المؤلفون: Mansour Khalaf, Serdar Öztürk, Selim Badur, Debasish Saha, Fayssal M. Farahat, Atef M. Shibl, Mona A Al Dabbagh

المصدر: Infectious Diseases and Therapy

مصطلحات موضوعية: Microbiology (medical), medicine.medical_specialty, Epidemiology, Kingdom of Saudi Arabia, Population, Bacterial meningitis, Disease, Review, Mass gathering, Neisseria meningitidis, Meningococcal disease, Environmental health, Health care, Hajj, medicine, education, education.field_of_study, Surveillance, business.industry, Outbreaks, Outbreak, medicine.disease, Infectious Diseases, business

الوصف: Reducing invasive meningococcal disease (IMD) through MenACWY immunization is a critical healthcare strategy in the Kingdom of Saudi Arabia (KSA). Robust IMD surveillance is essential to help assess the need for additional immunization initiatives in target populations. This is particularly important in KSA, where mass gatherings accompanying Hajj/Umrah pilgrimages have been associated with IMD outbreaks within the local KSA population, and subsequent intercontinental spread via returning pilgrims. This narrative review of the published literature describes the changing epidemiology of IMD in KSA to provide a perspective on the impact of current immunization strategies and potential gaps. As recent published surveillance data are lacking, we also evaluated publicly reported data from the KSA Ministry of Health (MoH) for 2012–2019 to inform more recent IMD trends. Between 1995 and 2011, national surveillance data indicate that 1103 IMD cases were reported in KSA: 60% in 2000–2001, involving two (mainly MenW) outbreaks involving KSA citizens/residents and pilgrims focused in Mecca and Medina. Across 2002–2011, 184 cases of IMD were reported, with a higher proportion occurring in KSA citizens/residents, and with less focus within pilgrimage centers than apparent in previous years. Our analysis of MoH data found that, between 2012 and 2019, 44 IMD cases were reported, all in KSA citizens/residents, and chiefly in children or infants. No pilgrimage-associated outbreaks have occurred since 2001. Serogroup data were available for 62.5% of all cases for 2002–2011; MenW (40.0%), MenA (35.7%), and MenB (16.5%). Serogroup data for 2012–2019 remain incompletely reported, and the existing surveillance system could be improved, as some element of underestimation/underreporting of IMD may exist. While existing MenACWY immunization strategies for KSA citizens/residents and visiting pilgrims have been successful in reducing IMD due to specific serogroups, disease due to MenB remains a potential risk, and additional immunization strategies should be considered. Supplementary Information The online version contains supplementary material available at 10.1007/s40121-021-00467-x.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d0c54bb4dfa6ad8f3bc3966cfd67801Test
http://europepmc.org/articles/PMC8363858Test

المؤلفون: Samar Mhimdi, Sondes Haddad-Boubaker, Amel Kechrid, Cyrine Fathallah, Aida Bouafsoun, Marwa Lakhal, Hanen Smaoui

المصدر: African Health Sciences

مصطلحات موضوعية: Serotype, DNA, Bacterial, Male, Pediatrics, medicine.medical_specialty, Tunisia, Bacterial meningitis, Neonatal age, Neisseria meningitidis, medicine.disease_cause, Real-Time Polymerase Chain Reaction, Meningitis, Bacterial, children, Epidemiology, Streptococcus pneumoniae, Medicine, Humans, Child, Cerebrospinal Fluid, business.industry, Haemophilus influenzae type b, Infant, Newborn, Infant, General Medicine, Articles, medicine.disease, bacterial infections and mycoses, Vaccination, Epidemiologic Studies, PCR, Pneumococcal vaccine, Child, Preschool, Population Surveillance, Female, Seasons, business, Meningitis

