المؤلفون: van Rheenen, Wouter, van der Spek, Rick AA, Bakker, Mark K, van Vugt, Joke JFA, Hop, Paul J, Zwamborn, Ramona AJ, de Klein, Niek, Westra, Harm-Jan, Bakker, Olivier B, Deelen, Patrick, Shireby, Gemma, Hannon, Eilis, Moisse, Matthieu, Baird, Denis, Restuadi, Restuadi, Dolzhenko, Egor, Dekker, Annelot M, Gawor, Klara, Westeneng, Henk-Jan, Tazelaar, Gijs HP, van Eijk, Kristel R, Kooyman, Maarten, Byrne, Ross P, Doherty, Mark, Heverin, Mark, Al Khleifat, Ahmad, Iacoangeli, Alfredo, Shatunov, Aleksey, Ticozzi, Nicola, Cooper-Knock, Johnathan, Smith, Bradley N, Gromicho, Marta, Chandran, Siddharthan, Pal, Suvankar, Morrison, Karen E, Shaw, Pamela J, Hardy, John, Orrell, Richard W, Sendtner, Michael, Meyer, Thomas, Başak, Nazli, van der Kooi, Anneke J, Ratti, Antonia, Fogh, Isabella, Gellera, Cinzia, Lauria, Giuseppe, Corti, Stefania, Cereda, Cristina, Sproviero, Daisy, D’Alfonso, Sandra, Sorarù, Gianni, Siciliano, Gabriele, Filosto, Massimiliano, Padovani, Alessandro, Chiò, Adriano, Calvo, Andrea, Moglia, Cristina, Brunetti, Maura, Canosa, Antonio, Grassano, Maurizio, Beghi, Ettore, Pupillo, Elisabetta, Logroscino, Giancarlo, Nefussy, Beatrice, Osmanovic, Alma, Nordin, Angelica, Lerner, Yossef, Zabari, Michal, Gotkine, Marc, Baloh, Robert H, Bell, Shaughn, Vourc’h, Patrick, Corcia, Philippe, Couratier, Philippe, Millecamps, Stéphanie, Meininger, Vincent, Salachas, François, Mora Pardina, Jesus S, Assialioui, Abdelilah, Rojas-García, Ricardo, Dion, Patrick A, Ross, Jay P, Ludolph, Albert C, Weishaupt, Jochen H, Brenner, David, Freischmidt, Axel, Bensimon, Gilbert, Brice, Alexis, Durr, Alexandra, Payan, Christine AM, Saker-Delye, Safa, Wood, Nicholas W, Topp, Simon, Rademakers, Rosa, Tittmann, Lukas, Lieb, Wolfgang, Franke, Andre, Ripke, Stephan, Braun, Alice, Kraft, Julia

المصدر: Nature Genetics. 53(12)

مصطلحات موضوعية: Human Genome, Neurodegenerative, Clinical Research, Rare Diseases, Prevention, ALS, Neurosciences, Genetics, Brain Disorders, Aetiology, 2.1 Biological and endogenous factors, Neurological, Amyotrophic Lateral Sclerosis, Brain, Cholesterol, Disease Progression, Female, Genome-Wide Association Study, Glutamine, Humans, Male, Mendelian Randomization Analysis, Microsatellite Repeats, Mutation, Neurodegenerative Diseases, Neurons, Quantitative Trait Loci, RNA-Seq, Risk Factors, SLALOM Consortium, PARALS Consortium, SLAGEN Consortium, SLAP Consortium, Biological Sciences, Medical and Health Sciences, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/07c2z7v3Test

المؤلفون: Rosenthal, Sara Brin, Liu, Xiao, Ganguly, Souradipta, Dhar, Debanjan, Pasillas, Martina P, Ricciardelli, Eugenia, Li, Rick Z, Troutman, Ty D, Kisseleva, Tatiana, Glass, Christopher K, Brenner, David A

المصدر: Hepatology. 74(2)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Biotechnology, Digestive Diseases, Liver Disease, Aetiology, 2.1 Biological and endogenous factors, Animals, Cell Cycle Proteins, Cells, Cultured, Diet, Western, Disease Models, Animal, Gene Regulatory Networks, Genetic Heterogeneity, Hepatic Stellate Cells, Humans, Liver, Male, Mice, Mice, Transgenic, Mutation, Myofibroblasts, Non-alcoholic Fatty Liver Disease, Primary Cell Culture, RNA-Seq, Single-Cell Analysis, Medical Biochemistry and Metabolomics, Clinical Sciences, Immunology, Gastroenterology & Hepatology, Clinical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/5kh7t0ffTest

المؤلفون: Shuryak, Igor, Sachs, Rainer K, Brenner, David J

المصدر: Scientific Reports. 11(1)

