يعرض 1 - 10 نتائج من 545 نتيجة بحث عن '"validatie"', وقت الاستعلام: 0.93s تنقيح النتائج
  1. 1
    دورية أكاديمية

    المساهمون: Lectoraat Zorg en innovatie in de psychiatrie, NHL Stenden Hogeschool@@@Academie Gezondheidszorg

    المصدر: BMC Psychiatry. 23

    الوصف: This study evaluates psychometric properties of the Individual Recovery Outcomes Counter (I.ROC) in a Dutch population of participants with a schizophrenia spectrum disorder (SSD). B. Esther Sportel1*† , Hettie Aardema1†, Nynke Boonstra2 , Johannes Arends1 , Bridey Rudd3 , Margot J. Metz4 , Stynke Castelein5 and Gerdina H.M. Pijnenborg6

  2. 2
    مؤتمر

    المؤلفون: Groenboom, Rix

    الوصف: As part of the Cybersecurity Noord-Nederland project, the University of Groningen hosted a series of mini-lectures on cybersecurity. The lectures were given by experts in the field of cybersecurity. Each of the speakers has discussed cybersecurity threats, vulnerabilities as well as remedies from different perspectives.Software is the core part of all modern infrastructure and the main driver behind innovation in many (if not all) industries. And for safety and mission critical applications, software quality is paramount. This holds for so-called functional as well as non-functional aspects (such as security, performance, and compliance to quality standards).This presentation will give an overview of the methodologies and technologies that are applied to guarantee the correct functioning of core IT infrastructure. It will link the formal and legal requirements of software systems to practical and operational to ways how these requirements can be enforced.In particular will take a close look in how distributed systems are validated to demonstrate their correctness in context of its environment. For these API driven applications, so-called 'sandbox' environments are used that allow for the validation and certification of the information exchange. This concept is explained by using examples from different domains: banking (the PSD2 standard), eHealth (the Dutch MedMij framework) and the energy market.Rix Groenboom is lector (research professor) at the Hanze University of Applied sciences in the area of Digital Transformation. The research group, New Business and ICT, focusses on innovation using software in areas such as 5G, Cyber Security, eHeath and Smart Industry. Before joining the Hanze, he has spent over 20 years in the software quality industry in international technical sales and marketing positions, most recent as Strategic Innovations Manager for Parasoft. He is specialist in testing and validation of modern SOA, SaaS and cloud architectures. He has written a large number of technical articles and presented on many IT conferences. His core expertise is specification, design and validation of software applications. An overview of his publications can be found here.

  3. 3
    دورية أكاديمية
  4. 4
    دورية أكاديمية

    المؤلفون: Nieuwboer, Christa, Veninga, Petra

    المساهمون: Lectoraat Jeugd, Gezin en Samenleving, Avans Hogeschool, Expertisecentrum Caring Society 3.0, Avans Hogeschool

    المصدر: Tijdschrift voor Orthopedagogiek. 57(11/12)

    مصطلحات موضوعية: Voorlichting, Gezondheid, Digitale media, Betrouwbaarheid, Validatie

    الوصف: Door het open karakter van het internet circuleert er veel desinformatie over opvoeding. Gedegen kwaliteitskaders voor professionele voorlichting ontbreken echter. In Nederland is een unieke werkwijze ontwikkeld, die gebaseerd is op de principes van evidence-based practice: door wetenschappelijke kennis, vakkennis en ervaringskennis te combineren ontstaat 'de beste informatie voor de meeste ouders'. Informatie is alleen effectief en overtuigend als deze aansluit bij de omstandigheden en waarden van het individu. De gezondheidsprofessional kan met behulp van deze gevalideerde online hulpbron informatierecepten uitschrijven en afstemmingsgesprekken voeren over de unieke opvoedsituatie.

  5. 5
    دورية أكاديمية

    المصدر: Sports Biomechanics.

    الوصف: Wearable inertial sensors (WIS) facilitate the preservation of the athlete-environment relationship by allowing measurement outside the laboratory. WIS systems should be validated for team sports movements before they are used in sports performance and injury prevention research. The aim of the present study was to investigate the concurrent validity of a wearable inertial sensor system in quantifying joint kinematics during team sport movements. Ten recreationally active participants performed change-of-direction (single-leg deceleration and sidestep cut) and jump-landing (single-leg hop, single-leg crossover hop, and double-leg vertical jump) tasks while motion was recorded by nine inertial sensors (Noraxon MyoMotion, Noraxon USA Inc.) and eight motion capture cameras (Vicon Motion Systems Ltd). Validity of lower-extremity joint kinematics was assessed using measures of agreement (cross-correlation: XCORR) and error (root mean square deviation; and amplitude difference). Excellent agreement (XCORR >0.88) was found for sagittal plane kinematics in all joints and tasks. Highly variable agreement was found for frontal and transverse plane kinematics at the hip and ankle. Errors were relatively high in all planes. In conclusion, the WIS system provides valid estimates of sagittal plane joint kinematics in team sport movements. However, researchers should correct for offsets when comparing absolute joint angles between systems.

