المؤلفون: Helen Lenthall, Isabelle Meyts, Robert Brink, Kathryn Payne, Christoph Burkhart, Kaan Boztug, Wei Shi, Elise French, Melanie Wong, Lynn M. Corcoran, Gulbu Uzel, William A. Sewell, Michael O'Sullivan, Lucinda J. Berglund, Danielle T. Avery, Alisa Kane, David Zahra, Paul Gray, Danyal Butt, Tri Giang Phan, Anthony Lau, Sharon Choo, Stuart G. Tangye, Henry Brigden, Peter Hsu, Elissa K. Deenick, Jana R. Hermes, Theresa Cole, Tina Nguyen, Michael Elliott, Cindy S. Ma, Julia Bier, Steven M. Holland, Akira Nguyen

المصدر: The Journal of Experimental Medicine

مصطلحات موضوعية: 0301 basic medicine, Cellular differentiation, Antibody Affinity, PI3 KINASE, Research & Experimental Medicine, PHOSPHOINOSITIDE 3-KINASE, medicine.disease_cause, CLASS-SWITCH RECOMBINATION, Mice, Phosphatidylinositol 3-Kinases, HUMAN IMMUNODEFICIENCY, SECRETING CELLS, Immunology and Allergy, Child, Research Articles, B-Lymphocytes, Mutation, biology, Cell Differentiation, Cytidine deaminase, ANTIBODY-PRODUCTION, 3. Good health, Cell biology, Phenotype, medicine.anatomical_structure, ANTIGEN AFFINITY, Medicine, Research & Experimental, Gain of Function Mutation, Models, Animal, PHOSPHATIDYLINOSITOL 3-KINASE, Antibody, Life Sciences & Biomedicine, Signal Transduction, Class I Phosphatidylinositol 3-Kinases, Plasma Cells, Immunology, Immunoglobulins, Bone Marrow Cells, Article, 03 medical and health sciences, Germline mutation, Immune system, medicine, 3-KINASE DELTA SYNDROME, Animals, Humans, Germ-Line Mutation, B cell, Cell Proliferation, P85-ALPHA SUBUNIT, Science & Technology, Interleukins, biochemical phenomena, metabolism, and nutrition, Immunoglobulin Class Switching, 030104 developmental biology, Immunoglobulin class switching, biology.protein

وصف الملف: Print-Electronic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb0e6265bfc33cb2d8fc21980955e4a9Test
https://doi.org/10.1084/jem.20180010Test

المؤلفون: Fabienne Mackay, Danielle T. Avery, Kristy O'Donnell, Simona Infantino, Stuart G. Tangye, Vanessa L. Bryant, Gabrielle T. Belz, Michael Elliott, David M. Tarlinton, Amanda Light, Stéphane Richard

المصدر: Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)

مصطلحات موضوعية: 0301 basic medicine, Cell signaling, Protein-Arginine N-Methyltransferases, Arginine, Cellular differentiation, Science, B-cell receptor, General Physics and Astronomy, Biology, Lymphocyte Activation, Methylation, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, medicine, Animals, Humans, lcsh:Science, B cell, B-Lymphocytes, Multidisciplinary, Germinal center, Cell Differentiation, General Chemistry, 3. Good health, Cell biology, Immunity, Humoral, Repressor Proteins, 030104 developmental biology, medicine.anatomical_structure, Biochemistry, 030220 oncology & carcinogenesis, lcsh:Q, Signal transduction, Protein Processing, Post-Translational

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea770da252488a40c3e6392d28050717Test
http://europepmc.org/articles/PMC5638811Test

