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المؤلفون: Julia Bier, Joanne Smart, Melanie Wong, Gulbu Uzel, Henry Brigden, Isabelle Meyts, Luigi D. Notarangelo, Amanda J. Russell, Lucinda J. Berglund, Katherine J. L. Jackson, Stuart G. Tangye, Joanne H. Reed, Sharon Choo, Paul Gray, Kaan Boztug, Danielle T. Avery, Stefano Volpi, Christopher C. Goodnow, Robert Brink, Helen Lenthall, Michael O'Sullivan, Theresa Cole, Anthony Lau, Peter Hsu, Elissa K. Deenick
المصدر: The Journal of Experimental Medicine
مصطلحات موضوعية: Male, Class I Phosphatidylinositol 3-Kinases, Plasma Cells, Immunology, Autoimmunity, Mice, Transgenic, Biology, medicine.disease_cause, Autoantigens, Article, Mice, Immune Tolerance, medicine, Animals, Humans, Immunology and Allergy, Research Articles, B cell, Autoantibodies, Autoantibody, Germinal center, Peripheral tolerance, Germinal Center, Mice, Inbred C57BL, medicine.anatomical_structure, Immunoglobulin M, P110δ, Gain of Function Mutation, Antibody Formation, biology.protein, Female, Antibody, Signal Transduction
وصف الملف: Print
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06a467e437cb439bb2cab65f6c5b4da8Test
http://hdl.handle.net/11567/1024151Test -
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المؤلفون: Marco Ritelli, Harry C. Dietz, Danielle T. Avery, Bertrand Boisson, Soraya Boucherit, Lucie Grodecká, Stuart G. Tangye, Romain Lévy, Kathryn Payne, Tomáš Freiberger, Sophie Cypowyj, Juan Li, Valérie Cormier-Daire, Nicoletta Zoppi, Laurent Abel, Geetha Rao, Vivien Béziat, Andrea Guennoun, Benedetta Bigio, Maya Chrabieh, Salim Bougarn, Marina Colombi, Lei Shang, Emilie Corvilain, Yuval Itan, Anne Puel, Franck Rapaport, Nico Marr, Fransiska Malfait, Delfien Syx, Mélanie Migaud, Tanwir Habib, Sabri Boughorbel, Jean-Laurent Casanova, Cindy S. Ma
المصدر: Science Immunology. 4
مصطلحات موضوعية: Male, 0301 basic medicine, Connective Tissue Disorder, MAPK8, Immunology, Mucocutaneous zone, Connective tissue, Extracellular matrix, 03 medical and health sciences, 0302 clinical medicine, Transforming Growth Factor beta, medicine, Humans, Mitogen-Activated Protein Kinase 8, Chronic mucocutaneous candidiasis, Connective Tissue Diseases, Alleles, Cells, Cultured, business.industry, Candidiasis, Chronic Mucocutaneous, Interleukin-17, General Medicine, medicine.disease, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Mutation, Cancer research, Female, Signal transduction, Haploinsufficiency, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d854a53b130f2af964f8eaeac6b479eTest
https://doi.org/10.1126/sciimmunol.aax7965Test -
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المؤلفون: Helen Lenthall, Isabelle Meyts, Robert Brink, Kathryn Payne, Christoph Burkhart, Kaan Boztug, Wei Shi, Elise French, Melanie Wong, Lynn M. Corcoran, Gulbu Uzel, William A. Sewell, Michael O'Sullivan, Lucinda J. Berglund, Danielle T. Avery, Alisa Kane, David Zahra, Paul Gray, Danyal Butt, Tri Giang Phan, Anthony Lau, Sharon Choo, Stuart G. Tangye, Henry Brigden, Peter Hsu, Elissa K. Deenick, Jana R. Hermes, Theresa Cole, Tina Nguyen, Michael Elliott, Cindy S. Ma, Julia Bier, Steven M. Holland, Akira Nguyen
المصدر: The Journal of Experimental Medicine
