دورية أكاديمية
The synthesis, characterization, antioxidant and antimicrobial activity of some novel amides of the esters of substituted 1,4-dihydropyridines
| العنوان: | The synthesis, characterization, antioxidant and antimicrobial activity of some novel amides of the esters of substituted 1,4-dihydropyridines |
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| المؤلفون: | Nikolić Jasmina B., Prlainović Nevena Ž., Šekularac Gavrilo M., Matović Luka R., Lazić Anita M., Drmanić Saša Ž. |
| المصدر: | Journal of the Serbian Chemical Society, Vol 89, Iss 2, Pp 141-150 (2024) |
| بيانات النشر: | Serbian Chemical Society, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Chemistry |
| مصطلحات موضوعية: | biologically active compounds, dpph analysis, abts analysis, broth microdilution method, Chemistry, QD1-999 |
| الوصف: | The esters of substituted 1,4-dihydropyirdines (1,4-DHP) are formed in the reaction of an appropriate aldehyde and ethyl acetoacetate in the presence of concentrated water solution of ammonia. The esters form the amides by the reaction with primary amines. The series of the amides has been synthesized with the aim to analyze their chemical characteristics, antioxidant and antimicrobial activity. The amine used in this research is 2-aminothiazole. The antioxidant activity is analysed by 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-Azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) methods and the antimicrobial activity screening was performed by broth microdilution method, using different microbial strains. The characterization of the obtained amides was done by melting points, FTIR, NMR and elemental analysis. The possibilities for further research was suggested, which could lead to the application of selected compounds. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0352-5139 1820-7421 |
| العلاقة: | https://doaj.org/toc/0352-5139Test; https://doaj.org/toc/1820-7421Test |
| DOI: | 10.2298/JSC231023098N |
| الوصول الحر: | https://doaj.org/article/3f5e480c8a91402da426715c40f0c4c1Test |
| رقم الانضمام: | edsdoj.3f5e480c8a91402da426715c40f0c4c1 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 03525139 18207421 |
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| DOI: | 10.2298/JSC231023098N |