دورية أكاديمية
Worse cardiovascular prognosis after endovascular surgery for intermittent claudication caused by infrainguinal atherosclerotic disease in patients with diabetes
| العنوان: | Worse cardiovascular prognosis after endovascular surgery for intermittent claudication caused by infrainguinal atherosclerotic disease in patients with diabetes |
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| المؤلفون: | Ardwan Dakhel, Moncef Zarrouk, Jan Ekelund, Stefan Acosta, Peter Nilsson, Mervete Miftaraj, Björn Eliasson, Ann-Marie Svensson, Anders Gottsäter |
| المصدر: | Therapeutic Advances in Endocrinology and Metabolism, Vol 11 (2020) |
| بيانات النشر: | SAGE Publishing, 2020. |
| سنة النشر: | 2020 |
| المجموعة: | LCC:Diseases of the endocrine glands. Clinical endocrinology |
| مصطلحات موضوعية: | Diseases of the endocrine glands. Clinical endocrinology, RC648-665 |
| الوصف: | Background: Diabetes mellitus (DM) is an established risk factor for intermittent claudication (IC) and other manifestations of atherosclerotic peripheral arterial disease. Indications for surgery in infrainguinal IC are debated, and there are conflicting reports regarding its outcomes in patients with DM. Aims of this study were to compare both short- and long-term effects on total- and cardiovascular (CV) mortality, major adverse cardiovascular events (MACEs), acute myocardial infarction (AMI), stroke, and major amputation following infrainguinal endovascular surgery for IC in patients with and without DM. We also evaluated potential relationships between diabetic control and outcomes in patients with DM. Methods: Nationwide observational cohort study of patients registered in the Swedish Vascular Registry and the Swedish National Diabetes Registry. Propensity score adjusted comparison of total and CV mortality, MACE, AMI, stroke, and major amputation after elective infrainguinal endovascular surgery for IC in 626 patients with and 1112 without DM at 30 postoperative days and after median 5.2 [interquartile range (IQR) 4.2–6.3] years of follow-up for patients with DM, and 5.4 (IQR 4.3–6.5) years for those without. Results: In propensity score adjusted Cox regression after 30 postoperative days, there were no differences between groups in morbidity or mortality. At last follow-up, patients with DM showed higher rates of MACE [hazard ratio (HR) 1.26, confidence interval (CI) 1.07–1.48; p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2042-0196 20420188 |
| العلاقة: | https://doaj.org/toc/2042-0196Test |
| DOI: | 10.1177/2042018820960294 |
| الوصول الحر: | https://doaj.org/article/5484dd1087ac4549a892832683fdaa07Test |
| رقم الانضمام: | edsdoj.5484dd1087ac4549a892832683fdaa07 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20420196 20420188 |
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| DOI: | 10.1177/2042018820960294 |