  6. 6
    كتاب

    المصدر: Dautzenberg , G M F C 2022 , ' Trust me, I’m a validated test!? Unseen mild (cognitive) impairment and the use of the MoCA in an old age psychiatry setting. ' , PhD , Vrije Universiteit Amsterdam , s.l. .

    الوصف: In clinical practice two seemingly distinct disorder clusters are referred to the old age psychiatry; psychiatric disorders and neurodegenerative disorders. However, both psychiatric and neurodegenerative causes can start with (mild) cognitive deficits. An elaborate neuropsychological assessment is part of the gold standard for identifying the cause. As it is expensive and burdensome for the patient to do this in specialised outpatient clinics, a triaging test before a referral is made is desirable. A fast test with discriminatory power in this group of patients with a non-uniform presentation is of great value as an increasing number of people have dementia; they are examined earlier in the process, and this interferes with regular (psychiatric) treatments and complicates diagnostics due to increasing overlapping symptom presentation. This test should be validated to allow the scores to be interpreted properly so it can help to identify or exclude (mild) cognitive impairment. The Montreal Cognitive Assessment (MoCA) is a short screening test (10 minutes long) for cognitive complaints but it was not validated in old age psychiatry. Not only did we validated the MoCA for this setting, we also show how to improve its use in clinical practice by using a double threshold. In addition to the preceding summary one must consider that patients tend not to mention all of their needs during visits. The symptoms experienced do not always have to correspond to their objective symptoms. This also applies for what close relatives report. Therefore, we must be aware of that patients are not always able to properly draw attention to their request for help or, in fact, the cause of their complaints. Screening could be a solution, but often comes with costs. To screen or not to screen – that is often the question. In this dissertation, we have provided the arguments that the MoCA can play a substantial role colouring the grey area that this question raises. Therefore allowing (part of) this discussion to be settled for cognitive ...

    وصف الملف: application/pdf; image/jpeg; application/vnd.openxmlformats-officedocument.wordprocessingml.document

  7. 7
    دورية أكاديمية

    المؤلفون: Margot I, Visser-Bochane, Healthy Ageing, Allied Health Care and Nursing, Cees P, van der Schans, Healthy Ageing, Allied Health Care and Nursing, Wim P, Krijnen, Healthy Ageing, Allied Health Care and Nursing, Sijmen A, Reijneveld, Margreet R, Luinge, Healthy Ageing, Allied Health Care and Nursing, Healthy Ageing, Allied Health Care and Nursing

    المصدر: European Journal of Pediatrics. 180(1):63-71

    الوصف: The aim of this study was to assess the criterion validity of a new screening instrument, the Early Language Scale (ELS), for the identification of young children at risk for developmental language disorder (DLD), and to determine optimal age-adjusted cut-off scores. We recruited a community-based sample of 265 children aged 1 to 6 years of age. Parents of these children responded on the ELS, a 26-item 'yes-no' questionnaire. The children were assessed with extended language tests (language comprehension, word production, sentence production, communication). A composite score out of these tests (two tests below - 1 SD or one below - 1.5 SD) was used as reference standard. We assessed the validity of the ELS, measured by sensitivity, specificity, predictive values, and AUC. The optimal sensitivity/specificity age-dependent cut-off ELS score was at 15th percentile. Sensitivity and specificity were 0.62 and 0.93, respectively. Positive predictive value was moderate (0.53), negative predictive value was high (0.95), the positive likelihood ratio was 9.16, and negative likelihood ratio was 0.41. The area under the ROC curve was 0.88. The items covered the increasing language development for the ages from 1 to 6.Conclusion: The ELS is a valid instrument to identify children with DLD covering an age range of 1 to 6 years in community-based settings.What is Known:• Early identification and treatment of developmental language disorders can reduce negative effects on children's emotional functioning, academic success, and social relationships.• Short, validated language screening instruments that cover the full age range of early childhood language development lack.What is New:• The 26-item Early Language Scale (ELS) is a valid instrument to identify children at risk for developmental language disorder in well-child care and early educational settings among Dutch children aged 1-6 years.

  8. 8
    كتاب

    المؤلفون: Thijssen, Elisabeth Hubertina

    المصدر: Thijssen , E H 2021 , ' Blood-based biomarkers for Alzheimer’s disease : Assay development and clinical validation ' , Dr. , Vrije Universiteit Amsterdam .

