Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
| العنوان: | Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes |
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| المؤلفون: | Jan A.K.W. Kiel, Marianne M. Laporte, Yasuo Uchiyama, Lesya V. Tumanovska, Paula I. Moreira, Ray Truant, Russell L. Deter, Corinne Clavé, Xiongwei Zhu, Carlos López-Otín, Katharina Spanel-Borowski, Xuejun Jiang, David Kessel, William A. Dunn, Clark W. Distelhorst, Eeva-Liisa Eskelinen, Fu-Cheng Lin, Michele S. Swanson, Michael Thumm, You-Wen He, Alexei Terman, Leroy F. Liu, Hans-Uwe Simon, Marco Sandri, Thomas P. Neufeld, Per E. Stromhaug, Eva C. Vaquero, Janice S. Blum, Graham S. Taylor, David S. Askew, Giovanni Miotto, Michael Duszenko, Bruce A. Bamber, Marian DiFiglia, William T. Jackson, Katsuhiko Kitamoto, Bernd Nürnberg, J. Fred Dice, Chihiro Sasakawa, John J. Shacka, Attila L. Kovács, Kozo Fujisaki, Michael Moore, Savithramma P. Dinesh-Kumar, Ameeta Kelekar, David A. Gewirtz, Augustine M.K. Choi, Kah-Leong Lim, Bulent Ozpolat, Masaaki Komatsu, Kirill Kiselyov, Wilfried Bursch, Gianluca Tettamanti, Craig B. Thompson, Spencer B. Gibson, Takashi Ueno, Diane C. Bassham, Chanhee Kang, Mark A. Smith, Laura J. Olsen, Pyo Kim Hong, Michael J. Lenardo, Shengkan Jin, Patrick B. Dennis, Aviva M. Tolkovsky, Sharon M. Gorski, Gabriel Lopez-Berestein, Daniel J. Klionsky, Patrice Codogno, Antje Gohla, Hiroshi Sakagami, Terje Johansen, Yasuyoshi Sakai, Junichi Sadoshima, Takeshi Noda, José M. Fuentes, Michisuke Yuzaki, Mauro Piacentini, Michel Dron, Gutian Xiao, Frank C. Dorsey, Josef Mautner, Isei Tanida, Miklós Sass, John H. Brumell, Olga Zabirnyk, Francesco Cecconi, David C. Rubinsztein, Wim Martinet, Jeffrey Settleman, Sharon A. Tooze, Audrey Esclatine, John L. Cleveland, Kozo Tanaka, James M. Cregg, Jayanta Debnath, Leon Murphy, Oleksandr Seleverstov, Kay F. Macleod, Maria Høyer-Hansen, Naweed I. Naqvi, Ramon Gonzalez, Akiko Iwasaki, Ira Tabas, Patrizia Agostinis, Willisa Liou, Christian Münz, Michinaga Ogawa, Li Yu, Wulf Dröge, Huan Yao Lei, Baharia Mograbi, Meredith A. Steeves, Bo Lu, Marja Jäättelä, Ken Matsuoka, Ulf T. Brunk, Tassula Proikas-Cezanne, Robert S. B. Clark, Kevin M. Ryan, Harald Stenmark, Iryna Monastyrska, Jacques Landry, Ben A. Bahr, Mojgan Djavaheri-Mergny, Hong Gang Wang, Tomasz Motyl, Juan Fueyo, Vojo Deretic, Hagai Abeliovich, George S. Yap, László Fésüs, Paul A.M. Michels, John W. Wiley, Martine Biard-Piechaczyk, Xun Hu, Xiaoxiang Zheng, Wilhelm P. Mistiaen, Steven Clarke, Roberta A. Gottlieb, Kim A. Heidenreich, Seiji Kondo, Paul Webster, Fulvio Reggiori, Irving M. Shapiro, Carlos S. Subauste, Zsolt Tallóczy, Ichizo Nishino, Ettore Bergamini, Vickram Srinivas, Shoshana Paglin, Andrea Ballabio, Federica Di Sano, Nicholas J. Talbot, María Isabel Colombo, Zvulun Elazar, Dieter Häussinger, Chia Yi Kuan, Tibor Vellai, Anne Simonsen, Nancy L. Oleinick, Fen-Biao Gao, Jae U. Jung, Seiichiro Sugimoto, Gjumrakch Aliev, Abdelhaq Rami, Issidora S. Papassideri, Eduardo Cebollero, Beth Levine, N. Tony Eissa, David H. Perlmutter, Weidong Le, Wei-Pang Huang, Phillip A. Dennis, Joseph A. Hill, Michael W. Vogel, Charleen T. Chu, Noboru Mizushima, Walter Malorni, Brigitte Galliot, Andrew P. Lieberman, Erwin Knecht, Joachim Yahalom, Alfred L. Goldberg, Devendra K. Agrawal, Fumihiko Takeshita, Rodney J. Devenish, Keiji Tanaka, Lih-Shen Chin, Crisfiano Simone, Xiaoning Bi, David Sulzer, Zhijun Xi, Misuzu Baba, Andrei A. Sibirny, Elaine C.M. Silva-Zacarin, Guido Kroemer, Kim D. Finley, George Perry, Glen E. Palmer, Néstor L. Uzcátegui, Ana Coto-Montes, Ida J. van der Klei, Cristina González-Estévez, Xiao Ming Yin, Yingyu Chen, J. Paul Taylor, Alfred J. Meijer, Yuji Moriyasu, Jongkyeong Chung, Rakesh Kumar, Nadine Camougrand, Timothy J. Kinsella, Dale E. Bredesen, Bärbel Rohrer, Jeffrey L. Brodsky, Eiki Kominami, Ana Maria Cuervo, Adi Kimchi, Mondira Kundu, Peter G.H. Clarke, Zhenyu Yue, Ronit Pinkas-Kramarski, Per Ottar Seglen, Mark Prescott, Toshihiko Suzuki, Miles Parkes, Eric H. Baehrecke, Alicia Meléndez, Tamotsu Yoshimori, Claudio Schneider, Jin Ming Yang, Nina Raben, Francesca Demarchi, Ralph A. Nixon, Motoni Kadowaki |
