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المؤلفون: Anna Makowska, Franciszek Sączewski, Patrick J. Bednarski, Maria Gdaniec, Łukasz Balewski, Magdalena Warmbier, Anita Kornicka
المصدر: Molecules; Volume 27; Issue 21; Pages: 7155
مصطلحات موضوعية: Benzoxazoles, Triazines, Organic Chemistry, Pharmaceutical Science, 2-iminocoumarins, 2-imino-2H-chromene, 2H-chromen-2-imines, 1,3,5-triazines, benzoxazoles, benzothiazoles, copper(II) complexes, X-ray analysis, in vitro cytotoxic activity, Antineoplastic Agents, Crystallography, X-Ray, Ligands, Analytical Chemistry, Chemistry (miscellaneous), Coordination Complexes, Cell Line, Tumor, Drug Discovery, Molecular Medicine, Humans, Benzothiazoles, Imines, Physical and Theoretical Chemistry, Copper
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3a5d5d2eaa82a3868668b1787929cadTest
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المؤلفون: Lisa Wolff, Siva Sankar Murthy Bandaru, Elias Eger, Hoai-Nhi Lam, Martin Napierkowski, Daniel Baecker, Carola Schulzke, Patrick J. Bednarski
المصدر: International Journal of Molecular Sciences
Volume 22
Issue 14
International Journal of Molecular Sciences, Vol 22, Iss 7631, p 7631 (2021)مصطلحات موضوعية: reactive oxygen species, pentathiepin, Molecular Structure, QH301-705.5, Antineoplastic Agents, Apoptosis, Glutathione, Article, Chemistry, Oxidative Stress, Structure-Activity Relationship, Glutathione Peroxidase GPX1, Cell Line, Tumor, sulfur, cancer cells, Humans, cytotoxicity, DNA damage, Biology (General), Thiepins, glutathione peroxidase, QD1-999, Cell Proliferation
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a7d2a658a7aaf555df3e4e6858275624Test
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المؤلفون: Solomon Tesfaye, Hannah Braun, Kaleab Asres, Ephrem Engidawork, Anteneh Belete, Ilias Muhammad, Christian Schulze, Nadin Schultze, Sebastian Guenther, Patrick J. Bednarski
المصدر: Molecules
Molecules, Vol 26, Iss 3658, p 3658 (2021)مصطلحات موضوعية: Plants, Medicinal, Plant Extracts, extractions, Organic chemistry, Antineoplastic Agents, Antineoplastic Agents, Phytogenic, Article, Inhibitory Concentration 50, QD241-441, Cell Line, Tumor, Humans, cytotoxicity, cancer, Ethiopia, Medicine, African Traditional, medicinal plants
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a6534f319759ceadee5ae7819a95640dTest
http://europepmc.org/articles/PMC8232819Test -
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المؤلفون: Martin Napierkowski, Lisa Wolff, Siva Sankar Murthy Bandaru, Claudia Urbainsky, Steven Behnisch‐Cornwell, Carola Schulzke, Christopher Horst Lillig, Muhammad Zubair, Patrick J. Bednarski
المصدر: Chemmedchem
مصطلحات موضوعية: GPX1, Thioredoxin reductase, Glutathione reductase, DNA fragmentation, Apoptosis, medicine.disease_cause, 01 natural sciences, Biochemistry, chemistry.chemical_compound, Glutathione Peroxidase GPX1, Heterocyclic Compounds, Drug Discovery, Tumor Cells, Cultured, General Pharmacology, Toxicology and Pharmaceutics, Enzyme Inhibitors, chemistry.chemical_classification, Membrane Potential, Mitochondrial, biology, Full Paper, Molecular Structure, Chemistry, Glutathione peroxidase, Full Papers, Molecular Medicine, cytotoxicity, Cell Survival, Antineoplastic Agents, Sulfides, Superoxide dismutase, Structure-Activity Relationship, Very Important Paper, medicine, Humans, Cell Proliferation, Pharmacology, Reactive oxygen species, Glutathione Peroxidase, pentathiepin, Dose-Response Relationship, Drug, 010405 organic chemistry, Organic Chemistry, Glutathione, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Oxidative Stress, biology.protein, cancer cells, Drug Screening Assays, Antitumor, Oxidative stress
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ccc766db533f3ed3c5850477407fbc9Test
https://pubmed.ncbi.nlm.nih.gov/32311219Test -
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المؤلفون: Florence N, Mbaoji, Steven, Behnisch-Cornwell, Adaobi C, Ezike, Chukwuemeka S, Nworu, Patrick J, Bednarski
المصدر: Molecules
مصطلحات موضوعية: HepG2, SiSo, leaf, Plant Extracts, Anacardiaceae, stem bark, KYSE 70, Antineoplastic Agents, Lannea barteri, Cell Cycle Checkpoints, Hep G2 Cells, Antioxidants, Article, Plant Leaves, adherent human carcinoma cell lines, Neoplasms, Plant Bark, Humans, Cell Proliferation
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::f8dd2c48fbd14f19130bb0705acd7721Test
https://pubmed.ncbi.nlm.nih.gov/32075139Test -
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المصدر: Metallomics. 10:323-336