الوصف: Background: Since the 1990s, the epidemiology of bacterial meningitis worldwide has changed thanks to vaccination. In Tunisia, the main causative pathogens were Streptococcus pneumoniae, Neisseria meningitidis and Haemophilus influenzae serotype b (Hib). Only Hib vaccination was available during our study period. Objectives: We performed a laboratory case report based-study of suspected bacterial meningitis in Northern Tunisia from January 2014 to June 2017. Methods: CSF samples obtained from children beyond neonatal age with suspicion of meningitis were tested by two real time PCRs, targeting pneumococcus, meningococcus and Hib, and conventional methods. Results: Using real-time PCR, 63 were positive including ten supplementary cases compared to conventional methods. A general decrease of bacterial meningitis cases was demonstrated comparing to previous data. Pneumococcus was predominant (69.84%) followed by meningococcus (28.57%) and Hib (1.59%). The main serotypes were 14, 19F, 6B and 23F for pneumococcus and serogroup B for meningococcus. Most cases occurred during cold season and children under one year were the most affect- ed by bacterial meningitis. Conclusion: Our study suggests the predominance of pneumococcal cases. It may provide valuable data on meningitis epidemiology before the introduction of pneumococcal vaccine, which may be useful for future evaluation. Keywords: Bacterial meningitis; children; Tunisia; PCR.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57cb84e47d0e651f255f963d7229c3b5Test
http://europepmc.org/articles/PMC7751517Test

المؤلفون: Honoré Flavien Aké, Fernanda C. Lessa, Olivier Ronveaux, Xin Wang, Ado M Bwaka, Andre Bita, LeAnne M. Fox, Ryan T. Novak

المصدر: The Journal of Infectious Diseases

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Vaccine evaluation, Supplement Articles, Meningococcal Vaccines, Meningitis, Meningococcal, Neisseria meningitidis, Meningococcal disease, Mass Vaccination, Pneumococcal conjugate vaccine, 03 medical and health sciences, 0302 clinical medicine, Conjugate vaccine, Environmental health, Epidemiology, Outcome Assessment, Health Care, medicine, Immunology and Allergy, Humans, 030212 general & internal medicine, Africa South of the Sahara, meningococcal, business.industry, Immunization Programs, Public health, medicine.disease, Meningococcal Infections, 030104 developmental biology, Infectious Diseases, Population Surveillance, Africa, meningitis epidemics, surveillance, Bacterial meningitis, business, Meningitis, medicine.drug, NmC

الوصف: In sub-Saharan Africa, bacterial meningitis remains a significant public health problem, especially in the countries of the meningitis belt, where Neisseria meningitidis serogroup A historically caused large-scale epidemics. In 2014, MenAfriNet was established as a consortium of partners supporting strategic implementation of case-based meningitis surveillance to monitor meningitis epidemiology and impact of meningococcal serogroup A conjugate vaccine (MACV). MenAfriNet improved data quality through use of standardized tools, procedures, and laboratory diagnostics. MenAfriNet surveillance and study data provided evidence of ongoing MACV impact, characterized the burden of non-serogroup A meningococcal disease (including the emergence of a new epidemic clone of serogroup C), and documented the impact of pneumococcal conjugate vaccine. New vaccines and schedules have been proposed for future implementation to address the remaining burden of meningitis. To support the goals of “Defeating Meningitis by 2030,” MenAfriNet will continue to strengthen surveillance and support research and modeling to monitor the impact of these programs on meningitis burden in sub-Saharan Africa.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d66eac37474bc579072a072786253b1Test
http://europepmc.org/articles/PMC6822967Test

المؤلفون: Matanelle Salama, Ziva Amitai, Sarit Rahmani, Lea Valinsky, Rivka Sheffer, Laura Dardik, Joseph Jaffe, Eran Kopel, Irina Yuabov

المصدر: Vaccine. 37:6186-6191

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Adolescent, Tel aviv, 030231 tropical medicine, Population, Meningococcal Vaccines, Disease, Meningitis, Meningococcal, Neisseria meningitidis, Disease Outbreaks, Disease rates, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Sepsis, Epidemiology, medicine, Humans, 030212 general & internal medicine, Israel, Child, education, Aged, Aged, 80 and over, education.field_of_study, General Veterinary, General Immunology and Microbiology, business.industry, Incidence, Public Health, Environmental and Occupational Health, Infant, Middle Aged, Vaccine introduction, Infectious Diseases, Invasive meningococcal disease, Child, Preschool, Molecular Medicine, Female, Bacterial meningitis, business, Multilocus Sequence Typing, Demography