مصطلحات موضوعية: 0301 basic medicine, Cellular differentiation, Antibody Affinity, PI3 KINASE, Research & Experimental Medicine, PHOSPHOINOSITIDE 3-KINASE, medicine.disease_cause, CLASS-SWITCH RECOMBINATION, Mice, Phosphatidylinositol 3-Kinases, HUMAN IMMUNODEFICIENCY, SECRETING CELLS, Immunology and Allergy, Child, Research Articles, B-Lymphocytes, Mutation, biology, Cell Differentiation, Cytidine deaminase, ANTIBODY-PRODUCTION, 3. Good health, Cell biology, Phenotype, medicine.anatomical_structure, ANTIGEN AFFINITY, Medicine, Research & Experimental, Gain of Function Mutation, Models, Animal, PHOSPHATIDYLINOSITOL 3-KINASE, Antibody, Life Sciences & Biomedicine, Signal Transduction, Class I Phosphatidylinositol 3-Kinases, Plasma Cells, Immunology, Immunoglobulins, Bone Marrow Cells, Article, 03 medical and health sciences, Germline mutation, Immune system, medicine, 3-KINASE DELTA SYNDROME, Animals, Humans, Germ-Line Mutation, B cell, Cell Proliferation, P85-ALPHA SUBUNIT, Science & Technology, Interleukins, biochemical phenomena, metabolism, and nutrition, Immunoglobulin Class Switching, 030104 developmental biology, Immunoglobulin class switching, biology.protein
وصف الملف: Print-Electronic
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb0e6265bfc33cb2d8fc21980955e4a9Test
https://doi.org/10.1084/jem.20180010Test -
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المؤلفون: Danielle T. Avery, Rita Beier, Annaliesse Blincoe, Rubén Martínez-Barricarte, David A. Fulcher, Jamila El Baghdadi, Aydan Ikinciogullari, Sara Sebnem Kilic, Yoshiyuki Minegishi, Geetha Rao, Capucine Picard, Melanie Wong, Kathryn Payne, Michael Stormon, Polina Stepensky, Gulbu Uzel, Paul Gray, Stephen Adelstein, Martyn A. French, Masao Kobayashi, Matthew C. Cook, Jean-Laurent Casanova, Klaus Warnatz, Stuart G. Tangye, Bodo Grimbacher, Aziz Bousfiha, Stéphanie Boisson-Dupuis, Natalie Wong, Patrick O’Young, Tri Giang Phan, Akira Nguyen, James Torpy, Michael Elliott, Cindy S. Ma, John B. Ziegler, Steven M. Holland, Peter Hsu, Elissa K. Deenick, Satoshi Okada, Jacinta Bustamante, Sophie Hambleton, Dianne E. Campbell, Anne Puel, Peter D. Arkwright, Kaan Boztug, Nic Robertson
المساهمون: Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Anabilim Dalı., Kılıç, Sara Şebnem, AAH-1658-2021
المصدر: The Journal of Experimental Medicine
Ma, C S, Wong, N, Rao, G, Nguyen, A, Avery, D T, Payne, K, Torpy, J, O'Young, P, Deenick, E, Bustamante, J, Puel, A, Okada, S, Kobayashi, M, Martinez-Barricarte, R, Elliott, M, Kilic, S S, Baghdadi, J E, Minegishi, Y, Bousfiha, A, Robertson, N, Hambleton, S, Arkwright, P, French, M, Blincoe, A K, Hsu, P, Campbell, D E, Stormon, M O, Wong, M, Adelstein, S, Fulcher, D A, Cook, M C, Stepensky, P, Boztug, K, Beier, R, Ikincioğullari, A, Ziegler, J B, Gray, P, Picard, C, Boisson-Dupuis, S, Phan, T G, Grimbacher, B, Warnatz, K, Holland, S M, Uzel, G, Casanova, J L & Tangye, S G 2016, ' Unique and shared signaling pathways cooperate to regulate the differentiation of human CD4 + T cells into distinct effector subsets ', Journal of Experimental Medicine, vol. 213, no. 8, pp. 1589-1608 . https://doi.org/10.1084/jem.20151467Testمصطلحات موضوعية: Male, 0301 basic medicine, Interleukin 12 receptor beta1, STAT6 protein, Cellular differentiation, Immune deficiency, Medizin, Follicular-helper-cells, STAT1 gene, Ectodermal dysplasia, medicine.disease_cause, STAT1 protein, human, Gene, Essential modulator mutation, Differentiation antigen, Chronic mucocutaneous candidiasis, Interleukin 10, Hyper-ige syndrome, Icos deficiency, STAT4 protein, Gain of function mutation, Immunology and Allergy, Research Articles, Priority journal, Th17 