المؤلفون: Scott Q. Harper, Nicolas Wein, Gholamhossein Amini-Chermahini, Noah K. Taylor, Afrooz Rashnonejad

المصدر: Molecular Therapy: Nucleic Acids, Vol 23, Iss, Pp 476-486 (2021)

مصطلحات موضوعية: 0301 basic medicine, DUX4, Genetic enhancement, Biology, Vectors in gene therapy, U7, 03 medical and health sciences, 0302 clinical medicine, snRNA, RNA interference, Drug Discovery, medicine, Gene silencing, Facioscapulohumeral muscular dystrophy, FSHD, Myogenesis, lcsh:RM1-950, medicine.disease, gene therapy, Cell biology, RNA silencing, lcsh:Therapeutics. Pharmacology, 030104 developmental biology, 030220 oncology & carcinogenesis, Molecular Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02b7486e41f503ad62b48e163701f988Test
https://doi.org/10.1016/j.omtn.2020.12.004Test

المؤلفون: Charis L. Himeda, Takako I. Jones, Peter L. Jones

المصدر: Molecular Therapy: Methods & Clinical Development, Vol 20, Iss, Pp 298-311 (2021)
Molecular Therapy. Methods & Clinical Development

مصطلحات موضوعية: 0301 basic medicine, muscular dystrophy, lcsh:QH426-470, DUX4, facioscapulohumeral muscular dystrophy, Biology, dCas9, 03 medical and health sciences, 0302 clinical medicine, CRISPR inhibition, Genetics, medicine, Facioscapulohumeral muscular dystrophy, Gene silencing, CRISPR, lcsh:QH573-671, Molecular Biology, Psychological repression, Regulation of gene expression, FSHD, Cas9, lcsh:Cytology, AAV, medicine.disease, gene therapy, Cell biology, Chromatin, lcsh:Genetics, 030104 developmental biology, 030220 oncology & carcinogenesis, Epigenetic Repression, Molecular Medicine, Original Article, gene regulation, epigenetic repression

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::509d33943db1210b156f4baf85f0fd2bTest
http://www.sciencedirect.com/science/article/pii/S2329050120302497Test

المؤلفون: Esin Guvenir Celik, Hilmi Uysal, Hacer Kaya, Sibel Berker Karauzum, Onur Eroglu, Ceren Hangul

المساهمون: Güvenir Çelik, Esin, Kaya, Hacer, Eroğlu, Onur

المصدر: Turkish Journal of Biochemistry. 46:435-444

مصطلحات موضوعية: 0301 basic medicine, Skeletal Muscle, DUX4, Facioscapulohumeral Muscular Dystrophy, Clinical Biochemistry, PAX3, Biology, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, medicine, Facioscapulohumeral muscular dystrophy, Myocyte, Molecular Biology, FSHD, Estradiol, Biochemistry (medical), β-catenin, musculoskeletal system, medicine.disease, PAX7, 030104 developmental biology, Catenin, Cancer research, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a11122fa0f6d9a40acff7acd1ad2d33Test
https://doi.org/10.1515/tjb-2020-0351Test

المؤلفون: Ator Rafael Odisho Ashoti

المساهمون: Laat, W.L. de, Geijsen, N., University Utrecht

مصطلحات موضوعية: musculoskeletal diseases, FSHD, congenital, hereditary, and neonatal diseases and abnormalities, Mitigation methods, DUX4, Computational biology, Biology, DUX4-induced cytotoxicity, Cascade, DUX4, FSHD, early targets, DUX4-induced cytotoxicity, modulators, CRISPR/Cas9, Cytotoxic T cell, CRISPR, modulators, early targets, CRISPR/Cas9

وصف الملف: image/pdf; text/plain

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83926c32c3d2fc98f0181bf3483a9b0aTest
https://dspace.library.uu.nl/handle/1874/402543Test

المؤلفون: Moyle, LA, Blanc, E, Jaka, O, Prueller, J, Banerji, CRS, Tedesco, FS, Harridge, SDR, Knight, RD, Zammit, PS

المصدر: ELIFE , 5 (e11405) (2016)

مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Biology, Life Sciences & Biomedicine - Other Topics, ENTERIC NERVOUS-SYSTEM, FSHD CANDIDATE GENE, FACTOR-RECEPTOR RET, NEUROTROPHIC FACTOR, SKELETAL-MUSCLE, SATELLITE CELLS, FAMILY-RECEPTOR, MYOGENIC DIFFERENTIATION, OXIDATIVE STRESS, MICE LACKING

وصف الملف: text

العلاقة: https://discovery.ucl.ac.uk/id/eprint/1529141/1/e11405-download.pdfTest; https://discovery.ucl.ac.uk/id/eprint/1529141Test/

الإتاحة: https://discovery.ucl.ac.uk/id/eprint/1529141/1/e11405-download.pdfTest
https://discovery.ucl.ac.uk/id/eprint/1529141Test/

المؤلفون: McCullers, Michelle Rene

المساهمون: Dr. Chadwick, Florida State University

المصدر: The Owl; Vol 6, No 1 (2016): The Best of The Owl

مصطلحات موضوعية: Biology, epigenetics, macrosatellite, FSHD, gene regulation

وصف الملف: application/pdf

العلاقة: http://journals.fcla.edu/owl/article/view/87222/84733Test; http://journals.fcla.edu/owl/article/view/87222Test