الوصف: Invasive meningococcal disease (IMD) is one of the leading causes of bacterial meningitis and septicemia in Israel. The purpose of the study was to describe the IMD in the Tel Aviv District and to identify specific populations who could benefit from vaccine introduction. In the Tel Aviv District, the incidence rates ranged from 0.4 to 1.4 cases per 100,000 population per year during 2007–2017. During the study period, seventy-nine patients (65%) occurred among children younger than four years of age. Eight deaths occurred (7%), most of them among children under the age of 1 year (5 deaths; 15%). A serogroup was identified in 82 isolates. Most of the isolates (69 cases − 84%) belonged to serogroup B (NmB). IMD clustered geographically in the city of Bnei Brak, with a predominantly Ultra-Orthodox Jewish population. It is the youngest and most densely populated city in the district. The overall incidence rates of IMD among children in Bnei Brak were more than seven times higher in children up to nine years, compared to the rest of the district. Specifically for NmB, disease rates were 9.08 times higher in children up to the age of four, and 7.74 times higher in children from five to nine years old in Bnei Brak, compared to the rest of the district. Our findings describe the burden of a vaccine-preventable disease and reinforce the need for routine 4CmenB introduction, especially in groups where the disease clusters.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d79ce5799565b058ffa1135b50fa6c94Test
https://doi.org/10.1016/j.vaccine.2019.08.055Test

المؤلفون: G. Vidal, J. A. Gómez, M. Seoane, N. D. Giglio, P. Wetzler Malbrán

المصدر: Epidemiology and Infection

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Adolescent, Databases, Factual, Epidemiology, 030231 tropical medicine, Argentina, Meningitis, Meningococcal, Neisseria meningitidis, medicine.disease_cause, surveillance system, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Age Distribution, Environmental health, Medicine, Humans, Public Health Surveillance, 030212 general & internal medicine, Child, Disease burden, Aged, Retrospective Studies, underreporting, Estimation, Aged, 80 and over, Original Paper, business.industry, Incidence (epidemiology), Public health, Incidence, invasive meningococcal disease, Infant, Newborn, Infant, Retrospective cohort study, Middle Aged, Survival Analysis, Infectious Diseases, Invasive meningococcal disease, Child, Preschool, Bacterial meningitis, Female, business, bacterial meningitis

الوصف: Among the different existing types of bacterial meningitis, the one caused by Neisseria meningitidis is the main presentation of invasive meningococcal disease (IMD). IMD is a significant public health concern and has a reported incidence rate in Argentina of 0.44 cases per 100 000 inhabitants in 2015. However, the actual incidence is thought to be higher as passive surveillance systems neither report nor identify 100% of all cases. The aim of this study is to develop an estimation of the burden of IMD in Argentina closer to reality by adjusting/correcting several limitations observed in the surveillance data available. A retrospective observational study has been performed using four Argentinean national databases recording the number of IMD cases and deaths, serogroups of N. meningitidis and ages, between 2007 to 2016. The reported data were adjusted to account for underreporting and to also integrate the cases missed due to well-known limitations associated with the diagnosis of N. meningitidis detection methods. Data were further analysed by serogroups of N. meningitidis and by age groups. After these adjustments, the potential numbers of IMD cases and IMD-related deaths are estimated to be 3.1 and 1.9 higher than reported, respectively. The study corrects the previous underestimation of the disease burden and provides expectedly more robust estimates aligned with international evidence and highlights the importance of active surveillance, with high-quality methods, for a better definition of preventive strategies against IMD in Argentina.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6af22df2fa347288bfd25a5fed492c8Test
https://pubmed.ncbi.nlm.nih.gov/31779718Test

المؤلفون: Rock Aristide Sossou, Chinelo Ebruke, Joseph Agossou, Gérard Kpanidja, Moutawakilou Gomina, Peter Sylvanus Ndow, Abdoullah Condé, Falilatou Agbeille Mohamed, Jean Nounagnon, Catherine Okoi, François Hounsou, Eric Y Dènon, Brenda Kwambana-Adams, Martin Antonio, Alphonse Noudamadjo, Moussa Alassane, Archibald Worwui, Julien Didier Adédémy, Basile G Aouanou, Honoré S Bankolé, Jason M. Mwenda, Claire Oluwalana, Rolande Assogba, Mariam A Dogo

