المؤلفون: Akihiko Ito, Mitsuo Hashimoto, Jun Tanihata, Sachi Matsubayashi, Ryoko Sasaki, Shota Fujimoto, Hironori Kawamoto, Yusuke Hosaka, Akihiro Ichikawa, Tsukasa Kadota, Yu Fujita, Daisuke Takekoshi, Sabro Ito, Shunsuke Minagawa, Takanori Numata, Hiromichi Hara, Tatsuki Matsuoka, Jun Udaka, Jun Araya, Mitsuru Saito, Kazuyoshi Kuwano

المصدر: Journal of cachexia, sarcopenia and muscle, vol 13, iss 3

مصطلحات موضوعية: Chronic Obstructive, Sarcopenia, Physiology, Chronic Obstructive Pulmonary Disease, Ubiquitin-Protein Ligases, Clinical Sciences, Inbred C57BL, Pulmonary Disease, Mice, Pulmonary Disease, Chronic Obstructive, Physiology (medical), Tobacco, COPD, 2.1 Biological and endogenous factors, Animals, Humans, Orthopedics and Sports Medicine, Aetiology, Lung, Parkin, Tobacco Smoke and Health, Mitophagy, Cigarette smoke, Human Movement and Sports Sciences, Mice, Inbred C57BL, Muscular Atrophy, Muscle contraction, Musculoskeletal, Respiratory, Muscle atrophy, Reactive Oxygen Species

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::836b17d140afd74d6b92f04956af1d18Test
https://pubmed.ncbi.nlm.nih.gov/35373498Test

المؤلفون: Tsukasa Kadota, Kenji Kobayashi, Yusuke Kurita, Saburo Ito, Katsutoshi Nakayama, Hiromichi Hara, Makoto Odaka, Takanori Numata, Hiroshi Wakui, Yumi Kaneko, Kazuya Tsubouchi, Shohei Mori, Akihiro Ichikawa, Makoto Yamashita, Yusuke Hosaka, Shunsuke Minagawa, Hirotaka Imai, Hisatoshi Asano, Kazuyoshi Kuwano, Nayuta Saito, Nahoko Sato, Masahiro Yoshida, Toshiaki Morikawa, Taro Sakamoto, Hirohumi Utsumi, Jun Araya, Takeo Iwamoto

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, General Physics and Astronomy, 02 engineering and technology, GPX4, medicine.disease_cause, Pathogenesis, Lipid peroxidation, chemistry.chemical_compound, Pulmonary Disease, Chronic Obstructive, lcsh:Science, Phospholipids, COPD, Multidisciplinary, biology, Chronic obstructive pulmonary disease, Smoking, respiratory system, 021001 nanoscience & nanotechnology, Deferoxamine, 0210 nano-technology, medicine.drug, Cell death, Programmed cell death, Iron, Science, Nuclear Receptor Coactivators, Mice, Transgenic, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, medicine, Animals, Ferroptosis, Humans, business.industry, Epithelial Cells, General Chemistry, medicine.disease, respiratory tract diseases, Ferritin, Mice, Inbred C57BL, 030104 developmental biology, chemistry, biology.protein, Cancer research, lcsh:Q, Lipid Peroxidation, business, Reactive Oxygen Species, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::841b34bc8bc50cc9523737c8cc820ffeTest
https://doaj.org/article/7f973dabdbee4e05bfa82fda5c334da7Test

المؤلفون: Mi So Kim, Ae-Rin Baek, Ji Min Lee, Do Jin Kim, Shunsuke Minagawa, Masahiro Yoshida, Su Sie Chin, An Soo Jang, Choon-Sik Park, Sung Woo Park, June-Hyuk Lee, Jun Araya, Kazuyoshi Kuwano

المصدر: American Journal of Respiratory Cell and Molecular Biology. 59:215-224

مصطلحات موضوعية: 0301 basic medicine, Pulmonary and Respiratory Medicine, Programmed cell death, Necroptosis, Clinical Biochemistry, Apoptosis, Kidney, Bleomycin, Pathogenesis, Mice, Necrosis, 03 medical and health sciences, chemistry.chemical_compound, Idiopathic pulmonary fibrosis, 0302 clinical medicine, Fibrosis, medicine, Animals, Humans, Molecular Biology, Lung, Caspase 3, business.industry, Graft Survival, Epithelial Cells, Cell Biology, respiratory system, medicine.disease, respiratory tract diseases, 030104 developmental biology, medicine.anatomical_structure, chemistry, Receptor-Interacting Protein Serine-Threonine Kinases, 030220 oncology & carcinogenesis, Cancer research, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::628e6e52d56d96daf1247c27d3c1a5e9Test
https://doi.org/10.1165/rcmb.2017-0034ocTest

المؤلفون: Jun Araya, Takahiro Ochiya, Takashi Ohtsuka, Shunsuke Minagawa, Hironori Kawamoto, Yu Fujita, Hiromichi Hara, Yusuke Yamamoto, Kazuyoshi Kuwano, Tsukasa Kadota, Naoaki Watanabe, Shota Fujimoto

