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المؤلفون: Lisa Wolff, Siva Sankar Murthy Bandaru, Elias Eger, Hoai-Nhi Lam, Martin Napierkowski, Daniel Baecker, Carola Schulzke, Patrick J. Bednarski
المصدر: International Journal of Molecular Sciences
Volume 22
Issue 14
International Journal of Molecular Sciences, Vol 22, Iss 7631, p 7631 (2021)مصطلحات موضوعية: reactive oxygen species, pentathiepin, Molecular Structure, QH301-705.5, Antineoplastic Agents, Apoptosis, Glutathione, Article, Chemistry, Oxidative Stress, Structure-Activity Relationship, Glutathione Peroxidase GPX1, Cell Line, Tumor, sulfur, cancer cells, Humans, cytotoxicity, DNA damage, Biology (General), Thiepins, glutathione peroxidase, QD1-999, Cell Proliferation
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a7d2a658a7aaf555df3e4e6858275624Test
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المؤلفون: Łukasz Balewski, Anna Makowska, Patrick J. Bednarski, Franciszek Sączewski, Jarosław Sączewski
المصدر: Molecules
Volume 23
Issue 7
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules, Vol 23, Iss 7, p 1616 (2018)مصطلحات موضوعية: Acetonitriles, in vitro anticancer activity, Cell Survival, Pharmaceutical Science, Antineoplastic Agents, hybrid molecules, 2-imino-2H-chromen-3-yl-1,3,5-triazines, 01 natural sciences, Medicinal chemistry, Article, Analytical Chemistry, lcsh:QD241-441, Structure-Activity Relationship, lcsh:Organic chemistry, Cell Line, Tumor, Drug Discovery, Molecule, Cytotoxic T cell, Humans, Physical and Theoretical Chemistry, 2H-chromen-3-yl-1,3,5-triazines, Cell Proliferation, Aqueous solution, coumarins, Molecular Structure, 010405 organic chemistry, Chemistry, Triazines, Organic Chemistry, In vitro, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Chemistry (miscellaneous), Molecular Medicine, Drug Screening Assays, Antitumor, 2,4-diamino-1,3,5-triazines, 2-imino-coumarins, Human cancer
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a11ebb75ee043406f268c45df00d31Test
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المصدر: Molecules
Volume 23
Issue 6
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules, Vol 23, Iss 6, p 1497 (2018)مصطلحات موضوعية: quinolines, synthesis, Cell Survival, Pharmaceutical Science, Antineoplastic Agents, 1,2,4-triazoles, Ring (chemistry), 01 natural sciences, Medicinal chemistry, Article, Analytical Chemistry, lcsh:QD241-441, chemistry.chemical_compound, Structure-Activity Relationship, lcsh:Organic chemistry, Cell Line, Tumor, Drug Discovery, N-sulfonylhydrazones, in vitro antitumor activity, Moiety, Humans, structure, Physical and Theoretical Chemistry, Methylene, N-acylhydrazones, Benzotriazole, 010405 organic chemistry, Organic Chemistry, Quinoline, 1,2,4-Triazole, Triazoles, In vitro, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry, Chemistry (miscellaneous), Drug Design, Molecular Medicine, Chemical stability, hydrazones, 1,2,3-benzotriazoles
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::093c8a146fc70d3fa15ac84e61a5dd67Test
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المؤلفون: Łukasz Balewski, Franciszek Sączewski, Maria Gdaniec, Patrick J. Bednarski, Anna Makowska, Ewa Borys
المصدر: Molecules, Vol 19, Iss 10, Pp 17026-17051 (2014)
Molecules
Volume 19
Issue 10
Pages 17026-17051مصطلحات موضوعية: Models, Molecular, Stereochemistry, Pharmaceutical Science, chemistry.chemical_element, Antineoplastic Agents, 1-(2-pyridyl)imidazolidin-2-ones, Crystallography, X-Ray, Article, Analytical Chemistry, X-ray crystal structure analysis, lcsh:QD241-441, chemistry.chemical_compound, X-Ray Diffraction, lcsh:Organic chemistry, Coordination Complexes, Neoplasms, copper(II) complexes, Drug Discovery, Pyridine, Organometallic Compounds, Tumor Cells, Cultured, in vitro antitumor activity, Humans, Viability assay, Crystal violet, Physical and Theoretical Chemistry, Alkyl, Group 2 organometallic chemistry, chemistry.chemical_classification, Organic Chemistry, Thiones, Copper, In vitro, chemistry, Chemistry (miscellaneous), X-ray crystallography, 1-(2-pyridyl)imidazolidine-2-thiones, Molecular Medicine
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::444461dc96c1061544f8a1c82fa2fe59Test
http://www.mdpi.com/1420-3049/19/10/17026Test -
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المؤلفون: Kim S. Robinson, Luca Salassa, Virginia Appleyard, Karen Murray, Katharina Korpis, Aron F. Westendorf, Nicola J. Farrer, Renate Grünert, Peter J. Sadler, Julie A. Woods, Alastair M. Thompson, Patrick J. Bednarski