المصدر: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America

مصطلحات موضوعية: Microbiology (medical), Male, medicine.medical_specialty, Microbiological culture, Supplement Articles, Neisseria meningitidis, medicine.disease_cause, Pneumococcal conjugate vaccine, Haemophilus influenzae, Meningitis, Bacterial, Pneumococcal Vaccines, Internal medicine, Case fatality rate, Epidemiology, Streptococcus pneumoniae, Medicine, Benin, Humans, Serotyping, Vaccines, Conjugate, business.industry, Infant, Newborn, Infant, vaccines, medicine.disease, Infectious Diseases, pediatric, Child, Preschool, Female, business, bacterial meningitis, Meningitis, Sentinel Surveillance, pneumococcus, medicine.drug

الوصف: Background Pediatric bacterial meningitis (PBM) remains an important cause of disease in children in Africa. We describe findings from sentinel site bacterial meningitis surveillance in children
We conducted sentinel pediatric bacterial meningitis surveillance following pneumococcal conjugate vaccine introduction in Benin during 2011–2016. A total of 194 cases were confirmed, predominantly caused by pneumococcus (50.5%). Overall, meningitis and pneumococcal meningitis cases progressively declined during surveillance.

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b02f97fec14ea95e3149882ab672784Test

المؤلفون: Robert W. Baird, Jane E. Francis, Stephanie White, Hala Katf

المصدر: Journal of Paediatrics and Child Health. 54:1206-1212

مصطلحات موضوعية: Pediatrics, medicine.medical_specialty, business.industry, Incidence (epidemiology), Medical record, Neisseria meningitidis, 030231 tropical medicine, medicine.disease_cause, Indigenous, 03 medical and health sciences, 0302 clinical medicine, Pediatrics, Perinatology and Child Health, Streptococcus pneumoniae, Case fatality rate, Epidemiology, medicine, Bacterial meningitis, 030212 general & internal medicine, business

الوصف: AIM The epidemiology of community-acquired bacterial meningitis has changed following the introduction of routine immunisation against common causative organisms. Indigenous children living in the Northern Territory, Australia, have high rates of bacterial infections. This study describes changes in the epidemiology of childhood bacterial meningitis and the distribution of the burden of disease in the Top End. METHODS A retrospective review of cases derived from hospital medical records and laboratory data was performed. Inclusion criteria were children aged 3 months to 14 years of age, admitted to Royal Darwin Hospital between 1992 and 2014 and diagnosed with bacterial meningitis. Annual incidence of bacterial meningitis and the distribution of causative pathogens are described. Demographic data, investigations, treatment and outcomes were compared between Indigenous and non-Indigenous children. RESULTS There were 137 cases of childhood bacterial meningitis identified over the 23-year period. The incidence reduced from 21 per 100 000 children per year for 1992-2002 to 11 per 100 000 per year for 2003-2014 (P = 0.0025). Haemophilus influenzae type b, Streptococcus pneumoniae and Neisseria meningitidis were the most common causative organisms, with a reduction in cases for each pathogen observed across the study period. Indigenous children were over-represented (104/137, 76%). Case fatality rate was 8% (11/137); 91% of fatal cases presented to a remote facility. CONCLUSIONS The incidence of childhood bacterial meningitis has declined in the Northern Territory of Australia, but Indigenous children are disproportionately affected. Routine immunisation is beneficial for all, although further efforts to 'Close the Gap' between health outcomes in Indigenous and non-Indigenous Australians is required.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::64b91b4fe8bb961f0b6335f7b287c506Test
https://doi.org/10.1111/jpc.13936Test

المؤلفون: Bakhtygali Yerezhepov, James J. Sejvar, Nursulu Berdiyarova, Pawan Angra, Kaldikul Kulzhanova, Jennifer R. Head, Daniel E. Singer, Daphne B. Moffett, Yekaterina Bumburidi, Toni Whistler, Gulmira Utepbergenova