المصدر: Journal of Extracellular Vesicles
Journal of Extracellular Vesicles, Vol 10, Iss 10, Pp n/a-n/a (2021)

مصطلحات موضوعية: Histology, senescence, Biology, Exosome, Wnt-5a Protein, Idiopathic pulmonary fibrosis, Extracellular Vesicles, Mice, Fibrosis, Transforming Growth Factor beta, Proto-Oncogene Proteins, Wnt3A Protein, Pulmonary fibrosis, medicine, Animals, Humans, exosome, Wnt Signaling Pathway, Cells, Cultured, Cellular Senescence, Research Articles, mesenchymal stem cell, QH573-671, pulmonary fibrosis, Wnt signaling pathway, Cell Differentiation, Epithelial Cells, Mesenchymal Stem Cells, Cell Biology, Extracellular vesicle, medicine.disease, Idiopathic Pulmonary Fibrosis, Mice, Inbred C57BL, Wnt Proteins, MicroRNAs, Cancer research, Cytology, Myofibroblast, lung epithelial cell, Transforming growth factor, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e95812b0e698567d2f88fdb32561c283Test
https://pubmed.ncbi.nlm.nih.gov/34377373Test

المؤلفون: Shigehiro Yagishita, Shota Fujimoto, Akihiro Ichikawa, Tsukasa Kadota, Jun Araya, Shunsuke Minagawa, Yusuke Yamamoto, Yu Fujita, Akihiko Ito, Hiromichi Hara, Hironori Kawamoto, Mitsuo Hashimoto, Yusuke Hosaka, Noriko Motoi, Naoaki Watanabe, Nayuta Saito, Takahiro Ochiya, Kazuyoshi Kuwano, Masahiro Yoshida

المصدر: Cancer Science

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Programmed cell death, Lung Neoplasms, Gene Expression, LAMP2A, 03 medical and health sciences, 0302 clinical medicine, Chaperone-mediated autophagy, Downregulation and upregulation, Cell, Molecular, and Stem Cell Biology, chaperone‐mediated autophagy, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Lysosomal-Associated Membrane Protein 2, medicine, Biomarkers, Tumor, Animals, Humans, health care economics and organizations, Cell Proliferation, Cell growth, Chemistry, Intrinsic apoptosis, Autophagy, apoptosis, Cancer, chemoresistance, General Medicine, Original Articles, medicine.disease, Prognosis, Immunohistochemistry, humanities, respiratory tract diseases, lung cancer, 030104 developmental biology, Oncology, Apoptosis, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Gene Knockdown Techniques, Proteolysis, Cancer research, Original Article, Lysosomes, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::616b207a3b1cc1b20236e8ac2e65e8baTest
https://pubmed.ncbi.nlm.nih.gov/32860290Test

المؤلفون: Masahiro Yoshida, Hiromichi Hara, Jun Araya, Shunsuke Minagawa, Hirotaka Imai, Kazuyoshi Kuwano

المصدر: American journal of respiratory cell and molecular biology. 62(5)

مصطلحات موضوعية: 0301 basic medicine, Pulmonary and Respiratory Medicine, Lung Diseases, Cell type, Programmed cell death, Necroptosis, Clinical Biochemistry, Context (language use), Biology, 03 medical and health sciences, Necrosis, 0302 clinical medicine, Autophagy, Alarmins, Animals, Ferroptosis, Humans, Protein kinase A, Molecular Biology, chemistry.chemical_classification, Reactive oxygen species, Effector, Cell Biology, Cell biology, 030104 developmental biology, 030228 respiratory system, chemistry

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df0c16be92039eb7eb5e421a92d28e00Test
https://pubmed.ncbi.nlm.nih.gov/32017592Test

المؤلفون: Takahiro Ochiya, Tsukasa Kadota, Kazuyoshi Kuwano, Yu Fujita, Jun Araya

المصدر: American Journal of Respiratory Cell and Molecular Biology. 58:560-565

مصطلحات موضوعية: Lung Diseases, 0301 basic medicine, Pulmonary and Respiratory Medicine, Clinical Biochemistry, Antigen presentation, Inflammation, Biology, Exosomes, Proinflammatory cytokine, 03 medical and health sciences, Paracrine signalling, 0302 clinical medicine, Immune system, Immunity, medicine, Animals, Humans, Lung, Molecular Biology, Cell Biology, Microvesicles, Cell biology, MicroRNAs, 030104 developmental biology, Tumor Escape, 030220 oncology & carcinogenesis, Host-Pathogen Interactions, Inflammation Mediators, medicine.symptom, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef8fca71f713a4057e638013d375f454Test
https://doi.org/10.1165/rcmb.2017-0293trTest

المؤلفون: Tsukasa Kadota, Nahoko Sato, Kenji Kobayashi, Hiroshi Wakui, Toshiaki Morikawa, Yoichi Nakanishi, Makoto Yamashita, Takeo Ishikawa, Hirofumi Utsumi, Kazuyoshi Kuwano, Yu Fujita, Makoto Odaka, Yumi Kaneko, Saburo Ito, Mitsuo Hashimoto, Katsutoshi Nakayama, Kazuya Tsubouchi, Haruhiko Yanagisawa, Jun Araya, Hisatoshi Asano, Shunsuke Minagawa, Hiromichi Hara, Yusuke Kurita, Masahiro Yoshida, Yutaka Yoshii, Nayuta Saito, Takanori Numata, Akihiro Ichikawa