    الوصف: In the past five years, major progress has been made in the field of blood-based biomarkers. This thesis shows that the key pathological hallmarks of AD, being amyloid aggregation, tau accumulation, neurodegeneration, and astrocytosis, can be reflected with biomarker measurements in blood. We found that biomarker concentrations vary across different neurodegenerative diseases and are thus valuable for differential diagnosis. We developed and validated an assay to measure the Abeta42/40 ratio in plasma, that reflected amyloid-PET positivity. Plasma P-tau181 and P-tau217 were specifically increased in participants with Alzheimer’s pathology. And NfL and GFAP contributed to biomarker panels for differential diagnosis. In addition, we developed a CSF assay that can detect acetylated tau, important for monitoring of treatment effect of tau acetylation targeting therapies. Nevertheless, there are some challenges ahead on the road to clinical implementation. The optimal panel of biomarkers for different diagnostic questions should be further established and tested in a real-world setting. Then the appropriate steps can be taken to implement blood-based biomarkers in daily clinical practice for diagnosis of AD.

    وصف الملف: application/pdf; image/jpeg

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    المؤلفون: Tieleman, Sebastiaan Benjamin

    المساهمون: Faculteit REBO, UU LEG Research UUSE Multidisciplinary Economics, Boumans, Marcel, van Marrewijk, Charles

    الوصف: The main aim of this dissertation is to contribute to the systematic understanding of modeling practices within macroeconomics. As its chosen method, it analyzes three particular cases, which, each in their own way, may be taken to be representative of modeling practices today. Subsequently, the results from the case studies are integrated and evaluated. The first case is discussed in Chapter 2 and focuses on the empirical validation of macroeconomic agent-based models. It is shown that agent-based models in macroeconomics can be best understood by considering them as complex systems with a multitude of interaction levels. Empirical validation tests, as observed in practice, can be related to these levels of interaction. Furthermore, I distinguish between validation tests directed at the model target and the model structure and consider how these apply to macroeconomic agent-based models. The second case is discussed in Chapter 3 and concentrates on the shift in dynamic stochastic general equilibrium (DSGE) models from being calibrated to being estimated. Estimation is considered preferable to calibration for several reasons, in particular because it allows for the parametrization of models with a large number of parameters. In turn, this makes possible the construction of larger models that incorporate more of the complexity of the real-world economic system. This shift required DSGE models to evolve into what I label as a ‘hybrid model structure’, which is a model with a representational core supplemented with non-representational stochastic elements. This hybrid model structure has come under fire from several authors. I argue that this critique is warranted if it is understood as a disruption in the relationship between the outcome of an empirical validation test and the validity of the model. The third case, presented in Chapter 4 and discusses interdomain model transfer. The case studied is that of the Yule process, a model originally developed in evolutionary biology but later reused as a model for firm growth. The aim of the chapter is to provide an explanation of why such model transfer may appear. It presents a framework of model transfer in which the various validation criteria distinguished in Chapter 3 play a central role. A model is transferred from an original to a new domain when it is found to be useful in both domains. This is the case when overlap is found between the validation criteria of both domains. Special attention is paid here to overlap between phenomenological criteria, which is enabled through the existence of observed universal patterns. Overlap of this type is an important explanation in the case of the Yule process. The main result of this dissertation is the model construction framework presented in Chapter 5. In this framework, the insights of the case studies are integrated. The framework is centered on the concepts of model purpose, invariance, model validation, and model scope, as well as how these concepts fit together. Ultimately, this is a framework that provides a systematic understanding of macroeconomic modeling practice. .

    وصف الملف: application/pdf

  10. 10
    دورية أكاديمية

    المصدر: Tijdschrift voor Gerontologie en Geriatrie, Vol 50, Iss 4 (2019)

    مصطلحات موضوعية: EAT-10, orofaryngeale dysfagie, ouderen, validatie, Medicine

    الوصف: De prevalentie van orofaryngeale dysfagie (OD) bij ouderen >76j wordt geschat op 26%. OD kan leiden tot malnutritie, depressie, vermindering van de levenskwaliteit en verhoogde mortaliteit bij ouderen. Ondanks deze belangrijke complicaties wordt OD vaak niet ontdekt door het gebrek aan een betrouwbaar en makkelijk toepasbaar screeningsinstrument. De Eating Assessment Tool-10 (EAT-10) vragenlijst bestaat uit tien stellingen die symptomen en tekens van OD bevraagt. In de huidige literatuur wordt een afkapwaarde van ≥3 punten aangehouden ter bepaling vanaf wanneer er een risico voor OD bestaat. De EAT-10 vragenlijst vertoont een goede interne consistentie en test-hertest-betrouwbaarheid en is gevalideerd in verschillende talen met vergelijkbare resultaten. Het doel van de huidige studie is de validatie van de EAT-10 vragenlijst in het Nederlands. De resultaten tonen een sterke test-hertest-betrouwbaarheid (Spearmans rho 0,841) en een interne consistentie van 0,917 via Cronbachs alfa. De Nederlandstalige EAT-10 vragenlijst is in een klinische omgeving goed toepasbaar met een gemiddelde afnameduur van 2 minuten en 28 seconden (± 1 minuut en 32 seconden). Validatie van de Nederlandstalige EAT-10 vragenlijst maakt screening van OD bij een Nederlandstalige (oudere) populatie mogelijk.

    وصف الملف: electronic resource