cell, Mutation, Th1 cell, Effector, Cell Differentiation, Interleukin-10, 3. Good health, Cell biology, Lymphocyte differentiation, STAT1 Transcription Factor, medicine.anatomical_structure, Intracellular signaling, Effector cell, Female, BCL6 expression, Signal transduction, CD4 antigen, Protein kinase TYK2, Human, STAT3 Transcription Factor, Cell subpopulation, T cell, IL10 protein, mouse, Immunology, Helper Cell, Germinal Center, Tfh Cell, Biology, Gamma interferon receptor, STAT3 gene, Article, Common variable immunodeficiency, Antibody-responses, Immunomodulation, 03 medical and health sciences, Protein phosphorylation, Th2 Cells, Immune system, STAT3 protein, Antigen, STAT1 protein, Genetics, medicine, Humans, Th0 cell, Medicine, research & experimental, Cytokine release, Gamma interferon, Infection sensitivity, L kappa B kinase gamma, CD4+ T lymphocyte, Immunoregulation, In vitro study, Th1 Cells, Interleukin 21 receptor, Antigens, Differentiation, Humoral immunity, Interleukin 21, Th2 cell, 030104 developmental biology, Human cell, Th17 Cells, Cytology, IL-10 production, Controlled study
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dee2b2bc49c951ae46185f318cb05abbTest
http://repo.lib.tokushima-u.ac.jp/115511Test -
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المؤلفون: Fabienne Mackay, Danielle T. Avery, Kristy O'Donnell, Simona Infantino, Stuart G. Tangye, Vanessa L. Bryant, Gabrielle T. Belz, Michael Elliott, David M. Tarlinton, Amanda Light, Stéphane Richard
المصدر: Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)مصطلحات موضوعية: 0301 basic medicine, Cell signaling, Protein-Arginine N-Methyltransferases, Arginine, Cellular differentiation, Science, B-cell receptor, General Physics and Astronomy, Biology, Lymphocyte Activation, Methylation, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, medicine, Animals, Humans, lcsh:Science, B cell, B-Lymphocytes, Multidisciplinary, Germinal center, Cell Differentiation, General Chemistry, 3. Good health, Cell biology, Immunity, Humoral, Repressor Proteins, 030104 developmental biology, medicine.anatomical_structure, Biochemistry, 030220 oncology & carcinogenesis, lcsh:Q, Signal transduction, Protein Processing, Post-Translational
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea770da252488a40c3e6392d28050717Test
http://europepmc.org/articles/PMC5638811Test -
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المؤلفون: Cindy S. Ma, Christoph Klein, Anna Chan, Stéphanie Boisson-Dupuis, Diana Averbuch, Megan L. Ives, Stephen Adelstein, Jean-Laurent Casanova, David A. Fulcher, Dan Engelhard, Peter D. Arkwright, Anne Durandy, Gulbu Uzel, Jane Peake, Masao Kobayashi, Matthew C. Cook, Sharon Choo, Stuart G. Tangye, Danielle T. Avery, Jennifer Stoddard, Martyn A. French, Steven M. Holland, Lucinda J. Berglund, Elissa K. Deenick, Jacinta Bustamante, Melanie Wong, Miyuki Tsumura, Capucine Picard, Joanne Smart, Joachim Roesler, Leen Moens
المصدر: The Journal of Experimental Medicine
مصطلحات موضوعية: STAT3 Transcription Factor, Cellular differentiation, Immunology, Naive B cell, Plasma Cells, Immunoglobulin G, Atacicept, Article, 03 medical and health sciences, 0302 clinical medicine, Antigen, medicine, STAT5 Transcription Factor, Immunology and Allergy, Humans, Cell Lineage, Memory B cell, 030304 developmental biology, 0303 health sciences, B-Lymphocytes, CD40, biology, Interleukins, Interleukin-21 Receptor alpha Subunit, Cell Differentiation, medicine.disease, 3. Good health, Cell biology, Interleukin-10, Tumor Necrosis Factor Receptor Superfamily, Member 7, B-1 cell, STAT1 Transcription Factor, Mutation, biology.protein, Immunologic Memory, 030215 immunology, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c7412c58cb8ae777d42a735e4972ddTest