المصدر: Molecular Cancer Therapeutics
مصطلحات موضوعية: Cancer Research, Programmed cell death, Organoplatinum Compounds, Cell Survival, Ultraviolet Rays, Mice, Nude, Antineoplastic Agents, Apoptosis, HL-60 Cells, 010402 general chemistry, 01 natural sciences, Article, Inhibitory Concentration 50, Mice, chemistry.chemical_compound, Annexin, Autophagy, medicine, Animals, Humans, Cytotoxic T cell, Propidium iodide, Clonogenic assay, Cell Shape, Cisplatin, 010405 organic chemistry, Cell Cycle, Photochemical Processes, Xenograft Model Antitumor Assays, 0104 chemical sciences, Oncology, chemistry, Drug Resistance, Neoplasm, Cell culture, Immunology, Biophysics, Female, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96b41f080da70ff3f659c50f6473774bTest
https://doi.org/10.1158/1535-7163.mct-11-0959Test -
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المؤلفون: Karin Bracht, Thomas Kiefer, Patrick J. Bednarski, Gottfried Dölken
المصدر: Journal of Cancer Research and Clinical Oncology. 133:957-967
مصطلحات موضوعية: Adult, Male, Cancer Research, ATP Binding Cassette Transporter, Subfamily B, Lymphoma, B-Cell, Antineoplastic Agents, ATP-binding cassette transporter, Biology, Pharmacology, chemistry.chemical_compound, Cell Line, Tumor, medicine, Humans, MTT assay, Doxorubicin, ATP Binding Cassette Transporter, Subfamily B, Member 1, P-glycoprotein, Cell growth, Multidrug resistance-associated protein 2, Membrane Transport Proteins, Hydrogen Peroxide, General Medicine, Glutathione, Middle Aged, Multidrug Resistance-Associated Protein 2, Oncology, chemistry, Biochemistry, Drug Resistance, Neoplasm, Cell culture, biology.protein, ATP-Binding Cassette Transporters, Female, Multidrug Resistance-Associated Proteins, Oxidation-Reduction, Cell Division, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::972357dfb833c53e09ce19130d17dfc5Test
https://doi.org/10.1007/s00432-007-0241-xTest -
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المؤلفون: Michael Zielzki, Anja Wellner, Fiona Mackay, Renate Grünert, Patrick J. Bednarski, Peter J. Sadler
المصدر: Chemistry & Biology. 13(1):61-67
مصطلحات موضوعية: Azides, Light, Stereochemistry, Clinical Biochemistry, chemistry.chemical_element, Antineoplastic Agents, 010402 general chemistry, 01 natural sciences, Biochemistry, chemistry.chemical_compound, Inhibitory Concentration 50, Cell Line, Tumor, Neoplasms, Drug Discovery, medicine, Humans, Molecular Biology, Platinum, Cisplatin, Cell Nucleus, Pharmacology, Photosensitizing Agents, Molecular Structure, 010405 organic chemistry, Spectrum Analysis, Temperature, General Medicine, Adhesion, DNA, Prodrug, 3. Good health, 0104 chemical sciences, Mechanism of action, chemistry, Cell culture, Cancer cell, Biophysics, Molecular Medicine, medicine.symptom, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8916afe2830eb3027936aa62881236dTest
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المؤلفون: Patrick J. Bednarski, Nicole A. Kratochwil
المصدر: Journal of cancer research and clinical oncology. 125(12)
مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, Time Factors, Organoplatinum Compounds, Kinetics, Antineoplastic Agents, Biology, Drug Stability, Internal medicine, Extracellular, medicine, Tumor Cells, Cultured, Humans, Sulfhydryl Compounds, Cytotoxicity, chemistry.chemical_classification, Biological activity, General Medicine, Metabolism, In vitro, Culture Media, Endocrinology, Oncology, chemistry, Culture Media, Conditioned, Cancer cell, Thiol, Extracellular Space, Cell Division, Nuclear chemistry
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6f8d19d0543d39006373cb120b980b3Test
https://pubmed.ncbi.nlm.nih.gov/10592102Test -
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المصدر: Journal of cancer research and clinical oncology. 121(1)
مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, Organoplatinum Compounds, Antineoplastic Agents, Breast Neoplasms, Cell Count, chemistry.chemical_compound, Drug Stability, Internal medicine, Diamine, polycyclic compounds, medicine, Tumor Cells, Cultured, Humans, Receptor, Chromatography, High Pressure Liquid, Cisplatin, Chemistry, fungi, Biological activity, General Medicine, Blood Proteins, DNA, Ligand (biochemistry), In vitro, Culture Media, carbohydrates (lipids), Endocrinology, Oncology, Biochemistry, Receptors, Estrogen, Cancer cell, Growth inhibition, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::370e73cd5d639e5de0d8b85812d3b6f1Test
https://pubmed.ncbi.nlm.nih.gov/7860616Test