| المصدر: | Europe PubMed Central Autophagy Scopus-Elsevier CIÊNCIAVITAE ResearcherID r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF) instname r-CIPF: Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF) Centro de Investigación Principe Felipe (CIPF) Autophagy, vol. 4, no. 2, pp. 151-175 RIUR. Repositorio Institucional de la Universidad de La Rioja Autophagy 4, 151-175 (2008) Klionsky, D J, Abeliovich, H, Agostinis, P, Agrawal, D K, Aliev, G, Askew, D S, Baba, M, Baehrecke, E H, Bahr, B A, Ballabio, A, Bamber, B A, Bassham, D C, Bergamini, E, Bi, X, Biard-Piechaczyk, M, Blum, J S, Bredesen, D E, Brodsky, J L, Brumell, J H, Brunk, U T, Bursch, W, Camougrand, N, Cebollero, E, Cecconi, F, Chen, Y, Chin, L-S, Choi, A, Chu, C T, Chung, J, Clarke, P G H, Clark, R S B, Clarke, S G, Clavé, C, Cleveland, J L, Codogno, P, Colombo, M I, Coto-Montes, A, Cregg, J M, Cuervo, A M, Debnath, J, Demarchi, F, Dennis, P B, Dennis, P A, Deretic, V, Devenish, R J, Di Sano, F, Dice, J F, Difiglia, M, Dinesh-Kumar, S, Distelhorst, C W, Djavaheri-Mergny, M, Dorsey, F C, Dröge, W, Dron, M, Dunn, W A, Duszenko, M, Eissa, N T, Elazar, Z, Esclatine, A, Eskelinen, E-L, Fésüs, L, Finley, K D, Fuentes, J M, Fueyo, J, Fujisaki, K, Galliot, B, Gao, F-B, Gewirtz, D A, Gibson, S B, Gohla, A, Goldberg, A L, Gonzalez, R, González-Estévez, C, Gorski, S, Gottlieb, R A, Häussinger, D, He, Y-W, Heidenreich, K, Hill, J A, Høyer-Hansen, M, Hu, X, Huang, W-P, Iwasaki, A, Jäättelä, M, Jackson, W T, Jiang, X, Jin, S, Johansen, T, Jung, J U, Kadowaki, M, Kang, C, Kelekar, A, Kessel, D H, Kiel, J A K W, Kim, H P, Kimchi, A, Kinsella, T J, Kiselyov, K, Kitamoto, K, Knecht, E, Komatsu, M, Kominami, E, Kondo, S, Kovács, A L, Kroemer, G, Kuan, C-Y, Kumar, R, Kundu, M, Landry, J, Laporte, M, Le, W, Lei, H-Y, Lenardo, M J, Levine, B, Lieberman, A, Lim, K-L, Lin, F-C, Liou, W, Liu, L F, Lopez-Berestein, G, López-Otín, C, Lu, B, Macleod, K F, Malorni, W, Martinet, W, Matsuoka, K, Mautner, J, Meijer, A J, Meléndez, A, Michels, P, Miotto, G, Mistiaen, W P, Mizushima, N, Mograbi, B, Monastyrska, I, Moore, M N, Moreira, P I, Moriyasu, Y, Motyl, T, Münz, C, Murphy, L O, Naqvi, N I, Neufeld, T P, Nishino, I, Nixon, R A, Noda, T, Nürnberg, B, Ogawa, M, Oleinick, N L, Olsen, L J, Ozpolat, B, Paglin, S, Palmer, G E, Papassideri, I, Parkes, M, Perlmutter, D H, Perry, G, Piacentini, M, Pinkas-Kramarski, R, Prescott, M, Proikas-Cezanne, T, Raben, N, Rami, A, Reggiori, F, Rohrer, B, Rubinsztein, D C, Ryan, K M, Sadoshima, J, Sakagami, H, Sakai, Y, Sandri, M, Sasakawa, C, Sass, M, Schneider, C, Seglen, P O, Seleverstov, O, Settleman, J, Shacka, J J, Shapiro, I M, Sibirny, A, Silva-Zacarin, E C M, Simon, H-U, Simone, C, Simonsen, A, Smith, M A, Spanel-Borowski, K, Srinivas, V, Steeves, M, Stenmark, H, Stromhaug, P E, Subauste, C S, Sugimoto, S, Sulzer, D, Suzuki, T, Swanson, M S, Tabas, I, Takeshita, F, Talbot, N J, Tallóczy, Z, Tanaka, K, Tanaka, K, Tanida, I, Taylor, G S, Taylor, J P, Terman, A, Tettamanti, G, Thompson, C B, Thumm, M, Tolkovsky, A M, Tooze, S A, Truant, R, Tumanovska, L V, Uchiyama, Y, Ueno, T, Uzcátegui, N L, van der Klei, I, Vaquero, E C, Vellai, T, Vogel, M W, Wang, H-G, Webster, P, Wiley, J W, Xi, Z, Xiao, G, Yahalom, J, Yang, J-M, Yap, G, Yin, X-M, Yoshimori, T, Yu, L, Yue, Z, Yuzaki, M, Zabirnyk, O, Zheng, X, Zhu, X & Deter, R L 2008, ' Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes ', Autophagy, vol. 4, no. 2, pp. 151-75 . https://doi.org/10.4161/auto.5338Test |
