المؤلفون: Thomaston, Jessica L, Wu, Yibing, Polizzi, Nicholas, Liu, Lijun, Wang, Jun, DeGrado, William F

المصدر: Journal of the American Chemical Society. 141(29)

مصطلحات موضوعية: Chemical Sciences, Influenza, Prevention, Emerging Infectious Diseases, Pneumonia & Influenza, Infectious Diseases, Adamantane, Amantadine, Asparagine, Binding Sites, Crystallography, X-Ray, Drug Resistance, Viral, Hydrogen Bonding, Hydrogen-Ion Concentration, Influenza A virus, Models, Molecular, Nuclear Magnetic Resonance, Biomolecular, Protein Conformation, Viral Matrix Proteins, General Chemistry, Chemical sciences, Engineering

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/6rg09757Test

المؤلفون: Hu, Yanmei, Musharrafieh, Rami, Ma, Chunlong, Zhang, Jiantao, Smee, Donald F, DeGrado, William F, Wang, Jun

مصطلحات موضوعية: Biological Sciences, Biomedical and Clinical Sciences, Microbiology, Clinical Sciences, Medical Microbiology, Infectious Diseases, Influenza, Prevention, Antimicrobial Resistance, Pneumonia & Influenza, Vaccine Related, Emerging Infectious Diseases, Biodefense, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Infection, Adamantane, Amantadine, Animals, Antiviral Agents, Dogs, Drug Resistance, Viral, Humans, Influenza A virus, Influenza, Human, Inhibitory Concentration 50, Madin Darby Canine Kidney Cells, Molecular Dynamics Simulation, Mutation, Orthomyxoviridae Infections, Spiro Compounds, Structure-Activity Relationship, Viral Matrix Proteins, Influenza virus, M2 proton channel, V27A Drug resistance, Spiroadamantane, Antiviral, Drug resistance, V27A, Pharmacology and Pharmaceutical Sciences, Virology, Medical microbiology, Pharmacology and pharmaceutical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/00x7v6msTest

المؤلفون: Thomaston, Jessica L, DeGrado, William F

المصدر: Protein Science. 25(8)

مصطلحات موضوعية: Biochemistry and Cell Biology, Medicinal and Biomolecular Chemistry, Chemical Sciences, Biological Sciences, Influenza, Infectious Diseases, Pneumonia & Influenza, Prevention, Biodefense, Emerging Infectious Diseases, Vaccine Related, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Infection, Amantadine, Antiviral Agents, Asparagine, Crystallization, Crystallography, X-Ray, Drug Resistance, Viral, Gene Expression, Hydrogen Bonding, Influenza A virus, Models, Molecular, Mutation, Protein Binding, Protons, Serine, Viral Matrix Proteins, influenza M2, S31N, proton channel, crystal structure, Computation Theory and Mathematics, Other Information and Computing Sciences, Biophysics, Biochemistry and cell biology, Medicinal and biomolecular chemistry

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/3c9856xvTest

المؤلفون: Ghosh, Ayanjeet, Wang, Jun, Moroz, Yurii S, Korendovych, Ivan V, Zanni, Martin, DeGrado, William F, Gai, Feng, Hochstrasser, Robin M

المصدر: The Journal of Chemical Physics. 140(23)

مصطلحات موضوعية: Pneumonia & Influenza, Influenza, Emerging Infectious Diseases, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Amantadine, Binding Sites, Diffusion, Humans, Influenza A virus, Influenza, Human, Molecular Dynamics Simulation, Protons, Spectrophotometry, Infrared, Water, Physical Sciences, Chemical Sciences, Engineering, Chemical Physics

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/06k6653cTest

المؤلفون: Rey-Carrizo, Matias, Torres, Eva, Ma, Chunlong, Barniol-Xicota, Marta, Wang, Jun, Wu, Yibing, Naesens, Lieve, DeGrado, William F, Lamb, Robert A, Pinto, Lawrence H, Vázquez, Santiago

المصدر: Journal of Medicinal Chemistry. 56(22)

مصطلحات موضوعية: Emerging Infectious Diseases, Prevention, Vaccine Related, Pneumonia & Influenza, Influenza, Infectious Diseases, Biodefense, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Infection, Amantadine, Animals, Antiviral Agents, Aza Compounds, Bridged-Ring Compounds, Dogs, Drug Design, Drug Resistance, Viral, Guanidines, Influenza A Virus, H1N1 Subtype, Influenza A Virus, H3N2 Subtype, Inhibitory Concentration 50, Madin Darby Canine Kidney Cells, Mutation, Pyrrolidines, Structure-Activity Relationship, Viral Matrix Proteins, Medicinal and Biomolecular Chemistry, Organic Chemistry, Pharmacology and Pharmaceutical Sciences, Medicinal & Biomolecular Chemistry

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/1kn880m5Test

المؤلفون: Williams, Jonathan K, Tietze, Daniel, Wang, Jun, Wu, Yibing, DeGrado, William F, Hong, Mei

المصدر: Journal of the American Chemical Society. 135(26)

مصطلحات موضوعية: Emerging Infectious Diseases, Infectious Diseases, Pneumonia & Influenza, Influenza, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Infection, Amantadine, Ion Channels, Isoxazoles, Models, Molecular, Molecular Dynamics Simulation, Molecular Structure, Mutation, Nuclear Magnetic Resonance, Biomolecular, Protein Conformation, Viral Matrix Proteins, Chemical Sciences, General Chemistry

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/0kh6b4m6Test

المؤلفون: Yi, Myunggi, Cross, Timothy A., Zhou, Huan-Xiang, DeGrado, William F.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2009 Aug 01. 106(32), 13311-13316.

الوصول الحر: https://www.jstor.org/stable/40485363Test

المؤلفون: Balgi, Aruna D., Wang, Jun, Cheng, Daphne Y. H., Ma, Chunlong, Pfeifer, Tom A., Shimizu, Yoko, Anderson, Hilary J., Pinto, Lawrence H., Lamb, Robert A., DeGrado, William F., Roberge, Michel

المصدر: PLoS ONE; Feb2013, Vol. 8 Issue 2, p1-9, 9p

مصطلحات موضوعية: INFLUENZA A virus, PROTEINS, ANTIVIRAL agents, INFLUENZA treatment, AMANTADINE, VETERINARY microbiology, PHARMACEUTICAL chemistry

المؤلفون: Jun Wang, Yibing Wu, Chunlong Ma, Fiorin, Giacomo, Jizhou Wang, Pinto, Lawrence H., Lamb, Robert A., Klein, Michael L., DeGrado, William F.

المصدر: Proceedings of the National Academy of Sciences of the United States of America; 1/22/2013, Vol. 110 Issue 4, p1315-1320, 6p

مصطلحات موضوعية: INFLUENZA A virus, AMANTADINE, MEMBRANE proteins, MOLECULAR dynamics, NUCLEAR magnetic resonance

المؤلفون: Ghosh, Ayanjeet, Qiu, Jade, DeGrado, William F., Hochstrasser, Robin M.

المصدر: Proceedings of the National Academy of Sciences of the United States of America; 4/12/2011, Vol. 108 Issue 15, p6115-6120, 6p

مصطلحات موضوعية: PROTONS, INFLUENZA A virus, CARBONYL compounds, FEMTOSECOND lasers, HYDROGEN bonding, AMANTADINE