التفاصيل البيبلوغرافية
| العنوان: |
The endogenous modulators of Ca2+–Mg2+-dependent ATPase in children with chronic kidney disease (CKD). |
| المؤلفون: |
Polak-Jonkisz, Dorota1 dpjonkisz@nefped.am.wroc.pl, Purzyc, Leszek2, Laszki-Szcząchor, Krystyna3, Musiał, Kinga1, Zwolińnska, Danuta1 |
| المصدر: |
Nephrology Dialysis Transplantation. Feb2010, Vol. 25 Issue 2, p438-444. 7p. 1 Chart, 4 Graphs. |
| مصطلحات موضوعية: |
*KIDNEY diseases, *CHRONIC diseases, *JUVENILE diseases, *ADENOSINE triphosphate, *CALCIUM, *HOMEOSTASIS |
| مستخلص: |
Background. Calcium homeostasis is disturbed in many ways in the course of chronic kidney disease (CKD). The concentration of free cytoplasmic calcium in erythrocytes is increased. Maintenance of a high concentration gradient (between the cystoplasmic and extracellular space) is possible only due to a finely tuned cooperation between many regulating systems in the cytoplasmic membranes and cell organelles. The aim of our study was to evaluate the activity of Ca2+–Mg2+-dependent ATPase (PMCA), calmodulin and calpain–calpastatin (CANP–CAST) system in erythrocytes of CKD children treated conservatively in the stages II–IV. [ABSTRACT FROM PUBLISHER] |
| قاعدة البيانات: |
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