http://europepmc.org/articles/PMC3832925Test -
7
المؤلفون: Martyn A. French, Sharon Choo, Jean-Laurent Casanova, Klaus Magdorf, Stéphanie Boisson-Dupuis, Cindy S. Ma, Melanie Wong, Joanne Smart, Dan Engelhard, Alexandra Y. Kreins, Jane Peake, David A. Fulcher, Peter D. Arkwright, Anna Chan, Paul Gray, Sara Sebnem Kilic, Yoshiyuki Minegishi, Diana Averbuch, Elissa K. Deenick, Jacinta Bustamante, Marcel Batten, Matthew C. Cook, Stuart G. Tangye, Danielle T. Avery, Shigeaki Nonoyama
المساهمون: Uludağ Üniversitesi/Tıp Fakültesi/Pediatri Anabilim Dalı., Kılıç, Sara Şebnem, AAH-1658-2021
المصدر: Blood. 119:3997-4008
مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Interleukin 12 receptor beta1, Cellular differentiation, Lymphocyte Activation, Biochemistry, CXCR5, Protein bcl 6, Tyrosine phosphorylation, Interleukin 12, In vivo study, Mice, Interleukin 21, Icos, Cytotoxic T cell, Helper Cell, Germinal Center, Interleukin-21, Cells, Cultured, Priority journal, B-Lymphocytes, Cxc chemokine receptor-5, Chemokine receptor cxcr5, Receptors, Interleukin-12, Cell Differentiation, T-Lymphocytes, Helper-Inducer, Hematology, BCL6, Protein kinase tyk2, Interleukin-12, Lymphocyte differentiation, STAT1 Transcription Factor, Differentiation, Helper cell, Cytokines, Mutations, Human, Signal Transduction, Adult, STAT3 Transcription Factor, Adolescent, Il-21, Bcl6, Immunology, Biology, Stat1 protein, Article, Antibody-responses, Immunocompromised Host, Animals, Humans, Mycobacterial, Th17 cells, Gene mutation, Immunobiology, Cell lineage, TYK2 Kinase, CD4+ T lymphocyte, B lymphocyte, Cell growth, In vitro study, Cell Biology, Human cell, Cell culture, Mutation, Cancer research, Protein expression, Cell maturation, Cell line, Stat3 protein, Controlled study, Transcription Factors
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49d91e41ee7cd7c3df59b9257d69ecadTest
https://doi.org/10.1182/blood-2011-11-392985Test -
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المؤلفون: Jane Peake, Danielle T. Avery, Umamainthan Palendira, Martyn A. French, Robert Brink, Klaus Magdorf, Santi Suryani, Jean-Laurent Casanova, Karl Bleasel, Sami Al-Hajjar, D. Sean Riminton, Joachim Roesler, Gary Y. Chew, Nicholas Simpson, Cecile King, Dan Engelhard, Cindy S. Ma, Matthew C. Cook, Stuart G. Tangye, Tyani D. Chan, Melanie Wong, Stéphanie Boisson-Dupuis, Elissa K. Deenick, Jacinta Bustamante, Peter D. Arkwright, David A. Fulcher, Saleh Al-Muhsen, Sharon Choo, Pravin Hissaria
المساهمون: Faculty of Science and Engineering
المصدر: The Journal of Experimental Medicine
Journal of Experimental Medicine, 207(1), 155-171. ROCKEFELLER UNIV PRESSمصطلحات موضوعية: STAT3 Transcription Factor, Time Factors, Cellular differentiation, Plasma Cells, Immunology, B-cell receptor, Naive B cell, Immunoglobulins, Biology, Immunoglobulin secretion, Article, FOLLICULAR-HELPER-CELLS, HYPERIMMUNOGLOBULIN-E, SECRETING CELLS, COMMON GAMMA-CHAIN, medicine, Humans, Immunology and Allergy, Antigens, Memory B cell, JOBS SYNDROME, B cell, Common gamma chain, STAPHYLOCOCCUS-AUREUS, HYPER-IGE SYNDROME, CUTTING EDGE, PRIMARY IMMUNODEFICIENCY DISEASES, Interleukins, Cell Differentiation, LINKED LYMPHOPROLIFERATIVE DISEASE, Cell biology, B-1 cell, STAT1 Transcription Factor, medicine.anatomical_structure, Antibody Formation, Immunologic Memory, Signal Transduction
