دورية أكاديمية

Exploiting sample variability to enhance multivariate analysis of microarray data.

التفاصيل البيبلوغرافية
العنوان: Exploiting sample variability to enhance multivariate analysis of microarray data.
المؤلفون: Möller-Levet, Carla S.1,2 cmoller@picr.man.ac.uk, West, Catharine M.2, Miller, Crispin J.1
المصدر: Bioinformatics. Oct2007, Vol. 23 Issue 20, p2733-2740. 8p. 1 Diagram, 1 Chart, 6 Graphs.
مصطلحات موضوعية: *DNA microarrays, *GENE expression, *CANCER diagnosis, *CANCER genetics, *GENETIC regulation
مستخلص: Motivation: Biological and technical variability is intrinsic in any microarray experiment. While most approaches aim to account for this variability, they do not actively exploit it. Here, we consider a novel approach that uses the variability between arrays to provide an extra source of information that can enhance gene expression analyses. [ABSTRACT FROM PUBLISHER]
قاعدة البيانات: Academic Search Index
الوصف
تدمد:13674803
DOI:10.1093/bioinformatics/btm441