المؤلفون: Wilcox, N., Wahlström, C., Kvist, A., Simard, J.

المصدر: Nature Genetics. 55(9):1435-1439

مصطلحات موضوعية: Exome, Exome Sequencing, Female, Humans, Mutation, Missense, Neoplasms, ATM protein, ATR protein, BRCA1 associated ring domain protein 1, BRCA1 protein, BRCA2 protein, checkpoint kinase 2, partner and localizer of BRCA2, adult, Article, breast cancer, cancer risk, cancer susceptibility, controlled study, female, gene frequency, gene identification, genetic association, genetic linkage, genetic susceptibility, genetic variability, human, lztr1 gene, major clinical study, map3k1 gene, missense mutation, oncogene, whole exome sequencing, exome, genetics, meta analysis, neoplasm, Medicin och hälsovetenskap, Medicinska och farmaceutiska grundvetenskaper, Medicinsk genetik, Medical and Health Sciences, Basic Medicine, Medical Genetics, Klinisk medicin, Cancer och onkologi, Clinical Medicine, Cancer and Oncology

الوصول الحر: https://lup.lub.lu.se/record/69c36c9b-10ee-4f40-8800-b6aec24ba791Test
http://dx.doi.org/10.1038/s41588-023-01466-zTest

المؤلفون: Paul Brennan, Younghun Han, Vladimir Janout, Eleonora Fabianova, Mark Lathrop, Zhaoming Wang, Inger Njølstad, James McKay, Dana Mates, Jolanta Lissowska, Frank Skorpen, Chu Chen, Neonilia Szeszenia-Dabrowska, Françoise Clavel-Chapelon, Antonio Agudo, Mattias Johansson, David C. Christiani, Kay-Tee Khaw, Yongyue Wei, Thorunn Rafnar, Gary E. Goodman, Mikael Johansson, Daniel Chubb, Xuchen Zong, Simone Benhamou, Vladimir Bencko, Manon Delahaye-Sourdeix, Lars J. Vatten, Elio Riboli, Peter Rudnai, Maria Teresa Landi, Susan M. Gapstur, Yuanqing Ye, Nilanjan Chatterjee, Amy Lloyd, Margaret R. Spitz, Paolo Vineis, H. Bas Bueno-de-Mesquita, William Wheeler, Ghislaine Scelo, Jan Lubinski, Stephen J. Chanock, Valerie Gaborieau, Victoria L. Stevens, Marc Henrion, Kari Stefansson, David Zaridze, Peter Broderick, Jian Gu, Mari Nelis, Elisabete Weiderpass, Albert Rosenberger, Maiken Elvestad Gabrielsen, Dimitrios Trichopoulos, Kristjan Välk, Florence LeCalvez-Kelm, Tõnu Vooder, Ben Kinnersley, Richard S. Houlston, Xifeng Wu, Anne Tjønneland, Yufei Wang, Hans E. Krokan, Demetrius Albanes, Patrick Sulem, Neil E. Caporaso, Geoffrey Liu, Marina Laplana, Christopher I. Amos, T. Eisen, Li Su, Lenka Foretova, Gudmar Thorleifsson, Rayjean J. Hung, Andres Metspalu, Maxime Vallée, Athena Matakidou, Hendrik Dienemann, Rudolf Kaaks, Marcin Lener, Angela Risch, Maria Timofeeva, Wei V. Chen

المصدر: Nature genetics
Recercat. Dipósit de la Recerca de Catalunya
instname
Repositorio Abierto de la UdL
Universitad de Lleida

مصطلحات موضوعية: Lung Neoplasms, Genome-wide association study, Biology, Adenocarcinoma, Bioinformatics, Polymorphism, Single Nucleotide, Article, 03 medical and health sciences, 0302 clinical medicine, Meta-Analysis as Topic, Risk Factors, Genetics, medicine, Humans, Genetic Predisposition to Disease, 1000 Genomes Project, Lung cancer, CHEK2, 030304 developmental biology, BRCA2 Protein, 0303 health sciences, 9. Industry and infrastructure, Case-control study, Odds ratio, medicine.disease, Prognosis, 3. Good health, Checkpoint Kinase 2, 030220 oncology & carcinogenesis, Case-Control Studies, Carcinoma, Squamous Cell, Imputation (genetics), Genome-Wide Association Study

