التفاصيل البيبلوغرافية
| العنوان: |
Effects of Mad Honey on Some Biochemical Parameters in Rats. |
| المؤلفون: |
Sahin, Huseyin, Yildiz, Oktay, Kolayli, Sevgi |
| المصدر: |
Journal of Evidence-Based Complementary & Alternative Medicine; Oct2016, Vol. 21 Issue 4, p255-259, 5p |
| مصطلحات موضوعية: |
ALKALINE phosphatase, ANIMAL experimentation, ASPARTATE aminotransferase, BIOMARKERS, CREATINE kinase, ENZYMES, GAS chromatography, HONEY, ISOENZYMES, LACTATE dehydrogenase, MASS spectrometry, RATS, SERUM, ALANINE aminotransferase, DATA analysis software |
| مصطلحات جغرافية: |
TURKEY |
| مستخلص: |
The aims of this study were to determine grayanotoxin (GTX-III) toxin level in mad honey using liquid chromatography-tandem mass spectrometry and examine the dynamic changes of certain biochemical parameters in blood serum of rats that consumed mad honey. For the experimental animal study, 20 Sprague-Dawley female rats were divided into 5 groups of 4 rats each, with one group being the control group (Group I) and the others being the experimental groups (Groups 2-5). Groups 2, 3,4, and 5 were, respectively, given mad honey extract at doses of 0.3, 0.6, 1.2, and 2.4 mg/g body weight/day via oral gavage for 8 days. According to results, the quantity of GTX-III found in the honey sample as 39.949 ± 0.020 μg GTX-lll/g honey, and the biochemical analysis of the tested parameters (aspartate aminotransferase, alanine aminotransferase, lactate dehydrogenase, alkaline phosphatase, creatine kinase, and creatine kinase muscle and brain) showed a significant elevation with increasing concentration of honey. In conclusion, the use of increasing concentrations of Rhododendron honey was seen as a source of enzymatic symptoms. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
