دورية أكاديمية

Long-term histological outcomes of injected autologous fat into human vocal folds after secondary laryngectomy

التفاصيل البيبلوغرافية
العنوان: Long-term histological outcomes of injected autologous fat into human vocal folds after secondary laryngectomy
المؤلفون: Sasai, Hisanori, Watanabe, Yusuke, Muta, Hiroshi, Yoshida, Junichi, Hayashi, Ibuki, Ogawa, Makoto, Kubo, Takeshi
المصدر: Otolaryngology-Head & Neck Surgery; May2005, Vol. 132 Issue 5, p685-688, 4p
مستخلص: Objective: To histologically evaluate the long-term outcomes of autologous fat grafts after injection laryngoplasty in the human larynx. Study design and setting: We injected liposuctioned fat for vocal fold augmentation in patients with vocal fold paralysis. We suctioned autologous fat from the low abdomen with an 18-G disposable needle and a 20-mL disposable syringe under negative pressure. This is different from the conventional liposuction technique and avoids the use of special equipment. In this article, we report the histological evaluation of 2 patients (patient 1: 12 months, patient 2: 41 months) who required total laryngectomy after autologous fat injection into the vocal folds. Results: Histological examination revealed normal-appearing viable adipocytes with minimal inflammatory response in both patients. Conclusions: Our liposuctioned autologous fat injection histologically offered long-term improvement in patients with impaired glottal closure from vocal fold paralysis. [Copyright &y& Elsevier]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:01945998
DOI:10.1016/j.otohns.2005.01.005