المؤلفون: Bakhoum, Samuel F, Ngo, Bryan, Laughney, Ashley M, Cavallo, Julie-Ann, Murphy, Charles J, Ly, Peter, Shah, Pragya, Sriram, Roshan K, Watkins, Thomas BK, Taunk, Neil K, Duran, Mercedes, Pauli, Chantal, Shaw, Christine, Chadalavada, Kalyani, Rajasekhar, Vinagolu K, Genovese, Giulio, Venkatesan, Subramanian, Birkbak, Nicolai J, McGranahan, Nicholas, Lundquist, Mark, LaPlant, Quincey, Healey, John H, Elemento, Olivier, Chung, Christine H, Lee, Nancy Y, Imielenski, Marcin, Nanjangud, Gouri, Pe’er, Dana, Cleveland, Don W, Powell, Simon N, Lammerding, Jan, Swanton, Charles, Cantley, Lewis C

المصدر: Nature. 553(7689)

مصطلحات موضوعية: Genetics, HIV/AIDS, Aetiology, 2.1 Biological and endogenous factors, Cancer, Animals, Brain Neoplasms, Breast Neoplasms, Carcinoma, Squamous Cell, Cell Line, Chromosomal Instability, Chromosome Segregation, Cytosol, DNA, Neoplasm, Female, Head and Neck Neoplasms, Humans, Inflammation, Membrane Proteins, Mesoderm, Mice, Micronuclei, Chromosome-Defective, NF-kappa B, Neoplasm Metastasis, Nucleotidyltransferases, Xenograft Model Antitumor Assays, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/27h418ppTest

المؤلفون: Hu, Hai, Juvekar, Ashish, Lyssiotis, Costas A, Lien, Evan C, Albeck, John G, Oh, Doogie, Varma, Gopal, Hung, Yin Pun, Ullas, Soumya, Lauring, Josh, Seth, Pankaj, Lundquist, Mark R, Tolan, Dean R, Grant, Aaron K, Needleman, Daniel J, Asara, John M, Cantley, Lewis C, Wulf, Gerburg M

المصدر: Cell. 164(3)

مصطلحات موضوعية: Underpinning research, 1.1 Normal biological development and functioning, Animals, Breast Neoplasms, Cell Line, Tumor, Cytoskeleton, Cytosol, Disease Models, Animal, Epithelial Cells, Fructose-Bisphosphate Aldolase, Glycolysis, Humans, Insulin, Mice, Phosphatidylinositol 3-Kinases, Phosphoinositide-3 Kinase Inhibitors, Signal Transduction, Biological Sciences, Medical and Health Sciences, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/7hv4z168Test

المؤلفون: Weiner, Orion D, Rentel, Maike C, Ott, Alex, Brown, Glenn E, Jedrychowski, Mark, Yaffe, Michael B, Gygi, Steven P, Cantley, Lewis C, Bourne, Henry R, Kirschner, Marc W

المصدر: PLOS Biology. 4(2)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, 1.1 Normal biological development and functioning, Underpinning research, Generic health relevance, Actins, Animals, Cell Line, Cell Polarity, Chemotaxis, Enzyme Activation, Humans, Membrane Proteins, Molecular Sequence Data, Myosins, Neutrophils, Phosphatidylinositol Phosphates, Phosphorylation, Protein Binding, Protein Subunits, Reactive Oxygen Species, Terminology as Topic, Wiskott-Aldrich Syndrome Protein Family, rac GTP-Binding Proteins, Agricultural and Veterinary Sciences, Medical and Health Sciences, Developmental Biology, Agricultural, veterinary and food sciences, Biological sciences, Biomedical and clinical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/1sf3s72vTest

المؤلفون: Mayer, Ingrid A., Abramson, Vandana G., Formisano, Luigi, Balko, Justin M., Estrada, Mónica V., Sanders, Melinda E., Juric, Dejan, Solit, David, Berger, Michael F., Won, Helen H., Li, Yisheng, Cantley, Lewis C., Winer, Eric, Arteaga, Carlos L.

المساهمون: Mayer, Ingrid A., Abramson, Vandana G., Formisano, Luigi, Balko, Justin M., Estrada, Mónica V., Sanders, Melinda E., Juric, Dejan, Solit, David, Berger, Michael F., Won, Helen H., Li, Yisheng, Cantley, Lewis C., Winer, Eric, Arteaga, Carlos L.