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::556dbbc3bffeeb03ebad40c72f6fd62aTest
https://pubmed.ncbi.nlm.nih.gov/28358128Test

المؤلفون: Kevin D. Brown, Jennifer L. Mannino, Ravindra Kamath, Qimin Zhan, Dillon I. Beardsley, Abhilasha V. Rathi, R. Baskaran

المصدر: Nature genetics. 33(1)

مصطلحات موضوعية: DNA Replication, DNA Repair, Mismatch repair complex, DNA damage, Base Pair Mismatch, Cell Cycle Proteins, Ataxia Telangiectasia Mutated Proteins, Biology, Protein Serine-Threonine Kinases, Models, Biological, Radiation Tolerance, S Phase, Proto-Oncogene Proteins, Radiation, Ionizing, Genetics, Tumor Cells, Cultured, Humans, cdc25 Phosphatases, Phosphorylation, Checkpoint Kinase 2, Adaptor Proteins, Signal Transducing, Tumor Suppressor Proteins, Nuclear Proteins, G2-M DNA damage checkpoint, Cell biology, Nibrin, Neoplasm Proteins, DNA-Binding Proteins, Enzyme Activation, MutS Homolog 2 Protein, Biochemistry, MSH2, DNA mismatch repair, Carrier Proteins, MutL Protein Homolog 1, Protein Kinases, Gene Deletion

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6536603e64731137169531b1d208293cTest
https://pubmed.ncbi.nlm.nih.gov/15118672Test

المؤلفون: Jiri Bartek, John H.J. Petrini, Bret R. Williams, Jiri Lukas, Jacob Falck

المصدر: Nature genetics. 30(3)

مصطلحات موضوعية: DNA damage, DNA polymerase, Cell Cycle Proteins, Ataxia Telangiectasia Mutated Proteins, Protein Serine-Threonine Kinases, Cell Line, S Phase, chemistry.chemical_compound, Radiation, Ionizing, Genetics, CDC2-CDC28 Kinases, Humans, cdc25 Phosphatases, Checkpoint Kinase 2, DNA synthesis, biology, Tumor Suppressor Proteins, Cyclin-Dependent Kinase 2, DNA replication, Nuclear Proteins, G2-M DNA damage checkpoint, Cell cycle, Cyclin-Dependent Kinases, Cell biology, DNA-Binding Proteins, enzymes and coenzymes (carbohydrates), Biochemistry, chemistry, biology.protein, biological phenomena, cell phenomena, and immunity, Protein Kinases, DNA, DNA Damage

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4579bfbc26da86019e5567c4115b4b41Test
https://pubmed.ncbi.nlm.nih.gov/11850621Test

المؤلفون: Vanessa Brevet, Vera Schramke, Maria Pia Longhese, Yves Corda, Eric Gilson, Vera Paciotti, Tamara Smokvina, Vincent Géli

المصدر: Nature genetics. 21(2)

مصطلحات موضوعية: Saccharomyces cerevisiae Proteins, DNA Repair, DNA repair, DNA damage, Chromosomal Proteins, Non-Histone, Cell Cycle Proteins, Saccharomyces cerevisiae, Biology, Protein Serine-Threonine Kinases, medicine.disease_cause, Fungal Proteins, chemistry.chemical_compound, Gene Expression Regulation, Fungal, Genetics, medicine, Epigenetics, Telomere-binding protein, Mutation, Cell Cycle, Proteins, Cell cycle, Telomere, Molecular biology, Checkpoint Kinase 2, chemistry, Protein Kinases, DNA, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f2b1212bb7f9467ff7e95b1d7331faaTest
https://pubmed.ncbi.nlm.nih.gov/9988261Test