مصطلحات موضوعية: 0301 basic medicine, Programmed cell death, Stereochemistry, Biophysics, Antineoplastic Agents, Apoptosis, In Vitro Techniques, Naphthalenes, Biochemistry, Biomaterials, 03 medical and health sciences, 0302 clinical medicine, Coordination Complexes, Tumor Cells, Cultured, medicine, Humans, Cytotoxic T cell, Cytotoxicity, Cell Proliferation, Platinum, Cisplatin, Molecular Structure, Chemistry, Cell Cycle, Metals and Alloys, Stereoisomerism, DNA, Burkitt Lymphoma, In vitro, 030104 developmental biology, Drug Resistance, Neoplasm, Chemistry (miscellaneous), Cell culture, 030220 oncology & carcinogenesis, G1 phase, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55ba5b16cf2f58b1fcf4cca5fdbadd65Test
https://doi.org/10.1039/c7mt00237hTest -
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المؤلفون: Katharina Korpis, Valentina Dal Col, Patrick J. Bednarski, Stefanie Brune, Dirk Schepmann, Bernhard Wünsch, Frauke Weber, Sabrina Pricl, Erik Laurini
المساهمون: Frauke, Weber, Steffi, Brune, Katharina, Korpi, Patrick J., Bednarski, Laurini, Erik, DAL COL, Valentina, Pricl, Sabrina, Dirk, Schepmann, Bernhard, Wünsch
المصدر: Journal of Medicinal Chemistry. 57:2884-2894
مصطلحات موضوعية: Models, Molecular, Stereochemistry, Guinea Pigs, sigma receptors, computer assisted drug design, Antineoplastic Agents, Apoptosis, Plasma protein binding, Molecular Dynamics Simulation, Piperazines, Structure-Activity Relationship, Neoplasms, Drug Discovery, Tumor Cells, Cultured, Animals, Humans, Receptors, sigma, Structure–activity relationship, Homology modeling, sigma receptor, Receptor, Molecular Structure, Chemistry, Brain, Ligand (biochemistry), Affinities, Cell culture, Molecular Medicine, Chromatography, Thin Layer, Protein Binding
وصف الملف: STAMPA
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de21ded4a7d95a96339e4c5711ed5b77Test
https://doi.org/10.1021/jm401707tTest -
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المؤلفون: Carsten Lange, Frauke Weber, Patrick J. Bednarski, Maurizio Fermeglia, Bernhard Wünsch, Dirk Schepmann, Frederik Börgel, Stefanie Brune, Erik Laurini, Sabrina Pricl, Katharina Korpis
المصدر: Journal of Medicinal Chemistry. 59:5505-5519
مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Stereochemistry, Guinea Pigs, Antineoplastic Agents, Apoptosis, Ligands, Heterocyclic Compounds, 2-Ring, Piperazines, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, Drug Discovery, medicine, Animals, Humans, Receptors, sigma, Structure–activity relationship, Receptor, Cell Proliferation, Sigma-1 receptor, Dose-Response Relationship, Drug, Molecular Structure, Bicyclic molecule, Cell growth, Chemistry, Ligand, Biological activity, 030104 developmental biology, Mechanism of action, 030220 oncology & carcinogenesis, Thermodynamics, Molecular Medicine, Drug Screening Assays, Antitumor, medicine.symptom
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcf03d726ba597ffbd869cae9faec2cbTest
https://doi.org/10.1021/acs.jmedchem.6b00585Test -
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المؤلفون: Łukasz Balewski, Anna Makowska, Patrick J. Bednarski, Franciszek Sączewski, Jarosław Sączewski
المصدر: Molecules
Volume 23
Issue 7
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules, Vol 23, Iss 7, p 1616 (2018)مصطلحات موضوعية: Acetonitriles, in vitro anticancer activity, Cell Survival, Pharmaceutical Science, Antineoplastic Agents, hybrid molecules, 2-imino-2H-chromen-3-yl-1,3,5-triazines, 01 natural sciences, Medicinal chemistry, Article, Analytical Chemistry, lcsh:QD241-441, Structure-Activity Relationship, lcsh:Organic chemistry, Cell Line, Tumor, Drug Discovery, Molecule, Cytotoxic T cell, Humans, Physical and Theoretical Chemistry, 2H-chromen-3-yl-1,3,5-triazines, Cell Proliferation, Aqueous solution, coumarins, Molecular Structure, 010405 organic chemistry, Chemistry, Triazines, Organic Chemistry, In vitro, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Chemistry (miscellaneous), Molecular Medicine, Drug Screening Assays, Antitumor, 2,4-diamino-1,3,5-triazines, 2-imino-coumarins, Human cancer
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a11ebb75ee043406f268c45df00d31Test
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المصدر: Molecules
Volume 23
Issue 6
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules, Vol 23, Iss 6, p 1497 (2018)مصطلحات موضوعية: quinolines, synthesis, Cell Survival, Pharmaceutical Science, Antineoplastic Agents, 1,2,4-triazoles, Ring (chemistry), 01 natural sciences, Medicinal chemistry, Article, Analytical Chemistry, lcsh:QD241-441, chemistry.chemical_compound, Structure-Activity Relationship, lcsh:Organic chemistry, Cell Line, Tumor, Drug Discovery, N-sulfonylhydrazones, in vitro antitumor activity, Moiety, Humans, structure, Physical and Theoretical Chemistry, Methylene, N-acylhydrazones, Benzotriazole, 010405 organic chemistry, Organic Chemistry, Quinoline, 1,2,4-Triazole, Triazoles, In vitro, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry, Chemistry (miscellaneous), Drug Design, Molecular Medicine, Chemical stability, hydrazones, 1,2,3-benzotriazoles
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::093c8a146fc70d3fa15ac84e61a5dd67Test