article/downloadSuppFile/5607/2562Test; http://samj.org.za/index.php/samj/article/view/5607Test
DOI: 10.7196/SAMJ.5607
الإتاحة: https://doi.org/10.7196/SAMJ.5607Test
http://samj.org.za/index.php/samj/article/view/5607Test
حقوق: Copyright of published material remains in the Authors’ name. This allows authors to use their work for their own non-commercial purposes without seeking permission from the Publisher, subject to properly acknowledging the Journal as the original place of publication. Authors are free to copy, print and distribute their articles, in full or in part, for teaching activities, and to deposit or include their work in their own personal or institutional database or on-line website. Authors are requested to inform the Journal/Publishers of their desire/intention to include their work in a thesis or dissertation or to republish their work in any derivative form (but not for commercial use). Material submitted for publication in the SAMJ is accepted provided it has not been published or submitted for publication elsewhere. Please inform the editorial team if the main findings of your paper have been presented at a conference and published in abstract form, to avoid copyright infringement.
رقم الانضمام: edsbas.5F86394B
قاعدة البيانات: BASE