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0727e27cbda562a96925f265ca5d114bTest
https://hdl.handle.net/11370/4d7bc2b8-2398-450e-85ae-55b8e29b249bTest -
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المؤلفون: Danielle T. Avery, Danyal Butt, Antony Basten, Aaron L. Statham, Jana R. Hermes, Stuart G. Tangye, Katherine Bourne, Robert Brink, Nike Julia Krautler, Dan Suan, Clara Young, Michael Elliott, Marcel E. Dinger, Jesper L.V. Maag
المصدر: Immunity. 47:1142-1153.e4
مصطلحات موضوعية: Receptors, CCR6, 0301 basic medicine, Receptors, CXCR4, Plasma Cells, Immunology, Mice, Transgenic, C-C chemokine receptor type 6, Biology, Immunophenotyping, Mice, 03 medical and health sciences, Chemokine receptor, Antigen, Gene expression, polycyclic compounds, Animals, Humans, Immunology and Allergy, Cell Lineage, Memory B cell, Gene Expression Profiling, Precursor Cells, B-Lymphoid, Germinal center, Cell Differentiation, Germinal Center, Molecular biology, Phenotype, Immunity, Humoral, Mice, Inbred C57BL, 030104 developmental biology, Infectious Diseases, Gene Expression Regulation, Humoral immunity, bacteria, B7-2 Antigen, Positive Regulatory Domain I-Binding Factor 1, Immunologic Memory, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca8a7f7d202fe106a0cdbd17a90a99eTest
https://doi.org/10.1016/j.immuni.2017.11.022Test -
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المؤلفون: Geetha Rao, Dianne E. Campbell, Anne Puel, Masao Kobayashi, Matthew C. Cook, Sara Sebnem Kilic, Danielle T. Avery, Rita Beier, Polina Stepensky, Stéphanie Boisson-Dupuis, Yoshiyuki Minegishi, Stuart G. Tangye, Davood Mansouri, Michael Stormon, Satoshi Okada, Shigeaki Nonoyama, Thomas Hambridge, Jean-Laurent Casanova, Stephen Adelstein, Joanne Smart, David A. Fulcher, Klaus Warnatz, Kaan Boztug, Kathryn Payne, Tony Roscioli, Annaliesse Blincoe, Steven M. Holland, Aydan Kansu, Gulbu Uzel, Jamila El Baghdadi, Bodo Grimbacher, Aziz Bousfiha, James Torpy, Seyed Alireza Mahdaviani, Capucine Picard, Simon J. Pelham, Aydan Ikinciogullari, Natalie Wong, Paul Gray, Martyn A. French, Tri Giang Phan, Melanie Wong, Cindy S. Ma, Ulrich Baumann, Peter Hsu, Elissa K. Deenick, Jacinta Bustamante, Peter D. Arkwright, John B. Ziegler, Jennifer Stoddard
المصدر: The Journal of allergy and clinical immunology. 136(4)
مصطلحات موضوعية: STAT3 Transcription Factor, Cellular differentiation, Immunology, Cell, CD40 Ligand, Medizin, medicine.disease_cause, Lymphocyte Activation, Article, Autoimmunity, Inducible T-Cell Co-Stimulator Protein, Interferon-gamma, Immune system, T-Lymphocyte Subsets, medicine, Agammaglobulinaemia Tyrosine Kinase, Immunology and Allergy, Bruton's tyrosine kinase, Humans, Receptors, Cytokine, Immunodeficiency, Cells, Cultured, Cell Proliferation, B-Lymphocytes, biology, Immunologic Deficiency Syndromes, Cell Differentiation, T-Lymphocytes, Helper-Inducer, Protein-Tyrosine Kinases, medicine.disease, Phenotype, I-kappa B Kinase, Immunity, Humoral, medicine.anatomical_structure, STAT1 Transcription Factor, Humoral immunity, Mutation, biology.protein, Immunologic Memory, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa0b2dd22d1418555169863e84a7aebcTest
https://pubmed.ncbi.nlm.nih.gov/26162572Test