CLONING AND SEQUENCE ANALYSIS OF MOUSE cDNAs ENCODING PREPROTACHYKININ A AND B
| العنوان: | CLONING AND SEQUENCE ANALYSIS OF MOUSE cDNAs ENCODING PREPROTACHYKININ A AND B |
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| المؤلفون: | Kazuhisa Nakayama, Masahiro Hosaka, Kazuo Murakami, Eisuke Munekata, Koichiro Kako |
| المصدر: | Biomedical Research. 14:253-259 |
| بيانات النشر: | Biomedical Research Press, 1993. |
| سنة النشر: | 1993 |
| مصطلحات موضوعية: | Sequence analysis, Nucleic acid sequence, Substance P, General Medicine, Biology, Molecular biology, General Biochemistry, Genetics and Molecular Biology, chemistry.chemical_compound, Exon, Biochemistry, chemistry, Complementary DNA, Coding region, heterocyclic compounds, Neurokinin A, Neurokinin B |
| الوصف: | We describe here the isolation and characterization of cDNAs from mouse brain coding for the precursor of substance P and neurokinin A, preprotachykinin A (PPT-A), and for the precursor of neurokinin B, preprotachykinin B (PPT-B). Two types of mouse PPT-A cDNA encoding β-PPT-A and γ-PPT-A were obtained. The latter lacked the coding region corresponding to the exon 4 of the PPT-A gene, as is observed in other species. Mouse β-PPT-A deduced from the cDNA sequence consisted of 130 amino acids, and showed extensive homology to rat, human, and bovine β-PPT-As, with 99%, 95%, 92% amino acid identities, respectively. The substance P and neurokinin A sequences were the same among these species |
| تدمد: | 1880-313X 0388-6107 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::82adf36616de660f666979f6503091feTest https://doi.org/10.2220/biomedres.14.253Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi...........82adf36616de660f666979f6503091fe |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1880313X 03886107 |
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