مصطلحات موضوعية: Adult, Aged, Antineoplastic Combined Chemotherapy Protocol, Aromatase Inhibitor, Biomarkers, Tumor, Breast Neoplasm, Cell Line, DNA Mutational Analysi, Female, Human, In Situ Hybridization, Fluorescence, Maximum Tolerated Dose, Middle Aged, Mutation, Neoplasm Metastasi, Neoplasm Staging, Nitrile, Phosphatidylinositol 3-Kinase, Receptor, ErbB-2, Fibroblast Growth Factor, Type 1, Receptors, Estrogen, Thiazole, Treatment Outcome, Triazole, Oncology

العلاقة: info:eu-repo/semantics/altIdentifier/wos/WOS:000393876300006; volume:23; issue:1; firstpage:26; lastpage:34; numberofpages:9; journal:CLINICAL CANCER RESEARCH; http://hdl.handle.net/11588/698508Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85010301206; http://clincancerres.aacrjournals.org/content/23/1/26.full-text.pdfTest

الإتاحة: https://doi.org/10.1158/1078-0432.CCR-16-0134Test
http://hdl.handle.net/11588/698508Test
http://clincancerres.aacrjournals.org/content/23/1/26.full-text.pdfTest

المؤلفون: González-Billalabeitia, Enrique, Seitzer, Nina, Song, Su Jung, Song, Min Sup, Patnaik, Akash, Liu, Xue-Song, Epping, Mirjam T, Papa, Antonella, Hobbs, Robin M, Chen, Ming, Lunardi, Andrea, Ng, Christopher, Webster, Kaitlyn A, Signoretti, Sabina, Loda, Massimo, Asara, John M, Nardella, Caterina, Clohessy, John G, Cantley, Lewis C, Pandolfi, Pier Paolo

مصطلحات موضوعية: Cell Line, Tumor, Animals, Humans, Mice, Prostatic Neoplasms, Poly(ADP-ribose) Polymerases, Cell Aging, Apoptosis, Male, Tumor Suppressor Protein p53, PTEN Phosphohydrolase, Elafin, Molecular Targeted Therapy, Poly(ADP-ribose) Polymerase Inhibitors

وصف الملف: application/pdf

العلاقة: Cancer discovery; 2159-8290.CD-13-0230; https://hdl.handle.net/10161/20383Test

الإتاحة: https://hdl.handle.net/10161/20383Test

المؤلفون: Shaw, Reuben J, Kosmatka, Monica, Bardeesy, Nabeel, Hurley, Rebecca L, Witters, Lee A, DePinho, Ronald A, Cantley, Lewis C

المصدر: Dartmouth Scholarship

مصطلحات موضوعية: amp-activated protein kinases, adaptor proteins, signal transducing, amino acid sequence, animals, apoptosis, physiology, carrier proteins, cell line, energy metabolism, enzyme activation, hela cells, humans, in vitro techniques, llc-pk1 cells, mice, knockout, models, biological, multienzyme complexes, chemistry, genetics, metabolism, phosphorylation, protein kinases, protein-serine-threonine kinases, proteins, recombinant proteins, swine, threonine

وصف الملف: application/pdf

العلاقة: https://digitalcommons.dartmouth.edu/facoa/1584Test; https://digitalcommons.dartmouth.edu/context/facoa/article/2587/viewcontent/ptpmcrender.fcgiTest

الإتاحة: https://doi.org/10.1073/pnas.0308061100Test
https://digitalcommons.dartmouth.edu/facoa/1584Test
https://digitalcommons.dartmouth.edu/context/facoa/article/2587/viewcontent/ptpmcrender.fcgiTest

المؤلفون: González Billalabeitia, Enrique, Seitzer, Nina, Song, Su Jung, Song, Min Sup, Patnaik, Akash, Liu, Xue Song, Epping, Mirjam T., Papa, Antonella, Hobbs, Robin M., Chen, Ming, Ng, Christopher, Webster, Kaitlyn A., Signoretti, Sabina, Loda, Massimo, Asara, John M., Nardella, Caterina, Clohessy, John G., Cantley, Lewis C., Pandolfi, Pier Paolo, Lunardi, Andrea

المساهمون: González Billalabeitia, Enrique, Seitzer, Nina, Song, Su Jung, Song, Min Sup, Patnaik, Akash, Liu, Xue Song, Epping, Mirjam T., Papa, Antonella, Hobbs, Robin M., Chen, Ming, Lunardi, Andrea, Ng, Christopher, Webster, Kaitlyn A., Signoretti, Sabina, Loda, Massimo, Asara, John M., Nardella, Caterina, Clohessy, John G., Cantley, Lewis C., Pandolfi, Pier Paolo

مصطلحات موضوعية: Animal, Apoptosi, Cell Aging, Cell Line, Tumor, Elafin, Human, Male, Mice, Molecular Targeted Therapy, PTEN Phosphohydrolase, Poly(ADP-ribose) Polymerase Inhibitor, Poly(ADP-ribose) Polymerase, Prostatic Neoplasm, Tumor Suppressor Protein p53, Oncology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/24866151; info:eu-repo/semantics/altIdentifier/wos/WOS:000343120400024; volume:4; issue:8; firstpage:896; lastpage:904; numberofpages:9; journal:CANCER DISCOVERY; http://hdl.handle.net/11572/128165Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84905493584; http://cancerdiscovery.aacrjournals.org/content/4/8/896.full.pdfTest

الإتاحة: https://doi.org/10.1158/2159-8290.CD-13-0230Test
http://hdl.handle.net/11572/128165Test
http://cancerdiscovery.aacrjournals.org/content/4/8/896.full.pdfTest

