المؤلفون: Dreyfus, Julien, Taramasso, Maurizio, Kresoja, Karl-Patrik, Omran, Hazem, Iliadis, Christos, Russo, Giulio, Weber, Marcel, Nombela-Franco, Luis, Estevez Loureiro, Rodrigo, Hausleiter, Jörg, Latib, Azeem, Stolz, Lukas, Praz, Fabien, Windecker, Stephan, Zamorano, Jose Luis, von Bardeleben, Ralph Stephan, Tang, Gilbert H.L., Hahn, Rebecca, Lubos, Edith, Webb, John, Schofer, Joachim, Fam, Neil, Lauten, Alexander, Pedrazzini, Giovanni, Rodés-Cabau, Josep, Nejjari, Mohammed, Badano, Luigi, Alessandrini, Hannes, Himbert, Dominique, Sievert, Horst, Piayda, Kerstin, Donal, Erwan, Modine, Thomas, Nickenig, Georg, Pfister, Roman, Rudolph, Volker, Bernick, Jordan, Wells, George, Bax, Jeroen, Lurz, Philipp, Enriquez-Sarano, Maurice, Maisano, Francesco, Messika-Zeitoun, David, Ajmone-Marsan, Nina, Bartko, Philipp, Bazire, Baptiste, Benfari, Giovanni, Bohbot, Yohan, Carnero-Alcazar, Manuel, Chan, Vincent, Coisne, Augustin, Crestanello, Juan, de Bonis, Michele, Doguet, Fabien, Eggenspieler, Florian, Eixerés-Esteve, Andrea, Loureiro, Rodrigo Estevez, Eyharts, Damien, Flagiello, Michele, Galloo, Xavier, Gavazzoni, Mara, Habib, Gilbert, Heitzinger, Gregor, Iung, Bernard, Juarez-Casso, Fernando, Kresoja, Karl-Patrick, Lavie-Badie, Yoan, Le Tourneau, Thierry, Lim, Pascal, Mbaki, Yannick, Michelena, Hector, Muraru, Denisa, Nicol, Martin, Obadia, Jean-François, Radu, Costin, El Idrissi, Kenza Rahmouni, Riant, Elisabeth, Ruf, Tobias, Sala, Alessandra, Selton-Suty, Christine, Senage, Thomas, Tomasi, Jacques, Topilsky, Yan, Tribouilloy, Christophe, Viau, Florence

المساهمون: Centre cardiologique du Nord (CCN), Heart Center Hirslanden = HerzZentrum Hirslanden Zürich, Switzerland (HCL), Ruhr University Bochum = Ruhr-Universität Bochum (RUB), Instituto de Investigación Sanitaria del Hospital Clínico San Carlos Madrid, Spain (IdISSC), University-Hospital Munich-Großhadern München, Montefiore Medical Center Bronx, New York, Albert Einstein College of Medicine New York, Bern University Hospital Berne (Inselspital), Hospital Universitario Ramón y Cajal Madrid, Universidad de Alcalá - University of Alcalá (UAH), University Medical Center of the Johannes Gutenberg-University Mainz, Mount Sinai Health System, Columbia University Irving Medical Center (CUIMC), Medizinische Klinik und Poliklinik, Johannes Gutenberg - Universität Mainz = Johannes Gutenberg University (JGU), University of Cambridge UK (CAM), CHU Amiens-Picardie, Mécanismes physiopathologiques et conséquences des calcifications vasculaires - UR UPJV 7517 (MP3CV), Université de Picardie Jules Verne (UPJV)-CHU Amiens-Picardie, Centre Hospitalier Universitaire de Rennes CHU Rennes = Rennes University Hospital Ponchaillou, Laboratoire Traitement du Signal et de l'Image (LTSI), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)

المصدر: ISSN: 1936-8798.

مصطلحات موضوعية: survival, transcatheter intervention, tricuspid regurgitation, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system

الوصف: International audience ; Background: The safety profile of transcatheter tricuspid valve (TTV) repair techniques is well established, but residual tricuspid regurgitation (TR) remains a concern.Objectives: The authors sought to assess the impact of residual TR severity post-TTV repair on survival.Methods: We evaluated the survival rate at 2 years of 613 patients with severe isolated functional TR who underwent TTV repair in TRIGISTRY according to the severity of residual TR at discharge using a 3-grade (mild, moderate, and severe) or 4-grade scheme (mild, mild to moderate, moderate to severe, and severe).Results: Residual TR was none/mild in 33%, moderate in 52%, and severe in 15%. The 2-year adjusted survival rates significantly differed between the 3 groups (85%, 70%, and 44%, respectively; restricted mean survival time [RMST]: P = 0.0001). When the 319 patients with moderate residual TR were subdivided into mild to moderate (n = 201, 33%) and moderate to severe (n = 118, 19%), the adjusted survival rate was also significantly different between groups (85%, 80%, 55%, and 44%, respectively; RMST: P = 0.001). Survival was significantly lower in patients with moderate to severe residual TR compared to patients with mild to moderate residual TR (P = 0.006). No difference in survival rates was observed between patients with no/mild and mild to moderate residual TR (P = 0.67) or between patients with moderate to severe and severe residual TR (P = 0.96).Conclusions: The moderate residual TR group was heterogeneous and encompassed patients with markedly different clinical outcomes. Refining TR grade classification with a more granular 4-grade scheme improved outcome prediction. Our results highlight the importance of achieving a mild to moderate or lower residual TR grade during TTV repair, which could define a successful intervention.

