التفاصيل البيبلوغرافية
| العنوان: |
Expression, purification, and crystal structure of N-terminal domains of human ubiquitin-activating enzyme (El). |
| المؤلفون: |
Shu-Tao Xie |
| المصدر: |
Bioscience, Biotechnology & Biochemistry; Sep2014, Vol. 78 Issue 9, p1542-1549, 8p |
| مصطلحات موضوعية: |
UBIQUITIN-protein ligase structure, UBIQUITIN, MOLECULAR structure, ADENYLATION (Biochemistry), CHEMICAL synthesis, CRYSTAL structure, DNA structure |
| مستخلص: |
The article discusses aspects on the understanding the mechanisms of post-translational modification of protein by ubiquitin and ubiquitin-like molecules (UBLs) activation in humans. It states the significant of UBLs in several physiological processes including protein quality control, innate and adaptive immune response and DNA repair. It also emphasizes the various correlations of different UBLs in humans that is based on their domain architecture. |
| قاعدة البيانات: |
Supplemental Index |
