Two-year longitudinal monitoring of amnestic mild cognitive impairment patients with prodromal Alzheimer's disease using topographical biomarkers derived from functional magnetic resonance imaging and electroencephalographic activity
| العنوان: | Two-year longitudinal monitoring of amnestic mild cognitive impairment patients with prodromal Alzheimer's disease using topographical biomarkers derived from functional magnetic resonance imaging and electroencephalographic activity |
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| المؤلفون: | Jill C. Richardson, Flavio Nobili, Libera Cavaliere, Moira Marizzoni, Claudio Babiloni, Gianluigi Forloni, Giovanni B. Frisoniand, Mira Didic, Régis Bordet, Ludovico Minati, Jorge Jovicich, Susanna Lopez, Marco Salvatore, Jens Wiltfang, David Bartrés Faz, Claudio Del Percio, Camillo Marra, Giuseppe Noce, Andrea Soricelli, Diego Albani, Clarissa Ferrari, Tilman Hensch, Lucilla Parnetti, José Luis Molinuevo, Olivier Blin, Pierre Payoux, Cinzia Costa, Peter Schönknecht, Roberta Lizio, Pieter Jelle Visser, Magda Tsolaki, Lucia Farotti, Paolo Maria Rossini, Samantha Galluzzi, Ute Fiedler, Daniele Orlandi, Davide V. Moretti |
| المساهمون: | University of Trento [Trento], Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome] (UNIROMA), Centro San Giovanni di Dio, Fatebenefratelli, Brescia (IRCCS), Università degli Studi di Brescia = University of Brescia (UniBs), IRCCS SDN Napoli, IRCCS Istituto Nazionale dei Tumori [Milano], Institut de Neurosciences des Systèmes (INS), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut National de la Santé et de la Recherche Médicale (INSERM), Universität Duisburg-Essen = University of Duisburg-Essen [Essen], Universität Leipzig, Pasqual Maragall Foundation, Universitat de Barcelona (UB), Università degli studi di Genova = University of Genoa (UniGe), Università degli Studi di Perugia = University of Perugia (UNIPG), Toulouse Neuro Imaging Center (ToNIC), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Toulouse Mind & Brain Institut (TMBI), Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT), Istituto Neurologico Mediterraneo (NEUROMED I.R.C.C.S.), Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome] (UNIROMA)-University of Naples Federico II = Università degli studi di Napoli Federico II, Aristotle University of Thessaloniki, VU University Medical Center [Amsterdam], GlaxoSmithKline, Glaxo Smith Kline, Université de Lille, Institut de Neurosciences de la Timone (INT), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Université de Genève = University of Geneva (UNIGE), Universität Duisburg-Essen [Essen], Universität Leipzig [Leipzig], Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Toulouse Mind & Brain Institut (TMBI), Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées, University of Duisburg-Essen, Otten, Lisa, Neurology, Amsterdam Neuroscience - Neurodegeneration |
| المصدر: | Journal of Alzheimer's Disease Journal of Alzheimer's Disease, 2019, 69 (1), pp.15-35. ⟨10.3233/JAD-180158⟩ Jovicich, J, Babiloni, C, Ferrari, C, Marizzoni, M, Moretti, D V, Del Percio, C, Lizio, R, Lopez, S, Galluzzi, S, Albani, D, Cavaliere, L, Minati, L, Didic, M, Fiedler, U, Forloni, G, Hensch, T, Molinuevo, J L, Bartrés Faz, D, Nobili, F, Orlandi, D, Parnetti, L, Farotti, L, Costa, C, Payoux, P, Rossini, P M, Marra, C, Schönknecht, P, Soricelli, A, Noce, G, Salvatore, M, Tsolaki, M, Visser, P J, Richardson, J C, Wiltfang, J, Bordet, R, Blin, O & Frisoniand, G B 2019, ' Two-year longitudinal monitoring of amnestic mild cognitive impairment patients with prodromal Alzheimer's disease using topographical biomarkers derived from functional magnetic resonance imaging and electroencephalographic activity ', Journal of Alzheimer's Disease, vol. 69, no. 1, pp. 15-35 . https://doi.org/10.3233/JAD-180158Test Journal of Alzheimer's Disease, 69(1), 15-35. IOS Press |
| بيانات النشر: | HAL CCSD, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | 0301 basic medicine, Male, pharma cog project, Medizin, Prodromal Alzheimer's Disease, Electroencephalography, Audiology, Neuropsychological Tests, Amnesic Mild Cognitive Impairment (aMCI), 0302 clinical medicine, PharmaCog project, Alpha rhythms, prodromal alzheimer’s disease, Longitudinal Studies, Default mode network, ComputingMilieux_MISCELLANEOUS, medicine.diagnostic_test, General Neuroscience, Brain, clinical trial, General Medicine, Middle Aged, Magnetic Resonance Imaging, Clinical Trial, Psychiatry and Mental health, Clinical Psychology, Settore MED/26 - NEUROLOGIA, Resting State, alpha rhythms, amnesic mild cognitive impairment, biomarkers, electroencephalography, functional magnetic resonance imaging, oddball event-related potentials, resting state, Functional Magnetic Resonance Imaging (fMRI), Disease Progression, Evoked Potentials, Auditory, Female, prodromal Alzheimer’s disease, medicine.medical_specialty, Posterior parietal cortex, 03 medical and health sciences, Alzheimer Disease, medicine, Dementia, Humans, Cognitive Dysfunction, Electroencephalography (EEG), Aged, prodromal Alzheimer's disease, Resting state fMRI, business.industry, [SCCO.NEUR]Cognitive science/Neuroscience, [SCCO.NEUR] Cognitive science/Neuroscience, medicine.disease, Cortex (botany), 030104 developmental biology, Posterior cingulate, Amnesia, Geriatrics and Gerontology, Functional magnetic resonance imaging, business, 030217 neurology & neurosurgery, Oddball Event-Related Potentials (ERPs), Biomarkers |
| الوصف: | Auditory "oddball" event-related potentials (aoERPs), resting state functional magnetic resonance imaging (rsfMRI) connectivity, and electroencephalographic (rsEEG) rhythms were tested as longitudinal functional biomarkers of prodromal Alzheimer's disease (AD). Data were collected at baseline and four follow-ups at 6, 12, 18, and 24 months in amnesic mild cognitive impairment (aMCI) patients classified in two groups: "positive" (i.e., "prodromal AD" n=81) or "negative" (n=63) based on a diagnostic marker of AD derived from cerebrospinal samples (Aβ 42 /P-tau ratio). A linear mixed model design was used to test functional biomarkers for Group, Time, and Group×Time effects adjusted by nuisance covariates (only data until conversion to dementia was used). Functional biomarkers that showed significant Group effects ("positive" versus "negative", p |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1387-2877 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37dbc7517269f82b3d05b09cfb6b1026Test https://hal.science/hal-03609814Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....37dbc7517269f82b3d05b09cfb6b1026 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13872877 |
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