المؤلفون: Cindy S. Ma, Christoph Klein, Anna Chan, Stéphanie Boisson-Dupuis, Diana Averbuch, Megan L. Ives, Stephen Adelstein, Jean-Laurent Casanova, David A. Fulcher, Dan Engelhard, Peter D. Arkwright, Anne Durandy, Gulbu Uzel, Jane Peake, Masao Kobayashi, Matthew C. Cook, Sharon Choo, Stuart G. Tangye, Danielle T. Avery, Jennifer Stoddard, Martyn A. French, Steven M. Holland, Lucinda J. Berglund, Elissa K. Deenick, Jacinta Bustamante, Melanie Wong, Miyuki Tsumura, Capucine Picard, Joanne Smart, Joachim Roesler, Leen Moens

المصدر: The Journal of Experimental Medicine

مصطلحات موضوعية: STAT3 Transcription Factor, Cellular differentiation, Immunology, Naive B cell, Plasma Cells, Immunoglobulin G, Atacicept, Article, 03 medical and health sciences, 0302 clinical medicine, Antigen, medicine, STAT5 Transcription Factor, Immunology and Allergy, Humans, Cell Lineage, Memory B cell, 030304 developmental biology, 0303 health sciences, B-Lymphocytes, CD40, biology, Interleukins, Interleukin-21 Receptor alpha Subunit, Cell Differentiation, medicine.disease, 3. Good health, Cell biology, Interleukin-10, Tumor Necrosis Factor Receptor Superfamily, Member 7, B-1 cell, STAT1 Transcription Factor, Mutation, biology.protein, Immunologic Memory, 030215 immunology, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c7412c58cb8ae777d42a735e4972ddTest
http://europepmc.org/articles/PMC3832925Test

المؤلفون: Martyn A. French, Sharon Choo, Jean-Laurent Casanova, Klaus Magdorf, Stéphanie Boisson-Dupuis, Cindy S. Ma, Melanie Wong, Joanne Smart, Dan Engelhard, Alexandra Y. Kreins, Jane Peake, David A. Fulcher, Peter D. Arkwright, Anna Chan, Paul Gray, Sara Sebnem Kilic, Yoshiyuki Minegishi, Diana Averbuch, Elissa K. Deenick, Jacinta Bustamante, Marcel Batten, Matthew C. Cook, Stuart G. Tangye, Danielle T. Avery, Shigeaki Nonoyama

المساهمون: Uludağ Üniversitesi/Tıp Fakültesi/Pediatri Anabilim Dalı., Kılıç, Sara Şebnem, AAH-1658-2021

المصدر: Blood. 119:3997-4008

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Interleukin 12 receptor beta1, Cellular differentiation, Lymphocyte Activation, Biochemistry, CXCR5, Protein bcl 6, Tyrosine phosphorylation, Interleukin 12, In vivo study, Mice, Interleukin 21, Icos, Cytotoxic T cell, Helper Cell, Germinal Center, Interleukin-21, Cells, Cultured, Priority journal, B-Lymphocytes, Cxc chemokine receptor-5, Chemokine receptor cxcr5, Receptors, Interleukin-12, Cell Differentiation, T-Lymphocytes, Helper-Inducer, Hematology, BCL6, Protein kinase tyk2, Interleukin-12, Lymphocyte differentiation, STAT1 Transcription Factor, Differentiation, Helper cell, Cytokines, Mutations, Human, Signal Transduction, Adult, STAT3 Transcription Factor, Adolescent, Il-21, Bcl6, Immunology, Biology, Stat1 protein, Article, Antibody-responses, Immunocompromised Host, Animals, Humans, Mycobacterial, Th17 cells, Gene mutation, Immunobiology, Cell lineage, TYK2 Kinase, CD4+ T lymphocyte, B lymphocyte, Cell growth, In vitro study, Cell Biology, Human cell, Cell culture, Mutation, Cancer research, Protein expression, Cell maturation, Cell line, Stat3 protein, Controlled study, Transcription Factors

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49d91e41ee7cd7c3df59b9257d69ecadTest
https://doi.org/10.1182/blood-2011-11-392985Test