مصطلحات موضوعية: Physical Sciences, Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Cancer, Animals, Carcinogenesis, Cell Transformation, Neoplastic, Cosmic Radiation, Gamma Rays, Humans, Linear Energy Transfer, Male, Mice, Neoplasms, Radiation-Induced, Protons, Relative Biological Effectiveness, Space Flight

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/5qh5d6b0Test

المؤلفون: Rady, Brian, Nishio, Takahiro, Dhar, Debanjan, Liu, Xiao, Erion, Mark, Kisseleva, Tatiana, Brenner, David A, Pocai, Alessandro

المصدر: PLOS ONE. 16(12)

مصطلحات موضوعية: Biological Sciences, Biomedical and Clinical Sciences, Genetics, Liver Disease, Digestive Diseases, Chronic Liver Disease and Cirrhosis, Aetiology, 2.1 Biological and endogenous factors, Oral and gastrointestinal, Adult, Aged, Cells, Cultured, Down-Regulation, Female, Gene Expression Regulation, Hepatic Stellate Cells, Humans, Lipase, Lipid Droplets, Male, Membrane Proteins, Middle Aged, Mutation, Missense, Non-alcoholic Fatty Liver Disease, Polymorphism, Single Nucleotide, Primary Cell Culture, Transforming Growth Factor beta, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/28f8n2mvTest

المؤلفون: Duan, Yi, Chu, Huikuan, Brandl, Katharina, Jiang, Lu, Zeng, Suling, Meshgin, Nairika, Papachristoforou, Eleni, Argemi, Josepmaria, Mendes, Beatriz G, Wang, Yanhan, Su, Hua, Sun, Weizhong, Llorente, Cristina, Hendrikx, Tim, Liu, Xiao, Hosseini, Mojgan, Kisseleva, Tatiana, Brenner, David A, Bataller, Ramon, Ramachandran, Prakash, Karin, Michael, Fu, Wenxian, Schnabl, Bernd

المصدر: Nature Communications. 12(1)

مصطلحات موضوعية: Chronic Liver Disease and Cirrhosis, Substance Misuse, Digestive Diseases, Infectious Diseases, Liver Disease, Alcoholism, Alcohol Use and Health, Aetiology, 2.1 Biological and endogenous factors, Oral and gastrointestinal, Inflammatory and immune system, Good Health and Well Being, Animals, Bacterial Translocation, Complement C3b, Enterococcus faecalis, Ethanol, Female, Gastrointestinal Tract, Gram-Positive Bacterial Infections, Humans, Liver, Liver Diseases, Alcoholic, Macrophages, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Receptors, Complement, Receptors, Complement 3b

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/6nv9c3wwTest

المؤلفون: Jiang, Lu, Lang, Sonja, Duan, Yi, Zhang, Xinlian, Gao, Bei, Chopyk, Jessica, Schwanemann, Leila K, Ventura‐Cots, Meritxell, Bataller, Ramon, Bosques‐Padilla, Francisco, Verna, Elizabeth C, Abraldes, Juan G, Brown, Robert S, Vargas, Victor, Altamirano, Jose, Caballería, Juan, Shawcross, Debbie L, Ho, Samuel B, Louvet, Alexandre, Lucey, Michael R, Mathurin, Philippe, Garcia‐Tsao, Guadalupe, Kisseleva, Tatiana, Brenner, David A, Tu, Xin M, Stärkel, Peter, Pride, David, Fouts, Derrick E, Schnabl, Bernd

المصدر: Hepatology. 72(6)

مصطلحات موضوعية: Clinical Research, Hepatitis, Substance Misuse, Alcoholism, Alcohol Use and Health, Chronic Liver Disease and Cirrhosis, Digestive Diseases, Liver Disease, Infection, Oral and gastrointestinal, Good Health and Well Being, Adult, Aged, Animals, Bacteriophages, Case-Control Studies, DNA, Viral, End Stage Liver Disease, Feces, Female, Hepatitis, Alcoholic, Herpesviridae, Humans, Intestinal Mucosa, Liver, Liver Cirrhosis, Male, Metagenomics, Middle Aged, Parvoviridae, RNA, Viral, Severity of Illness Index, Survival Rate, Virome, Medical Biochemistry and Metabolomics, Clinical Sciences, Immunology, Gastroenterology & Hepatology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/1xj7d1xrTest

المؤلفون: Oh, Tae Gyu, Kim, Susy M, Caussy, Cyrielle, Fu, Ting, Guo, Jian, Bassirian, Shirin, Singh, Seema, Madamba, Egbert V, Bettencourt, Ricki, Richards, Lisa, Yu, Ruth T, Atkins, Annette R, Huan, Tao, Brenner, David A, Sirlin, Claude B, Downes, Michael, Evans, Ronald M, Loomba, Rohit

