رسالة جامعية
Evaluation of absolute intracranial pressure by non-invasive auditory technology ; Evaluation de la pression intracrânienne absolue par une technologie non invasive auditive
| العنوان: | Evaluation of absolute intracranial pressure by non-invasive auditory technology ; Evaluation de la pression intracrânienne absolue par une technologie non invasive auditive |
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| المؤلفون: | Gonzalez Torrecilla, Sandra |
| المساهمون: | Neuro-Dol (Neuro-Dol), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Clermont Auvergne 2017-2020 (UCA 2017-2020 ), Université Clermont Auvergne 2017-2020, Paul Avan |
| المصدر: | https://theses.hal.science/tel-02426256Test ; Neurobiologie. Université Clermont Auvergne [2017-2020], 2019. Français. ⟨NNT : 2019CLFAS004⟩. |
| بيانات النشر: | HAL CCSD |
| سنة النشر: | 2019 |
| المجموعة: | HAL Clermont Auvergne (Université Blaise Pascal Clermont-Ferrand / Université d'Auvergne) |
| مصطلحات موضوعية: | Intracranial pressure, Tilt body position, Hydrocephalus, Subtractive lumbar puncture, Absorbance, Pression intracrânienne, Inclinaison du corps, Hydrocéphalie, Ponction lombaire soustractive, [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology |
| الوصف: | There is no validated non-invasive method for determining the absolute value of intracranial pressure (ICP). Ear connect cerebrospinal fluid (CSF) and cochlear fluid via cochlear aqueduct. The goal of this project is to use ear absorbance, optimal when the vibrating structures are in resting position, so the stapes when the pressure outside the ear (in the external ear canal -Peec) counteracts the ICP through the middle ear ossicles. Subjects are testing in different tilt body position, which increase ICP, using a tympanometer Wideband. 78 ears of control subjects between 20 and 30 years have shown that the absorbance is maximum at all frequencies at Peec = 0 mmH2O in standing posture, decreases in a complex way at zero Peec, but again identical to the maximum absorbance at Peec = 13 mm H2O ± 7 in supine, and 23 mm H2O ± 14 in Trendelenburg posture (-30 °), this in 68 ears out of 78. The remaining 10 ears had an anatomical dysfunction. A physical model was established from a classical electromechanical ear model, which reproduces the observed behavior by attributing to the ICP the cause of changes in absorbance and predicting the ability for Peec to offset the absorbance changes due to ICP. Furthermore, 3 patients treated with a perfusion test were tested as well as 2 patients treated by a lumbar puncture. These patients showed the effect of positives and negatives pressure in absorbance curves. Literature make possible a correlation between absolute ICP (in every tilt body position) and absorbance, we can conclude that due to the geometry of the middle ear, the equilibrium relationship between absolute values is ICP = 15 x Peec, where 15 is the ratio of the areas between the tympanic membrane and the stape plate. Subjects tested by invasive measurement of ICP will be required for the continuation of this study. ; Il n'existe pas de méthode non invasive validée pour déterminer la valeur absolue de la pression intracrânienne (PIC). Le liquide céphalorachidien (LCS) et le liquide cochléaire sont reliés par ... |
| نوع الوثيقة: | doctoral or postdoctoral thesis |
| اللغة: | French |
| العلاقة: | NNT: 2019CLFAS004; tel-02426256; https://theses.hal.science/tel-02426256Test; https://theses.hal.science/tel-02426256/documentTest; https://theses.hal.science/tel-02426256/file/2019CLFAS004_GONZALEZ_TORECILLA.pdfTest |
| الإتاحة: | https://theses.hal.science/tel-02426256Test https://theses.hal.science/tel-02426256/documentTest https://theses.hal.science/tel-02426256/file/2019CLFAS004_GONZALEZ_TORECILLA.pdfTest |
| حقوق: | info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.C0F2AC24 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |