المؤلفون: Ranran Xu, Fei Huang, Qingquan Liu, Yongman Lv, Liu Hu, Qian Zhang

المصدر: Renal Failure, Vol 46, Iss 1 (2024)

مصطلحات موضوعية: USP25, anti-GBM GN, Th17 cells, RORγt, Diseases of the genitourinary system. Urology, RC870-923

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/0886-022XTest; https://doaj.org/toc/1525-6049Test

الوصول الحر: https://doaj.org/article/d243aebfe1b64dc499fbb1d793f60017Test

المؤلفون: Arger, Nicholas K, Machiraju, Siddharth, Allen, Isabel E, Woodruff, Prescott G, Koth, Laura L

مصطلحات موضوعية: Lung, Bronchoalveolar Lavage Fluid, Humans, Sarcoidosis, Pulmonary, T-Box Domain Proteins, Prognosis, Case-Control Studies, Adult, Aged, Middle Aged, Female, Male, Interferon-gamma, Nuclear Receptor Subfamily 1, Group F, Member 3, Th17 Cells, Biomarkers, RORγt, T-bet, Th1, Th17, Th17.1, chemokine, interferon-gamma, sarcoidosis, Autoimmune Disease, Clinical Research, 2.1 Biological and endogenous factors, Aetiology, Inflammatory and immune system, 1, ROR gamma t, Immunology, Medical Microbiology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/922531z9Test

المؤلفون: Lixue Lu, Yafei Huang, Meiqi Song, Nannan Sun, Li Xia, Mingcheng Yu, Meiling Zhao, Ruomeng Qiu, Ji-an Chen, Yunpeng Zhao, Haojie Wang, Huimin Guo, Yan Li, Di Zhu, Yonghui Wang, Qiong Xie

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Immunology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, sup >+, preclinical tumor models, mouse b16f10 melanoma, llc lung adenocarcinoma, demonstrated robust efficacy, current studies indicate, biaryl amide derivatives, rorγt agonists provide, novel rorγt agonists, 14 , vivo <, taken together, reachable approach, pharmacokinetic profiles, cancer immunotherapy

العلاقة: https://figshare.com/articles/journal_contribution/Discovery_of_Biaryl_Amide_Derivatives_as_Potent_Selective_and_Orally_Bioavailable_ROR_t_Agonists_for_Cancer_Immunotherapy/24591888Test

الإتاحة: https://doi.org/10.1021/acs.jmedchem.3c01492.s001Test
https://figshare.com/articles/journal_contribution/Discovery_of_Biaryl_Amide_Derivatives_as_Potent_Selective_and_Orally_Bioavailable_ROR_t_Agonists_for_Cancer_Immunotherapy/24591888Test

المؤلفون: Dehui Chang, Hao Zhang, Jing Ge, Qi Xing, Xinyi Guo, Xiaohu Wang, Chen Dong

المصدر: Frontiers in Immunology, Vol 14 (2023)

مصطلحات موضوعية: ILC3s, RORγt, CNS9, cis-element, plasticity, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1105145/fullTest; https://doaj.org/toc/1664-3224Test

الوصول الحر: https://doaj.org/article/bf51c132db0b4eb3a1d6cc5a6158adfdTest

المؤلفون: Li Xia, Enming Tian, Mingcheng Yu, Chenglong Liu, Lian Shen, Yafei Huang, Zhongen Wu, Jinlong Tian, Ker Yu, Yonghui Wang, Qiong Xie, Di Zhu

المصدر: Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-23 (2022)

مصطلحات موضوعية: RORγt, Th17, CXCL10, Tumor microenvironment, Immunotherapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1756-9966Test

الوصول الحر: https://doaj.org/article/75b90835d1124728851ce9db56e3fc3dTest

المؤلفون: Mohamed E. Shaker, Mohamed F. Hamed, Ahmed A. Shaaban

المصدر: Saudi Pharmaceutical Journal, Vol 30, Iss 3, Pp 291-299 (2022)

مصطلحات موضوعية: Sterile inflammation, DAMPs, NLRP3, RORγt, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S131901642200007XTest; https://doaj.org/toc/1319-0164Test

الوصول الحر: https://doaj.org/article/204dfc1e551b4c87b29edadee2f08c56Test

المؤلفون: Valle Noguera, Ana, Sancho Temiño, Lucía, Castillo González, Raquel, Villa Gómez, Cristina, Gomez Sánchez, María José, Ochoa Ramos, Anne, González Granado, José María, Cruz Adalia, Aranzazu

مصطلحات موضوعية: 612.017, CP: Immunology, Citrobacter rodentium, HIF-1α, IL-18, IL-22, TLR2, colitis, group 3 innate lymphoid cells, infection, innate RORγt(+) cells, Inmunología, 2412.99 Otras