المصدر: PLoS ONE, Vol 16, Iss 5, p e0251494 (2021)
PLoS ONE

مصطلحات موضوعية: Bacterial Diseases, Male, Microbiological culture, Etiology, Physiology, Epidemiology, Neisseria meningitidis, Pathology and Laboratory Medicine, medicine.disease_cause, Nervous System, Geographical Locations, Medical Conditions, Infectious Diseases of the Nervous System, Medicine and Health Sciences, Simplexvirus, Child, Cerebrospinal Fluid, Enterovirus, Multidisciplinary, Incidence, Hospital based, Middle Aged, Meningitis, Viral, Kazakhstan, Hospitals, Bacterial Pathogens, Body Fluids, Europe, Infectious Diseases, Neurology, Medical Microbiology, Child, Preschool, Encephalitis, Medicine, Female, Pathogens, Anatomy, Neisseria, Meningitis, Research Article, Adult, medicine.medical_specialty, Asia, Adolescent, Inflammatory Diseases, Science, Microbiology, Meningitis, Bacterial, Young Adult, Bacterial Meningitis, Internal medicine, medicine, Humans, Microbial Pathogens, Aged, Bacteria, business.industry, Organisms, Biology and Life Sciences, Infant, medicine.disease, Herpes simplex virus, People and Places, business

الوصف: Encephalitis and meningitis (EM) are severe infections of the central nervous system associated with high morbidity and mortality. The etiology of EM in Kazakhstan is not clearly defined, so from February 1, 2017 to January 31, 2018 we conducted hospital-based syndromic surveillance for EM at the Shymkent City Hospital, in the South Kazakhstan region. All consenting inpatients meeting a standard case definition were enrolled. Blood and cerebrospinal fluid (CSF) samples were collected for bacterial culture, and CSF samples were additionally tested by PCR for four bacterial species and three viruses using a cascading algorithm. We enrolled 556 patients. Of these, 494 were of viral etiology (including 4 probable rabies cases), 37 were of bacterial etiology, 19 were of unknown etiology and 6 were not tested. The most commonly identified pathogens included enterovirus (73%, n = 406 cases), herpes simplex virus (12.8%, n = 71), andNeisseria meningitidis(3.8%, n = 21). The incidence rates (IRs) for enteroviral and meningococcal EM were found to be 14.5 and 0.7 per 100,000 persons, respectively. The IR for bacterial EM using both PCR and culture results was 3–5 times higher compared to culture-only results. Antibacterial medicines were used to treat 97.2% (480/494) of virus-associated EM. Incorporation of PCR into routine laboratory diagnostics of EM improves diagnosis, pathogen identification, ensures IRs are not underestimated, and can help avoid unnecessary antibacterial treatment.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ad29504161ab570ab4e62ff15683566Test
https://doi.org/10.1371/journal.pone.0251494Test

المؤلفون: Sani Ousmane, Jean Testa, Dan Dano Ibrahim, Lawaly Maman Manzo, Maman Zaneidou, Halima Boubacar Maïnassara

المساهمون: Centre de Recherche Médicale et Sanitaire (Niamey, Niger) (CERMES), Réseau International des Instituts Pasteur (RIIP), Direction de la Surveillance et de la Riposte aux Epidémies, Ministère de la Santé Publique [Niger], Risques, Epidémiologie, Territoire, INformations, Education et Santé (RETINES), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)

المصدر: The Pan African Medical Journal
The Pan African Medical Journal, Pan African Medical Center for Public Health Research and Information, 2018, 30, ⟨10.11604/pamj.2018.30.235.15937⟩
Pan African Medical Journal; Vol. 30 No. 1 (2018)

مصطلحات موضوعية: medicine.medical_specialty, Surveillance data, Adolescent, 030231 tropical medicine, Meningitis, Meningococcal, Neisseria meningitidis, Meningitis, Bacterial, 03 medical and health sciences, 0302 clinical medicine, Age groups, Internal medicine, Epidemiology, medicine, Serogroup c, Prevalence, Humans, 030212 general & internal medicine, Niger, Child, Meningitis, Haemophilus, ComputingMilieux_MISCELLANEOUS, business.industry, Meningitis, Pneumococcal, Research, Incidence, General Medicine, medicine.disease, Haemophilus influenzae, 3. Good health, Streptococcus pneumoniae, Infectious disease (medical specialty), Child, Preschool, Population Surveillance, Etiology, surveillance, Bacterial meningitis, epidemiology, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, business, bacterial meningitis, Meningitis

