Advances and controversies in the management of soft tissue sarcomas
| العنوان: | Advances and controversies in the management of soft tissue sarcomas |
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| المؤلفون: | Paolo G. Casali, Jean-Yves Blay, George D. Demetri |
| المصدر: | Future Oncology. 13:3-11 |
| بيانات النشر: | Future Medicine Ltd, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Cancer Research, medicine.medical_specialty, histology-driven therapy, Settore MED/06 - Oncologia Medica, Antineoplastic Agents, 03 medical and health sciences, 0302 clinical medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Doxorubicin, Molecular Targeted Therapy, 030212 general & internal medicine, Intensive care medicine, Trabectedin, Neoplasm Staging, sarcoma reference centers, Clinical Trials as Topic, business.industry, Soft tissue sarcoma, Disease Management, Soft tissue, Sarcoma, General Medicine, medicine.disease, Surgery, soft tissue sarcoma, trabectedin, Treatment Outcome, Oncology, 030220 oncology & carcinogenesis, business, medicine.drug |
| الوصف: | Intensive clinical research in the sarcoma field has provided insight into the histopathological diversity of soft tissue sarcomas (STS) and led to the introduction of many new agents that promise to play an important role in the management of patients with STS. While an increasing body of scientific data has advanced our knowledge of this complex family of mesenchymal diseases, several controversies remain to be resolved: Is doxorubicin-based therapy still the definitive standard first-line treatment for all patients with unresectable and/or metastatic STS of all subtypes? Is histology-driven therapy beyond gastrointestinal stromal tumors a reality or are we pursuing an unachievable objective? Are we making practical headway in the establishment of sarcoma reference centers? Is it clearly established which is the best parameter to evaluate the efficacy of a new agent in STS? |
| تدمد: | 1744-8301 1479-6694 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2dd22a53b82922fc27347ea9b3e8757Test https://doi.org/10.2217/fon-2016-0498Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....c2dd22a53b82922fc27347ea9b3e8757 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17448301 14796694 |
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