المصدر: Autophagy. 13:1420-1434

مصطلحات موضوعية: 0301 basic medicine, Proteasome Endopeptidase Complex, Translational Research Paper, Ubiquitin-Protein Ligases, Azithromycin, Biology, Bleomycin, Models, Biological, Transforming Growth Factor beta1, 03 medical and health sciences, Idiopathic pulmonary fibrosis, chemistry.chemical_compound, Fibrosis, medicine, Animals, Humans, Myofibroblasts, Lung, Molecular Biology, urogenital system, Autophagy, Ubiquitination, NOX4, Cell Differentiation, Cell Biology, medicine.disease, Idiopathic Pulmonary Fibrosis, Mitochondria, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, Proteostasis, chemistry, NADPH Oxidase 4, Proteolysis, Immunology, Unfolded Protein Response, Cancer research, Reactive Oxygen Species, Myofibroblast, Transforming growth factor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3ce4d718f81443200fa75afe89021a2Test
https://doi.org/10.1080/15548627.2017.1328348Test

المؤلفون: Kazuya Tsubouchi, Takanori Numata, Saburo Ito, Masahiro Yoshida, Hiromichi Hara, Yoichi Nakanishi, Hideki Matsudaira, Yusuke Hosaka, Akihiro Ichikawa, Hisatoshi Asano, Katsutoshi Nakayama, Takashi Ohtsuka, Yu Fujita, Nayuta Saito, Yumi Kaneko, Hirofumi Utsumi, Shunsuke Minagawa, Hirotaka Imai, Kenji Kobayashi, Mitsuo Hashimoto, Taro Sakamoto, Hiroshi Wakui, Yusuke Kurita, Tsukasa Kadota, Shohei Mori, Tomoko Koumura, Kazuyoshi Kuwano, Jun Araya

المصدر: Journal of immunology (Baltimore, Md. : 1950). 203(8)

مصطلحات موضوعية: Immunology, Mice, Transgenic, GPX4, Bleomycin, Lipid peroxidation, Pathogenesis, Idiopathic pulmonary fibrosis, chemistry.chemical_compound, Mice, Transforming Growth Factor beta, medicine, Immunology and Allergy, Animals, Humans, Myofibroblasts, Cells, Cultured, Mice, Knockout, Lung, business.industry, Cell Differentiation, Glutathione, respiratory system, medicine.disease, Phospholipid Hydroperoxide Glutathione Peroxidase, Idiopathic Pulmonary Fibrosis, respiratory tract diseases, Mice, Inbred C57BL, Disease Models, Animal, medicine.anatomical_structure, chemistry, Cancer research, Lipid Peroxidation, business, Myofibroblast

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9fd07db76c656098b92975403c6cbb5Test
https://pubmed.ncbi.nlm.nih.gov/31534007Test

المؤلفون: Hirofumi Utsumi, Jun Kojima, Mitsuo Hashimoto, Haruhiko Yanagisawa, Kenji Kobayashi, Yu Fujita, Yusuke Kurita, Kenichiro Shimizu, Naoki Takasaka, Jun Araya, Masahiro Yoshida, Hisatoshi Asano, Makoto Yamashita, Makoto Odaka, Kazuya Tsubouchi, Nahoko Sato, Nayuta Saito, Makoto Kawaishi, Shunsuke Minagawa, Takanori Numata, Hiroshi Wakui, Katsutoshi Nakayama, Saburo Ito, Yumi Kaneko, Tsukasa Kadota, Hiromichi Hara, Kazuyoshi Kuwano, Toshiaki Morikawa

المصدر: The Journal of Immunology. 197:504-516

مصطلحات موضوعية: 0301 basic medicine, Ubiquitin-Protein Ligases, Cellular differentiation, Blotting, Western, Immunology, Fluorescent Antibody Technique, Biology, Mice, Phosphatidylinositol 3-Kinases, 03 medical and health sciences, 0302 clinical medicine, Microscopy, Electron, Transmission, Growth factor receptor, Fibrosis, Mitophagy, In Situ Nick-End Labeling, medicine, Animals, Humans, Immunology and Allergy, Receptors, Platelet-Derived Growth Factor, Myofibroblasts, Protein kinase B, PI3K/AKT/mTOR pathway, Mice, Knockout, Autophagy, Cell Differentiation, respiratory system, medicine.disease, Immunohistochemistry, Idiopathic Pulmonary Fibrosis, respiratory tract diseases, 030104 developmental biology, 030220 oncology & carcinogenesis, Cancer research, Proto-Oncogene Proteins c-akt, Myofibroblast, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::995e6c6fce5605ecd297297cddd6e1eeTest
https://doi.org/10.4049/jimmunol.1600265Test