De Novo Development of Distal Jejunal and Duodenal Adenomas After 41 Months of Teduglutide Treatment in a Patient With Short‐Bowel Syndrome: A Case Report
| العنوان: | De Novo Development of Distal Jejunal and Duodenal Adenomas After 41 Months of Teduglutide Treatment in a Patient With Short‐Bowel Syndrome: A Case Report |
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| المؤلفون: | Sebastian Maasberg, Ulrich-Frank Pape, Sefer Elezkurtaj, S Pevny, Christian Jürgensen, Elisabeth Blüthner, Christoph Jochum, Anja Rieger, Frank Tacke |
| المصدر: | Journal of Parenteral and Enteral Nutrition. 45:652-656 |
| بيانات النشر: | Wiley, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | medicine.medical_specialty, 030309 nutrition & dietetics, Medicine (miscellaneous), Teduglutide, Gastroenterology, Jejunum, 03 medical and health sciences, Duodenal Adenoma, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, medicine, 0303 health sciences, Nutrition and Dietetics, medicine.diagnostic_test, business.industry, digestive, oral, and skin physiology, Short bowel syndrome, medicine.disease, digestive system diseases, Chronic intestinal failure, Endoscopy, medicine.anatomical_structure, Parenteral nutrition, chemistry, Duodenum, 030211 gastroenterology & hepatology, business |
| الوصف: | The glucagon-like peptide-2 (GLP-2) analogue teduglutide is a medical treatment option for patients with short-bowel syndrome-associated chronic intestinal failure. Because studies in mice have shown that GLP-2 analogues may promote the growth of colonic neoplasms, surveillance colonoscopies before and during teduglutide therapy were recommended. The occurrence of small-intestinal neoplasms has not been reported so far, except for a recent report about de novo development of hamartomatous duodenal polyps. We report a case of de novo development of small-intestinal premalignant adenomatous polyps in both bulbar duodenum and distal jejunum in a patient treated with teduglutide for 41 months. Therefore, additional endoscopic surveillance of the upper gastrointestinal tract may be advised during teduglutide therapy for early detection and removal of potential small-bowel adenomas. |
| تدمد: | 1941-2444 0148-6071 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::97cb478a2eae94ac714a79929deec8bdTest https://doi.org/10.1002/jpen.1982Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi...........97cb478a2eae94ac714a79929deec8bd |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19412444 01486071 |
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