دورية أكاديمية
Genomic comparison of Salmonella typhimurium DT104 with non-DT104 strains
| العنوان: | Genomic comparison of Salmonella typhimurium DT104 with non-DT104 strains |
|---|---|
| المؤلفون: | Zhao, Er-Ying, Bao, Hong-Xia, Tang, Le, Zou, Qing-Hua, Liu, Wei-Qiao, Zhu, Da-Ling, Chin, Jessica, Dong, Ying-Ying, Li, Yong-Guo, Cao, Feng-Lin, Poppe, Cornelis, Sanderson, Kenneth E., Johnston, Randal N., Zhou, Daoguo, Liu, Gui-Rong, Liu, Shu-Lin |
| المساهمون: | Zou, QH (reprint author), Harbin Med Univ, Genom Res Ctr, State Prov Key Labs Biomed Pharmaceut China 1, 157 Baojian Rd, Harbin 150081, Peoples R China., Harbin Med Univ, Genom Res Ctr, State Prov Key Labs Biomed Pharmaceut China 1, Harbin 150081, Peoples R China., Harbin Med Univ, HMU UCFM Ctr Infect & Genom, Harbin 150081, Peoples R China., Peking Univ, Hlth Sci Ctr, Dept Microbiol, Beijing 100871, Peoples R China., Univ Calgary, Dept Microbiol, Calgary, AB, Canada., Univ Calgary, Dept Infect Dis, Calgary, AB, Canada., Harbin Med Univ, Fac Pharm, Dept Biopharmaceut, Harbin 150081, Peoples R China., Harbin Med Univ, Hosp 1, Genet Diag Lab, Harbin 150081, Peoples R China., Publ Hlth Agcy Canada, Lab Foodborne Zoonoses, Guelph, ON, Canada., Univ Calgary, Dept Biochem, Calgary, AB, Canada., Univ Calgary, Dept Mol Biol, Calgary, AB, Canada., Purdue Univ, Dept Biol Sci, W Lafayette, IN 47907 USA., Harbin Med Univ, Genom Res Ctr, State Prov Key Labs Biomed Pharmaceut China 1, 157 Baojian Rd, Harbin 150081, Peoples R China. |
| المصدر: | SCI |
| بيانات النشر: | molecular genetics and genomics |
| سنة النشر: | 2013 |
| المجموعة: | Peking University Institutional Repository (PKU IR) / 北京大学机构知识库 |
| مصطلحات موضوعية: | Salmonella typhimurium, DT104, Antimicrobial resistance, SGI-1, RIBOSOMAL-RNA, CLEAVAGE MAP, ENTERICA, RESISTANCE, SEQUENCE, TYPHI, IDENTIFICATION, GENES, ELECTROPHORESIS, CHOLERAESUIS |
| الوصف: | DT104 emerged as a new branch of Salmonella typhimurium with resistance to multiple antimicrobials. To reveal some general genomic features of DT104 for clues of evolutionary events possibly associated with the emergence of this relatively new type of this pathogen, we mapped 11 independent DT104 strains and compared them with non-DT104 S. typhimurium strains. We found that all 11 DT104 strains contained three insertions absent in non-DT104 strains, i.e., the previously reported ST104, ST104B and ST64B. However, SGI-1, a genomic island known to be responsible for DT104 multidrug resistance, was not present in all DT104 strains examined in this study: one DT104 strain did not contain SGI-1 but carried a 144 kb plasmid, suggesting possible evolutionary relationships between the two DNA elements in the development of antimicrobial resistance. ; Biochemistry & Molecular Biology ; Genetics & Heredity ; SCI(E) ; 1 ; ARTICLE ; 11 ; 549-557 ; 288 |
| نوع الوثيقة: | journal/newspaper |
| اللغة: | English |
| تدمد: | 1617-4615 1617-4623 |
| العلاقة: | MOLECULAR GENETICS AND GENOMICS.2013,288,(11),549-557.; 828952; http://hdl.handle.net/20.500.11897/224356Test; WOS:000326263900001 |
| DOI: | 10.1007/s00438-013-0762-8 |
| الإتاحة: | https://doi.org/20.500.11897/224356Test https://doi.org/10.1007/s00438-013-0762-8Test https://hdl.handle.net/20.500.11897/224356Test |
| رقم الانضمام: | edsbas.59D888E8 |
| قاعدة البيانات: | BASE |
| تدمد: | 16174615 16174623 |
|---|---|
| DOI: | 10.1007/s00438-013-0762-8 |