المؤلفون: Geetha Rao, Dianne E. Campbell, Anne Puel, Masao Kobayashi, Matthew C. Cook, Sara Sebnem Kilic, Danielle T. Avery, Rita Beier, Polina Stepensky, Stéphanie Boisson-Dupuis, Yoshiyuki Minegishi, Stuart G. Tangye, Davood Mansouri, Michael Stormon, Satoshi Okada, Shigeaki Nonoyama, Thomas Hambridge, Jean-Laurent Casanova, Stephen Adelstein, Joanne Smart, David A. Fulcher, Klaus Warnatz, Kaan Boztug, Kathryn Payne, Tony Roscioli, Annaliesse Blincoe, Steven M. Holland, Aydan Kansu, Gulbu Uzel, Jamila El Baghdadi, Bodo Grimbacher, Aziz Bousfiha, James Torpy, Seyed Alireza Mahdaviani, Capucine Picard, Simon J. Pelham, Aydan Ikinciogullari, Natalie Wong, Paul Gray, Martyn A. French, Tri Giang Phan, Melanie Wong, Cindy S. Ma, Ulrich Baumann, Peter Hsu, Elissa K. Deenick, Jacinta Bustamante, Peter D. Arkwright, John B. Ziegler, Jennifer Stoddard

المصدر: The Journal of allergy and clinical immunology. 136(4)

مصطلحات موضوعية: STAT3 Transcription Factor, Cellular differentiation, Immunology, Cell, CD40 Ligand, Medizin, medicine.disease_cause, Lymphocyte Activation, Article, Autoimmunity, Inducible T-Cell Co-Stimulator Protein, Interferon-gamma, Immune system, T-Lymphocyte Subsets, medicine, Agammaglobulinaemia Tyrosine Kinase, Immunology and Allergy, Bruton's tyrosine kinase, Humans, Receptors, Cytokine, Immunodeficiency, Cells, Cultured, Cell Proliferation, B-Lymphocytes, biology, Immunologic Deficiency Syndromes, Cell Differentiation, T-Lymphocytes, Helper-Inducer, Protein-Tyrosine Kinases, medicine.disease, Phenotype, I-kappa B Kinase, Immunity, Humoral, medicine.anatomical_structure, STAT1 Transcription Factor, Humoral immunity, Mutation, biology.protein, Immunologic Memory, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa0b2dd22d1418555169863e84a7aebcTest
https://pubmed.ncbi.nlm.nih.gov/26162572Test

المؤلفون: David A. Fulcher, Stephen Adelstein, Melanie Wong, Leen Moens, Rosa Bacchetta, Peter D. Arkwright, Harjit Dadi, Stéphanie Boisson-Dupuis, Anne Durandy, Liliana Bezrodnik, Capucine Picard, John B. Ziegler, Danielle T. Avery, Masao Kobayashi, Gulbu Uzel, Matthew C. Cook, Elissa K. Deenick, Lucinda J. Berglund, Jacinta Bustamante, Stuart G. Tangye, Joanne Smart, Chaim M. Roifman, Jean-Laurent Casanova, Cindy S. Ma

مصطلحات موضوعية: STAT3 Transcription Factor, medicine.medical_treatment, Immunology, B-cell receptor, Naive B cell, CD40 Ligand, Plasma Cells, Gene Expression, Biology, Plasma cell, Biochemistry, Cell Line, Interleukin 21, medicine, Humans, IL-2 receptor, Cells, Cultured, Immunobiology, Cell Proliferation, Oligonucleotide Array Sequence Analysis, B-Lymphocytes, CD40, Reverse Transcriptase Polymerase Chain Reaction, Interleukins, Interleukin-2 Receptor alpha Subunit, Cell Differentiation, Cell Biology, Hematology, Cell biology, Interleukin-10, Interleukin 10, Cytokine, medicine.anatomical_structure, Mutation, biology.protein, Interleukin-2, Transcriptome, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::425bd1bbb6acf7bb74ef5d27c96f1e38Test
https://europepmc.org/articles/PMC3854113Test/