التفاصيل البيبلوغرافية
العنوان:
Real world safety and efficacy of the Janus Tacrolimus-Eluting stent: long-term clinical outcome and angiographic findings from the Tacrolimus-Eluting STent (TEST) registry
المؤلفون:
Damiana Fiscella , Davide Capodanno , Piera Capranzano , Francesca Mirabella , George Dangas , Rosario Parisi , Francesco Scardaci , Roxana Mehran , Maria Elena Di Salvo , Gianpaolo Ussia , Alfredo R. Galassi , Corrado Tamburino
المساهمون:
Tamburino C., Di Silvo M.E., Capodanno D., Capranzano P., Parisi R., Mirabella F., Scardaci F., Ussia G., Galassi A.R., Fiscella D., Mehran R., Dangas G.
المصدر:
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac AngiographyInterventions . 73(2)
سنة النشر:
2009
مصطلحات موضوعية:
Male , medicine.medical_specialty , Time Factors , medicine.medical_treatment , Population , Myocardial Infarction , Restenosi , Kaplan-Meier Estimate , Coronary Angiography , Prosthesis Design , Risk Assessment , Tacrolimus , Coronary Restenosis , Restenosis , medicine , Humans , Radiology, Nuclear Medicine and imaging , Myocardial infarction , Prospective Studies , Registries , Angioplasty, Balloon, Coronary , education , Aged , education.field_of_study , business.industry , Coronary Stenosis , Stent , Percutaneous coronary intervention , Tacrolimus eluting stent , Cardiovascular Agents , Drug-Eluting Stents , General Medicine , Middle Aged , medicine.disease , Surgery , Treatment Outcome , Antiproliferative Agents , Female , Radiology , Safety , Cardiology and Cardiovascular Medicine , business , Mace
الوصف:
Objectives: We sought to evaluate the safety and performance of the Janus Tacrolimus-Eluting stent (TES) in an unselected population of patients, without application of restrictive clinical or angiographic criteria. Background: Continued attention to the safety, efficacy, and deliverability of first-generation drug eluting stents has led to the development of new antiproliferative agents with alternative stent platforms and different drug carrier vehicles. Methods: The TEST (Tacrolimus Eluting STent) registry is a prospective, nonrandomized single-center registry in which 140 consecutive patients who underwent single- or multi-vessel percutaneous coronary intervention between February 2005 and August 2005 were enrolled. Results: The composite rate of major adverse cardiac events (MACE) at 22 months clinical follow-up was 40.9%. The rate of mortality, myocardial infarction, and target lesion revascularization (TLR) were 5.5%, 11%, and 31.5%, respectively. Angiographic follow-up at 8 months was achieved in 74% of patients; binary restenosis occurred in 39.4% of lesions. Most restenosis lesions (94.6%) had a diffuse pattern, while focal restenosis was observed in 5.4% of cases. Definite or probable stent thrombosis was observed in 2.4% of patients. Conclusions: The present prospective, nonrandomized, TEST registry indicated high MACE and restenosis rates, and thereby rather discouraging long-term outcomes with use of the Janus TES in an unselected “real world” population of patients who underwent single- or multi-vessel percutaneous coronary intervention. © 2009 Wiley-Liss, Inc.
تدمد:
1522-726X
الوصول الحر:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00db1da3bec0bdb6853ac6ba18f40a81Test https://pubmed.ncbi.nlm.nih.gov/19156897Test
حقوق:
CLOSED
رقم الانضمام:
edsair.doi.dedup.....00db1da3bec0bdb6853ac6ba18f40a81
قاعدة البيانات:
OpenAIRE