المؤلفون: Lunardi, Andrea, Ala, Ugo, Epping, Mirjam T., Salmena, Leonardo, Clohessy, John G., Webster, Kaitlyn A., Wang, Guocan, Mazzucchelli, Roberta, Bianconi, Maristella, Stack, Edward C., Lis, Rosina, Patnaik, Akash, Cantley, Lewis C., Bubley, Glenn, Cordon Cardo, Carlos, Gerald, William L., Montironi, Rodolfo, Signoretti, Sabina, Loda, Massimo, Nardella, Caterina, Pandolfi, Pier Paolo

المساهمون: Lunardi, Andrea, Ala, Ugo, Epping, Mirjam T., Salmena, Leonardo, Clohessy, John G., Webster, Kaitlyn A., Wang, Guocan, Mazzucchelli, Roberta, Bianconi, Maristella, Stack, Edward C., Lis, Rosina, Patnaik, Akash, Cantley, Lewis C., Bubley, Glenn, Cordon Cardo, Carlo, Gerald, William L., Montironi, Rodolfo, Signoretti, Sabina, Loda, Massimo, Nardella, Caterina, Pandolfi, Pier Paolo

مصطلحات موضوعية: Androgen Antagonist, Androgen, Animal, Antineoplastic Agent, Cell Line, Tumor, Drug Evaluation, Preclinical, Human, Male, Mice, Transgenic, Models, Biological, Orchiectomy, PTEN Phosphohydrolase, Phenylthiohydantoin, Prostatic Neoplasm, Signal Transduction, Translational Medical Research, Treatment Failure, Therapies, Investigational, Genetics

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/23727860; info:eu-repo/semantics/altIdentifier/wos/WOS:000321005200009; volume:45; issue:7; firstpage:747; lastpage:755; numberofpages:9; journal:NATURE GENETICS; http://hdl.handle.net/11572/128180Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84879671701

الإتاحة: https://doi.org/10.1038/ng.2650Test
http://hdl.handle.net/11572/128180Test

المؤلفون: Baker, Rachael, Lewis, Steven M, Sasaki, Atsuo T, Wilkerson, Emily M, Locasale, Jason W, Cantley, Lewis C, Kuhlman, Brian, Dohlman, Henrik G, Campbell, Sharon L

المصدر: Nature Structural and Molecular Biology, 20(1)

مصطلحات موضوعية: Ubiquitination, Guanine, ras GTPase-Activating Proteins, Humans, Cell Differentiation, Cell Line, HEK293 Cells, Cell Proliferation, Signal Transduction, ras Proteins

العلاقة: https://doi.org/10.17615/1ca2-0y14Test; https://cdr.lib.unc.edu/downloads/fq978234d?file=thumbnailTest; https://cdr.lib.unc.edu/downloads/fq978234dTest

الإتاحة: https://doi.org/10.17615/1ca2-0y14Test
https://cdr.lib.unc.edu/downloads/fq978234d?file=thumbnailTest
https://cdr.lib.unc.edu/downloads/fq978234dTest

المؤلفون: Liu, Yan, Marks, Kevin, Cowley, Glenn S., Carretero, Julian, Liu, Qingsong, Niel, Thomas J.F., Xu, Chunxiao, Cohoon, Travis J., Gao, Peng, Zhang, Yong, Chen, Zhao, Altabef, Abigail B., Tchaicha, Jeremy H., Wang, Xiaoxu, Choe, Sung, Driggers, Edward M., Zhang, Jianming, Bailey, Sean T., Sharpless, Norman E., Neil Hayes, D., Patel, Nirali M., Janne, Pasi A., Bardeesy, Nabeel, Engelman, Jeffrey A., Manning, Brendan D., Shaw, Reuben J., Asara, John M., Scully, Ralph, Kimmelman, Alec, Byers, Lauren A., Gibbons, Don L., Wistuba, Ignacio I., Heymach, John V., Kwiatkowski, David J., Kim, William Y., Kung, Andrew L., Gray, Nathanael S., Root, David E., Cantley, Lewis C., Wong, Kwok Kin

المصدر: Cancer Discovery, 3(8)

مصطلحات موضوعية: Animals, Lung Neoplasms, Carcinoma, Non-Small-Cell Lung, High-Throughput Screening Assays, Molecular Targeted Therapy, Genomics, Nucleoside-Phosphate Kinase, Gene Knockdown Techniques, Humans, Cell Death, Mice, DNA Replication, Models, Genetic, DNA Damage, Metabolomics, Cell Line, Tumor

العلاقة: https://doi.org/10.17615/ge7q-0q17Test; https://cdr.lib.unc.edu/downloads/tm70n223s?file=thumbnailTest; https://cdr.lib.unc.edu/downloads/tm70n223sTest

الإتاحة: https://doi.org/10.17615/ge7q-0q17Test
https://cdr.lib.unc.edu/downloads/tm70n223s?file=thumbnailTest
https://cdr.lib.unc.edu/downloads/tm70n223sTest