المؤلفون: Abozaid MA, Abdalla A

المصدر: Clinical Ophthalmology, Vol Volume 14, Pp 473-480 (2020)

مصطلحات موضوعية: alpins method, astigmatic correction in keratoconus, kerarings, vector analysis, Ophthalmology, RE1-994

الوصف: Mortada Ahmed Abozaid,1 Abdelsalam Abdalla2 1Faculty of Medicine, Sohag University, Sohag, Egypt; 2Faculty of Medicine, Assiut University, Assiut, EgyptCorrespondence: Mortada Ahmed AbozaidOphthalmology Department, Faculty of Medicine, Sohag University, Sohag, EgyptTel +20 932 309 244Fax +20 932 325 531Email mourtada_abdelaal@med.sohag.edu.egPurpose: To analyze astigmatic changes after intrastromal corneal ring segments (ICRSs) implantation accompanied by corneal collagen cross-linking (CXL) in keratoconic eyes using the Alpins vectorial method.Patients and Methods: Twenty-eight eyes of 18 patients with keratoconus were included in this retrospective non-comparative study. All patients had combined femtosecond laser-assisted Keraring implantation and CXL, and completed at least 2 years of follow-up. Both manifest and corneal astigmatic changes were analyzed using the Alpins vectorial parameters based on 3 vectors; target induced astigmatism (TIA), surgically induced astigmatism (SIA) and difference vector (DV).Results: Regarding analysis of manifest astigmatism, the TIA arithmetic mean was 5.22 D while the vector mean was 3.13 D Ax 173. The SIA arithmetic mean was 5.41 D while the vector mean was 2.38 D Ax 173. The DV arithmetic mean was 2.10 D while the vector mean was 0.75 D Ax 175. Regarding analysis of corneal astigmatism, the TIA arithmetic mean was 5.22 D while the vector mean was 3.13 D Ax 173. The SIA arithmetic mean was 5.23 D while the vector mean was 1.8 D Ax 12. The DV arithmetic mean was 4.28 D while the vector mean was 2.04 D Ax 157.Conclusion: Vector analysis of manifest and corneal astigmatism in keratoconic eyes with previous ICRS and CXL reveals more accuracy and predictability of manifest refraction in calculating SIA.Keywords: Alpins method, astigmatic correction in keratoconus, kerarings, vector analysis

وصف الملف: electronic resource

العلاقة: https://www.dovepress.com/vector-analysis-of-astigmatism-in-keratoconic-eyes-after-combined-intr-peer-reviewed-article-OPTHTest; https://doaj.org/toc/1177-5483Test

الوصول الحر: https://doaj.org/article/2448a1846a8943a58b6b4c320252c12fTest

المؤلفون: Abozaid MA, Hassan AAA, Abdalla A

المصدر: Clinical Ophthalmology, Vol Volume 13, Pp 2151-2157 (2019)

مصطلحات موضوعية: accelerated transepithelial cross-linking, keraring, pediatric keratoconus, spring catarrh., Ophthalmology, RE1-994

الوصف: Mortada Ahmed Abozaid,1 Amin Abo-Ali Hassan,1 Abdelsalam Abdalla2 1Department of Ophthalmology, Faculty of Medicine, Sohag University, Sohag, Egypt; 2Department of Ophthalmology, Faculty of Medicine, Assiut University, Assiut, EgyptCorrespondence: Mortada Ahmed AbozaidOphthalmology Department, Faculty of Medicine, Sohag University, Sohag, EgyptTel +20932309244Fax +20932325531Email mourtada_abdelaal@med.sohag.edu.egPurpose: To assess the 3-year safety and efficacy of femtosecond laser-assisted intrastromal corneal ring segments’ (ICRS) implantation followed or accompanied by transepithelial accelerated corneal collagen cross-linking (TE-ACXL) as a treatment of keratoconus in children with vernal keratoconjunctivitis (VKC).Patients and methods: Fifty two eyes of 28 children with keratoconus and vernal VKC were included in this study. Cases were divided into 2 groups; the first group had been treated with femtosecond laser-assisted ICRS (Keraring) implantation accompanied or followed by TE-ACXL, while the second group had been treated by TE-ACXL only and all cases completed a follow-up period of 3 years.Results: In group 1: the mean uncorrected (UCVA) and best-corrected (BCVA) visual acuity, spherical equivalent, K-max and Q-value improved markedly from 0.97 ± 0.19, 0.67 ± 0.18, −8.75 ± 4.55, 60.41 ± 4.98, and −1.18 ± 0.54 preoperatively to 0.61 ± 0.27, 0.39±0.21, −3.25 ± 3.56, 55.22 ± 5.72, and −0.44 ± 0.68 postoperatively respectively. While in group 2: the preoperative mean UCVA, BCVA, spherical equivalent, K-max and Q-values were 0.68 ± 0.28, 0.38 ± 0.24, −2.84 ± 2.59, 50.29 ± 4.04, and-0.58 ± 0.23 respectively while their corresponding postoperative values were 0.58 ± 0.34, 0.19 ± 0.17, −2.35 ± 2.07, 49.58 ± 3.26, and −0.57 ± 0.25. Only one case in group 1 required repeat cross-linking.Conclusion: Although the long-term safety and efficacy of femtosecond laser-assisted ICRS implantation accompanied or followed by TE-ACXL in children with keratoconus and VKC is high, some cases still may need repeat cross-linking.Keywords: accelerated transepithelial cross-linking, Keraring, pediatric keratoconus, spring catarrh

