دورية أكاديمية

Distribution of Airborne Influenza Virus and Respiratory Syncytial Virus in an Urgent Care Medical Clinic.

التفاصيل البيبلوغرافية
العنوان: Distribution of Airborne Influenza Virus and Respiratory Syncytial Virus in an Urgent Care Medical Clinic.
المؤلفون: Lindsley, William G., Blachere, Francoise M., Davis, Kristina A., Pearce, Terri A., Fisher, Melanie A., Khakoo, Rashida, Davis, Stephen M., Rogers, Mark E., Thewlis, Robert E., Posada, Jose A., Redrow, John B., Celik, Ismail B., Chen, Bean T., Beezhold, Donald H.
المصدر: Clinical Infectious Diseases; 3/1/2010, Vol. 50 Issue 5, p693-698, 6p, 1 Chart, 4 Graphs
مصطلحات موضوعية: AIRBORNE infection, INFLUENZA viruses, RESPIRATORY syncytial virus, INFECTIOUS disease transmission, AEROSOLS, POLYMERASE chain reaction, HEALTH facilities, QUANTITATIVE research
مستخلص: Background. Considerable controversy exists with regard to whether influenza virus and respiratory syncytial virus (RSV) are spread by the inhalation of infectious airborne particles and about the importance of this route, compared with droplet or contact transmission. Methods. Airborne particles were collected in an urgent care clinic with use of stationary and personal aerosol samplers. The amounts of airborne influenza A, influenza B, and RSV RNA were determined using real-time quantitative polymerase chain reaction. Health care workers and patients participating in the study were tested for influenza. Results. Seventeen percent of the stationary samplers contained influenza A RNA, 1% contained influenza B RNA, and 32% contained RSV RNA. Nineteen percent of the personal samplers contained influenza A RNA, none contained influenza B RNA, and 38% contained RSV RNA. The number of samplers containing influenza RNA correlated well with the number and location of patients with influenza (r = 0.77). Forty-two percent of the influenza A RNA was in particles ⩽4.1 μm in aerodynamic diameter, and 9% of the RSV RNA was in particles ⩽4.1 μm. Conclusions. Airborne particles containing influenza and RSV RNA were detected throughout a health care facility. The particles were small enough to remain airborne for an extended time and to be inhaled deeply into the respiratory tract. These results support the possibility that influenza and RSV can be transmitted by the airborne route and suggest that further investigation of the potential of these particles to transmit infection is warranted. [ABSTRACT FROM AUTHOR]
Copyright of Clinical Infectious Diseases is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
قاعدة البيانات: Complementary Index