وصف الملف: application/pdf

العلاقة: info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/RTI2018-093647-B-I00/ES/CONTROL DE LA REGULACION METABOLICA Y MOLECULAR MEDIADA POR HIF-1A EN LAS CELULAS INNATAS LINFOIDES/; PID2021-122780OB-I00; CNS2022-135365; info:eu-repo/grantAgreement/ISCIII/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020 (ISCIII)/PI20%2F00306/ES/INMUNOLOGIA, INMUNOPATOLOGIA Y TERAPIA EN ENFERMEDAD INFLAMATORIA INTESTINAL/; https://hdl.handle.net/20.500.14352/92186Test; Valle-Noguera A, Sancho-Temiño L, Castillo-González R, Villa-Gómez C, Gomez-Sánchez MJ, Ochoa-Ramos A, Yagüe-Fernández P, Soler Palacios B, Zorita V, Raposo-Ponce B, González-Granado JM, Aragonés J, Cruz-Adalia A. IL-18-induced HIF-1α in ILC3s ameliorates the inflammation of C. rodentium-induced colitis. Cell Rep. 2023 Dec 26;42(12):113508. doi:10.1016/j.celrep.2023.113508. Epub 2023 Nov 28. PMID: 38019650.; https://www.sciencedirect.com/journal/cell-reportsTest

الإتاحة: https://doi.org/20.500.14352/92186Test
https://doi.org/10.1016/j.celrep.2023.113508Test
https://hdl.handle.net/20.500.14352/92186Test
https://www.sciencedirect.com/journal/cell-reportsTest

المؤلفون: Elmeri M. Jokinen, Miika Niemeläinen, Sami T. Kurkinen, Jukka V. Lehtonen, Sakari Lätti, Pekka A. Postila, Olli T. Pentikäinen, Sanna P. Niinivehmas

المصدر: Molecules; Volume 28; Issue 8; Pages: 3420

مصطلحات موضوعية: molecular docking, docking rescoring, negative image-based rescoring (R-NiB), brute force negative image-based optimization (BR-NiB), pharmacophore (PHA) filtering, retinoic acid receptor-related orphan receptor gamma t (RORγt), virtual screening (VS), inflammation

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Medicinal Chemistry; https://dx.doi.org/10.3390/molecules28083420Test

الإتاحة: https://doi.org/10.3390/molecules28083420Test

المؤلفون: Marta Szandruk-Bender, Beata Nowak, Anna Merwid-Ląd, Alicja Z. Kucharska, Małgorzata Krzystek-Korpacka, Iwona Bednarz-Misa, Benita Wiatrak, Adam Szeląg, Narcyz Piórecki, Tomasz Sozański

المصدر: Molecules; Volume 28; Issue 7; Pages: 3034

مصطلحات موضوعية: experimental colitis, TNBS, Th17/Treg axis, IL-6, RORγt, STAT3, Foxp3, PIAS3, cornelian cherry, polyphenols

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Natural Products Chemistry; https://dx.doi.org/10.3390/molecules28073034Test

الإتاحة: https://doi.org/10.3390/molecules28073034Test

المؤلفون: Kuznetsova D.A., Lapin S.V., Gubonina I.V.

المساهمون: 1

المصدر: Almanac of Clinical Medicine; Vol 51, No 1 (2023); 1-13 ; Альманах клинической медицины; Vol 51, No 1 (2023); 1-13 ; 2587-9294 ; 2072-0505

مصطلحات موضوعية: bile acids, bile acid metabolism, bile acid malabsorption, gut microbiota, FXR, GPBAR1, PXR, RORγt, VDR, inflammatory bowel diseases, желчные кислоты, метаболизм желчных кислот, мальабсорбция желчных кислот, микробиота кишечника, воспалительные заболевания кишечника

وصف الملف: application/pdf

العلاقة: https://almclinmed.ru/jour/article/view/7708/1552Test; https://almclinmed.ru/jour/article/downloadSuppFile/7708/61920Test; https://almclinmed.ru/jour/article/downloadSuppFile/7708/61926Test; https://almclinmed.ru/jour/article/downloadSuppFile/7708/93792Test; https://almclinmed.ru/jour/article/downloadSuppFile/7708/93802Test; https://almclinmed.ru/jour/article/downloadSuppFile/7708/93812Test; https://almclinmed.ru/jour/article/downloadSuppFile/7708/93813Test; https://almclinmed.ru/jour/article/view/7708Test

الإتاحة: https://doi.org/10.18786/2072-0505-2023-51-007Test
https://almclinmed.ru/jour/article/view/7708Test