المصدر: Cell Metabolism. 32(5)

مصطلحات موضوعية: Microbiology, Biological Sciences, Biomedical and Clinical Sciences, Medical Biochemistry and Metabolomics, Digestive Diseases, Human Genome, Hepatitis, Clinical Research, Liver Disease, Chronic Liver Disease and Cirrhosis, Genetics, Aetiology, 2.1 Biological and endogenous factors, Oral and gastrointestinal, Adult, Aged, Aged, 80 and over, Aspartate Aminotransferases, Cohort Studies, Feces, Female, Gastrointestinal Microbiome, Humans, Liver Cirrhosis, Male, Metabolome, Metagenome, Middle Aged, Non-alcoholic Fatty Liver Disease, Serum Albumin, Human, NAFLD, NASH, biomarker, cirrhosis, fatty liver, liver fibrosis, metabolomics, metagenomics, microbiome, microbiota, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, Biochemistry and Cell Biology, Endocrinology & Metabolism, Biochemistry and cell biology, Medical biochemistry and metabolomics

الوصول الحر: https://escholarship.org/uc/item/18z0w4d5Test

المؤلفون: Riopel, Matthew, Moon, Jae-Su, Bandyopadhyay, Gautam K, You, Seohee, Lam, Kevin, Liu, Xiao, Kisseleva, Tatiana, Brenner, David, Lee, Yun Sok

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Nutrition, Digestive Diseases, Diabetes, Liver Disease, Obesity, 1.1 Normal biological development and functioning, Aetiology, Underpinning research, Development of treatments and therapeutic interventions, 2.1 Biological and endogenous factors, 5.1 Pharmaceuticals, Metabolic and endocrine, Animals, Basic Helix-Loop-Helix Transcription Factors, Glucagon, Glucose, Hepatocytes, Humans, Insulin, Insulin Resistance, Liver, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Prolyl Hydroxylases, Prolyl-Hydroxylase Inhibitors, Signal Transduction, Obesity-induced glucose intolerance, Type 2 diabetes, Liver glucagon sensitivity, Prolyl hydroxylase domain (PHD) enzymes, Physiology, Biochemistry and cell biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/6855g2w5Test
https://escholarship.org/content/qt6855g2w5/qt6855g2w5.pdfTest

المؤلفون: Pizza, Vincenzo, Antonini, Paola, Marino, Rosella, D'Arena, Giovanni, Lucibello, Serena Grazia, Rizzo, Marianna, Brenner, David A, Jeste, Dilip V, Somma, Salvatore Di

المصدر: Medicina (Kaunas, Lithuania). 56(5)

مصطلحات موضوعية: Humans, Cross-Sectional Studies, Pilot Projects, Neuropsychological Tests, Aging, Longevity, Aged, 80 and over, Home Care Services, Italy, Female, Male, Cognitive Dysfunction, Cilento Region, cognitive health, lifestyle, longevity, General & Internal Medicine

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/25k4t84rTest

المؤلفون: Ma, Hsiao-Yen, Yamamoto, Gen, Xu, Jun, Liu, Xiao, Karin, Daniel, Kim, Ju Youn, Alexandrov, Ludmil B, Koyama, Yukinori, Nishio, Takahiro, Benner, Chris, Heinz, Sven, Rosenthal, Sara B, Liang, Shuang, Sun, Mengxi, Karin, Gabriel, Zhao, Peng, Brodt, Pnina, Mckillop, Iain H, Quehenberger, Oswald, Dennis, Ed, Saltiel, Alan, Tsukamoto, Hidekazu, Gao, Bin, Karin, Michael, Brenner, David A, Kisseleva, Tatiana

المصدر: Journal of Hepatology. 72(5)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Immunology, Liver Disease, Alcoholism, Alcohol Use and Health, Rare Diseases, Nutrition, Cancer, Digestive Diseases, Chronic Liver Disease and Cirrhosis, Substance Misuse, Liver Cancer, 2.1 Biological and endogenous factors, Aetiology, Oral and gastrointestinal, Inflammatory and immune system, Good Health and Well Being, Animals, Carcinogenesis, Carcinoma, Hepatocellular, Disease Models, Animal, Ethanol, Gene Deletion, Hepatocytes, Humans, Interleukin-17, Kupffer Cells, Liver Cirrhosis, Liver Diseases, Alcoholic, Liver Neoplasms, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Receptors, Interleukin-17, Signal Transduction, Transcriptome, Alcoholic liver disease, ALD, Cholesterol synthesis, Fibrosis, Hepatocellular carcinoma, HCC, IL-17 signaling, Inflammation, Mutational signatures, Clinical Sciences, Public Health and Health Services, Gastroenterology & Hepatology, Clinical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/324064jnTest