| مصطلحات موضوعية: | Autophagosome, GLUCAGON-INDUCED AUTOPHAGY, VINBLASTINE-INDUCED AUTOPHAGOCYTOSIS, STARVATION-INDUCED AUTOPHAGY, Autolysosome, autophagosome, Flux, Lysosome, Phagophore, Stress, Vacuole, MURINE PANCREATIC ACINAR, stress, ISOLATED RAT HEPATOCYTES, SEMINAL-VESICLE CELLS, DROSOPHILA FAT-BODY, BETAINE HOMOCYSTEINE METHYLTRANSFERASE, ELECTRON MICROSCOPIC EXAMINATION, CHAPERONE-MEDIATED AUTOPHAGY, 0302 clinical medicine, Chaperone-mediated autophagy, Phagosomes, Plants/metabolism, 0303 health sciences, Autophagy database, Plants, Saccharomyces cerevisiae Proteins/metabolism, autolysosome, Cell biology, Protein Transport, Eukaryotic Cells, Data Interpretation, Statistical, 030220 oncology & carcinogenesis, Microtubule-Associated Proteins/metabolism, lysosome, Autophagy/physiology, Microtubule-Associated Proteins, Phagosomes/metabolism, autophagy, Autophagy-Related Protein 8 Family, Saccharomyces cerevisiae Proteins, Settore BIO/06, Guidelines as Topic, Computational biology, Biology, Models, Biological, Article, 03 medical and health sciences, Animals, Humans, Set (psychology), Molecular Biology, Microscopy, Fluorescence/methods, phagophore, 030304 developmental biology, Eukaryotic Cells/physiology, flux, vacuole, Interpretation (logic), Clinical Laboratory Techniques, Laboratory Techniques and Procedures, Phagosomes/physiology, Protein Processing, Post-Translational, Autophagy, Cell Biology, Microscopy, Fluorescence, Human medicine |
| الوصف: | Research in autophagy continues to accelerate,1and as a result many new scientists are entering the field. Accordingly, it is important to establish a standard set of criteria for monitoring macroautophagy in different organisms. Recent reviews have described the range of assays that have been used for this purpose.2,3There are many useful and convenient methods that can be used to monitor macroautophagy in yeast, but relatively few in other model systems, and there is much confusion regarding acceptable methods to measure macroautophagy in higher eukaryotes. A key point that needs to be emphasized is that there is a difference between measurements that monitor the numbers of autophagosomes versus those that measure flux through the autophagy pathway; thus, a block in macroautophagy that results in autophagosome accumulation needs to be differentiated from fully functional autophagy that includes delivery to, and degradation within, lysosomes (in most higher eukaryotes) or the vacuole (in plants and fungi). Here, we present a set of guidelines for the selection and interpretation of the methods that can be used by investigators who are attempting to examine macroautophagy and related processes, as well as by reviewers who need to provide realistic and reasonable critiques of papers that investigate these processes. This set of guidelines is not meant to be a formulaic set of rules, because the appropriate assays depend in part on the question being asked and the system being used. In addition, we emphasize that no individual assay is guaranteed to be the most appropriate one in every situation, and we strongly recommend the use of multiple assays to verify an autophagic response. ©2008 Landes Bioscience. |
| وصف الملف: | pdf; application/pdf |
| تدمد: | 1554-8627 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c3f52fead4a8312d44d281412603b27Test http://europepmc.org/abstract/med/18188003Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....7c3f52fead4a8312d44d281412603b27 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15548627 |
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