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/38752971; hal-04595102; https://u-picardie.hal.science/hal-04595102Test; PUBMED: 38752971

الإتاحة: https://doi.org/10.1016/j.jcin.2024.04.023Test
https://u-picardie.hal.science/hal-04595102Test

المؤلفون: Dreyfus, Julien, Taramasso, Maurizio, Kresoja, Karl-Patrik, Omran, Hazem, Iliadis, Christos, Russo, Giulio, Weber, Marcel, Nombela-Franco, Luis, Estevez Loureiro, Rodrigo, Hausleiter, Jörg, Latib, Azeem, Stolz, Lukas, Praz, Fabien, Windecker, Stephan, Zamorano, Jose Luis, von Bardeleben, Ralph Stephan, Tang, Gilbert H.L., Hahn, Rebecca, Lubos, Edith, Webb, John, Schofer, Joachim, Fam, Neil, Lauten, Alexander, Pedrazzini, Giovanni, Rodés-Cabau, Josep, Nejjari, Mohammed, Badano, Luigi, Alessandrini, Hannes, Himbert, Dominique, Sievert, Horst, Piayda, Kerstin, Donal, Erwan, Modine, Thomas, Nickenig, Georg, Pfister, Roman, Rudolph, Volker, Bernick, Jordan, Wells, George, Bax, Jeroen, Lurz, Philipp, Enriquez-Sarano, Maurice, Maisano, Francesco, Messika-Zeitoun, David, Ajmone-Marsan, Nina, Bartko, Philipp, Bazire, Baptiste, Benfari, Giovanni, Bohbot, Yohan, Carnero-Alcazar, Manuel, Chan, Vincent, Coisne, Augustin, Crestanello, Juan, de Bonis, Michele, Doguet, Fabien, Eggenspieler, Florian, Eixerés-Esteve, Andrea, Loureiro, Rodrigo Estevez, Eyharts, Damien, Flagiello, Michele, Galloo, Xavier, Gavazzoni, Mara, Habib, Gilbert, Heitzinger, Gregor, Iung, Bernard, Juarez-Casso, Fernando, Kresoja, Karl-Patrick, Lavie-Badie, Yoan, Le Tourneau, Thierry, Lim, Pascal, Mbaki, Yannick, Michelena, Hector, Muraru, Denisa, Nicol, Martin, Obadia, Jean-François, Radu, Costin, El Idrissi, Kenza Rahmouni, Riant, Elisabeth, Ruf, Tobias, Sala, Alessandra, Selton-Suty, Christine, Senage, Thomas, Tomasi, Jacques, Topilsky, Yan, Tribouilloy, Christophe, Viau, Florence

المساهمون: Centre cardiologique du Nord (CCN), Heart Center Hirslanden = HerzZentrum Hirslanden Zürich, Switzerland (HCL), Ruhr University Bochum = Ruhr-Universität Bochum (RUB), Instituto de Investigación Sanitaria del Hospital Clínico San Carlos Madrid, Spain (IdISSC), University-Hospital Munich-Großhadern München, Montefiore Medical Center Bronx, New York, Albert Einstein College of Medicine New York, Bern University Hospital Berne (Inselspital), Hospital Universitario Ramón y Cajal Madrid, Universidad de Alcalá - University of Alcalá (UAH), University Medical Center of the Johannes Gutenberg-University Mainz, Mount Sinai Health System, Columbia University Irving Medical Center (CUIMC), Medizinische Klinik und Poliklinik, Johannes Gutenberg - Universität Mainz = Johannes Gutenberg University (JGU), University of Cambridge UK (CAM), CHU Amiens-Picardie, Mécanismes physiopathologiques et conséquences des calcifications vasculaires - UR UPJV 7517 (MP3CV), Université de Picardie Jules Verne (UPJV)-CHU Amiens-Picardie, Centre Hospitalier Universitaire de Rennes CHU Rennes = Rennes University Hospital Ponchaillou, Laboratoire Traitement du Signal et de l'Image (LTSI), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)

المصدر: ISSN: 1936-8798.

مصطلحات موضوعية: survival, transcatheter intervention, tricuspid regurgitation, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system

الوصف: International audience ; Background: The safety profile of transcatheter tricuspid valve (TTV) repair techniques is well established, but residual tricuspid regurgitation (TR) remains a concern.Objectives: The authors sought to assess the impact of residual TR severity post-TTV repair on survival.Methods: We evaluated the survival rate at 2 years of 613 patients with severe isolated functional TR who underwent TTV repair in TRIGISTRY according to the severity of residual TR at discharge using a 3-grade (mild, moderate, and severe) or 4-grade scheme (mild, mild to moderate, moderate to severe, and severe).Results: Residual TR was none/mild in 33%, moderate in 52%, and severe in 15%. The 2-year adjusted survival rates significantly differed between the 3 groups (85%, 70%, and 44%, respectively; restricted mean survival time [RMST]: P = 0.0001). When the 319 patients with moderate residual TR were subdivided into mild to moderate (n = 201, 33%) and moderate to severe (n = 118, 19%), the adjusted survival rate was also significantly different between groups (85%, 80%, 55%, and 44%, respectively; RMST: P = 0.001). Survival was significantly lower in patients with moderate to severe residual TR compared to patients with mild to moderate residual TR (P = 0.006). No difference in survival rates was observed between patients with no/mild and mild to moderate residual TR (P = 0.67) or between patients with moderate to severe and severe residual TR (P = 0.96).Conclusions: The moderate residual TR group was heterogeneous and encompassed patients with markedly different clinical outcomes. Refining TR grade classification with a more granular 4-grade scheme improved outcome prediction. Our results highlight the importance of achieving a mild to moderate or lower residual TR grade during TTV repair, which could define a successful intervention.

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/38752971; hal-04595102; https://u-picardie.hal.science/hal-04595102Test; PUBMED: 38752971

الإتاحة: https://doi.org/10.1016/j.jcin.2024.04.023Test
https://u-picardie.hal.science/hal-04595102Test