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المؤلفون: Julia Bier, Joanne Smart, Melanie Wong, Gulbu Uzel, Henry Brigden, Isabelle Meyts, Luigi D. Notarangelo, Amanda J. Russell, Lucinda J. Berglund, Katherine J. L. Jackson, Stuart G. Tangye, Joanne H. Reed, Sharon Choo, Paul Gray, Kaan Boztug, Danielle T. Avery, Stefano Volpi, Christopher C. Goodnow, Robert Brink, Helen Lenthall, Michael O'Sullivan, Theresa Cole, Anthony Lau, Peter Hsu, Elissa K. Deenick
المصدر: The Journal of Experimental Medicine
مصطلحات موضوعية: Male, Class I Phosphatidylinositol 3-Kinases, Plasma Cells, Immunology, Autoimmunity, Mice, Transgenic, Biology, medicine.disease_cause, Autoantigens, Article, Mice, Immune Tolerance, medicine, Animals, Humans, Immunology and Allergy, Research Articles, B cell, Autoantibodies, Autoantibody, Germinal center, Peripheral tolerance, Germinal Center, Mice, Inbred C57BL, medicine.anatomical_structure, Immunoglobulin M, P110δ, Gain of Function Mutation, Antibody Formation, biology.protein, Female, Antibody, Signal Transduction
وصف الملف: Print
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06a467e437cb439bb2cab65f6c5b4da8Test
http://hdl.handle.net/11567/1024151Test -
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المؤلفون: Helen Lenthall, Isabelle Meyts, Robert Brink, Kathryn Payne, Christoph Burkhart, Kaan Boztug, Wei Shi, Elise French, Melanie Wong, Lynn M. Corcoran, Gulbu Uzel, William A. Sewell, Michael O'Sullivan, Lucinda J. Berglund, Danielle T. Avery, Alisa Kane, David Zahra, Paul Gray, Danyal Butt, Tri Giang Phan, Anthony Lau, Sharon Choo, Stuart G. Tangye, Henry Brigden, Peter Hsu, Elissa K. Deenick, Jana R. Hermes, Theresa Cole, Tina Nguyen, Michael Elliott, Cindy S. Ma, Julia Bier, Steven M. Holland, Akira Nguyen
المصدر: The Journal of Experimental Medicine
مصطلحات موضوعية: 0301 basic medicine, Cellular differentiation, Antibody Affinity, PI3 KINASE, Research & Experimental Medicine, PHOSPHOINOSITIDE 3-KINASE, medicine.disease_cause, CLASS-SWITCH RECOMBINATION, Mice, Phosphatidylinositol 3-Kinases, HUMAN IMMUNODEFICIENCY, SECRETING CELLS, Immunology and Allergy, Child, Research Articles, B-Lymphocytes, Mutation, biology, Cell Differentiation, Cytidine deaminase, ANTIBODY-PRODUCTION, 3. Good health, Cell biology, Phenotype, medicine.anatomical_structure, ANTIGEN AFFINITY, Medicine, Research & Experimental, Gain of Function Mutation, Models, Animal, PHOSPHATIDYLINOSITOL 3-KINASE, Antibody, Life Sciences & Biomedicine, Signal Transduction, Class I Phosphatidylinositol 3-Kinases, Plasma Cells, Immunology, Immunoglobulins, Bone Marrow Cells, Article, 03 medical and health sciences, Germline mutation, Immune system, medicine, 3-KINASE DELTA SYNDROME, Animals, Humans, Germ-Line Mutation, B cell, Cell Proliferation, P85-ALPHA SUBUNIT, Science & Technology, Interleukins, biochemical phenomena, metabolism, and nutrition, Immunoglobulin Class Switching, 030104 developmental biology, Immunoglobulin class switching, biology.protein
وصف الملف: Print-Electronic
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb0e6265bfc33cb2d8fc21980955e4a9Test
https://doi.org/10.1084/jem.20180010Test -