الوصف: Introduction: Bacterial meningitis (BM) is one of the most severe infectious disease in Niger republic. To best describe the trends of BM disease, meningitis surveillance data from the Centre de Recherche Medicale et Sanitaire (CERMES) and the Direction of Surveillance and Response to Epidemics (DSRE) were reviewed and analyzed. Methods: Data on number of notified cases of BM and on pathogens were analyzed during 2003-2015. Excel 2013 was used for trend analysis on the etiology of BM prevalence and incidence. Results: A total of 10051 cerebrospinal fluid (CSF) samples collected were confirmed by laboratory methods. The main etiologies of meningitis detected were N. meningitidis (82.1%), S. pneumonia (12.1%) and H. influenza (3.4%). N. meningitidis mostly affected children in the age groups of 5-9 years (32.9%) and 10-14 years (24.9%) with respective mean incidence of 14.9 and 11.3. The percentage estimate of N. meningitidis serogroup A (NmA) meningitis fell to 0% in 2015 while during the same year that of N. meningitidis serogroup C (NmC) and N. meningitidis serogroup W (NmW) reached 82.9% and 17% respectively. Conclusion: Overall, the epidemiological trends of the BM in Niger were dynamic. The emergence of NmC strains suggests that there may be an urgent need for serogroup C containing vaccines in Niger in the coming years. Keywords : Niger, epidemiology, bacterial meningitis, surveillance

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98b35746113036e4ba9982e64374cf76Test
https://hal.archives-ouvertes.fr/hal-02882011Test

المؤلفون: Robert Whittaker, Joana Gomes Dias, Miriam Ramliden, Csaba Ködmön, Assimoula Economopoulou, Netta Beer, Lucia Pastore Celentano, Elisabeth Kanitz, Lukas Richter, Wesley Mattheus, Corinne Bleyenheuft, Teodora Georgieva, Ivan Simeonovski, Vesna Višekruna Vučina, Sanja Kurečić Filipović, Maria Koliou, Despo Pieridou Bagatzouni, Pavla Krizova, Helena Sebestova, Steen Hoffmann, Palle Valentiner-Branth, Natalia Kerbo, Rita Peetso, Markku Kuusi, Maija Toropainen, Isabelle Parent, Muhamed-Kheir Taha, Ulrich Vogel, Wiebke Hellenbrand, Theano Georgakopoulou, Georgina Tzanakaki, Katalin Krisztalovics, Tamás Tirczka, Thorolfur Gudnason, Hjordis Hardardottir, Piaras O'Lorcain, Desiree Bennett, Fortunato D'Ancona, Paola Stefanelli, Larissa Savrasova, Darja Vasilevska, Nerija Kuprevičienė, Rasa Liausedienė, Irène Demuth, Gérard Scheiden, Jackie Maistre Melillo, Paul Caruana, Arie van der Ende, Liesbeth Mollema, Dominique Caugant, Hans Blystad, Anna Skoczyńska, Lavinia Zota, Marina Pana, Marta Grgič Vitek, Metka Paragi, Rosa Cano, Raquel Abad, Tiia Lepp, Helen Campbell