وصف الملف: electronic resource

العلاقة: https://www.dovepress.com/intrastromal-corneal-ring-segments-implantation-and-corneal-cross-link-peer-reviewed-article-OPTHTest; https://doaj.org/toc/1177-5483Test

الوصول الحر: https://doaj.org/article/f22aee790c974874bd949e06321d81caTest

المؤلفون: Abozaid MA

المصدر: Clinical Ophthalmology, Vol Volume 11, Pp 1891-1895 (2017)

مصطلحات موضوعية: Corneal Cross-Linking, Keraring Implantation, Pediatric Keratoconus, Vernal Keratoconjunctivitis., Ophthalmology, RE1-994

الوصف: Mortada A Abozaid Ophthalmology Department, Faculty of Medicine, Sohag University, Sohag, Egypt Purpose: The purpose of this study was to assess the safety and efficacy of femtosecond laser-assisted Keraring implantation followed by transepithelial accelerated corneal collagen cross-linking (CXL) for the treatment of keratoconus in children with vernal keratoconjunctivitis (VKC).Study design: This is a prospective interventional non-comparative case series.Patients and methods: Eighteen eyes of 11 children with keratoconus and VKC were included in this study. All the cases were treated with femtosecond laser-assisted Keraring implantation followed after 2 weeks by transepithelial accelerated CXL, and the patients were followed up for 1 year.Results: The preoperative mean uncorrected visual acuity (UCVA) was 1.01±0.2 (logMAR), whereas the postoperative mean UCVA was 0.6±0.2. The preoperative mean best-corrected visual acuity (BCVA) was 0.6±0.1, whereas the postoperative mean BCVA was 0.40±0.2. The preoperative average keratometry was 50.3±2.7 D, whereas the postoperative average keratometry was 45.8±3.1 D. Conclusion: The results of this study suggest that femtosecond laser-assisted Keraring implantation followed by CXL is safe and effective in the management of keratoconus in children with VKC. However, studies with a longer follow-up period are needed. Keywords: cross-linking plus, intrastromal corneal ring segments, pediatric keratoconus, spring catarrh

وصف الملف: electronic resource

العلاقة: https://www.dovepress.com/sequential-keraring-implantation-and-corneal-cross-linking-for-the-tre-peer-reviewed-article-OPTHTest; https://doaj.org/toc/1177-5483Test

الوصول الحر: https://doaj.org/article/2e7f47eb683d43f1b4bfcc824eaa8964Test

المؤلفون: Alsmman AH, Radwan G, Abozaid MA, Mohammed UA, Abd Elhaliem NG

المصدر: Clinical Ophthalmology, Vol Volume 11, Pp 493-501 (2017)

مصطلحات موضوعية: subconjunctival bevacizumab, subconjunctival mitomycin C, histolog-ical changes, primary pterygium, CD31., Ophthalmology, RE1-994

الوصف: Alahmady Hamad Alsmman,1 Gamal Radwan,1 Mortada Ahmed Abozaid,1 Usama Ali Mohammed,1 Nesreen Gamal Abd Elhaleim2 1Department of Ophthalmology, 2Department of Histology, Sohag Faculty of Medicine, Sohag University, Sohag, Egypt Purpose: The aim of this study was to detect the clinical and histological effects of preoperative subconjunctival injection of both bevacizumab and mitomycin C (MMC) 1 month before the surgical excision of primary pterygium using a bare sclera technique. Patients and methods: A total of 20 patients with primary pterygium underwent subconjunctival combined injection of 0.1 mL of MMC (0.1 mg/mL) and 0.1 mL of bevacizumab (1.25 mg/0.1 mL) 1 month before bare sclera excision of the pterygium. The excised pterygium tissues were examined histologically and immunohistologically by CD31 staining, and the patients were followed up clinically for at least 2 years. The excised pterygia of two patients without preoperative injection were used for histological comparison. Results: Clinically, there were no intraoperative or postoperative complications. No recurrence was noted during the follow-up period. Histologically, the previously injected pterygia showed a decreased number of epithelial cells and stromal fibroblasts. The latter were rounded or oval and swollen rather than spindle shaped, and some were degenerating or apoptotic. Collagen and elastic fibers were degenerated, distorted, and decreased in density, while blood capillaries were obliterated. There was a significant decrease in CD31-positive cells in previously injected pterygia. Conclusion: Preoperative subpterygium combined injection of bevacizumab and MMC is safe and effective in reducing the postoperative recurrence of primary pterygium. Histological and immunohistological changes in the form of decreased fibrovascular activity and degeneration of the extracellular matrix and nerve axons were noted. Keywords: subconjunctival bevacizumab, subconjunctival mitomycin C, histological changes, primary pterygium, CD31

وصف الملف: electronic resource

العلاقة: https://www.dovepress.com/preoperative-subconjunctival-combined-injection-of-bevacizumab-and-mit-peer-reviewed-article-OPTHTest; https://doaj.org/toc/1177-5483Test

الوصول الحر: https://doaj.org/article/c47a06f8c101479ca218918fa60a1633Test