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المؤلفون: Danielle T. Avery, Rita Beier, Annaliesse Blincoe, Rubén Martínez-Barricarte, David A. Fulcher, Jamila El Baghdadi, Aydan Ikinciogullari, Sara Sebnem Kilic, Yoshiyuki Minegishi, Geetha Rao, Capucine Picard, Melanie Wong, Kathryn Payne, Michael Stormon, Polina Stepensky, Gulbu Uzel, Paul Gray, Stephen Adelstein, Martyn A. French, Masao Kobayashi, Matthew C. Cook, Jean-Laurent Casanova, Klaus Warnatz, Stuart G. Tangye, Bodo Grimbacher, Aziz Bousfiha, Stéphanie Boisson-Dupuis, Natalie Wong, Patrick O’Young, Tri Giang Phan, Akira Nguyen, James Torpy, Michael Elliott, Cindy S. Ma, John B. Ziegler, Steven M. Holland, Peter Hsu, Elissa K. Deenick, Satoshi Okada, Jacinta Bustamante, Sophie Hambleton, Dianne E. Campbell, Anne Puel, Peter D. Arkwright, Kaan Boztug, Nic Robertson
المساهمون: Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Anabilim Dalı., Kılıç, Sara Şebnem, AAH-1658-2021
المصدر: The Journal of Experimental Medicine
Ma, C S, Wong, N, Rao, G, Nguyen, A, Avery, D T, Payne, K, Torpy, J, O'Young, P, Deenick, E, Bustamante, J, Puel, A, Okada, S, Kobayashi, M, Martinez-Barricarte, R, Elliott, M, Kilic, S S, Baghdadi, J E, Minegishi, Y, Bousfiha, A, Robertson, N, Hambleton, S, Arkwright, P, French, M, Blincoe, A K, Hsu, P, Campbell, D E, Stormon, M O, Wong, M, Adelstein, S, Fulcher, D A, Cook, M C, Stepensky, P, Boztug, K, Beier, R, Ikincioğullari, A, Ziegler, J B, Gray, P, Picard, C, Boisson-Dupuis, S, Phan, T G, Grimbacher, B, Warnatz, K, Holland, S M, Uzel, G, Casanova, J L & Tangye, S G 2016, ' Unique and shared signaling pathways cooperate to regulate the differentiation of human CD4 + T cells into distinct effector subsets ', Journal of Experimental Medicine, vol. 213, no. 8, pp. 1589-1608 . https://doi.org/10.1084/jem.20151467Testمصطلحات موضوعية: Male, 0301 basic medicine, Interleukin 12 receptor beta1, STAT6 protein, Cellular differentiation, Immune deficiency, Medizin, Follicular-helper-cells, STAT1 gene, Ectodermal dysplasia, medicine.disease_cause, STAT1 protein, human, Gene, Essential modulator mutation, Differentiation antigen, Chronic mucocutaneous candidiasis, Interleukin 10, Hyper-ige syndrome, Icos deficiency, STAT4 protein, Gain of function mutation, Immunology and Allergy, Research Articles, Priority journal, Th17 cell, Mutation, Th1 cell, Effector, Cell Differentiation, Interleukin-10, 3. Good health, Cell biology, Lymphocyte differentiation, STAT1 Transcription Factor, medicine.anatomical_structure, Intracellular signaling, Effector cell, Female, BCL6 expression, Signal transduction, CD4 antigen, Protein kinase TYK2, Human, STAT3 Transcription Factor, Cell subpopulation, T cell, IL10 protein, mouse, Immunology, Helper Cell, Germinal Center, Tfh Cell, Biology, Gamma interferon receptor, STAT3 gene, Article, Common variable immunodeficiency, Antibody-responses, Immunomodulation, 03 medical and health sciences, Protein phosphorylation, Th2 Cells, Immune system, STAT3 protein, Antigen, STAT1 protein, Genetics, medicine, Humans, Th0 cell, Medicine, research & experimental, Cytokine release, Gamma interferon, Infection sensitivity, L kappa B kinase gamma, CD4+ T lymphocyte, Immunoregulation, In vitro study, Th1 Cells, Interleukin 21 receptor, Antigens, Differentiation, Humoral immunity, Interleukin 21, Th2 cell, 030104 developmental biology, Human cell, Th17 Cells, Cytology, IL-10 production, Controlled study
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dee2b2bc49c951ae46185f318cb05abbTest
http://repo.lib.tokushima-u.ac.jp/115511Test