المساهمون: AII - Infectious diseases, Medical Microbiology and Infection Prevention, European Centre for Disease Prevention and Control [Stockholm, Sweden] (ECDC), Tufts University [Medford], Hellenic Centre for Diseases Control and Prevention (HCDCP), Members of the ECDC network for invasive meningococcal disease: Elisabeth Kanitz, Lukas Richter (Austria), Wesley Mattheus, Corinne Bleyenheuft (Belgium), Teodora Georgieva, Ivan Simeonovski (Bulgaria), Vesna Višekruna Vučina, Sanja Kurečić Filipović (Croatia), Maria Koliou, Despo Pieridou Bagatzouni (Cyprus), Pavla Krizova, HelenaSebestova (Czech Republic), Steen Hoffmann, PalleValentiner-Branth (Denmark), Natalia Kerbo, Rita Peetso (Estonia), Markku Kuusi, Maija Toropainen (Finland), Isabelle Parent, Muhamed-Kheir Taha (France), Ulrich Vogel, Wiebke Hellenbrand (Germany), Theano Georgakopoulou, Georgina Tzanakaki (Greece), Katalin Krisztalovics, Tamás Tirczka (Hungary), Thorolfur Gudnason, Hjordis Hardardottir (Iceland), Piaras O'Lorcain, Desiree Bennett (Ireland), Fortunato D'Ancona, Paola Stefanelli (Italy), Larissa Savrasova, Darja Vasilevska (Latvia), Nerija Kuprevičienė, Rasa Liausedienė (Lithuania), Irène Demuth, Gérard Scheiden (Luxembourg), Jackie Maistre Melillo, Paul Caruana (Malta), Arievan der Ende, Liesbeth Mollema (Netherlands), Dominique Caugant, Hans Blystad (Norway), Anna Skoczyńska (Poland), Lavinia Zota, Marina Pana (Romania), Marta Grgič Vitek, Metka Paragi (Slovenia), Rosa Cano, Raquel Abad (Spain), Tiia Lepp (Sweden), Helen Campbell (UK)

المصدر: Vaccine, 35(16), 2034-2041. Elsevier BV
Vaccine
Vaccine, 2017, 35 (16), pp.2034-2041. ⟨10.1016/j.vaccine.2017.03.007⟩

مصطلحات موضوعية: 0301 basic medicine, Male, Pediatrics, Epidemiology, MESH: Meningococcal Vaccines/administration & dosage, First year of life, Neisseria meningitidis, medicine.disease_cause, 0302 clinical medicine, MESH: Aged, 80 and over, MESH: Child, Medicine, 030212 general & internal medicine, MESH: Incidence, Child, MESH: Aged, Aged, 80 and over, education.field_of_study, Surveillance, MESH: Middle Aged, Incidence, MESH: Sex Distribution, Invasive meningococcal disease (IMD), Middle Aged, MESH: Infant, MESH: Sepsis/epidemiology, Vaccination, Europe, Infectious Diseases, Invasive meningococcal disease, MESH: Young Adult, Child, Preschool, Molecular Medicine, Bacterial meningitis, Female, Adult, medicine.medical_specialty, Adolescent, 030106 microbiology, Population, Meningococcal Vaccines, MESH: Meningitis, Meningococcal/epidemiology, Meningitis, Meningococcal, Serogroup, 03 medical and health sciences, Young Adult, Age Distribution, Environmental health, MESH: Meningitis, Meningococcal/prevention & control, Sepsis, Humans, Sex Distribution, education, MESH: Age Distribution, Aged, MESH: Adolescent, MESH: Humans, General Veterinary, General Immunology and Microbiology, business.industry, MESH: Child, Preschool, Public Health, Environmental and Occupational Health, Infant, MESH: Adult, MESH: Serogroup, MESH: Male, MESH: Europe/epidemiology, MESH: Neisseria meningitidis/isolation & purification, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, MESH: Neisseria meningitidis/classification, business, Notification rate, MESH: Female

الوصف: International audience; Background: Invasive meningococcal disease (IMD) is a major cause of bacterial meningitis and septi-caemia although infection by some serogroups may be prevented through vaccination. We aimed to describe the epidemiology of IMD in EU/EEA countries during 2004-2014 to monitor serogroup-and age-specific trends, and compare country trends by the period of meningococcal C conjugate (MCC) vaccine introduction.Methods: We analysed IMD surveillance data by age, gender, serogroup, country and outcome. We estimated the percentage change in annual notification rate (NR), using linear regression analysis of the log of the annual NR. We grouped countries by the year they introduced MCC vaccination into their routine immunisation programmes. Results: The overall NR was 0.9/100 000 population, and decreased 6.6% (95%CI: À8.0%;À5.1%) annually. Infants had the highest NR (16.0/100 000), and there were decreasing trends in all age groups

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d5f2219f91a5809a82efce43ed555cTest
https://doi.org/10.1016/j.vaccine.2017.03.007Test