Risk factors of postoperative pulmonary complications in patients with asthma and COPD
| العنوان: | Risk factors of postoperative pulmonary complications in patients with asthma and COPD |
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| المؤلفون: | Satoko Fujii, Jun Araya, Kenji Kobayashi, Masahiro Yoshida, Takeo Ishikawa, Hirofumi Utsumi, Katsutoshi Nakayama, Hiromichi Hara, Nayuta Saito, Yusuke Kurita, Mitsuo Hashimoto, Shunsuke Minagawa, Haruhiko Yanagisawa, Yumi Kaneko, Takanori Numata, Kazuyoshi Kuwano, Hiroshi Wakui, Yoko Yumino, Saburo Ito |
| المصدر: | BMC Pulmonary Medicine, Vol 18, Iss 1, Pp 1-8 (2018) BMC Pulmonary Medicine |
| بيانات النشر: | BMC, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Adult, Male, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Neutrophils, medicine.medical_treatment, Operative Time, Severity of Illness Index, Leukocyte Count, Pulmonary Disease, Chronic Obstructive, Young Adult, 03 medical and health sciences, Postoperative Complications, 0302 clinical medicine, Internal medicine, Abdomen, medicine, Humans, COPD, 030212 general & internal medicine, Risk factor, Aged, Retrospective Studies, Asthma, Aged, 80 and over, lcsh:RC705-779, business.industry, Smoking, Age Factors, Perioperative, Odds ratio, lcsh:Diseases of the respiratory system, Middle Aged, Eosinophil, Cataract surgery, medicine.disease, Confidence interval, respiratory tract diseases, Eosinophils, medicine.anatomical_structure, 030228 respiratory system, Risk factors, Female, business, Postoperative pulmonary complication, Research Article |
| الوصف: | Background Postoperative pulmonary complications (PPC) in patients with pulmonary diseases remain to be resolved clinical issue. However, most evidence regarding PPC has been established more than 10 years ago. Therefore, it is necessary to evaluate perioperative management using new inhalant drugs in patients with obstructive pulmonary diseases. Methods April 2014 through March 2015, 346 adult patients with pulmonary diseases (257 asthma, 89 chronic obstructive pulmonary disease (COPD)) underwent non-pulmonary surgery except cataract surgery in our university hospital. To analyze the risk factors for PPC, we retrospectively evaluated physiological backgrounds, surgical factors and perioperative specific treatment for asthma and COPD. Results Finally, 29 patients with pulmonary diseases (22 asthma, 7 COPD) had PPC. In patients with asthma, smoking index (≥ 20 pack-years), peripheral blood eosinophil count (≥ 200/mm3) and severity (Global INitiative for Asthma(GINA) STEP ≥ 3) were significantly associated with PPC in the multivariate logistic regression analysis [odds ratio (95% confidence interval) = 5.4(1.4–20.8), 0.31 (0.11–0.84) and 3.2 (1.04–9.9), respectively]. In patients with COPD, age, introducing treatment for COPD, upper abdominal surgery and operation time (≥ 5 h) were significantly associated with PPC [1.18 (1.00–1.40), 0.09 (0.01–0.81), 21.2 (1.3–349) and 9.5 (1.2–77.4), respectively]. Conclusions History of smoking or severe asthma is a risk factor of PPC in patients with asthma, and age, upper abdominal surgery, or long operation time is a risk factor of PPC in patients with COPD. Adequate inhaled corticosteroids treatment in patients with eosinophilic asthma and introducing treatment for COPD in patients with COPD could reduce PPCs. |
| اللغة: | English |
| تدمد: | 1471-2466 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d37d94975b8c609a6cb496ceb4f5d11dTest http://link.springer.com/article/10.1186/s12890-017-0570-8Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....d37d94975b8c609a6cb496ceb4f5d11d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14712466 |
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