دورية أكاديمية
Tracheostomy management in patients with severe acute respiratory distress syndrome receiving extracorporeal membrane oxygenation: an International Multicenter Retrospective Study
| العنوان: | Tracheostomy management in patients with severe acute respiratory distress syndrome receiving extracorporeal membrane oxygenation: an International Multicenter Retrospective Study |
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| المؤلفون: | Schmidt, Matthieu, Fisser, Christoph, Martucci, Gennaro, Abrams, Darryl, Frapard, Thomas, Popugaev, Konstantin, Arcadipane, Antonio, Bromberger, Bianca, Lino, Giovanni, Serra, Alexis, Rozencwajg, Sacha, Lubnow, Matthias, Petrikov, Sergey, Mueller, Thomas, Combes, Alain, Pham, Tài, Brodie, Daniel |
| المساهمون: | Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Research Unit on Cardiovascular and Metabolic Diseases (ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Institut de Cardiométabolisme et Nutrition = Institute of Cardiometabolism and Nutrition CHU Pitié Salpêtrière (IHU ICAN), CHU Pitié-Salpêtrière AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-CHU Pitié-Salpêtrière AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), University Hospital Regensburg, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS), Columbia University New York, New York Presbyterian Hospital, Groupe de recherche clinique CARMAS (Cardiovascular and Respiratory Manifestations of Acute lung injury and Sepsis) (CARMAS), Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-CHU Henri Mondor Créteil, Centre de recherche en épidémiologie et santé des populations (CESP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, Université de Versailles Saint-Quentin-en-Yvelines - UFR Sciences de la santé Simone Veil (UVSQ Santé), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ) |
| المصدر: | ISSN: 1364-8535. |
| بيانات النشر: | HAL CCSD BioMed Central |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | ECMO, Acute respiratory distress syndrome, Mechanical ventilation, Tracheostomy, Bleeding, Outcome, [SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract, [SDV.MHEP.CHI]Life Sciences [q-bio]/Human health and pathology/Surgery |
| الوصف: | International audience ; Background: Current practices regarding tracheostomy in patients treated with extracorporeal membrane oxygenation (ECMO) for acute respiratory distress syndrome are unknown. Our objectives were to assess the prevalence and the association between the timing of tracheostomy (during or after ECMO weaning) and related complications, sedative, and analgesic use.Methods: International, multicenter, retrospective study in four large volume ECMO centers during a 9-year period.Results: Of the 1,168 patients treated with ECMO for severe ARDS (age 48 ± 16 years, 76% male, SAPS II score 51 ± 18) during the enrollment period, 353 (30%) and 177 (15%) underwent tracheostomy placement during or after ECMO, respectively. Severe complications were uncommon in both groups. Local bleeding within 24 h of tracheostomy was four times more frequent during ECMO (25 vs 7% after ECMO, p < 0.01). Cumulative sedative consumption decreased more rapidly after the procedure with sedative doses almost negligible 48–72 h later, when tracheostomy was performed after ECMO decannulation (p < 0.01). A significantly increased level of consciousness was observed within 72 h after tracheostomy in the “after ECMO” group, whereas it was unchanged in the “during-ECMO” group.Conclusion: In contrast to patients undergoing tracheostomy after ECMO decannulation, tracheostomy during ECMO was neither associated with a decrease in sedation and analgesia levels nor with an increase in the level of consciousness. This finding together with a higher risk of local bleeding in the days following the procedure reinforces the need for a case-by-case discussion on the balance between risks and benefits of tracheotomy when performed during ECMO. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/34233748; hal-03284011; https://hal.sorbonne-universite.fr/hal-03284011Test; https://hal.sorbonne-universite.fr/hal-03284011/documentTest; https://hal.sorbonne-universite.fr/hal-03284011/file/s13054-021-03649-8.pdfTest; PUBMED: 34233748 |
| DOI: | 10.1186/s13054-021-03649-8 |
| الإتاحة: | https://doi.org/10.1186/s13054-021-03649-8Test https://hal.sorbonne-universite.fr/hal-03284011Test https://hal.sorbonne-universite.fr/hal-03284011/documentTest https://hal.sorbonne-universite.fr/hal-03284011/file/s13054-021-03649-8.pdfTest |
| حقوق: | http://creativecommons.org/licenses/byTest/ ; info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.EF5D20D4 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1186/s13054-021-03649-8 |
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