الإتاحة: http://journals.fcla.edu/owl/article/view/87222Test

المؤلفون: Fan Yang, Depeng Wang, Liying Cui, Yu Huang, Pidong Li, Shangzhi Huang, Zhi-Qiang Wang, Kai Wang, Jiapeng Zhou, Li Fang, Fan Liang, Yi Dai

المصدر: Journal of Medical Genetics

مصطلحات موضوعية: musculoskeletal diseases, Adult, Male, congenital, hereditary, and neonatal diseases and abnormalities, Adolescent, facioscapulohumeral muscular dystrophy, Computational biology, Biology, macrosatellite, Young Adult, Segmental Duplications, Genomic, Tandem repeat, Methods, Genetics, medicine, Humans, Facioscapulohumeral muscular dystrophy, Muscular dystrophy, Allele, Alleles, Genetics (clinical), Segmental duplication, Southern blot, FSHD, D4Z4, Haplotype, DNA, Middle Aged, Telomere, medicine.disease, Muscular Dystrophy, Facioscapulohumeral, Single Molecule Imaging, Pedigree, Restriction enzyme, Haplotypes, Tandem Repeat Sequences, single-molecule optical mapping, Female, Chromosomes, Human, Pair 4

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f0164ec2609c29ef569811b520343faTest
https://doi.org/10.1136/jmedgenet-2019-106078Test

المؤلفون: Takako I. Jones, Taylor Gould, Peter L. Jones

المصدر: Diagnostics, Vol 11, Iss 1469, p 1469 (2021)
Diagnostics
Volume 11
Issue 8

مصطلحات موضوعية: musculoskeletal diseases, muscular dystrophy, congenital, hereditary, and neonatal diseases and abnormalities, FSHD, Medicine (General), D4Z4, DNA methylation, epigenetics, DUX4, Clinical Biochemistry, Chromosome, Locus (genetics), Computational biology, Biology, Amplicon, medicine.disease, Article, nervous system diseases, Bisulfite, R5-920, medicine, Facioscapulohumeral muscular dystrophy, Epigenetics

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::918dda515aa31db7baf63683e902d71eTest
https://www.mdpi.com/2075-4418/11/8/1469Test

المؤلفون: Takako I. Jones, Andreia M Nunes, M. O. Ramírez, Peter L. Jones

المصدر: Disease Models & Mechanisms, Vol 14, Iss 8 (2021)
Disease Models & Mechanisms
article-version (VoR) Version of Record

مصطلحات موضوعية: musculoskeletal diseases, Genetically modified mouse, Neuromuscular Disease Models, congenital, hereditary, and neonatal diseases and abnormalities, Neuroscience (miscellaneous), Medicine (miscellaneous), Biology, Skeletal Myocytes, Bioinformatics, General Biochemistry, Genetics and Molecular Biology, fshd, Mice, Immunology and Microbiology (miscellaneous), DUX4, microRNA, dux4, Pathology, medicine, Animals, Humans, RB1-214, Facioscapulohumeral muscular dystrophy, Muscle, Skeletal, Homeodomain Proteins, Skeletal muscle, medicine.disease, Phenotype, Muscular Dystrophy, Facioscapulohumeral, nervous system diseases, MicroRNAs, medicine.anatomical_structure, biomarker, Medicine, Biomarker (medicine), mir-206, Biomarkers, Research Article, mirna

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc6f431a5b82fa0033d275635b0deaadTest
https://doi.org/10.1242/dmm.049016Test

المؤلفون: E. N. Popova, Anna Karpukhina, Ivan I. Galkin, Carla Dib, Olga Pletjushkina, Yinxing Ma, Roman A. Zinovkin, Boris V. Chernyak, Yegor S. Vassetzky

المساهمون: Aspects métaboliques et systémiques de l'oncogénèse pour de nouvelles approches thérapeutiques (METSY), Institut Gustave Roussy (IGR)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Koltzov Institute of Developmental Biology, the Russian Academy of Sciences [Moscow, Russia] (RAS), Lomonosov Moscow State University (MSU), Belozersky Institute of Physico-Chemical Biology

المصدر: Redox Biology, Vol 43, Iss, Pp 102008-(2021)
Redox Biology
Redox Biology, Elsevier, 2021, 43, pp.102008. ⟨10.1016/j.redox.2021.102008⟩

مصطلحات موضوعية: 0301 basic medicine, Mitochondrial ROS, Medicine (General), DUX4, QH301-705.5, Short Communication, Clinical Biochemistry, Biology, medicine.disease_cause, Biochemistry, Transcriptome, Myoblasts, 03 medical and health sciences, 0302 clinical medicine, R5-920, Downregulation and upregulation, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], medicine, Myocyte, Gene silencing, Humans, Biology (General), PITX1, Muscle differentiation, Homeodomain Proteins, FSHD, Organic Chemistry, Dystrophy, Cell Differentiation, Muscular Dystrophy, Facioscapulohumeral, 3. Good health, Cell biology, 030104 developmental biology, Oxidative stress, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0614c56056daeefe87ccc767ebdd5b62Test
http://www.sciencedirect.com/science/article/pii/S221323172100166XTest